Sorafenib, but not sunitinib, induces regulatory T cells in the peripheral blood of patients with metastatic renal cell carcinoma

Anne Flörcken; Anna Takvorian; Antje Van Lessen; Anju Singh; Werner Hopfenmüller; Bernd Dörken; Antonio Pezzutto; Jörg Westermann

doi:10.1097/cad.0b013e32834ee2b1

Sorafenib, but not sunitinib, induces regulatory T cells in the peripheral blood of patients with metastatic renal cell carcinoma

Anti-Cancer Drugs ◽

10.1097/cad.0b013e32834ee2b1 ◽

2012 ◽

Vol 23 (3) ◽

pp. 298-302 ◽

Cited By ~ 14

Author(s):

Anne Flörcken ◽

Anna Takvorian ◽

Antje Van Lessen ◽

Anju Singh ◽

Werner Hopfenmüller ◽

...

Keyword(s):

Renal Cell Carcinoma ◽

T Cells ◽

Regulatory T Cells ◽

Cell Carcinoma ◽

Metastatic Renal Cell Carcinoma ◽

Peripheral Blood ◽

Renal Cell

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Increase of CD4+CD25highFoxp3+ regulatory T cells in peripheral blood in patients with metastatic renal cell carcinoma treated with dendritic cell vaccination and low-dose IL-2

Journal of Clinical Oncology ◽

10.1200/jco.2008.26.15_suppl.16144 ◽

2008 ◽

Vol 26 (15_suppl) ◽

pp. 16144-16144

Author(s):

A. Berntsen ◽

M. K. Brimnes ◽

P. T. Straten ◽

I. M. Svane

Keyword(s):

Renal Cell Carcinoma ◽

T Cells ◽

Dendritic Cell ◽

Regulatory T Cells ◽

Cell Carcinoma ◽

Metastatic Renal Cell Carcinoma ◽

Peripheral Blood ◽

Renal Cell ◽

Low Dose ◽

Dendritic Cell Vaccination

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Regulatory T-Cells and Associated Pathways in Metastatic Renal Cell Carcinoma (mRCC) Patients Undergoing DC-Vaccination and Cytokine-Therapy

PLoS ONE ◽

10.1371/journal.pone.0046600 ◽

2012 ◽

Vol 7 (10) ◽

pp. e46600 ◽

Cited By ~ 13

Author(s):

Adrian Schwarzer ◽

Benita Wolf ◽

Jan L. Fisher ◽

Thomas Schwaab ◽

Sven Olek ◽

...

Keyword(s):

Renal Cell Carcinoma ◽

T Cells ◽

Regulatory T Cells ◽

Cell Carcinoma ◽

Metastatic Renal Cell Carcinoma ◽

Renal Cell ◽

Cytokine Therapy

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Increase of Circulating CD4+CD25highFoxp3+ Regulatory T Cells in Patients With Metastatic Renal Cell Carcinoma During Treatment With Dendritic Cell Vaccination and Low-Dose Interleukin-2

Journal of Immunotherapy ◽

10.1097/cji.0b013e3181cd870f ◽

2010 ◽

Vol 33 (4) ◽

pp. 425-434 ◽

Cited By ~ 26

Author(s):

Annika Berntsen ◽

Marie Klinge Brimnes ◽

Per thor Straten ◽

Inge Marie Svane

Keyword(s):

Renal Cell Carcinoma ◽

T Cells ◽

Dendritic Cell ◽

Regulatory T Cells ◽

Cell Carcinoma ◽

Metastatic Renal Cell Carcinoma ◽

Renal Cell ◽

Low Dose ◽

Interleukin 2 ◽

Dendritic Cell Vaccination

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High Immune Response Rates and Decreased Frequencies of Regulatory T Cells in Metastatic Renal Cell Carcinoma Patients after Tumor Cell Vaccination

Molecular Medicine ◽

10.2119/molmed.2012.00221 ◽

2012 ◽

Vol 18 (12) ◽

pp. 1499-1508 ◽

Cited By ~ 12

Author(s):

Heike Pohla ◽

Alexander Buchner ◽

Birgit Stadlbauer ◽

Bernhard Frankenberger ◽

Stefan Stevanovic ◽

...

Keyword(s):

Renal Cell Carcinoma ◽

Immune Response ◽

T Cells ◽

Regulatory T Cells ◽

Tumor Cell ◽

Cell Carcinoma ◽

Metastatic Renal Cell Carcinoma ◽

Renal Cell ◽

Response Rates

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REGULATORY T CELLS EXPRESSION IN PERIPHERAL BLOOD AND TUMOUR INFILTRATE OF PATIENTS WITH RENAL CELL CARCINOMA: CORRELATION WITH PROGNOSTIC FACTORS

European Urology Supplements ◽

10.1016/s1569-9056(08)60114-1 ◽

2008 ◽

Vol 7 (3) ◽

pp. 99 ◽

Cited By ~ 1

Author(s):

M. Gacci ◽

S. Serni ◽

A. Lapini ◽

D. Moreno Mendoza ◽

N. Tosi ◽

...

Keyword(s):

Renal Cell Carcinoma ◽

T Cells ◽

Prognostic Factors ◽

Regulatory T Cells ◽

Cell Carcinoma ◽

Peripheral Blood ◽

Renal Cell

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F.134. Increased Population of CD4+CD25high Regulatory T-Cells in the Peripheral Blood of Renal Cell Carcinoma Patients

Clinical Immunology ◽

10.1016/j.clim.2006.04.174 ◽

2006 ◽

Vol 119 ◽

pp. S98

Author(s):

Eyad Elkord ◽

Richard Griffiths ◽

Dominic Rothwell ◽

David Gilham ◽

Peter Stern ◽

...

Keyword(s):

Renal Cell Carcinoma ◽

T Cells ◽

Regulatory T Cells ◽

Cell Carcinoma ◽

Peripheral Blood ◽

Renal Cell

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Frequency of regulatory T cells in peripheral blood and in tumour-infiltrating lymphocytes correlates with poor prognosis in renal cell carcinoma

BJU International ◽

10.1111/j.1464-410x.2010.09555.x ◽

2010 ◽

Vol 107 (9) ◽

pp. 1500-1506 ◽

Cited By ~ 66

Author(s):

Francesco Liotta ◽

Mauro Gacci ◽

Francesca Frosali ◽

Valentina Querci ◽

Gianni Vittori ◽

...

Keyword(s):

Renal Cell Carcinoma ◽

T Cells ◽

Regulatory T Cells ◽

Cell Carcinoma ◽

Peripheral Blood ◽

Renal Cell ◽

Poor Prognosis ◽

Tumour Infiltrating Lymphocytes ◽

Infiltrating Lymphocytes

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PD57-08 TUMORAL CD8+ T CELLS CORRELATE WITH FAVORABLE OUTCOME IN METASTATIC RENAL CELL CARCINOMA TREATED WITH TYROSINE KINASE INHIBITORS

The Journal of Urology ◽

10.1016/j.juro.2018.02.2652 ◽

2018 ◽

Vol 199 (4S) ◽

Author(s):

Jiajun Wang ◽

Li Liu ◽

Wei Xi ◽

Jiejie Xu ◽

Jianming Guo

Keyword(s):

Renal Cell Carcinoma ◽

T Cells ◽

Tyrosine Kinase ◽

Cell Carcinoma ◽

Tyrosine Kinase Inhibitors ◽

Metastatic Renal Cell Carcinoma ◽

Cd8 T Cells ◽

Renal Cell ◽

Kinase Inhibitors ◽

Favorable Outcome

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Clinical and kinomic analysis identifies peripheral blood mononuclear cells as a potential pharmacodynamic biomarker in metastatic renal cell carcinoma patients treated with sunitinib

Oncotarget ◽

10.18632/oncotarget.11686 ◽

2016 ◽

Vol 7 (41) ◽

pp. 67507-67520 ◽

Cited By ~ 10

Author(s):

Gaёlle Noé ◽

Audrey Bellesoeur ◽

Audrey Thomas-Schoemann ◽

Savithri Rangarajan ◽

Faris Naji ◽

...

Keyword(s):

Renal Cell Carcinoma ◽

Cell Carcinoma ◽

Metastatic Renal Cell Carcinoma ◽

Peripheral Blood Mononuclear Cells ◽

Peripheral Blood ◽

Renal Cell ◽

Mononuclear Cells ◽

Peripheral Blood Mononuclear ◽

Blood Mononuclear Cells

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Infiltration of M2 Macrophages and Regulatory T Cells Plays a Role in Recurrence of Renal Cell Carcinoma

European Urology Open Science ◽

10.1016/j.euros.2020.06.003 ◽

2020 ◽

Vol 20 ◽

pp. 62-71

Author(s):

Sabina Davidsson ◽

Michelangelo Fiorentino ◽

Francesca Giunchi ◽

Margareta Eriksson ◽

Ann Erlandsson ◽

...

Keyword(s):

Renal Cell Carcinoma ◽

T Cells ◽

Regulatory T Cells ◽

Cell Carcinoma ◽

Renal Cell ◽

M2 Macrophages

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