scholarly journals Automatic genome segmentation with HMM-ANN hybrid models

2015 ◽  
Author(s):  
Li Shen

AbstractWe consider the problem of automatic genome segmentation (AGS) that aims to assign discrete labels to all genomic regions based on multiple ChIP-seq samples. We propose to use a hybrid model that combines a hidden Markov model (HMM) with an artificial neural network (ANN) to overcome the weaknesses of a standard HMM. Our contributions are threefold: first, we benchmark two approaches to generate targets for ANN training on an example dataset; second, we investigate many different ANN models to identify the ones with best predictions on chromatin states; third, we test different hyper-parameters and discuss how they affect the machine learning algorithms’ performance. We find our best performing models to beat two pervious state-of-the-art methods for AGS by large margins.

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Marwah Sattar Hanoon ◽  
Ali Najah Ahmed ◽  
Nur’atiah Zaini ◽  
Arif Razzaq ◽  
Pavitra Kumar ◽  
...  

AbstractAccurately predicting meteorological parameters such as air temperature and humidity plays a crucial role in air quality management. This study proposes different machine learning algorithms: Gradient Boosting Tree (G.B.T.), Random forest (R.F.), Linear regression (LR) and different artificial neural network (ANN) architectures (multi-layered perceptron, radial basis function) for prediction of such as air temperature (T) and relative humidity (Rh). Daily data over 24 years for Kula Terengganu station were obtained from the Malaysia Meteorological Department. Results showed that MLP-NN performs well among the others in predicting daily T and Rh with R of 0.7132 and 0.633, respectively. However, in monthly prediction T also MLP-NN model provided closer standards deviation to actual value and can be used to predict monthly T with R 0.8462. Whereas in prediction monthly Rh, the RBF-NN model's efficiency was higher than other models with R of 0.7113. To validate the performance of the trained both artificial neural network (ANN) architectures MLP-NN and RBF-NN, both were applied to an unseen data set from observation data in the region. The results indicated that on either architecture of ANN, there is good potential to predict daily and monthly T and Rh values with an acceptable range of accuracy.


2021 ◽  
Author(s):  
DEVIN NIELSEN ◽  
TYLER LOTT ◽  
SOM DUTTA ◽  
JUHYEONG LEE

In this study, three artificial neural network (ANN) models are developed with back propagation (BP) optimization algorithms to predict various lightning damage modes in carbon/epoxy laminates. The proposed ANN models use three input variables associated with lightning waveform parameters (i.e., the peak current amplitude, rising time, and decaying time) to predict fiber damage, matrix damage, and through-thickness damage in the composites. The data used for training and testing the networks was actual lightning damage data collected from peer-reviewed published literature. Various BP training algorithms and network architecture configurations (i.e., data splitting, the number of neurons in a hidden layer, and the number of hidden layers) have been tested to improve the performance of the neural networks. Among the various BP algorithms considered, the Bayesian regularization back propagation (BRBP) showed the overall best performance in lightning damage prediction. When using the BRBP algorithm, as expected, the greater the fraction of the collected data that is allocated to the training dataset, the better the network is trained. In addition, the optimal ANN architecture was found to have a single hidden layer with 20 neurons. The ANN models proposed in this work may prove useful in preliminary assessments of lightning damage and reduce the number of expensive experimental lightning tests.


Author(s):  
Arunaben Prahladbhai Gurjar ◽  
Shitalben Bhagubhai Patel

The new era of the world uses artificial intelligence (AI) and machine learning. The combination of AI and machine learning is called artificial neural network (ANN). Artificial neural network can be used as hardware or software-based components. Different topology and learning algorithms are used in artificial neural networks. Artificial neural network works similarly to the functionality of the human nervous system. ANN is working as a nonlinear computing model based on activities performed by human brain such as classification, prediction, decision making, visualization just by considering previous experience. ANN is used to solve complex, hard-to-manage problems by accruing knowledge about the environment. There are different types of artificial neural networks available in machine learning. All types of artificial neural networks work based of mathematical operation and require a set of parameters to get results. This chapter gives overview on the various types of neural networks like feed forward, recurrent, feedback, classification-predication.


2022 ◽  
pp. 1-30
Author(s):  
Arunaben Prahladbhai Gurjar ◽  
Shitalben Bhagubhai Patel

The new era of the world uses artificial intelligence (AI) and machine learning. The combination of AI and machine learning is called artificial neural network (ANN). Artificial neural network can be used as hardware or software-based components. Different topology and learning algorithms are used in artificial neural networks. Artificial neural network works similarly to the functionality of the human nervous system. ANN is working as a nonlinear computing model based on activities performed by human brain such as classification, prediction, decision making, visualization just by considering previous experience. ANN is used to solve complex, hard-to-manage problems by accruing knowledge about the environment. There are different types of artificial neural networks available in machine learning. All types of artificial neural networks work based of mathematical operation and require a set of parameters to get results. This chapter gives overview on the various types of neural networks like feed forward, recurrent, feedback, classification-predication.


2010 ◽  
Vol 458 ◽  
pp. 212-217 ◽  
Author(s):  
Chang Feng Yuan ◽  
Wan Lei Wang ◽  
Yan Chen

Product agile customization design is an effective technological measure to win the customers and improve development efficiency. It needs designer to determine product structure quickly according to customer’s customized requirements. In this paper, a novel design method of product agile customization is presented by integrating rough set (RS) theory and artificial neural network (ANN) in the design process. In the method, design demands are reduced so as to form effective decision conditions by applying RS, and on that basis ANN models between design demands of different design stages and corresponding product structures are established so as to determine product structural styles quickly by applying ANN. Finally, this method is applied to the general schematic design process of a roll plate machine’s customization, and its validity is verified.


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