Continuous Scale Physical Functional Performance Test: Appropriateness for Middle-Aged Adults With and Without Parkinson’s Disease

2007 ◽  
Vol 31 (2) ◽  
pp. 64-70 ◽  
Author(s):  
Thomas M. Hearty ◽  
Margaret L. Schenkman ◽  
Wendy M. Kohrt ◽  
M Elaine Cress
2006 ◽  
Vol 86 (11) ◽  
pp. 1479-1488 ◽  
Author(s):  
Lynn B Panton ◽  
J Derek Kingsley ◽  
Tonya Toole ◽  
M Elaine Cress ◽  
George Abboud ◽  
...  

Abstract Background and Purposes. The purpose of this study was to compare functionality and strength among women with fibromyalgia (FM), women without FM, and older women. Subjects. Twenty-nine women with FM (age [X̅±SD]=46±7 years), 12 age- and weight-matched women without FM (age=44±8 years), and 38 older women who were healthy (age=71±7 years) participated. Methods. The Continuous Scale–Physical Functional Performance Test (CS-PFP) was used to assess functionality. Isokinetic leg strength was measured at 60°/s, and handgrip strength was measured using a handgrip dynamometer. Results. The women without FM had significantly higher functionality scores compared with women with FM and older women. There were no differences in functionality between women with FM and older women. Strength measures for the leg were higher in women without FM compared with women with FM and older women, and both women with and without FM had higher grip strengths compared with older women. Discussion and Conclusion. This study demonstrated that women with FM and older women who are healthy have similar lower-body strength and functionality, potentially enhancing the risk for premature age-associated disability.


2002 ◽  
Vol 92 (2) ◽  
pp. 672-678 ◽  
Author(s):  
Martin Brochu ◽  
Patrick Savage ◽  
Melinda Lee ◽  
Justine Dee ◽  
M. Elaine Cress ◽  
...  

We studied whether disabled older women with coronary heart disease can perform resistance training at an intensity sufficient to improve measured and self-reported physical function [ n = 30, 70.6 ± 4.5 (SD) yr]. Compared with the controls, the resistance-training group showed significant improvements in overall measured physical function score using the Continuous-Scale Physical Functional Performance Test (+24 vs. +3%). The Continuous-Scale Physical Functional Performance Test measures physical function for 15 practical activities, such as carrying groceries or climbing stairs. Resistance training led to improved measures for domains of upper body strength (+18 vs. +6%), lower body strength (+23 vs. +6%), endurance (+26 vs. +1%), balance and coordination (+29 vs. −2%), and 6-min walk (+15 vs. +7%). Women involved in the flexibility-control group showed essentially no improvement for physical function measures. No changes were observed for body composition, aerobic capacity, or self-reported physical function in either group. In conclusion, disabled older women with coronary heart disease who participate in strength training are able to train at an intensity sufficient to result in improvements in multiple domains of measured physical functional performance, despite no change in lean body mass.


2009 ◽  
Vol 90 (3) ◽  
pp. 488-493 ◽  
Author(s):  
Patricia J. Manns ◽  
Corey R. Tomczak ◽  
Anwar Jelani ◽  
M. Elaine Cress ◽  
Robert Haennel

2005 ◽  
Vol 85 (4) ◽  
pp. 323-335 ◽  
Author(s):  
M Elaine Cress ◽  
John K Petrella ◽  
Trudy L Moore ◽  
Margaret L Schenkman

Abstract Background and Purpose. The Continuous-Scale Physical Functional Performance Test (CS-PFP) can be used to obtain valid, reliable, and sensitive measurements of physical functional capacity. This test requires a fixed laboratory space and approximately 1 hour to administer. This study was carried out in 4 steps, or substudies, to develop and validate a short, community-based version (PFP-10) that requires less space and equipment than the CS-PFP. Subjects and Methods. Retrospective data (n=228) and prospective data (n=91) on men and women performing the CS-PFP or the PFP-10 are reported. A 12-week exercise program was used to examine sensitivity to change. Data analyses were done using paired t-test, Pearson correlation, intraclass correlation coefficient (ICC), and delta index (DI) procedures. Results. The PFP-10 total score and 4 of the 5 domain scores were statistically similar (within 3%) to those of the CS-PFP. The PFP-10 upper-body strength domain score was 17% lower, but was highly correlated (ICC=.97). Community and established laboratory PFP-10 scores were similar (ICC=.85–.97). The PFP-10 also is sensitive to change (DI=.21–.54). Discussion and Conclusion. The PFP-10 yields valid, reliable, and sensitive measurements and can be confidently substituted for the CS-PFP.


2002 ◽  
Vol 26 (3) ◽  
pp. 130-138 ◽  
Author(s):  
Margaret Schenkman ◽  
Toni M. Cutson ◽  
Maggie Kuchibhatla ◽  
Burton L. Scott ◽  
Elaine M. Cress

2021 ◽  
Vol 2021 ◽  
pp. 1-11
Author(s):  
Sicong Li ◽  
Xu Sun ◽  
Lei Bi ◽  
Yujia Tong ◽  
Xin Liu

Parkinson’s disease (PD) is a common neurodegenerative disease in middle-aged and older adults. Abnormal proteins such as α-synuclein are essential factors in PD’s pathogenesis. Autophagy is the main participant in the clearance of abnormal proteins. The overactive or low function of autophagy leads to autophagy stress. Not only is it difficult to clear abnormal proteins but also it can cause damage to neurons. In this article, the effects of natural products ingredients, such as salidroside, paeoniflorin, curcumin, resveratrol, corynoxine, and baicalein, on regulating autophagy and protecting neurons were discussed in detail to provide a reference for the research and development of drugs for the treatment of PD.


2020 ◽  
Vol 28 ◽  
pp. S399-S400
Author(s):  
A. Castilho de Almeida ◽  
J. Aily ◽  
M. Pedroso ◽  
J. Rissi Bergamaschi ◽  
G. de Carvalho Silva ◽  
...  

Open Medicine ◽  
2016 ◽  
Vol 11 (1) ◽  
pp. 16-20 ◽  
Author(s):  
Hasan Toktas ◽  
Umit Dundar ◽  
Özge Yilmaz Kusbeci ◽  
Alper Murat Ulasli ◽  
Ozgur Toy ◽  
...  

AbstractIntroductionIn Parkinson’s disease (PD), a resting tremor of the thumb may affect the flexor pollicis longus (FPL) and influence hand functions. We investigated the relationship between FPL tendon thickness and hand function in PD patients and compared these characteristics with those in healthy controls.MethodsThe hand grip and pinch strengths were measured. The participants completed the Duruöz hand index, the Sollerman’s hand function test, and the Nine Hole Peg Test. The thickness of the FPL tendon was measured using ultrasonographyResultsThe FPL tendon was thicker in PD patients but was not associated with tremor severity. In PD patients, despite functional performance of the hands are impaired and grip strength is decreased, pinch strengths are preserved. FPL thickness was not correlated with grip and pinch strengths.ConclusionThe thicker FPL tendon may be associated with greater pinch and grip strengths and manual dexterity in healthy individuals. The presence of tremor is associated with a thicker FPL tendon.


2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Kadri Medijainen ◽  
Mati Pääsuke ◽  
Aet Lukmann ◽  
Pille Taba

Background. Neurological assessment of a patient with Parkinson’s disease (PD) is expected to reflect upon functional performance. As women are known to report more limitations even for same observed functional performance level, present study was designed to examine whether associations between neurological assessments and functional performance differ across genders.Methods. 14 men and 14 women with PD participated. Functional performance was assessed by measuring walking speeds on 10-meter walk test (10MWT) and by performing timed-up-and-go-test (TUG). Neurological assessment included Hoehn and Yahr Scale (HY), Movement Disorders Society Unified Parkinson’s Disease Rating Scale (MDS-UPDRS), Schwab and England Activities of Daily Living Scale (S-E), and Mini Mental State Examination (MMSE).Results. In women with PD, Kendall’s tau-b correlation analyses revealed significant correlations between functional performance tests and neurological assessment measures, with the exception in MMSE. No corresponding associations were found for men, although they demonstrated better functional performance, as expected.Conclusion. Men in similar clinical stage of the PD perform better on functional tests than women. Disease severity reflects upon functional performance differently in men and women with PD. Results indicate that when interpreting the assessment results of both functional performance and neurological assessment tests, the gender of the patient should be taken into consideration.


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