Menopausal Symptoms Are Associated With Oral Sensory Complaints in Perimenopausal Women: An Observational Study

2021 ◽  
Author(s):  
Tomoharu Taga ◽  
Kayoko Ito ◽  
Kiyoshi Takamatsu ◽  
Mariko Ogawa ◽  
Saori Funayama ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Univariate Analysis ◽  
Menopausal Symptoms ◽  
Study Cohort ◽  
Tongue Coating ◽  
Taste Disturbance ◽  
Factors Associated ◽  
Oral Sensory ◽  
Perimenopausal Women ◽  
Burning Mouth

Abstract Background: Perimenopausal women experience a wide variety of systemic symptoms: hot flashes, sweating, psychiatric symptoms and various oral sensory complaints (OSC). OSC in perimenopausal women include xerostomia, taste disturbance and burning mouth. However, the factors associated with these OSC have not been identified. The purpose of this investigation was to elucidate the factors associated with OSC in perimenopausal women．Methods: The study cohort comprised 43 perimenopausal women aged 45–55 years. Data on medical history, medications, menstrual status, menopausal symptoms, xerostomia, taste disturbance and burning mouth were collected. Volumes of unstimulated and stimulated saliva were measured. Tongue coating was evaluated according to a tongue coating index. Univariate analysis was performed to identify factors significantly associated with having xerostomia, taste disturbance, burning mouth and more than two OSC (2OSC). Next, the factors strongly associated with these symptoms were examined by logistic regression analysis.Results: The number of menopausal symptoms was significantly higher, and volume of unstimulated saliva significantly lower in participants with xerostomia, taste disturbance, burning mouth or 2OSC than in those without these characteristics. Agents targeting the central nervous system were more frequently taken by participants with burning mouth and 2OSC than by those without these characteristics. According to logistic regression analysis, the number of menopausal symptoms was an explanatory variable for xerostomia, taste disturbance, burning mouth and 2OSC. Conclusions: Our findings suggested that OSC associated with the number of menopausal symptoms. Management of menopausal symptoms may decrease OSC, leading to improved quality of life of perimenopausal women.

scholarly journals Menopausal symptoms are associated with oral sensory complaints in perimenopausal women: an observational study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Tomoharu Taga ◽  
Kayoko Ito ◽  
Kiyoshi Takamatsu ◽  
Mariko Ogawa ◽  
Saori Funayama ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Regression Analysis ◽  
Menopausal Symptoms ◽  
Tongue Coating ◽  
Taste Disturbance ◽  
Factors Associated ◽  
Oral Sensory ◽  
Perimenopausal Women ◽  
Burning Mouth

Abstract Background Perimenopausal women experience a wide variety of systemic symptoms: hot flashes, sweating, mental health concerns and various oral sensory complaints (OSC). OSC in perimenopausal women include xerostomia, taste disturbance and burning mouth. However, the factors associated with these OSC have not been identified. The purpose of this investigation was to elucidate the factors associated with OSC in perimenopausal women. Methods The study cohort comprised 43 perimenopausal women aged 45–55 years. Data on medical history, medications, menstrual status, menopausal symptoms, quality of life, xerostomia, taste disturbance and burning mouth were collected. Volumes of unstimulated and stimulated saliva were measured. Tongue coating was evaluated according to a tongue coating index. Univariate analysis was performed to identify factors significantly associated with having xerostomia, taste disturbance, burning mouth and more than two OSC (2OSC). Next, the factors strongly associated with these symptoms were examined by logistic regression analysis. Results The number of menopausal symptoms was significantly higher, and volume of unstimulated saliva was significantly lower in participants with xerostomia, taste disturbance, burning mouth or 2OSC than in those without these characteristics. Agents targeting the central nervous system were more frequently taken by participants with burning mouth and 2OSC than by those without these characteristics. According to logistic regression analysis, the number of menopausal symptoms was an explanatory variable for xerostomia, taste disturbance, burning mouth and 2OSC. Conclusions Our findings suggested that OSC associated with the number of menopausal symptoms. Management of menopausal symptoms may decrease OSC, leading to improved quality of life of perimenopausal women.

scholarly journals Language Delay Is Not Predictable from Available Risk Factors

2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Philip Wilson ◽  
Fiona McQuaige ◽  
Lucy Thompson ◽  
Alex McConnachie
Keyword(s):  
Risk Factors ◽  
Logistic Regression ◽  
Positive Predictive Value ◽  
Predictive Value ◽  
Univariate Analysis ◽  
Male Gender ◽  
Language Delay ◽  
Predictive Capacity ◽  
Factors Associated ◽  
Health Visitors

Aims. To investigate factors associated with language delay in a cohort of 30-month-old children and determine if identification of language delay requires active contact with families.Methods. Data were collected at a pilot universal 30-month health contact. Health visitors used a simple two-item language screen. Data were obtained for 315 children; language delay was found in 33. The predictive capacity of 13 variables which could realistically be known before the 30-month contact was analysed.Results. Seven variables were significantly associated with language delay in univariate analysis, but in logistic regression only five of these variables remained significant.Conclusion. The presence of one or more risk factors had a sensitivity of 89% and specificity of 45%, but a positive predictive value of only 15%. The presence of one or more of these risk factors thus can not reliably be used to identify language delayed children, nor is it possible to define an “at risk” population because male gender was the only significant demographic factor and it had an unacceptably low specificity (52.5%). It is not possible to predict which children will have language delay at 30 months. Identification of this important ESSENCE disorder requires direct clinical contact with all families.

scholarly journals Factors associated with pericolic fat stranding of colon cancer on computed tomography colonography

2018 ◽  
Vol 7 (2) ◽  
pp. 205846011875757
Author(s):  
Tsuyoshi Morimoto ◽  
Takayuki Yamada ◽  
Kunihisa Miyakawa ◽  
Yasuo Nakajima
Keyword(s):  
Computed Tomography ◽  
Colon Cancer ◽  
Logistic Regression ◽  
Lymph Node ◽  
Univariate Analysis ◽  
Depth Of Invasion ◽  
Factors Associated ◽  
Longitudinal Length ◽  
Fat Stranding ◽  
Group Comparisons

Background Pericolic fat stranding on computed tomography (CT) scans has been an important feature for staging colon cancer. However, the factors associated with pericolic fat stranding have not been elucidated to date. Purpose To determine factors associated with pericolic fat stranding of colon cancer on CT colonography (CTC). Material and Methods Overall, 150 patients with 155 colon cancer lesions were retrospectively assessed by two radiologists for pericolic fat stranding on CTC. Circumferential proportion of the tumor (CPtumor; <50%, 50–75%, and ≥75%), longitudinal length, depth of invasion (≤T2, T3, T4), lymph node and distant metastasis, and lymphovascular invasion were recorded. Univariate and multivariate logistic regression analyses were performed between pericolic fat stranding and each factor. Multi-group comparisons were performed for the CPtumor and depth of invasion. Results Pericolic fat stranding was identified in 57 lesions (36.8%). Univariate analysis revealed significant associations of pericolic fat stranding with all factors ( P < 0.027), except for lymph node metastasis ( P = 0.087). Multi-group comparisons revealed that pericolic fat stranding was more frequent with increasing CPtumor ( P < 0.001); however, no significant differences were observed beyond subserosal infiltration ( P = 0.225). Logistic regression analysis revealed the CPtumor (<75% vs. ≥75%; P = 0.008, <50% vs. 50–75%; P = 0.047) and longitudinal length ( P = 0.001) as explainable variables. Conclusion Pericolic fat stranding identified on CT images of colon cancer is demonstrated more frequently with increasing circumferential proportion of the tumor and longitudinal length.

scholarly journals Prevalence and associated factors for Pterygium in Han and Mongolian adults: across-sectional study in inner Mongolian, China

2019 ◽  
Author(s):  
Yuhan Wang ◽  
Guangliang Shan ◽  
Linyang Gan ◽  
Yonggang Qian ◽  
Ting Chen ◽  
...  
Keyword(s):  
Risk Factors ◽  
Protective Factors ◽  
Rural Areas ◽  
Inner Mongolia ◽  
Univariate Analysis ◽  
Education Level ◽  
Study Cohort ◽  
Sectional Study ◽  
Factors Associated ◽  
Significant Difference

Abstract Background: To investigate the prevalence of and factors associated with pterygium in Han and Mongolian adults at four survey sites in Inner Mongolia, China. Methods: A population-based, cross-sectional study was conducted. Using a stratified sampling method, we eventually included 2,651 participants of at least30 years of age from a total of 3,468 eligible residents. Factors associated with pterygium were analysed using univariate analysis and logistic regression models. Results: There were 1,910 Han adults and 741 Mongolian adults included in this study. The mean± standard deviation of age for individuals in the study cohort was 48.93±11.06 years. The overall prevalence of pterygium was 6.4% (n=169), and the prevalences of bilateral and unilateral pterygium were 1.4% (n=38) and 4.8% (n=128), respectively. The most common grade of pterygium was Grade 2. After univariate analysis, eleven factors were considered in a multivariate analysis. The results indicated that age (P<0.001), education level (P<0.001), outdoor occupation (P=0.026), and time spent in rural areas (P<0.001) were significantly associated with pterygium, whereas gender and ethnicity were not risk factors. In subgroup analysis, BMI≥28 was a protective factor for Han individuals (OR 0.42, 95% CI 0.21-0.81, P=0.01), but a risk factor for Mongolian individuals (OR 2.39, 95% CI 1.02-5.58, P=0.044). The BF% in Han and Mongolian individuals had significant difference (P<0.001). Conclusions: Our results indicated that an outdoor occupation, old age and time spent in rural areas are risk factors for pterygium in Inner Mongolia. Living near an urban survey site (Hohhot and Tsining District) and having a higher education level are protective factors for pterygium. Ethnicity, gender, smoking, diabetes and high blood pressure are not associated with pterygium. Different dietary structures in Han and Mongolian adults may lead to different fat content of body and therefore contributes to the prevalence of pterygium. Keywords: Pterygium, prevalence, Han and Mongolian, risk factors, protective factors

scholarly journals Family planning uptake in Kagera and Mara regions in Tanzania: a cross-sectional community survey

2020 ◽  
Author(s):  
Joseph Batholomeo Massenga ◽  
Ritha Norohna ◽  
Bayoum Awadhi ◽  
Dunstan Bishanga ◽  
Oliva Safari ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Family Planning ◽  
Community Health ◽  
Univariate Analysis ◽  
Unmet Need ◽  
Reproductive Age ◽  
P Value ◽  
Cross Sectional ◽  
Mixed Effect ◽  
Factors Associated

Abstract BackgroundIn Tanzania, 27.1% of all women of reproductive age are currently using modern contraception, and 16.8% have an unmet need for family planning. We therefore examined factors associated with family planning uptake after giving birth in two regions of Tanzania.MethodsSub-analysis of a cross-sectional household survey conducted in April 2016 in Mara and Kagera regions in Tanzania. A total of 1184 women aged 15-49 years, who had given birth less than two years prior to the survey were included. Logistic regression mixed effect modelling was used to examine factors associated with family planning uptake. Univariate analysis was used to present crude effects of covariates, followed by stepwise forward selection to build a multiple logistic regression model. A p-value ≥ 0.20 was applied as the criterion to retain a variable into the model.ResultsAmong 1184 women within two years after giving birth, 393 (33.2%) used family planning methods. After adjusting for (1) age, (2) level of education, (3) living in union, (4) being accompanied to ANC by a partner and (5) being able to mention at least one method, factors independently associated with family planning uptake included: (1) having discussed family planning with the partner (aOR 2.90; 95% CI 1.88-4.49), (2) having been counselled on family planning during ANC (aOR 2.15; 95% CI 1.48-3.13), (3) having discussed family planning with a community health worker (aOR 3.32; 95% CI 1.91-5.77), (4) having discussed family planning with a facility health care worker (aOR 1.79; 95% CI 1.22-2.62), (5) having primary or higher educational level (aOR 1.66; 95% CI 1.01-2.273) and (6) being in union (aOR 1.86; 95% CI 1.02-3.42).ConclusionSupportive constitutes including educational interaction with facility and community health workers, as well as having a supportive partner are facilitators to increased uptake of family planning among women in Tanzania

Factors associated with increased incidence of toxicities following administration of yttrium-90 resin microspheres.

2015 ◽  
Vol 33 (3_suppl) ◽  
pp. 409-409
Author(s):  
John Roberson ◽  
Andrew M. McDonald ◽  
Craig Joseph Baden ◽  
Rojymon Jacob ◽  
Omer L. Burnett
Keyword(s):  
Logistic Regression ◽  
Colorectal Adenocarcinoma ◽  
Univariate Analysis ◽  
White Blood Cells ◽  
Binary Logistic Regression ◽  
Factors Associated ◽  
Laboratory Values ◽  
Pre Treatment ◽  
Lung Shunt ◽  
Yttrium 90

409 Background: To further define factors associated with increased incidences of hepatic, constitutional, and gastrointestinal toxicities following administration of yttrium-90 (90Y) microspheres in a sequential cohort of heterogeneous patients. Methods: Fifty-seven patients who underwent 76 treatments were assessed for toxicity incidence following 90Y administration. Post-treatment clinical and liver function test (LFT) toxicities were assessed using Common Terminology Criteria for Adverse Events version 4.03. Binary logistic regression was used to evaluate the univariate effect of factors on toxicity incidences. A multivariate binary logistic regression model was performed for each toxicity using all factors with a p < 0.10 on univariate analysis. Results: Hepatic toxicities, including LFT toxicities, were present following 46.1% of treatments, while gastrointestinal and constitutional toxicities were present following 57.3% and 55.3%, respectively. Multivariate analyses revealed that colorectal adenocarcinoma, age at time of treatment, intraprocedural stasis, decreased Karnofsky Performance Status, increased body mass index (BMI), and decreased lung shunt were statistically significant (p < 0.05) predictors for increased incidence of toxicities most prevalent among our cohort. Increased pre-treatment laboratory values including albumin, alkaline phosphatase, total bilirubin, and white blood cells were also statistically significant predictors. Conclusions: Colorectal adenocarcinoma, declining functional status, decreased lung shunt, and increased pre-treatment laboratory values should be given more clinical attention when attempting to limit toxicities and improve the quality of life in patients following 90Y treatment. Specific constitutional, gastrointestinal, and hepatic toxicities including weakness, loss of appetite, and laboratory abnormalities are also associated with patients’ age, increased BMI, and intraprocedural stasis.

scholarly journals Epidemiology of Hospitalizations Due to Autoimmune Hemolytic Anemia in the United States

Blood ◽  
2021 ◽  
Vol 138 (Supplement 1) ◽  
pp. 4150-4150
Author(s):  
Sanjana Mullangi ◽  
Preeti Yadav ◽  
Ekim Kilinc ◽  
Silpa Gudivada ◽  
Javaria Khan ◽  
...  
Keyword(s):  
United States ◽  
Logistic Regression ◽  
Blood Cell ◽  
Hospital Mortality ◽  
Red Blood Cell ◽  
Autoimmune Hemolytic Anemia ◽  
The United States ◽  
Study Cohort ◽  
Factors Associated ◽  
Poor Outcomes

Abstract Introduction: Autoimmune hemolytic anemia (AIHA) is an acquired immune disorder resulting in the production of cold and warm autoantibodies directed against red blood cell antigens; characterized by shortened red blood cell survival and a positive Coombs test. Types include primary disease (idiopathic) or secondary to other autoimmune disorders, malignancies, or infections. Treatment involves immunosuppression with corticosteroids and other agents, Transfusion. There is not much recent data available on epidemiology of AIHA. We aim to estimate epidemiological trends and outcomes of AIHA as well as factors associated with poor outcomes by using the largest available national database from the United States. Methods: We derived a study cohort from the National Inpatient Sample (NIS) for the years 2007-2018 for hospitalizations due to AIHA by using International Classification of Diseases (9th/10th Editions) Clinical Modification diagnosis codes ICD-9-CM/ICD-10-CM). Other diagnosis and comorbidities were also identified by ICD-9/10-CM codes and Elixhauser comorbidity software. Our primary outcome was discharge disposition following AIHA hospitalization. We utilized multivariable survey logistic regression models to analyze and identify predictors of poor outcomes. Results: Between 2007-2018, a total of 52,814 hospitalizations occurred due to primary diagnosis of AIHA. Burden of hospitalizations remained stable from 4,254 (8.1%) in 2007 to 4,405 (8.3%) in 2018. AIHA patients in the study cohort were mostly above 65 years of age (48.6%) followed by 35-65 years of age (33.7%), females (58.3%) and Caucasians (69.1%). Overall in-hospital mortality of AIHA hospitalizations was 3.1%, and discharge to facility was 11.86%. Median length of stay for AIHA hospitalization was 4-days (interquartile range: 2-days to 6-days). Furthermore, in multivariable logistic regression analysis, increasing age (OR 1.2; 95%CI 1.1-1.3; p&lt;0.001), male gender (OR 1.5; 95%CI 1.2-1.3; p:0.0024), vascular events (OR 1.5 ; 95%CI 1.1-2.0; p:0.0156), teaching hospitals (OR 3.1; 95%CI 1.5-6.5; p:0.002), plasmapheresis (OR 5.5; 95%CI 2.8-10.8; p:0.001) and intravenous immunoglobulins (OR 1.9; 95%CI 1.3-3.0; p:0.001) were associated with higher in-hospital mortality. Conclusion: Our study describes the epidemiology of hospitalizations due to AIHA in the United States from a nationally representative database. We observed that hospitalization burden due to AIHA have remained stable from 2007 to 2018. We also identified factors associated with higher in-hospital mortality and some of which are modifiable. Further studies are required to establish the causal association of these factors to poor outcomes and develop better risk stratification strategies to improve overall outcomes of AIHA. Disclosures No relevant conflicts of interest to declare.

scholarly journals Covid-19 in Hospitalized Patients Admitted from Skilled Nursing Facilities: Factors Associated with Mortality

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 941-941
Author(s):  
Rongfang Zhan ◽  
Cheng Yin ◽  
Liam O'Neill
Keyword(s):  
Logistic Regression ◽  
Univariate Analysis ◽  
Survival Rates ◽  
Nursing Home Residents ◽  
Binary Logistic Regression ◽  
Hospitalized Patients ◽  
Skilled Nursing Facilities ◽  
Nursing Facilities ◽  
Skilled Nursing ◽  
Factors Associated

Abstract Background Nursing home residents were impacted disproportionately by the coronavirus because of their vulnerabilities. Although many studies concentrated on risk factors associated with mortality of hospitalized patients, there were limited studies epitomizing them from skilled nursing facilities to hospitals. The study aims to identify inpatients’ characteristics on demographics, hospital admission types, insurance types, and chronic diseases associated with mortality among our cohort patients in Texas. Methods Individuals above 50 years, diagnosed with Covid-19, and admitted from skilled nursing facilities were included in the retrospective cohort study. Pearson’s Chi-Square and Mann-Whitney tests were applied to measure four major perspectives between survivors and non-survivors. Then, a binary logistic regression was employed to determine the association between independent variables and mortality. Results A total of 218 patients were included in the study, of which 54 (24.8%) died during hospitalization. According to the univariate analysis, expired patients were more likely to be emergency admission (p = 0.001), elective admission (p = 0.02), Medicaid as primary payment (p = 0.034), heart disease (p = 0.027), CKD (p = 0.03), and hypertension (p = 0.002). The binary logistic regression revealed that hypertension (OR = 3.176, 95% CI: 1.200-8.409, p = 0.02) and Medicaid (OR = 2.637, 95% CI: 1.287-5.405, p = 0.008) as primary payment had significantly high odds of mortality. Conclusion Hypertension and Medicaid as primary payment are the strongest predictive factors associated with mortality and suggest that hospitals in Texas distribute critical care and resources while prevent and treat them to increase survival rates.

scholarly journals Risk factors associated with prolonged viral clearance in patients with a refractory course of COVID-19: a retrospective study

PeerJ ◽  
2021 ◽  
Vol 9 ◽  
pp. e12535
Author(s):  
Weitao Zhuang ◽  
Shujie Huang ◽  
Dongya Wang ◽  
Lulu Zha ◽  
Wei Xu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Multivariate Analysis ◽  
Serum Level ◽  
Univariate Analysis ◽  
High Serum ◽  
Viral Clearance ◽  
Study Cohort ◽  
Clinicopathologic Characteristics ◽  
Illness Onset ◽  
Factors Associated

Background This study aimed to characterize a cohort of patients with a refractory course of COVID-19, and to investigate factors associated with the duration of viral clearance (DoVC). Materials & Methods A total of 65 patients with refractory COVID-19 were retrospectively enrolled from Huoshenshan Hospital. Univariate analysis and multivariate analysis were performed to examine the potential association between clinicopathologic characteristics and the DoVC. Results The median DoVC in the overall study cohort was 48 days (ranged from 21 to 104 days). Multivariate analysis indicated that fever at illness onset (Hazard ratio (HR) = 4.897, 95% CI [1.809–13.260], p = 0.002), serum level of aspartate aminotransferase (AST) > 21.8 IU/L (HR = 3.010, 95% CI [1.195–7.578], p = 0.019), and titer of SARS-CoV-2 IgG > 142.09 AU/ml (HR = 3.061, 95% CI [1.263–7.415], p = 0.013) were the three independent risk factors associated with delayed viral clearance. Conclusion The current study suggested that clinical characteristics such as fever at illness onset, a high serum level of AST or SARS-CoV-2 IgG were associated with delayed viral clearance. Patients with these characteristics might need a more individualized treatment strategy to accelerate their recovery from the refractory COVID-19.

scholarly journals Serum Epidemiological Analysis and Risk Factors Associated with Leptospira spp. in Cattle in the State of Piauí

2017 ◽  
Vol 45 (1) ◽  
pp. 11
Author(s):  
Siluana Benvindo Ferreira ◽  
Katiene Régia Silva Sousa ◽  
Vanessa Castro ◽  
Sabrina Thabla Pereira Lopes ◽  
Sávio Benvindo Ferreira ◽  
...  
Keyword(s):  
Risk Factors ◽  
Logistic Regression ◽  
Regression Analysis ◽  
Logistic Regression Analysis ◽  
Statistical Significance ◽  
Univariate Analysis ◽  
Multivariate Logistic Regression Analysis ◽  
Control Measures ◽  
Factors Associated ◽  
Leptospira Spp

Background: Leptospirosis is a cosmopolitan zoonosis caused by pathogenic spirochetes of the genus Leptospira spp. and it is considered one of the main causes of reproductive problems in cattle. Therefore, the aim of this study was to determine the occurrence of anti-Leptospira antibodies and identify the prevalent serovars and risk factors associated with infection in cattle herds, in the microregion of Floriano, Piaui State, Brazil.Materials, Methods & Results: A total of 414 bovine sera samples were collected (390 females aged over 24 months and 24 bulls) from 22 properties (farms) in the municipalities that compose the study area. The samples were analyzed using the Microscopic Agglutination Test (MAT) to detect anti-Leptospira antibodies from 23 pathogenic serovars. An epidemiological questionnaire was applied in each farm to evaluate the risk factors, using a univariate analysis of the variables of interest, by Pearson’s Chi-square test (χ2) or Fisher’s exact test, when it was necessary. Then, each independent variable was crossed with the dependent variable and those that presented statistical significance <0.20 were selected for multivariate analysis, using logistic regression, adopting a significance level of 5%. This research identified 143 positive animals (MAT> 1: 100) in the 22 evaluated farms; all of them had at least one positive animal, resulting in a prevalence of 34.54%, with 32,8% females (136) and 1,7% males (07), and 8,93% (37) of co-agglutination. Nineteen of the 23 tested serovars were identified; among them, Icterohaemorrhagiae (42.48%), Hardjo (31.2%), Pomona (4.3%), and Castellonis (4.3%) stood out. Absence of quarantine (OR = 16.172, P = 0.024), vaccination (OR = 0.090, P = 0.037) and isolation of diseased animals (OR = 0.006, P = 0.030) were identified, by the multivariate logistic regression analysis, as risk factors for any serovar of Leptospira spp.Discussion: The results of the present study showed that leptospirosis is present in all studied municipalities, in which the prevalence may be related to the variety of factors that influence the occurrence of the disease, such as climatic and environmental conditions, transit of animal, practices of management adopted in the herd, and the lack of information about the disease. The occurrence of co-agglutination can be explained by the possibility of multiple and concomitant contaminations with several serovars. Icterohaemorrhagiae was the most prevalent serovar, which has significant importance to public health since it is considered the main serovar of leptospirosis in humans, associated with the presence of rodents. On the other hand, the serovar Hardjo is related to the chronic leptospirosis in cattle, demonstrated through reproductive problems. The serovars Castellonis and Pomona were also observed in bovine herds, suggesting a possible transmission of the microorganism between animal species, probably due to exposure to the same sources of infection. In fact, the large number of serovarieties of Leptospira spp. indicates the presence of one or more maintenance hosts, which are natural reservoirs of this infection. The risk factors confirmed in the logistic regression analysis probably occur due to failures in sanitary management. It is concluded that Leptospira spp. is disseminated in cattle in the studied region, with the presence of several serovars, which reinforces the need for intensifying the prevention and control measures, such as vaccination.

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