scholarly journals Assessing the role of basic control measures, antivirals and vaccine in curtailing pandemic influenza: scenarios for the US, UK and the Netherlands

2006 ◽  
Vol 4 (14) ◽  
pp. 505-521 ◽  
Author(s):  
M Nuño ◽  
G Chowell ◽  
A.B Gumel

An increasing number of avian flu cases in humans, arising primarily from direct contact with poultry, in several regions of the world have prompted the urgency to develop pandemic preparedness plans worldwide. Leading recommendations in these plans include basic public health control measures for minimizing transmission in hospitals and communities, the use of antiviral drugs and vaccination. This paper presents a mathematical model for the evaluation of the pandemic flu preparedness plans of the United States (US), the United Kingdom (UK) and the Netherlands. The model is used to assess single and combined interventions. Using data from the US, we show that hospital and community transmission control measures alone can be highly effective in reducing the impact of a potential flu pandemic. We further show that while the use of antivirals alone could lead to very significant reductions in the burden of a pandemic, the combination of transmission control measures, antivirals and vaccine gives the most ‘optimal’ result. However, implementing such an optimal strategy at the onset of a pandemic may not be realistic. Thus, it is important to consider other plausible alternatives. An optimal preparedness plan is largely dependent on the availability of resources; hence, it is country-specific . We show that countries with limited antiviral stockpiles should emphasize their use therapeutically (rather than prophylactically). However, countries with large antiviral stockpiles can achieve greater reductions in disease burden by implementing them both prophylactically and therapeutically. This study promotes alternative strategies that may be feasible and attainable for the US, UK and the Netherlands. It emphasizes the role of hospital and community transmission control measures in addition to the timely administration of antiviral treatment in reducing the burden of a flu pandemic. The latter is consistent with the preparedness plans of the UK and the Netherlands. Our results indicate that for low efficacy and coverage levels of antivirals and vaccine, the use of a vaccine leads to the greatest reduction in morbidity and mortality compared with the singular use of antivirals. However, as these efficacy and coverage levels are increased, the use of antivirals is more effective.

2020 ◽  
Vol 35 (11) ◽  
pp. 995-1006 ◽  
Author(s):  
William P. Hanage ◽  
Christian Testa ◽  
Jarvis T. Chen ◽  
Letitia Davis ◽  
Elise Pechter ◽  
...  

AbstractThe United States (US) has been among those nations most severely affected by the first—and subsequent—phases of the pandemic of COVID-19, the disease caused by SARS-CoV-2. With only 4% of the worldwide population, the US has seen about 22% of COVID-19 deaths. Despite formidable advantages in resources and expertise, presently the per capita mortality rate is over 585/million, respectively 2.4 and 5 times higher compared to Canada and Germany. As we enter Fall 2020, the US is enduring ongoing outbreaks across large regions of the country. Moreover, within the US, an early and persistent feature of the pandemic has been the disproportionate impact on populations already made vulnerable by racism and dangerous jobs, inadequate wages, and unaffordable housing, and this is true for both the headline public health threat and the additional disastrous economic impacts. In this article we assess the impact of missteps by the Federal Government in three specific areas: the introduction of the virus to the US and the establishment of community transmission; the lack of national COVID-19 workplace standards and enforcement, and lack of personal protective equipment (PPE) for workplaces as represented by complaints to the Occupational Safety and Health Administration (OSHA) which we find are correlated with deaths 16 days later (ρ = 0.83); and the total excess deaths in 2020 to date already total more than 230,000, while COVID-19 mortality rates exhibit severe—and rising—inequities in race/ethnicity, including among working age adults.


2020 ◽  
Vol 48 (1) ◽  
pp. 35-59
Author(s):  
Andrzej Purat ◽  
Paweł Bielicki

The main goal of our considerations is to analyse the most important conditions and dependencies that characterise Russian-Iranian relations from the beginning of the Arab Spring to the present day. We pay special attention to the infl uence of the United States on the development of diplomatic contacts between Moscow and Tehran and the conflict in Syria.Firstly, we describe the history of relations between the two countries after 1979 and the takeover of power by the religious leader, Ayatollah Khomeini, who, despite adopting an anti-Western course in international politics, did not show a desire to get closer to the Soviet neighbour. Secondly, we describe the relations of both countries from the collapse of the USSR to 2011, focusing on Iran’s role in influencing political processes in the post-Soviet area. Thirdly, we present the position of Russia and the Middle East about the war in Syria and the role of the Kurds. We also examine the impact of US policy on establishing links between Russia and Iran. Moreover, we raise economic issues and Moscow’s growing desire to dominate the Iranian economy and army.In the summary, we try to answer the question of what Russian-Iranian relations will look like in the future, especially in the era of the gradually ending war in Syria. Importantly, we refer to the issue of the US anti-Iranian rhetoric reinforced by Donald Trump and how it can influence the further strengthening of the Russia-Iran alliance.


2017 ◽  
Vol 10 (4) ◽  
pp. 12 ◽  
Author(s):  
Andrew Hughes Hallett ◽  
Ansgar Rannenberg ◽  
Sven Schreiber

Cogan et al. (2009, 2010) claimed that the stimulus package passed by the United States Congress in February 2009 had a multiplier far below one. However, the stimulus’ multiplier strongly depends on the assumed monetary policy response. Based on official statements from the Fed chairman, the general economic outlook, past behavior of the FOMC, optimal policy considerations, and from financial market expectations, we find that in February 2009, a reasonable prediction of the period of monetary accommodation would have exceeded 9 quarters. This implies that a plausible real time assessment of the stimulus’ effects would have been more optimistic than Cogan et al.’s.


2012 ◽  
Vol 36 (2) ◽  
pp. 149-165
Author(s):  
Antonio Medina-Rivera

The present investigation brings to light some of the changes associated with the use of English and Spanish in the US Catholic Church. The first part is an examination of the process of officialization from a historical perspective, acknowledging the impact of some groups or associations in the use of vernacular languages within the Church. The second part examines the role of acculturation during this process of officialization; and the final section analyzes the use of inclusive language in the Church, as an attempt to have a more gender-balanced institution. These three elements serve to provide a more complete perspective of the reality, expansion, revitalization and maintenance of the Spanish language in the United States. The article also reveals some of the language planning policies (direct and indirect) that have made an impact on the use of Spanish within US Catholicism.


2015 ◽  
Vol 4 (3) ◽  
pp. 442-475
Author(s):  
Peter R. Demant ◽  
Ariel Finguerut

The main purpose of this paper is to discuss the paradoxical consequences the so-called “Arab Spring”, from 2011 to 2014/15, which has led in various countries of the Arab world and beyond to different outcomes, but nowhere to stable democracy. We intend to discuss the outcomes of those political mobilizations and revolts, paying special attention to (a) the role of Islamist movements and (b) U.S reactions to the recent Mideast upheavals. We start with a general analysis and go to a few case studies (e.g. Egypt, Syria, and Turkey). In discussing the impact of Islamism, we attempt a classification of currents along two coordinates, one parameter contrasting Sunni and Shiite movements, the other laying out the continuum from pacific-modernist to violent jihadist. We defend that the dynamics of intra-Islamist tensions (such as Sunni jihadist against the Shiite Hizbullah-Syria-Iran axis) are no less crucial than the religious-secularist divide for understanding recent developments. Regarding US policies, we emphasize the dilemmas and contradictions within U.S government. We investigate the hypothesis that the US was caught largely unaware by the Arab Spring, and that its reactions suffered from the amorphousness of prior positions of the Obama administration, combined with leftovers from the Bush period. Internal contradictions of Obama’s Middle East doctrine coupled with a general isolationist trend have precluded the US from assuming more forceful policies, creating frustrations on all sides, and enflaming rather than dousing the fires of anti-Westernism in the Islamic world.Keywords: Arab Spring ; U.S policies ; Syria; jihadist.  Resumo: O principal objetivo deste artigo é discutir as consequências paradoxais da chamada "Primavera Árabe", que a partir de 2011 aos nossos dias produziu em vários países do mundo árabe diferentes resultados, mas em nenhum lugar chegou-se à democracia estável. Temos a intenção de discutir os resultados dessas mobilizações políticas e revoltas, com especial atenção para (a) o papel dos movimentos islâmicos e (b) as reações e posturas dos EUA ante os recentes levantes no Oriente Médio. De uma análise geral partiremos para estudos de caso (como Egito, Síria e Turquia). Ao discutir o impacto do islamismo, tentamos uma classificação das correntes ao longo de duas coordenadas, um deles contrastando movimentos sunitas e xiitas, e outro que define o continuum de pacifista - modernista para jihadista –violento. Postulamos que a dinâmica das tensões intra- islâmicos (como a de jihadistas sunitas contra o eixo Hezbollah -Síria- Irã xiita) não são menos importantes do que a divisão religiosa - secular para compreender os desdobramentos recentes. No que diz respeito aos EUA, destacamos os dilemas e contradições dentro do governo dos EUA. Nós investigamos a hipótese de que os EUA foi pego de surpresa em grande parte pela Primavera Árabe, e que as reações do governo Obama traduzem mais um recolhimento do que um novo engajamento.Palavras-chave: Primavera Árabe; Políticas dos EUA; Síria; jihadismo.   DOI: 10.20424/2237-7743/bjir.v4n3p442-475


2021 ◽  
Vol 19 (5-6) ◽  
pp. 597-625
Author(s):  
Martha I. Chew Sánchez

Abstract This article addresses the impact of settler colonialism by the Spanish and United States in the American continent in forming the base, development, and power of capitalism in the West. It provides a general overview of the United States’ unequal economic relationships with Latin American countries since the end of the nineteenth century to the present. It highlights the role evangelist groups have in changing the way coup d’états have been taking place in the region, in particular, to countries that had democratically elected presidents who were part of the “Pink Tide” and had a program to counterbalance neoliberal policies that were contributing to unprecedented economic inequality in their societies. One of the central questions in this work is the role of coloniality within Latin American countries and between the US and Latin America in the coup d’état against Evo Morales in Bolivia on November 10, 2019.


2020 ◽  
Author(s):  
Zheng-Meng Zhai ◽  
Yong-Shang Long ◽  
Jie Kang ◽  
Yi-Lin Li ◽  
Lang Zeng ◽  
...  

AbstractDue to the heterogeneity among the States in the US, predicting COVID-19 trends and quantitatively assessing the effects of government testing capability and control measures need to be done via a State-by-State approach. We develop a comprehensive model for COVID-19 incorporating time delays and population movements. With key parameter values determined by empirical data, the model enables the most likely epidemic scenarios to be predicted for each State, which are indicative of whether testing services and control measures are vigorous enough to contain the disease. We find that government control measures play a more important role than testing in suppressing the epidemic. The vast disparities in the epidemic trends among the States imply the need for long-term placement of control measures to fully contain COVID-19.


2020 ◽  
Author(s):  
Francesco Rigoli

Research has shown that stress impacts on people’s religious beliefs. However, several aspects of this effect remain poorly understood, for example regarding the role of prior religiosity and stress-induced anxiety. This paper explores these aspects in the context of the recent coronavirus emergency. The latter has impacted dramatically on many people’s well-being; hence it can be considered a highly stressful event. Through online questionnaires administered to UK and USA citizens professing either Christian faith or no religion, this paper examines the impact of the coronavirus crisis upon common people’s religious beliefs. We found that, following the coronavirus emergency, strong believers reported higher confidence in their religious beliefs while non-believers reported increased scepticism towards religion. Moreover, for strong believers, higher anxiety elicited by the coronavirus threat was associated with increased strengthening of religious beliefs. Conversely, for non-believers, higher anxiety elicited by the coronavirus thereat was associated with increased scepticism towards religious beliefs. These observations are consistent with the notion that stress-induced anxiety enhances support for the ideology already embraced before a stressful event occurs. This study sheds light on the psychological and cultural implications of the coronavirus crisis, which represents one of the most serious health emergencies in recent times.


Author(s):  
Aref Emamian

This study examines the impact of monetary and fiscal policies on the stock market in the United States (US), were used. By employing the method of Autoregressive Distributed Lags (ARDL) developed by Pesaran et al. (2001). Annual data from the Federal Reserve, World Bank, and International Monetary Fund, from 1986 to 2017 pertaining to the American economy, the results show that both policies play a significant role in the stock market. We find a significant positive effect of real Gross Domestic Product and the interest rate on the US stock market in the long run and significant negative relationship effect of Consumer Price Index (CPI) and broad money on the US stock market both in the short run and long run. On the other hand, this study only could support the significant positive impact of tax revenue and significant negative impact of real effective exchange rate on the US stock market in the short run while in the long run are insignificant. Keywords: ARDL, monetary policy, fiscal policy, stock market, United States


Author(s):  
Anne Nassauer

This book provides an account of how and why routine interactions break down and how such situational breakdowns lead to protest violence and other types of surprising social outcomes. It takes a close-up look at the dynamic processes of how situations unfold and compares their role to that of motivations, strategies, and other contextual factors. The book discusses factors that can draw us into violent situations and describes how and why we make uncommon individual and collective decisions. Covering different types of surprise outcomes from protest marches and uprisings turning violent to robbers failing to rob a store at gunpoint, it shows how unfolding situations can override our motivations and strategies and how emotions and culture, as well as rational thinking, still play a part in these events. The first chapters study protest violence in Germany and the United States from 1960 until 2010, taking a detailed look at what happens between the start of a protest and the eruption of violence or its peaceful conclusion. They compare the impact of such dynamics to the role of police strategies and culture, protesters’ claims and violent motivations, the black bloc and agents provocateurs. The analysis shows how violence is triggered, what determines its intensity, and which measures can avoid its outbreak. The book explores whether we find similar situational patterns leading to surprising outcomes in other types of small- and large-scale events: uprisings turning violent, such as Ferguson in 2014 and Baltimore in 2015, and failed armed store robberies.


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