scholarly journals Duration of Antibiotic Therapy in Neonatal Gram-negative Bacterial Sepsis—10 Days versus 14 Days

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Anurag Fursule ◽  
Anup Thakur ◽  
Pankaj Garg ◽  
Neelam Kler
PEDIATRICS ◽  
1968 ◽  
Vol 42 (5) ◽  
pp. 840-843
Author(s):  
Catherine M. Katz ◽  
Samuel L. Katz

A retrospective study of 280 nephrotic admissions from 1963 through 1967 at Children's Hospital Medical Center in Boston revealed that gram-negative bacilli have caused the majority of infections in hospitalized nephrotic children. The organisms isolated during this period included pneumococci, E. coli, proteus, klebsiella-enterobacter species, pseudomonas, and Serratia marcescens. This information is recorded to aid physicians in the selection of initial antibiotic therapy in the septic nephrotic patient.


2015 ◽  
Vol 14 (5) ◽  
pp. 523-529 ◽  
Author(s):  
Yi-Nan Jiang ◽  
Xun Cai ◽  
Hong-Min Zhou ◽  
Wei-Dong Jin ◽  
Min Zhang ◽  
...  

Author(s):  
Nindy Handayani ◽  
Soroy Lardo ◽  
Nunuk Nugrohowati

Introduction: Procalcitonin is known as a marker of infection and indicator for severity of infections. In sepsis, elevated procalcitonin levels in blood have a significant value that can be used as a sepsis biomarker. The aim of this study was to determine the mean difference of procalcitonin levels in Gram-positive and Gram-negative bacterial sepsis patients.Methods: This study used quantitative method with cross sectional approach. The sample of this study were bacterial sepsis patients of Indonesia Army Central Hospital Gatot Soebroto in 2016 which were divided into two groups: Gram-positive and Gram-negative bacterial sepsis patients with the number of each group was 30 samples. The data were analyzed by using independent t test.Results: This study showed that mean levels of procalcitonin in Gram-positive bacterial sepsis patients was 6.47 ng/ml and Gram-negative was 66.04 ng/ml. There was a significant difference between mean levels of procalcitonin in Gram-positive and Gram-negative bacterial sepsis patients of Indonesia Army Central Hospital Gatot Soebroto in 2016 with p value = 0.000 (p < 0.05).Conclusion: The mean difference of procalcitonin levels in Gram-negative bacterial sepsis patients were higher than Gram-positive bacterial sepsis patients, because Gram-negative bacteria have lipopolysaccharide which is a strong immunostimulator and increases TNF-α production higher than Gram-positive bacteria. 


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