scholarly journals The Association Between Maternal Tibia Lead, Folate Intake, and MTHFR Genotype, and Child Birth Weight

Epidemiology ◽  
2007 ◽  
Vol 18 (Suppl) ◽  
pp. S153
Author(s):  
K Kordas ◽  
A Ettinger ◽  
M Tellez Rojo ◽  
M Hernandez Avila ◽  
H Lamadrid
Keyword(s):  
Birth Weight ◽  
Folate Intake ◽  
Child Birth ◽  
Mthfr Genotype

Prediction of Child Birth Weight Using Kernel Extreme Reservoir Machine and QPSO for Optimization

2021 ◽  
Vol 2 (3) ◽  
Author(s):  
Ghalib Ahmed Tahir ◽  
Tooba Samad ◽  
Liu Zongying ◽  
Sundus Abrar ◽  
Murtaza Ashraf ◽  
...  
Keyword(s):  
Birth Weight ◽  
Child Birth

scholarly journals Impact of determinants on nutritional status among children up to five years at tertiary care hospital, HIMS, Sitapur, Uttar Pradesh

2021 ◽  
Vol 8 (3) ◽  
pp. 1391
Author(s):  
Ravi Pachori ◽  
Jiratithigan Sillapasuwan
Keyword(s):  
Birth Weight ◽  
Child Health ◽  
Sample Size ◽  
Health Care Services ◽  
Tertiary Care ◽  
Healthy Children ◽  
Care Hospital ◽  
Cross Sectional ◽  
Child Birth ◽  
Mother’S Age

Background: Malnutrition in children occurs as a complex interplay among various factors like maternal health, dietary practices, hand washing and other hygiene practices, low birth weight, episode of diarrhoea and acute respiratory infection within the last 6 months are often associated with undernutrition in most developing nations including India. Objective of the study were to assess the determinants of maternal and child health, hygienic practice, health services for underweight and their association among apparently healthy children. Methods: The present study was hospital based descriptive cross-sectional study conducted from June 2019 to December 2019. The sample size calculated was 410, and accounting for 10% nonresponsive, the sample size calculated was 451. The data obtained were compiled and entered in MS-excel 2010 and analysed by using institutional SPSS (22.0). Results: Mother’s age at marriage <18 years belong to 68 (15.1%) children significantly low proportion as compared to marriage >18 years 383 (84.9%) including underweight 41 (22.5%) and mother’s age at child birth <18 years belong to 46 (10.2%) children significantly very low proportion in comparison to child birth >18 years including underweight 30 (16.6%). Birth weight <2.5 kg belongs to significantly 136 (30.1%) children including underweight 72 (39.8%) and significantly birth order >2 belong to 135 (29.9%) children including underweight 39 (21.6%). Exclusive breast feeding belongs to 149 (33.0%) children including underweight 62 (34.2%)Conclusions: Health education and its reinforcement especially in the area of maternal & child health care services is required.

scholarly journals A comparative analysis of determinants of low birth weight and stunting among under five children of adolescent and non-adolescent mothers using 2015/16 Tanzania Demographic and Health Survey (TDHS)

BMC Nutrition ◽  
2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Ramadhani H. Mtongwa ◽  
Charles Festo ◽  
Ester Elisaria
Keyword(s):  
Socioeconomic Status ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Adolescent Mothers ◽  
Maternal Age ◽  
Maternal Obesity ◽  
Maternal Body Mass Index ◽  
Child Birth ◽  
Maternal Undernutrition ◽  
Children Under 5

Abstract Background Tanzania is one of the Sub-Saharan African country with nearly 12 out of 60 million people being adolescent. The prevalence of child marriage is higher with one out of every three girls being married before reaching their 18th birthday, 5 % being married by the age of 15, and 31% by the age of 18 years. Literature shows early pregnancy is associated with Low Birth Weight (LBW) and stunting among children under 5 years. This paper explores variation and factors associated with low birth weight and stunting among children born by adolescent and non-adolescent mothers. Methods Data from 13,266 women with children under 5 years collected as part of the 2015/2016 TDHS was re-analyzed using STATA version 14 software while accounting for survey design. A total of 6385 women (of which 7.2% were adolescent) and 8852 women (of which 6.7% were adolescent) were involved in the analysis of child birth weight and stunting respectively. Descriptive statistics stratified by maternal age was conducted with LBW and stunting as outcome variables followed by logistic regressions models controlling for confounding variables. Results The proportion of obese or overweight adolescent and non-adolescent mothers was 11.8 and 36.5% respectively. Antenatal care (ANC) attendance, areas of residence and social economic status were very similar in the two maternal age groups. Non- adolescent mothers had reduced odds of giving birth to LBW babies compared to adolescent mothers (Adjusted Odds Ratio (AOR) = 0.34; 95% CI: 0.22–0.50). Maternal undernutrition (AOR = 2.29; 95% CI: 1.43–3.67), being divorced, separated or widowed (AOR = 1.76; 95% CI: 1.24–2.50) and having at least four ANC visits (AOR = 0.64; 95% CI: 0.49–0.83) were significantly associated with reduced odds of having a LBW. Child stunting was not associated with maternal age. Maternal high socioeconomic status (AOR = 0.69; 95% CI: 0.57–0.84) and maternal obesity or overweight (AOR = 0.77; 95% CI: 0.64–0.92) were negatively associated with stunting. Child birth weight, sex, and age were significantly associated with stunting. Conclusion Maternal age was a predictor of LBW but not stunting. ANC attendance and not living with a spouse increase the risk of LBW babies. Stunting was associated with low maternal body mass index (BMI), low socioeconomic status, child birth weight, gender, and age. A multi-sectoral approach is needed to address child nutrition problems with teenagers ‘specific intervention that offer emotional support, and health education during pregnancies for improving immediate and later life child birth outcomes.

scholarly journals Maternal education and offspring birth weight for gestational age: the mediating effect of smoking during pregnancy

2020 ◽  
Vol 30 (5) ◽  
pp. 1001-1006 ◽  
Author(s):  
Aurélie Nakamura ◽  
Laura Pryor ◽  
Morgane Ballon ◽  
Sandrine Lioret ◽  
Barbara Heude ◽  
...  
Keyword(s):  
Birth Weight ◽  
Educational Attainment ◽  
Gestational Age ◽  
Tobacco Smoking ◽  
Mediation Analysis ◽  
Maternal Smoking ◽  
Maternal Education ◽  
Mediating Effect ◽  
Smoking During Pregnancy ◽  
Child Birth

Abstract Background Small for gestational age (SGA) birth weight, a risk factor for infant mortality and delayed child development, is associated with maternal educational attainment. Maternal tobacco smoking during pregnancy could contribute to this association. We aimed to quantify the contribution of maternal smoking during pregnancy to social inequalities in child birth weight for gestational age (GA). Methods Data come from the French nation-wide ELFE cohort study, which included 17 155 singletons. Birth weights for GA were calculated using z-scores. Associations between maternal educational attainment, tobacco smoking during pregnancy and child birth weight for GA were ascertained using mediation analysis. Mediation analyses were also stratified by maternal pre-pregnancy body mass index. Results Low maternal educational attainment was associated with an increased odd of tobacco smoking during pregnancy [adjusted OR (ORa) = 2.58 (95% CI 2.34–2.84)] as well as a decrease in child birth weight for GA [RRa = 0.94 (95% CI 0.91–0.98)]. Tobacco smoking during pregnancy was associated with a decrease in offspring birth weight for GA [RRa = 0.73 (95% CI 0.70–0.76)]. Mediation analysis suggests that 39% of the effect of low maternal educational attainment on offspring birth weight for GA was mediated by smoking during pregnancy. A more important direct effect of maternal educational attainment on child birth weight for GA was observed among underweight women [RRa = 0.82 (95% CI 0.72–0.93)]. Conclusions The relationship between maternal educational attainment and child birth weight for GA is strongly mediated by smoking during pregnancy. Reducing maternal smoking could lessen the occurrence of infant SGA and decrease socioeconomic inequalities in birth weight for GA.

scholarly journals Passive rGE or Developmental Gene-Environment Cascade? An Investigation of the Role of Xenobiotic Metabolism Genes in the Association Between Smoke Exposure During Pregnancy and Child Birth Weight

2016 ◽  
Vol 46 (3) ◽  
pp. 365-377 ◽  
Author(s):  
Kristine Marceau ◽  
Rohan H. C. Palmer ◽  
Jenae M. Neiderhiser ◽  
Taylor F. Smith ◽  
John E. McGeary ◽  
...  
Keyword(s):  
Birth Weight ◽  
Xenobiotic Metabolism ◽  
Smoke Exposure ◽  
Developmental Gene ◽  
Child Birth ◽  
Gene Environment ◽  
Exposure During Pregnancy

scholarly journals Early life factors and their relevance to intima-media thickness of the common carotid artery in early adulthood

2020 ◽  
Vol 79 (OCE2) ◽  
Author(s):  
Juliana Nyasordzi ◽  
Katharina Penczynski ◽  
Thomas Remer ◽  
Anette Buyken
Keyword(s):  
Birth Weight ◽  
Carotid Artery ◽  
Young Adulthood ◽  
Early Life ◽  
Maternal Age ◽  
Early Adulthood ◽  
Intima Media Thickness ◽  
Paternal Age ◽  
Child Birth ◽  
Early Life Factors

AbstractIntroductionEarly life factors may predispose an offspring to cardiovascular risk factors in later life. It is plausible a range of exposures in early life may be involved in this predisposition, which may extend to “healthy” populations in Western populations.We examined the association between a number of early life factors with the carotid intima-media thickness (IMT), a surrogate marker of atherosclerosis, in early adulthood of a healthy German population.MethodsWe studied term participants (n = 265) of the DONALD Study, with a bilateral sonographic measurement of the IMT in young adulthood (18–40 years) and data on early life factors (maternal and paternal age at child birth, birth weight (including appropriateness of birth weight- for gestational age), gestational weight gain and full breastfeeding (breastfeeding > 17weeks). Sonographic IMT measurements were performed on the left and right common carotid artery using a minimum of 4 measurements. Mean IMT values were obtained averaging the measurements from both sides, an overall average obtained from 8 and 16 measurement of both sides was used for this analysis. Information on gestation and birth were abstracted from the “Mutterpass”, maternal and paternal age at birth were inquired at study entry and breastfeeding information was assessed prospectively. Prospective association between early life factors and IMT were analyzed using multivariable linear regression models, considering age at IMT measurement, physician taking the measurement, in addition: birth year, first born status, maternal and paternal educational status, maternal overweight, presence of smokers in the household tested for potential confounding.ResultsMean adult IMT was 0.56mm ± 0.03, range: 0.41mm-0.78 mm. Maternal age at child birth was of prospective relevance for IMT in young adulthood, however, this association was sex specific: Increased maternal age at child birth was independently associated with an increased IMT among female offspring during young adulthood (β 0.029, SE 0.009) mm/decade, P = 0.003) only, this was not mediated by adult waist circumference. None of the remaining early life factors showed relevance for adult IMT levels among males and females in early adulthood.ConclusionThis study suggests that advanced maternal age at child birth is of prospective relevance for IMT levels in younger adulthood in a healthy Western population. This association appears to be sex specific, with maternal age at child birth positively associated with IMT in females in early adulthood only.

Exposure to biomass fuel and low child birth weight – Findings of Pakistan Demographic and Health Survey 2006–2007

2015 ◽  
Vol 3 (5) ◽  
pp. 19 ◽  
Author(s):  
Mubashir Zafar ◽  
Zeeshan Ahmed ◽  
NaveedAli Khan ◽  
MuhammadSameer Qureshi
Keyword(s):  
Birth Weight ◽  
Health Survey ◽  
Demographic And Health Survey ◽  
Biomass Fuel ◽  
Child Birth

scholarly journals Methylenetetrahydrofolate reductase (MTHFR) C677T, A1298C and G1793A genotypes, and the relationship between maternal folate intake, tibia lead and infant size at birth

2009 ◽  
Vol 102 (6) ◽  
pp. 907-914 ◽  
Author(s):  
Katarzyna Kordas ◽  
Adrienne S. Ettinger ◽  
Héctor Lamadrid-Figueroa ◽  
Martha M. Tellez-Rojo ◽  
Mauricio Hérnandez-Avila ◽  
...  
Keyword(s):  
Birth Weight ◽  
Methylenetetrahydrofolate Reductase ◽  
Maternal Nutrition ◽  
Explanatory Models ◽  
Folate Intake ◽  
Birth Size ◽  
Term Infants ◽  
Pb Exposure ◽  
The Relationship ◽  
Size At Birth

Small size at birth continues to be a problem worldwide and many factors, including reduced folate intake and Pb exposure, are associated with it. However, single factors rarely explain the variability in birth weight, suggesting a need for more complex explanatory models. We investigated environment–gene interactions to understand whether folate intake and maternal Pb exposure were associated with smaller newborn size in 474 women with uncomplicated pregnancies delivering term infants in Mexico City. We examined if folate intake modified the negative effects of maternal Pb burden on birth size. We also asked if maternal and infant methylenetetrahydrofolate reductase (MTHFR) genotypes (C677T, A1298C and G1793A) modified the effects of folate intake or Pb exposure on birth size. Women were aged 24·6 (sd 5·1) years; 43·5 % were primiparous. Maternal blood Pb at delivery was 86 (sd 42) μg/l, with 26·7 % having levels ≥ 100 μg/l. Tibia Pb level was 9·9 (sd 9·8) μg/g. Of the women, 35·3 % had folate intakes < 400 μg/d. Birth weight was 3170 (sd 422) g. In covariate-adjusted regressions, higher folate intake was associated with higher birth weight (β 0·04; P < 0·05). Higher bone Pb was associated with lower birth weight (β − 4·9; P < 0·05). Folate intake did not modify the effects of Pb on birth size, nor did MTHFR modify the association between Pb or folate intake on birth size. Although modest, the relationship between maternal nutrition, Pb burden and birth size does underscore the importance of environmental exposures to child health because patterns of fetal growth may affect health outcomes well into adulthood.

Effect of Prenatal Care Frequency, Timing, and Quality on Child Birth Weight in Tajikistan

2017 ◽  
Vol 9 (1) ◽  
pp. 89-102 ◽  
Author(s):  
Nazim Habibov ◽  
Lida Fan ◽  
Derek Campbell ◽  
Chi Ho Cheung
Keyword(s):  
Birth Weight ◽  
Prenatal Care ◽  
Child Birth

Association of Prepregnancy BMI, Gestational Weight Gain, and Child Birth Weight with Metabolic Dysfunction in Children and Adolescents with Obesity

2020 ◽  
Vol 113 (10) ◽  
pp. 482-487
Author(s):  
Kelsey Pearson ◽  
Kristine C. Jordan ◽  
Julie Metos ◽  
Richard Holubkov ◽  
M. Nazeem Nanjee ◽  
...  
Keyword(s):  
Weight Gain ◽  
Birth Weight ◽  
Children And Adolescents ◽  
Gestational Weight Gain ◽  
Metabolic Dysfunction ◽  
Child Birth ◽  
Gestational Weight ◽  
Prepregnancy Bmi
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