Evolution of resistance with sequential application of insecticides in time and space

1989 ◽  
Vol 238 (1292) ◽  
pp. 245-276 ◽  

The effect, on the evolution of resistance, of alternating two unrelated insecticides in space or in time (or both) is studied. Transient polymorphism is shown to occur under certain conditions of mating, selection and migration. In some situations, the transient polymorphism can show a sharp decline before the alleles recover to fixation. Alternating a single insecticide in space, and in space and time, is also considered. Neither alternation in space nor in time shows any advantage with regard to delaying the onset of resistance. The most promising mode is to alternate the presence and absence of a single insecticide in both space and time, especially if it is applied at the larval stage and if some form of biological control is used in the regions where no insecticide is applied.

Author(s):  
Emily Thomas

This chapter explores Isaac Barrow’s account of time and space. Barrow’s account is important, partly because it is often argued to be one of the sources that Newton drew on in constructing his absolutism. Although Barrow is usually read as a pre-Newtonian absolutist, this chapter argues that Barrow is in fact a modal relationist, identifying space and time with the relational modes of bodies. This new reading entails that Barrow’s account of time may not have played as large a role in the development of Newton’s work as has been thought, but it also raises the possibility that Leibniz drew on Barrow’s relationism.


Genetics ◽  
1993 ◽  
Vol 133 (3) ◽  
pp. 711-727
Author(s):  
B K Epperson

Abstract The geographic distribution of genetic variation is an important theoretical and experimental component of population genetics. Previous characterizations of genetic structure of populations have used measures of spatial variance and spatial correlations. Yet a full understanding of the causes and consequences of spatial structure requires complete characterization of the underlying space-time system. This paper examines important interactions between processes and spatial structure in systems of subpopulations with migration and drift, by analyzing correlations of gene frequencies over space and time. We develop methods for studying important features of the complete set of space-time correlations of gene frequencies for the first time in population genetics. These methods also provide a new alternative for studying the purely spatial correlations and the variance, for models with general spatial dimensionalities and migration patterns. These results are obtained by employing theorems, previously unused in population genetics, for space-time autoregressive (STAR) stochastic spatial time series. We include results on systems with subpopulation interactions that have time delay lags (temporal orders) greater than one. We use the space-time correlation structure to develop novel estimators for migration rates that are based on space-time data (samples collected over space and time) rather than on purely spatial data, for real systems. We examine the space-time and spatial correlations for some specific stepping stone migration models. One focus is on the effects of anisotropic migration rates. Partial space-time correlation coefficients can be used for identifying migration patterns. Using STAR models, the spatial, space-time, and partial space-time correlations together provide a framework with an unprecedented level of detail for characterizing, predicting and contrasting space-time theoretical distributions of gene frequencies, and for identifying features such as the pattern of migration and estimating migration rates in experimental studies of genetic variation over space and time.


Genetics ◽  
2003 ◽  
Vol 163 (1) ◽  
pp. 429-446 ◽  
Author(s):  
Jinliang Wang ◽  
Michael C Whitlock

Abstract In the past, moment and likelihood methods have been developed to estimate the effective population size (Ne) on the basis of the observed changes of marker allele frequencies over time, and these have been applied to a large variety of species and populations. Such methods invariably make the critical assumption of a single isolated population receiving no immigrants over the study interval. For most populations in the real world, however, migration is not negligible and can substantially bias estimates of Ne if it is not accounted for. Here we extend previous moment and maximum-likelihood methods to allow the joint estimation of Ne and migration rate (m) using genetic samples over space and time. It is shown that, compared to genetic drift acting alone, migration results in changes in allele frequency that are greater in the short term and smaller in the long term, leading to under- and overestimation of Ne, respectively, if it is ignored. Extensive simulations are run to evaluate the newly developed moment and likelihood methods, which yield generally satisfactory estimates of both Ne and m for populations with widely different effective sizes and migration rates and patterns, given a reasonably large sample size and number of markers.


2021 ◽  
Vol 1 (24) ◽  
pp. 87-94
Author(s):  
Mikhail N. Kulakovsky ◽  

The article examines peculiarities of the use of parentheses in A. Belyi's lyrics and prose. The author describes the main aspects of analysing parentheses in modern linguistics: description of their functional features, their link with the main body of the statement, parentheses as text forming means, time and space organization of the text, realization of the author's irony, means of conveying evaluative information, ways of comparing, metatextual comment, informative actualization, means of creating a dialogue in a fiction text, usage parentheses in particular genres. This study identifies the most characteristic functions of parentheses in A. Belyi's texts, the connection of parentheses with different textual levels and their role in the overall structure of the literary text. Both the most typical and unique functions of parentheses in A. Belyi's works are described in detail. The main functional features of parentheses are defined in terms of space and time organization of the text and the interaction of various informative and subjective speech plans of the text. The article outlines the main aspects of language game within the framework of parentheses, as well as the means of interaction between the parentheses and the main context, presented in the poetry and prose of A. Belyi. The analysis suggests that the most typical functions of the parentheses in A. Belyi's works are detailed portrayal of the character, switching space and time registers, making comparisons, clarification, and conveying emotional and evaluative information.


2002 ◽  
Vol 752 ◽  
Author(s):  
Peter Lingenfelter ◽  
Tomasz Sokalski ◽  
Andrzej Lewenstam

ABSTRACTA numerical model is presented for analyzing the propagation of ionic concentrations and electrical potential in space and time in the solution ion-exchanging membrane system. Diffusion and migration according to the Nernst-Planck (NP) flux equation govern the transport of ions, and the electrical interaction of the species is described by the Poisson (P) equation. These two equations and the continuity equation form a system of partial non-linear differential equations that is solved numerically. As a result of the physicochemical properties of the system, both the contact/boundary potential and the diffusion potential contribute to the overall membrane potential. It is shown that interpreting the electrical potential of ion-exchanging membranes exclusively in terms of boundary potential at steady-state is incorrect. The Nernst-Planck-Poisson (NPP) model is general and applies to ions of any charge in space and time domains.


2021 ◽  
Vol 1 (2) ◽  
pp. 80-87
Author(s):  
Toji Omonovich Norov ◽  

The universe, the space that make up their basis planets in it, their creation, the main essence of their creation, form, composition, meaning, movements, interactions, their influence on human life and activities, the role of man in the universe and in life on Earth, life, the criteria of activity and processes occurring in time and space have long been of interest to humanity. One of the main problems in the history of philosophy is the question of space and time. This problem was defined in different ways in the great schools of thought by thinkers of different periods. One of these great thinkers is Alisher Navoi. Navoi's works, along with other socio-philosophical themes, uniquely express and analyze the problems of the firmament and time. Its main feature is that it is based on the divine (pantheistic) religion, Islam, its holy book, the Koran and other theological sources, as well as on the secrets of nature and the Universe, the main miracle of Allah - human intelligence, the power of enlightenment, they are the key revealing all these secrets.


Author(s):  
Marjorie Mayo

Moving forward, this chapter explores ways of sharing learning, as the basis for building solidarity across time and space. The first example comes from India, as workers and communities shared their research on industrial malpractices, leading to the human and environmental disaster, when more than 40 tons of methyl isocyanate gas from a pesticide plant in Bhopal, India. Research findings and experiences were shared across the globe, supporting Indian communities in their struggles for justice and a safer environment. The second example comes from London’s Docklands where communities and local workforces shared their learning over the years, developing the case for alternative approaches to planning, sharing ideas about redevelopment to meet people’s needs rather than to promote private profitability.


PLoS ONE ◽  
2018 ◽  
Vol 13 (12) ◽  
pp. e0207610 ◽  
Author(s):  
Paula Casanovas ◽  
Stephen L. Goldson ◽  
Jason M. Tylianakis

2020 ◽  
Vol 63 (3) ◽  
pp. 616-639
Author(s):  
Duduzile S. Ndlovu

Abstract:Migration debates tend to focus on the numbers of people moving, whether they are economic migrants or asylum seekers, deserving or not of protection. This categorization usually rests on national identity, necessitating simplified one-dimensional representations. Ndlovu uses a case study of Zimbabwean migrants memorializing Gukurahundi in Johannesburg to highlight the ways in which migration narratives can be more complex and how they may shift over time. She presents Gukurahundi and the formation of the MDC in Zimbabwe, along with xenophobic violence in South Africa, as examples of the ways that the meanings of national and ethnic identities are contested by the migrants and influenced by political events across time and space.


1979 ◽  
Vol 28 (4) ◽  
pp. 259-260 ◽  
Author(s):  
Milada Zahálková

Out of a total of 1025 twin births occurring in 11 South Moravian districts from 1972 to 1976, 638 occurred in the same time and space interval (P = 0.00037). The observed clustering suggests the existence of environmental factors influencing twinning rates.


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