Heparin-induced Thrombocytopenia: Perioperative Diagnosis and Management

2021 ◽  
Author(s):  
Andreas Koster ◽  
Michael Nagler ◽  
Gabor Erdoes ◽  
Jerrold H. Levy
Keyword(s):  
Diagnosis And Treatment ◽  
Heparin Induced Thrombocytopenia ◽  
Diagnostic Algorithms ◽  
Diagnosis And Management ◽  
Timely Diagnosis ◽  
Clinical Scoring ◽  
Scoring Tools

Heparin-induced thrombocytopenia is a severe prothrombotic disease. Timely diagnosis and treatment are essential. Application of diagnostic algorithms based on validated clinical scoring tools and rapid, specific laboratory assays may improve outcomes.

Diagnosis and Management of Hemispheric Infarction

2019 ◽  
pp. 543-546
Author(s):  
Sanjeet S. Grewal ◽  
Benjamin L. Brown
Keyword(s):  
Acute Stroke ◽  
Diagnosis And Treatment ◽  
Management Options ◽  
Diagnosis And Management ◽  
Risks And Benefits ◽  
Timely Diagnosis ◽  
Hemispheric Infarction ◽  
Meaningful Communication

Hemispheric infarction is a major cause of morbidity and death among patients with acute stroke. These patients must receive a timely diagnosis and treatment for the best outcomes. Treatment is often multimodal and requires close and meaningful communication with the patient and family about management options and the risks and benefits of each.

scholarly journals Heparin-induced thrombocytopenia (HIT): Review of incidence, diagnosis, and management

2020 ◽  
Vol 25 (2) ◽  
pp. 160-173 ◽  
Author(s):  
Marie Hogan ◽  
Jeffrey S Berger
Keyword(s):  
Laboratory Testing ◽  
Clinical Suspicion ◽  
High Index ◽  
Heparin Induced Thrombocytopenia ◽  
Diagnosis And Management ◽  
Alternative Anticoagulation ◽  
Clinical Scoring ◽  
Rule Out ◽  
Heparin Exposure

Heparin-induced thrombocytopenia (HIT) is a life and limb-threatening complication of heparin exposure. Here, we review the pathogenesis, incidence, diagnosis, and management of HIT. The first step in thwarting devastating complications from this entity is to maintain a high index of clinical suspicion, followed by an accurate clinical scoring assessment using the 4Ts. Next, appropriate stepwise laboratory testing must be undertaken in order to rule out HIT or establish the diagnosis. In the interim, all heparin must be stopped immediately, and the patient administered alternative anticoagulation. Here we review alternative anticoagulation choice, therapy alternatives in the difficult-to-manage patient with HIT, and the problem of overdiagnosis.

Comparison of Clinical Scoring Tools to Predict Heparin-Induced Thrombocytopenia in Cardiac Surgery

2021 ◽  
Author(s):  
Kari A. Allan ◽  
Jessica R. Crow ◽  
Jessica E. Chasler ◽  
Janhavi Athale ◽  
John P. Lindsley ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Heparin Induced Thrombocytopenia ◽  
Clinical Scoring ◽  
Scoring Tools

Diagnosis and Management of Vaccine-Related Thrombosis following AstraZeneca COVID-19 Vaccination: Guidance Statement from the GTH

2021 ◽  
Author(s):  
Johannes Oldenburg ◽  
Robert Klamroth ◽  
Florian Langer ◽  
Manuela Albisetti ◽  
Charis von Auer ◽  
...  
Keyword(s):  
Immune Thrombocytopenia ◽  
Rare Complication ◽  
Diagnosis And Treatment ◽  
Heparin Induced Thrombocytopenia ◽  
Diagnosis And Management ◽  
Healthcare Crisis

AbstractThe COVID-19 pandemic is an ongoing global healthcare crisis. Based on reports of atypically located thromboses following vaccination with the AstraZeneca COVID-19 vaccine, the Society of Thrombosis and Haemostasis Research (GTH) has issued guidance statements on the recognition, diagnosis, and treatment of this rare complication. It shares pathophysiological features with heparin-induced thrombocytopenia (HIT) and is referred to as vaccine-induced prothrombotic immune thrombocytopenia (VIPIT).

Orthodontic management of impacted mandibular second molars: A case series

2021 ◽  
Vol 14 (2) ◽  
pp. 98-104
Author(s):  
Andrea Cunningham ◽  
Dipali Patel ◽  
Zahra Sheriteh
Keyword(s):  
Early Diagnosis ◽  
Clinical Relevance ◽  
Case Series ◽  
Diagnosis And Treatment ◽  
Treatment Modalities ◽  
Individual Basis ◽  
Diagnosis And Management

This case series describes a number of different treatment modalities used in the management of impacted mandibular second molars (MM2s). A variety of cases is used to illustrate a number of ways in which these teeth can be managed, and to demonstrate that each case should be managed on an individual basis, taking into account the overall malocclusion. The importance of early diagnosis and management is highlighted throughout. CPD/Clinical Relevance: This case series highlights the difficulties and challenges in managing patients who present with impacted lower second molars (MM2s), and the importance of early diagnosis and treatment.

scholarly journals Testicular dislocation: the importance of scrotal examination in a trauma patient

2012 ◽  
Vol 94 (2) ◽  
pp. e109-e110 ◽  
Author(s):  
A Naseer ◽  
D King ◽  
H Lee ◽  
J Vale
Keyword(s):  
Trauma Patient ◽  
Surgical Management ◽  
Rare Event ◽  
Perineal Trauma ◽  
Diagnosis And Treatment ◽  
Careful Examination ◽  
Timely Diagnosis ◽  
Appropriate Treatment ◽  
Testicular Dislocation

Testicular dislocation after blunt perineal trauma is a rare event and a diagnosis that can be easily overlooked. Careful examination can help facilitate early and appropriate treatment. Timely diagnosis and surgical management are of paramount importance to preserve normal spermatogenic function in the dislocated testicle. We describe a case of testicular dislocation and discuss some of the issues surrounding diagnosis and treatment.

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