scholarly journals Estimation of the transmission time of stimulus-locked responses: modelling and stochastic phase resetting analysis

2005 ◽  
Vol 360 (1457) ◽  
pp. 995-999 ◽  
Author(s):  
Peter A Tass

A model of two coupled phase oscillators is studied, where both oscillators are subject to random forces but only one oscillator is repetitively stimulated with a pulsatile stimulus. A pulse causes a reset, which is transmitted to the other oscillator via the coupling. The transmission time of the cross-trial (CT) averaged responses, i.e. the difference in time between the maxima of the CT averaged responses of both oscillators differs from the time difference between the maxima of the oscillators' resets. In fact, the transmission time of the CT averaged responses directly corresponds to the phase difference in the stable synchronized state with integer multiples of the oscillators' mean period added to it. With CT averaged responses it is impossible to reliably estimate the time elapsing, owing to the stimulus' action being transmitted between the two oscillators.

2020 ◽  
Vol 15 ◽  
pp. 155892502093972
Author(s):  
Guifang He ◽  
Chunfu Sheng ◽  
Hongwei He ◽  
Rong Zhou ◽  
Ding Yuan ◽  
...  

As soft elements for force transmission, braided fiber ropes play important roles in many fields where the fiber ropes are used bent over sheaves, while the relevant experiments are time-consuming and expensive. Computational simulation is a promising choice for evaluating the performance of fiber ropes when bent over a sheave. This article presents two methods that could be employed to build a model of braided rope bent over a sheave. One is the mathematical method which deduces the exact mathematical equations of braiding curves based on the Frenet–Serret frame. The spatial equations, considering the phase difference of strands in the same direction and the difference of strands’ projection in different directions, are discussed carefully. The final equation of braided strands is confirmed by modeling the braided rope in Maple® 17. The other method, which is inspired by the analysis of braiding movements, is based on the intersection of surfaces of braiding surface and helical surface which are introduced and defined based on the motion analysis of bobbins and take-up roller. The SolidWorks® 2018 is successfully employed to realize the modeling process.


1980 ◽  
Vol 59 (6) ◽  
pp. 411-421 ◽  
Author(s):  
Catherine A. Knock ◽  
H. E. De Wardener

1. Five rats were volume expanded by infusing a volume of blood equivalent to one-third of the estimated blood volume. In six control experiments the same transfusion was given without expanding the blood volume, as an equal volume of blood was simultaneously removed. Sodium excretion increased significantly more after the blood volume was expanded than in the control experiments. 2. Pairs of rats placed on opposite scale pans of a trip balance were cross-circulated by means of arteriovenous bypasses. The blood volume of the rats could be kept constant by keeping the balance in equilibrium. 3. One of each pair of rats received a blood transfusion which either did or did not expand its blood volume. Sodium excretion was measured in the transfused rat and in the recipient rat, the blood volume of which was kept constant. 4. Sodium excretion in the six recipient rats cross-circulated with rats with an expanded blood volume was not significantly different from that in six recipient rats, cross-circulated with rats given a transfusion which did not expand the blood volume. 5. The cross-circulation experiments were repeated, with the difference that the urine of the transfused rat was reinfused. Under these conditions, sodium excretion in 11 recipient rats cross-circulated with blood volume expanded rats was significantly greater than in eight recipient rats cross-circulated with rats given a transfusion which did not expand the blood volume. 6. In cross-circulation experiments in which a blood transfusion was not given urine reinfusion of one rat did not affect sodium excretion of the other rat. 7. It is concluded that the rise in urinary sodium excretion which occurs in an isovolaemic recipient rat cross-circulated with a urine reinfused rat with an expanded blood volume is due to a change in the concentration of a circulating substance.


Parasitology ◽  
1973 ◽  
Vol 67 (1) ◽  
pp. 17-27 ◽  
Author(s):  
A. I. Oxbrow

Mice immunized by single pyrimethamine terminated infections of Plasmodium berghei berghei, strain NK65 or the Nigerian P. berghei-like parasite, N67, were immune to challenge by P.b. berghei, P.b. yoelii strain 17X, P.b. killicki strain 194ZZ and N67. Mice similarly immunized against P.b. yoelii were only immune or N67 resulted in infections comparable to those found in normal mice. Mice immunized against P.b. killicki were similar except that they also possessed some protection against challenge by N67. Evidence was obtained which indicated that the difference between P.b. yoelii and N67 was not associated with the virulence of the parasites. Prolonged exposure to P.b. yoelii infection slightly increased homologous and heterologous immunity. Two lines of parasites were crossed; one of these was derived from P.b. yoelii and the other from N67. They differed in pyrimethamine sensitivity, glucose phosphate isomerase type and the ability to survive in mice immunized against P.b. yoelii. Ten lines of parasites showing the P.b. yoelii characters of pyrimethamine resistance and GPI-1 were isolated in drug treated mice immune to P.b. yoelii challenge. Twenty-one clones were isolated without drug or antibody selection from the parasites resulting from the cross between P.b. yoelii and N67. Sixteen of these clones were classified according to the markers which they possessed and six were found to be recombinant in character. The experiments showed that genetic recombination occurred as a frequent event in P. berghei and involved factors which control the cross-immunity produced following infection with these parasites.


2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Somrita Ray ◽  
Monoj Kumar Sen ◽  
Alendu Baura ◽  
Bidhan Chandra Bag

We have studied in this paper the dynamics of globally coupled phase oscillators having the Lorentzian frequency distribution with zero mean in the presence of both time delay and noise. Noise may be Gaussian or non-Gaussian in characteristics. In the limit of zero noise strength, we find that the critical coupling strength (CCS) increases linearly as a function of time delay. Thus the role of time delay in the dynamics for the deterministic system is qualitatively equivalent to the effect of frequency fluctuations of the phase oscillators by additive white noise in absence of time delay. But for the stochastic model, the critical coupling strength grows nonlinearly with the increase of the time delay. The linear dependence of the critical coupling strength on the noise intensity also changes to become nonlinear due to creation of additional phase difference among the oscillators by the time delay. We find that the creation of phase difference plays an important role in the dynamics of the system when the intrinsic correlation induced by the finite correlation time of the noise is small. We also find that the critical coupling is higher for the non-Gaussian noise compared to the Gaussian one due to higher effective noise strength.


Author(s):  
V. Mizuhira ◽  
Y. Futaesaku

Previously we reported that tannic acid is a very effective fixative for proteins including polypeptides. Especially, in the cross section of microtubules, thirteen submits in A-tubule and eleven in B-tubule could be observed very clearly. An elastic fiber could be demonstrated very clearly, as an electron opaque, homogeneous fiber. However, tannic acid did not penetrate into the deep portion of the tissue-block. So we tried Catechin. This shows almost the same chemical natures as that of proteins, as tannic acid. Moreover, we thought that catechin should have two active-reaction sites, one is phenol,and the other is catechole. Catechole site should react with osmium, to make Os- black. Phenol-site should react with peroxidase existing perhydroxide.


1973 ◽  
Vol 29 (02) ◽  
pp. 490-498 ◽  
Author(s):  
Hiroh Yamazaki ◽  
Itsuro Kobayashi ◽  
Tadahiro Sano ◽  
Takio Shimamoto

SummaryThe authors previously reported a transient decrease in adhesive platelet count and an enhancement of blood coagulability after administration of a small amount of adrenaline (0.1-1 µg per Kg, i. v.) in man and rabbit. In such circumstances, the sensitivity of platelets to aggregation induced by ADP was studied by an optical density method. Five minutes after i. v. injection of 1 µg per Kg of adrenaline in 10 rabbits, intensity of platelet aggregation increased to 115.1 ± 4.9% (mean ± S. E.) by 10∼5 molar, 121.8 ± 7.8% by 3 × 10-6 molar and 129.4 ± 12.8% of the value before the injection by 10”6 molar ADP. The difference was statistically significant (P<0.01-0.05). The above change was not observed in each group of rabbits injected with saline, 1 µg per Kg of 1-noradrenaline or 0.1 and 10 µg per Kg of adrenaline. Also, it was prevented by oral administration of 10 mg per Kg of phenoxybenzamine or propranolol or aspirin or pyridinolcarbamate 3 hours before the challenge. On the other hand, the enhancement of ADP-induced platelet aggregation was not observed in vitro, when 10-5 or 3 × 10-6 molar and 129.4 ± 12.8% of the value before 10∼6 molar ADP was added to citrated platelet rich plasma (CPRP) of rabbit after incubation at 37°C for 30 second with 0.01, 0.1, 1, 10 or 100 µg per ml of adrenaline or noradrenaline. These results suggest an important interaction between endothelial surface and platelets in connection with the enhancement of ADP-induced platelet aggregation by adrenaline in vivo.


Author(s):  
Philip Isett

This chapter presents the equations and calculations for energy approximation. It establishes the estimates (261) and (262) of the Main Lemma (10.1) for continuous solutions; these estimates state that we are able to accurately prescribe the energy that the correction adds to the solution, as well as bound the difference between the time derivatives of these two quantities. The chapter also introduces the proposition for prescribing energy, followed by the relevant computations. Each integral contributing to the other term can be estimated. Another proposition for estimating control over the rate of energy variation is given. Finally, the coarse scale material derivative is considered.


Metahumaniora ◽  
2017 ◽  
Vol 7 (3) ◽  
pp. 378
Author(s):  
Vincentia Tri Handayani

AbstrakFolklor yang menghasilkan tradisi lisan merupakan perwujudan budaya yang lahirdari pengalaman kelompok masyarakat. Salah satu bentuk tradisi lisan adalah ungkapan yangmengandung unsur budaya lokal dalam konstruksinya yang tidak dimiliki budaya lainnya.Ungkapan idiomatis memberikan warna pada bahasa melalui penggambaran mental. Dalambahasa Perancis, ungkapan dapat berupa locution dan expression. Perbedaan motif acuansuatu ungkapan dapat terlihat dari pengaruh budaya masyarakat pengguna bahasa. Sebuahleksem tidak selalu didefinisikan melalui unsur minimal, tidak juga melalui kata-kata,baik kata dasar atau kata kompleks, namun dapat melalui kata-kata beku yang maknanyatetap. Hubungan analogis dari makna tambahan yang ada pada suatu leksem muncul dariidentifikasi semem yang sama. Semem tersebut mengarah pada term yang diasosiasikan danyang diperkaya melalui konteks (dalam ungkapan berhubungan dengan konteks budaya).Kata kunci: folklor, ungkapan, struktur, makna idiomatis, kebudayaanAbstractFolklore which produces the oral tradition is a cultural manifestation born out theexperience of community groups. One form of the oral tradition is a phrase that containsthe elements of local culture in its construction that is not owned the other culture. Theidiomatic phrase gives the color to the language through the mental representation. InFrench, the expression can consist of locution and expression. The difference motivesreference of an expression can be seen from the influence of the cultural community thelanguage users. A lexeme is not always defined through a minimal element, nor throughwords, either basic or complex words, but can be through the frost words whose meaningsare fixed. The analogical connection of the additional meanings is on a lexeme arises fromthe identification of the same meaning. The meaning ‘semem’ leads to the associated termsand which are enriched through the context (in idiom related to the cultural context).Keywords : folklore, idioms, structure, idiom meaning, cultureI PENDAHULUAN


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