scholarly journals Gated Coupling of Dopamine and Neuropeptide Signaling Underlies Perceptual Processing of Appetitive Odors in Drosophila

2017 ◽  
Author(s):  
Yuhan Pu ◽  
Melissa Megan Masserant Palombo ◽  
Yiwen Zhang ◽  
Ping Shen

AbstractHow olfactory stimuli are perceived as meaningful cues for specific appetitive drives remains poorly understood. Here we show that despite their enormous diversity, Drosophila larvae can discriminatively respond to food-related odor stimuli based on both qualitative and quantitative properties. Perceptual processing of food scents takes place in a neural circuit comprising four dopamine (DA) neurons and a neuropeptide F (NPF) neuron per brain hemisphere. Furthermore, these DA neurons integrate and compress inputs from second-order olfactory neurons into one-dimensional DA signals, while the downstream NPF neuron assigns appetitive significance to limited DA outputs via a D1-type DA receptor (DoplR1)-mediated gating mechanism. Finally, Dop1R, along with a Gβ13F/Irk2-mediated inhibitory and a Gαs-mediated excitatory pathway, underlie a binary precision tuning apparatus that restricts the excitatory response of NPF neurons to DA inputs that fall within an optimum range. Our findings provide fresh molecular and cellular insights into cognitive processing of olfactory cues.


Author(s):  
Shenglan Yuan ◽  
Dirk Blömker ◽  
Jinqiao Duan

This work is devoted to investigating stochastic turbulence for the fluid flow in one-dimensional viscous Burgers equation perturbed by Lévy space-time white noise with the periodic boundary condition. We rigorously discuss the regularity of solutions and their statistical quantities in this stochastic dynamical system. The quantities include moment estimate, structure function and energy spectrum of the turbulent velocity field. Furthermore, we provide qualitative and quantitative properties of the stochastic Burgers equation when the kinematic viscosity [Formula: see text] tends towards zero. The inviscid limit describes the strong stochastic turbulence.



2011 ◽  
Vol 2011 ◽  
pp. 1-24 ◽  
Author(s):  
Bin Zheng ◽  
Qinghua Feng

Some new Volterra-Fredholm-type discrete inequalities in two independent variables are established, which provide a handy tool in the study of qualitative and quantitative properties of solutions of certain difference equations. The established results extend some known results in the literature.



Cerâmica ◽  
2018 ◽  
Vol 64 (370) ◽  
pp. 176-182 ◽  
Author(s):  
C. I. Torres ◽  
N. M. Rendtorff ◽  
M. Cipollone ◽  
E. F. Aglietti ◽  
G. Suárez

Abstract The results of qualitative and quantitative properties of clay based ceramic are presented in this work. Four different shaping methods and sintering temperatures were used to understand their influence in the final properties of a ceramic material formulated using kaolinite clay and calcined alumina. This material can be used as a structural ceramic for different applications, and there is no pre-established relation between the forming method and the final sintered properties. Forming methods used to prepare the samples were uniaxial pressing (a batch process that allows application in dry samples), extruding (a continuous process that requires moisture), slip casting (a process that allows to shape complex ceramic ware), and lamination (a batch process that requires moisture). Sintering temperatures were in the range of 1100 and 1400 °C. In order to compare how properties behave as the shaping method and sintering temperature change, textural properties, shrinkage, porosimetry, phase composition and mechanical strength were evaluated and analyzed. Scanning electron microscopy and microtomography were employed for analyzing and comparing the developed microstructures. Differences in the resulting properties are explained in terms of the developed crystalline phases and microstructure.



2021 ◽  
Vol 845 (1) ◽  
pp. 012063
Author(s):  
OA Nikolskay ◽  
A V Solonkin ◽  
E N Kikteva

Abstract Sweet cherry is a thermophilic and whimsical crop that reacts painfully to unfavorable meteorological conditions, such as frost, drought or high humidity in the air and soil. At the same time, this crop requires a uniform supply of heat and moisture during the growing season. In the climatic conditions of the Volgograd region, stressful situations often arise that can partially or completely reduce the yield of fruit crops, especially those introduced to our region from other regions. To reduce the risk of losing the yield of fruit plantations, including sweet cherry, it is necessary to pay special attention to the choice of the variety, as well as the rootstock on which this variety is grafted. The publication presents the results of studying the influence of rootstocks on the qualitative and quantitative indicators of sweet cherry fruits, such as taste, weight, uniformity, color, and productivity. According to the results of the study in the field (in the garden), varietal-rootstock combinations were identified that have one-dimensional, crack-resistant, large fruits, while maintaining high and stable productivity. According to the results of research, it was found that the rootstock affects not only the strength of growth and the shape of the crown, but also the quality of the fruit. The most dependent of the studied varieties on the type of rootstock is Euphoria, the lowest weight of berries was observed on the rootstock VSL-1. At the same time, this rootstock has a higher percentage of resistance to cracking of the fruit. Based on the conducted research, it can be concluded that with the help of rootstock, it becomes possible to influence the quality indicators of fruits.



Author(s):  
Samantha Hughes ◽  
Tansu Celikel

From single-cell organisms to complex neural networks, all evolved to provide control solutions to generate context and goal-specific actions. Neural circuits performing sensorimotor computation to drive navigation employ inhibitory control as a gating mechanism, as they hierarchically transform (multi)sensory information into motor actions. Here, we focus on this literature to critically discuss the proposition that prominent inhibitory projections form sensorimotor circuits. After reviewing the neural circuits of navigation across various invertebrate species, we argue that with increased neural circuit complexity and the emergence of parallel computations inhibitory circuits acquire new functions. The contribution of inhibitory neurotransmission for navigation goes beyond shaping the communication that drives motor neurons, instead, include encoding of emergent sensorimotor representations. A mechanistic understanding of the neural circuits performing sensorimotor computations in invertebrates will unravel the minimum circuit requirements driving adaptive navigation.



Author(s):  
Martin Shubik ◽  
Eric Smith

In this chapter the two features of uncertainty and the variability of the velocity of money are considered. Both of these are fundamental to considering the more subtle features of a monetary economy. They are interlinked and both add further complex features to the information, perception and control mechanisms of modern monetary systems. There has been an explosive development in the study of both the qualitative and quantitative properties of risk. The power of careful modeling and sophisticated stochastic analysis has already shown itself in the context of the stockmarket and other financial markets, but as the various qualitative aspects of risk are being uncovered and made well-defined, the scope of a useful econo-physics stretches far beyond the confines of the dynamics of paper traded on paper in the financial markets to the broad control mechanisms of the economy as a whole.



Nematology ◽  
2006 ◽  
Vol 8 (6) ◽  
pp. 869-879 ◽  
Author(s):  
Kazuyoshi Futai ◽  
Natsumi Kanzaki ◽  
Yuko Takeuchi

AbstractPine wilt disease causes ecological and economic damage in Japanese pine forests in spite of intensive effort to protect them from the pine wood nematode, Bursaphelenchus xylophilus. Pine trees infected with B. xylophilus emit a characteristic bouquet of volatile compounds bioactive to the vector beetle of the nematode, Monochamus alternatus, and potentially affecting symptom development inside the trees. To investigate the qualitative and quantitative properties of volatile compounds in the field, we profiled the volatile emissions in two Japanese black pine stands, one naturally suffering from pine wilt disease and the other artificially inoculated with B. xylophilus. In both pine stands, the emission of some terpenoids from the infected trees such as (−)-α-pinene, began to increase in summer, overlapping the oviposition season of the vector beetle, but peaked in the summer and autumn. These data suggest that the beetles may not necessarily depend on the tremendous quantity of volatiles alone when they search for suitable trees on which to oviposit.



Endocrinology ◽  
2010 ◽  
Vol 152 (2) ◽  
pp. 595-606 ◽  
Author(s):  
Wilbur P. Williams ◽  
Stephan G. Jarjisian ◽  
Jens D. Mikkelsen ◽  
Lance J. Kriegsfeld

Abstract In spontaneously ovulating rodents, the preovulatory LH surge is initiated on the day of proestrus by a timed, stimulatory signal originating from the circadian clock in the suprachiasmatic nucleus (SCN). The present studies explored whether kisspeptin is part of the essential neural circuit linking the SCN to the GnRH system to stimulate ovulation in Syrian hamsters (Mesocricetus auratus). Kisspeptin neurons exhibit an estrogen-dependent, daily pattern of cellular activity consistent with a role in the circadian control of the LH surge. The SCN targets kisspeptin neurons via vasopressinergic (AVP), but not vasoactive intestinal polypeptide-ergic, projections. Because AVP administration can only stimulate the LH surge during a restricted time of day, we examined the possibility that the response to AVP is gated at the level of kisspeptin and/or GnRH neurons. Kisspeptin and GnRH activation were assessed after the administration of AVP during the morning (when AVP is incapable of initiating the LH surge) and the afternoon (when AVP injections stimulate the LH surge). Kisspeptin, but not GnRH, cellular activity was up-regulated after morning injections of AVP, suggesting that time-dependent sensitivity to SCN signaling is gated within GnRH but not kisspeptin neurons. In support of this possibility, we found that the GnRH system exhibits pronounced daily changes in sensitivity to kisspeptin stimulation, with maximal sensitivity in the afternoon. Together these studies reveal a novel mechanism of ovulatory control with interactions among the circadian system, kisspeptin signaling, and a GnRH gating mechanism of control.



2013 ◽  
Vol 141 (3) ◽  
pp. 2440-2449 ◽  
Author(s):  
Abdollah Ghasemi Pirbalouti ◽  
Elahe Mahdad ◽  
Lyle Craker


1984 ◽  
Vol 288 ◽  
pp. 253-275 ◽  
Author(s):  
Andrzej Stolyhwo ◽  
Henry Colin ◽  
Michel Martin ◽  
Georges Guiochon


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