scholarly journals Thevgll3locus controls age at maturity in wild and domesticated Atlantic salmon (Salmo salarL.) males

2015 ◽  
Author(s):  
Fernando Ayllon ◽  
Erik Kjærner-Semb ◽  
Tomasz Furmanek ◽  
Vidar Wennevik ◽  
Monica F Solberg ◽  
...  
Keyword(s):  
Atlantic Salmon ◽  
Homo Sapiens ◽  
Complex Nature ◽  
Missense Mutations ◽  
Age At Maturity ◽  
Specific Sequence ◽  
Wild Salmon ◽  
Late Maturity ◽  
Age At Maturation ◽  
Sexually Mature

Wild and domesticated Atlantic salmon males display large variation for sea age at sexual maturation, which varies between 1-5 years. Previous studies have uncovered a genetic predisposition for age at maturity with moderate heritability, thus suggesting a polygenic or complex nature of this trait. The aim of this study was to identify associated genetic loci, genes and ultimately specific sequence variants conferring sea age at maturity in salmon. We performed a GWAS using a pool sequencing approach (20 individuals per river and trait) of salmon returning to rivers as sexually mature either after one sea winter (2009) or three sea winters (2011) in six rivers in Norway. The study revealed one major selective sweep, which covered 76 significant SNP in which 74 were found in a 370 kb region of chromosome 25. Genotyping other smolt year classes of wild salmon and domesticated salmon confirmed this finding. Genotyping domesticated fish narrowed the haplotype region to four SNPs covering 2386 bp, containing thevgll3gene, including two missense mutations explaining 33-36% phenotypic variation. This study demonstrates a single locus playing a highly significant role in governing sea age at maturation in this species. The SNPs identified may be both used as markers to guide breeding for late maturity in salmon aquaculture and in monitoring programs of wild salmon. Interestingly, a SNP in proximity of the VGLL3 gene in human (Homo sapiens), has previously been linked to age at puberty suggesting a conserved mechanism for timing of puberty in vertebrates.

Movements and survival of sonically tagged farmed Atlantic salmon released in Cobscook Bay, Maine, USA

2006 ◽  
Vol 63 (7) ◽  
pp. 1218-1223 ◽  
Author(s):  
Frederick G. Whoriskey ◽  
Paul Brooking ◽  
Gino Doucette ◽  
Stephen Tinker ◽  
Jonathan W. Carr
Keyword(s):  
Atlantic Salmon ◽  
Salmo Salar ◽  
Coastal Zone ◽  
Coastal Region ◽  
Movement Patterns ◽  
Tidal Currents ◽  
Bay Of Fundy ◽  
Wild Salmon ◽  
Receiver Array ◽  
Farmed Atlantic Salmon

Abstract We sonically tagged and released farmed Atlantic salmon (Salmo salar) from a cage site in Cobscook Bay, Maine, USA. The fish were released in January (n = 75) and in April and May (n = 198) 2004 to study their movement patterns and survival and to assess the possibility of recapturing them. Inshore and offshore waters in this region are subject to intense tidal currents. Tagged salmon dispersed >1 km from the cage site within a few hours of their release. Mortality was high within Cobscook Bay and the surrounding coastal region (56% of the winter (January) releases; 84% of the spring (March) releases), probably the result of seal predation. Most surviving fish exited the coastal zone and entered the Bay of Fundy along the routes of the dominant tidal currents, passing through Canadian waters. No tagged fish were detected during the wild salmon spawning season in autumn 2004 in any of the 43 monitored salmon rivers draining into the Bay of Fundy, or during 2005 either in the Magaguadavic River, the site of the hatchery in which the fish were reared to the smolt stage, or by a limited coastal receiver array.

Unidirectional Natural Hybridization between Brown Trout (Salmo trutta) and Atlantic Salmon (S. salar) in Newfoundland

1992 ◽  
Vol 49 (9) ◽  
pp. 1953-1958 ◽  
Author(s):  
Colin McGowan ◽  
William S. Davidson
Keyword(s):  
Atlantic Salmon ◽  
Brown Trout ◽  
Salmo Trutta ◽  
Dna Analysis ◽  
Juvenile Fish ◽  
Natural Hybridization ◽  
Major Influence ◽  
Isolating Mechanisms ◽  
Brown Trout Salmo Trutta ◽  
Sexually Mature

Protein electrophoresis and mitochondrial DNA analysis were used to detect the frequency and direction of natural hybridization between brown trout (Salmo trutta) and Atlantic salmon (S. salar) in nine Newfoundland rivers. In total, 37 hybrids were discovered in a sample of 792 juvenile fish for a regional frequency of 4.67%. Local frequencies ranged from 0.00 to 18.75% and were significantly heterogeneous. All of the hybrids sampled were produced from matings between female brown trout and male Atlantic salmon. Possible reasons for the breakdown of prereproductive isolating mechanisms between these species are considered. Reproductive characteristics of the populations involved appear to have a major influence on the dynamics of hybridization between these species in Newfoundland. It is proposed that an abundance of sexually mature Atlantic salmon parr in Newfoundland streams is responsible for both the frequency and direction of hybridization observed in this study.

Kidney Disease in Juvenile Atlantic Salmon (Salmo salar) in the Margaree River

1969 ◽  
Vol 26 (9) ◽  
pp. 2535-2537 ◽  
Author(s):  
J. H. C. Pippy
Keyword(s):  
Kidney Disease ◽  
Atlantic Salmon ◽  
Salmo Salar ◽  
River System ◽  
Juvenile Salmon ◽  
Wild Salmon ◽  
Atlantic Salmon Salmo Salar ◽  
Bacterial Kidney Disease ◽  
Juvenile Atlantic Salmon

Bacterial kidney disease was presumptively identified in each of 25 hatchery-reared juvenile salmon (Salmo salar) but in only 2 of 235 wild juveniles in the Margaree River system. Apparently spread of disease from the hatchery to wild salmon in the river is very gradual.

Transferrin Polymorphism in Atlantic Salmon (Salmo salar)

1970 ◽  
Vol 27 (9) ◽  
pp. 1617-1625 ◽  
Author(s):  
Dag Møller
Keyword(s):  
Atlantic Salmon ◽  
Salmo Salar ◽  
Genetic Basis ◽  
Gene Frequencies ◽  
Wild Salmon ◽  
Atlantic Salmon Salmo Salar ◽  
Different Populations ◽  
Transferrin Polymorphism ◽  
Starch Agar

Three main patterns of transferrins, made up of two molecular types, were found by starch–agar electrophoresis in plasma of hatchery and wild Atlantic salmon (Salmo salar).Distributions of the observed patterns from progenies of three hatchery matings agreed with expected Mendelian distributions in offspring of known parentage, implying that the bands have their origin in two codominant alleles. In nearly all samples of the wild salmon the genetic basis of transferrin variation was demonstrated by nonsignificant differences between observed and expected distributions when the Hardy–Weinberg formula was applied.Frequencies of the TfA allele differed in samples from different rivers and within the same river; the Atlantic salmon forms genetically different populations. Interchange of stocks probably influenced the values of the different gene frequencies found.

scholarly journals Transcription Profiles of Age-at-Maturity-Associated Genes Suggest Cell Fate Commitment Regulation as a Key Factor in the Atlantic Salmon Maturation Process

2019 ◽  
Vol 10 (1) ◽  
pp. 235-246 ◽  
Author(s):  
Johanna Kurko ◽  
Paul V. Debes ◽  
Andrew H. House ◽  
Tutku Aykanat ◽  
Jaakko Erkinaro ◽  
...  
Keyword(s):  
Atlantic Salmon ◽  
Cell Fate ◽  
Molecular Mechanisms ◽  
Genome Wide Association Study ◽  
Expression Patterns ◽  
Hippo Signaling ◽  
Age At Maturity ◽  
Specific Expression ◽  
Hpg Axis ◽  
Tissue Specific

Despite recent taxonomic diversification in studies linking genotype with phenotype, follow-up studies aimed at understanding the molecular processes of such genotype-phenotype associations remain rare. The age at which an individual reaches sexual maturity is an important fitness trait in many wild species. However, the molecular mechanisms regulating maturation timing processes remain obscure. A recent genome-wide association study in Atlantic salmon (Salmo salar) identified large-effect age-at-maturity-associated chromosomal regions including genes vgll3, akap11 and six6, which have roles in adipogenesis, spermatogenesis and the hypothalamic-pituitary-gonadal (HPG) axis, respectively. Here, we determine expression patterns of these genes during salmon development and their potential molecular partners and pathways. Using Nanostring transcription profiling technology, we show development- and tissue-specific mRNA expression patterns for vgll3, akap11 and six6. Correlated expression levels of vgll3 and akap11, which have adjacent chromosomal location, suggests they may have shared regulation. Further, vgll3 correlating with arhgap6 and yap1, and akap11 with lats1 and yap1 suggests that Vgll3 and Akap11 take part in actin cytoskeleton regulation. Tissue-specific expression results indicate that vgll3 and akap11 paralogs have sex-dependent expression patterns in gonads. Moreover, six6 correlating with slc38a6 and rtn1, and Hippo signaling genes suggests that Six6 could have a broader role in the HPG neuroendrocrine and cell fate commitment regulation, respectively. We conclude that Vgll3, Akap11 and Six6 may influence Atlantic salmon maturation timing via affecting adipogenesis and gametogenesis by regulating cell fate commitment and the HPG axis. These results may help to unravel general molecular mechanisms behind maturation.

IN VIVO METABOLISM OF STEROID HORMONES BY SOCKEYE SALMON: (A) IMPAIRED HORMONE CLEARANCE IN MATURE AND SPAWNED PACIFIC SALMON (O. NERKA) (B) PRECURSORS OF 11-KETOTESTOSTERONE

1963 ◽  
Vol 41 (4) ◽  
pp. 875-887 ◽  
Author(s):  
D. R. Idler ◽  
B. Truscott ◽  
H. C. Freeman ◽  
V. Chang ◽  
P. J. Schmidt ◽  
...  
Keyword(s):  
Atlantic Salmon ◽  
Sockeye Salmon ◽  
Pacific Salmon ◽  
In Vivo Metabolism ◽  
Hormone Metabolism ◽  
The Pacific ◽  
Imminent Death ◽  
High Concentrations ◽  
Sexually Mature

Intra-arterially injected cortisone-4-C14 and cortisol-4-C14 were cleared from the plasma of sexually mature and spawned sockeye salmon (O. nerka) at a much slower rate than from the plasma of immature sockeye and spawned Atlantic salmon (S. salar). The results explain the elevated hormone levels found in the blood of mature and spawned sockeye salmon. The normal clearance rate found with Atlantic salmon, which frequently survive spawning, would indicate that the impaired hormone metabolism was associated with the imminent death of the Pacific salmon rather than with the act of spawning.Testosterone and 17α-hydroxyprogesterone were found to be precursors of 11-ketotestosterone, a sex hormone found in high concentrations in the blood of mature sockeye salmon. Testosterone was also formed in vivo from 17α-hydroxyprogesterone. The results suggest more than one pathway for the synthesis of 11-ketotestosterone in salmon. Cortisol was converted to cortisone but no conversion of the former to 11-ketotestosterone could be demonstrated.

IN VIVO METABOLISM OF STEROID HORMONES BY SOCKEYE SALMON: (A) IMPAIRED HORMONE CLEARANCE IN MATURE AND SPAWNED PACIFIC SALMON (O. NERKA) (B) PRECURSORS OF 11-KETOTESTOSTERONE

1963 ◽  
Vol 41 (1) ◽  
pp. 875-887
Author(s):  
D. R. Idler ◽  
B. Truscott ◽  
H. C. Freeman ◽  
V. Chang ◽  
P. J. Schmidt ◽  
...  
Keyword(s):  
Atlantic Salmon ◽  
Sockeye Salmon ◽  
Pacific Salmon ◽  
In Vivo Metabolism ◽  
Hormone Metabolism ◽  
The Pacific ◽  
Imminent Death ◽  
High Concentrations ◽  
Sexually Mature

Intra-arterially injected cortisone-4-C14 and cortisol-4-C14 were cleared from the plasma of sexually mature and spawned sockeye salmon (O. nerka) at a much slower rate than from the plasma of immature sockeye and spawned Atlantic salmon (S. salar). The results explain the elevated hormone levels found in the blood of mature and spawned sockeye salmon. The normal clearance rate found with Atlantic salmon, which frequently survive spawning, would indicate that the impaired hormone metabolism was associated with the imminent death of the Pacific salmon rather than with the act of spawning.Testosterone and 17α-hydroxyprogesterone were found to be precursors of 11-ketotestosterone, a sex hormone found in high concentrations in the blood of mature sockeye salmon. Testosterone was also formed in vivo from 17α-hydroxyprogesterone. The results suggest more than one pathway for the synthesis of 11-ketotestosterone in salmon. Cortisol was converted to cortisone but no conversion of the former to 11-ketotestosterone could be demonstrated.

Potential for dispersal of Gyrodactylus salaris (Platyhelminthes, Monogenea) by sea-running stages of the Atlantic salmon (Salmo salar): field and laboratory studies

1998 ◽  
Vol 55 (2) ◽  
pp. 507-514 ◽  
Author(s):  
Arnulf Soleng ◽  
Tor A Bakke ◽  
Lars P Hansen
Keyword(s):  
Atlantic Salmon ◽  
Salmo Salar ◽  
River Mouth ◽  
Infected Fish ◽  
Surface Salinity ◽  
Wild Salmon ◽  
Atlantic Salmon Salmo Salar ◽  
Water Dispersal ◽  
Salmon Parr ◽  
Salmon Smolt

Population growth of Gyrodactylus salaris increased exponentially on Atlantic salmon (Salmo salar) smolts in laboratory experiments conducted at 12.0°C. Furthermore, G. salaris was transmitted successfully from salmon smolt to parr at 0.0, 7.5, 10.0, and 20.0%° salinity and reproduced in fresh water after direct transfer from 7.5%° (16 days), 20.0%° (4 and 8 h), and 33.0%° (5, 15, and 30 min). No G. salaris were observed on salmon parr exposed to 33.0%° for 60 min. The prevalence of G. salaris on wild salmon smolts caught approximately 25 km from the river mouth in the Drammensfjord (surface salinity 2.0-3.5%°) was 71.2% compared with 88.0% on those from the neighbouring River Lierelva. Adult wild salmon caught as prespawners, spawners, and postspawners (kelts) in the River Drammenselva were infected with G. salaris. The prevalence and abundance increased from autumn to spring, in contrast with earlier studies on salmon parr, demonstrating the possible importance of adult salmon as reservoirs for G. salaris during winter. The results support the hypothesis of brackish water dispersal of G. salaris by infected salmonids migrating in estuaries and fjords. The use of salt as a disinfectant against G. salaris in hatcheries, and the stocking of possibly infected fish into brackish and seawater, should also be reexamined.

Comparative Agonistic and Feeding Behavior of Hatchery-Reared and Wild Salmon in Aquaria

1968 ◽  
Vol 25 (1) ◽  
pp. 1-14 ◽  
Author(s):  
Owen C. Fenderson ◽  
W. Harry Everhart ◽  
Kenneth M. Muth
Keyword(s):  
Social Interaction ◽  
Atlantic Salmon ◽  
Feeding Behavior ◽  
Salmo Salar ◽  
Social Dominance ◽  
Food Preference ◽  
Feeding Rate ◽  
Feeding Time ◽  
Feeding Rates ◽  
Wild Salmon

When hatchery-reared and wild landlocked Atlantic salmon (Salmo salar) parr of the same age and size were permitted to compete for social dominance and for food in aquaria, twice as many hatchery salmon attained dominance as wild salmon. Dominant hatchery salmon also showed a higher intensity of aggressiveness than dominant wild salmon, displaying a higher and more variable mean nipping rate. Socially dominant salmon ate more food per fish than subordinates, but there were no statistically significant differences in feeding rate between dominant hatchery and dominant wild salmon, or between subordinate hatchery and subordinate wild salmon.Hatchery salmon displayed lower feeding rates than wild salmon when they were held in separate compartments of an aquarium and compared at three temperatures. This difference in feeding rate probably was not a reflection of differences in adaptation to temperature or food preference, but, rather, was the result of interference with feeding caused by the more intense social interaction among hatchery fish.It is suggested that high levels of aggressiveness may contribute to mortalities of hatchery-reared salmon planted in streams because of loss of feeding time, excessive use of energy, and increased exposure to predators.

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