scholarly journals Influence of physical activity and sleep duration on the retinal and choroidal structure in diabetic patients: An SS-OCT study

Author(s):  
Sen Liu ◽  
Wei Wang ◽  
Zihan Qiu ◽  
Miao He ◽  
Wenyong Huang

ABSTRACTPurposeTo assess the association between physical activity, sleep duration, sitting time, and alterations of posterior segment structures with swept-source optical coherence tomography (SS-OCT).MethodsPatients with diabetic retinopathy (DR) were recruited, and diabetic patients without retinopathy (non-DR) who matched for age and duration of diabetes were used as control. The physical activity, siting time, and sleep duration were obtained by using standardized questionnaire. OCT parameters included: retinal nerve fibre layer (RNFL) thickness, ganglion cell inner plexiform layer (GC-IPL) thickness, retinal thickness, and choroidal thickness (CT). Linear regression was conducted to analyse the association.ResultsEach group included 116 diabetic patients. Average macular CT was positively correlated with metabolic equivalents (MET) only in the DR group, independent of age, gender, and other potential confounding factors (β = 1.163, P = 0.006). Average macular CT was also positively correlated with sleep duration only in the non-DR group, independent of age, gender, and other potential confounding factors (β = 10.54, P = 0.031). No correlation was found between MET, sleep duration, and other OCT parameters. Sitting time was not significantly correlated with OCT parameters either.ConclusionsPhysical activity and sleep duration are both positively correlated with macular choroidal thickness; this suggests that more time in physical activity and sleep benefit the retina, while there was no association between sedentary time and OCT parameters. Further studies are warranted to clarify the underlying mechanisms and the role of physical activity and sleep in CT alterations and DR.

2021 ◽  
pp. 0145482X2110466
Author(s):  
Justin A. Haegele ◽  
Xihe Zhu ◽  
Sean Healy

Introduction: This study sought to examine: (a) the associations between physical activity, sedentary time, and sleep duration, as discrete behaviors, with depression among adults with visual impairments; and (b) the impact of meeting none, one, two, or three of the guidelines for these behaviors on depression among adults with visual impairments. Materials: One hundred eighty-two ( Mage = 44.8) adults with visual impairments, recruited via email through two visual impairment organizations in the United States, completed the International Physical Activity Questionnaire–Short Form, a sleep duration question, the Major Depression Inventory, and a demographic questionnaire. Based on results from the questionnaires, dichotomous variables for meeting or not meeting physical activity, sleep, and sitting guidelines were created. Data were analyzed using three components: a descriptive analysis, Pearson product-moment correlation analyses, and hierarchical regression analyses. Results: Overall, 14.8% of participants were categorized as having some degree of depression. Meeting the sleep guideline was a significant negative predictor of depression scores in the hierarchical regression analyses. The number of guidelines met was a negative predictor for depression score controlling for other variables. Discussion: Adequate sleep, as well as meeting all three guidelines synergistically, was meaningful in influencing depression among this population. The current study’s results should prompt the continued examination of health-behaviors among adults with visual impairment using a more holistic 24-hour activity cycle framework. Implications for practitioners: This study supports the utilization of multi-behavioral interventions to reduce the risk of depression by enhancing physical activity and sleep, while reducing sitting time, among this population.


2015 ◽  
Vol 57 (3) ◽  
pp. 321-328 ◽  
Author(s):  
Diana Guertler ◽  
Corneel Vandelanotte ◽  
Camille Short ◽  
Stephanie Alley ◽  
Stephanie Schoeppe ◽  
...  

2020 ◽  
Vol 6 (1) ◽  
pp. e000661 ◽  
Author(s):  
Edvard H Sagelv ◽  
Laila A Hopstock ◽  
Jonas Johansson ◽  
Bjørge H Hansen ◽  
Soren Brage ◽  
...  

ObjectivesWe compared the ability of physical activity and sitting time questionnaires (PAQ) for ranking individuals versus continuous volume calculations (physical activity level (PAL), metabolic equivalents of task (MET), sitting hours) against accelerometry measured physical activity as our criterion.MethodsParticipants in a cohort from the Tromsø Study completed three questionnaires; (1) The Saltin-Grimby Physical Activity Level Scale (SGPALS) (n=4040); (2) The Physical Activity Frequency, Intensity and Duration (PAFID) questionnaire (n=5902)) calculated as MET-hours·week-1 and (3) The International Physical Activity questionnaire (IPAQ) short-form sitting question (n=4896). We validated the questionnaires against the following accelerometry (Actigraph wGT3X-BT) estimates: vector magnitude counts per minute, steps∙day-1, time (minutes·day-1) in sedentary behaviour, light physical activity, moderate and vigorous physical activity (MVPA) non-bouted and ≥10 min bouted MVPA.ResultsRanking of physical activity according to the SGPALS and quartiles (Q) of MET-hours∙week-1 from the PAFID were both positively associated with accelerometry estimates of physical activity (p<0.001) but correlations with accelerometry estimates were weak (SGPALS (PAL): r=0.11 to 0.26, p<0.001) and weak-to-moderate (PAFID: r=0.39 to 0.44, p<0.01). There was 1 hour of accelerometry measured sedentary time from Q1 to Q4 in the IPAQ sitting question (p<0.001) and also weak correlations (r=0.22, p<0.01).ConclusionRanking of physical activity levels measured with PAQs appears to have higher validity than energy expenditure calculations. Self-reported sedentary time poorly reflects accelerometry measured sedentary time. These two PAQs can be used for ranking individuals into different physical activity categories supporting previous studies using these instruments when assessing associations with health outcomes.


2020 ◽  
Vol 78 (1) ◽  
Author(s):  
Pei-Lin Tzeng ◽  
Chien-Yu Lin ◽  
Ting-Fu Lai ◽  
Wan-Chi Huang ◽  
Evonne Pien ◽  
...  

Abstract Background Lifestyle behaviors are modifiable factors that can provide information for designing intervention strategies for sarcopenia. The present study aimed to identify the relationships between a range of daily lifestyle behaviors and sarcopenia risks among older adults. Methods A nationwide telephone-based survey targeting older adults (≥65 years) was performed in Taiwan. Data based on self-reported daily lifestyle behaviors (food selection, physical activity, sitting time, and sleep duration), the presence or absence of sarcopenia (measured by SARC-F), and personal characteristics were obtained. Binary logistic regression models were applied. Results A total of 1068 older adults participated in this survey. In the adjusted model, older adults who selected unbalanced foods (odds ratio [OR] = 1.93, 95% confidence interval [CI] = 1.12–3.34), engaged in insufficient physical activity (OR = 5.14, 95% CI = 3.04–8.70), and sat for longer periods of time (OR = 1.98, 95% CI = 1.09–3.59) were more likely to have higher risks of sarcopenia. No significant association was observed for sleep duration. Conclusions The results of this study highlight that, among health behaviors, an unbalanced food selection (six nutrients), not meeting physical activity recommendations (150 min/week), and a higher sitting time (≥7 h/day) were risk factors for sarcopenia among older adults. Intervention programs for sarcopenia prevention in older adults should focus on promoting balanced food selection, sufficient physical activity, and reduced sitting time.


2016 ◽  
Vol 13 (8) ◽  
pp. 830-837 ◽  
Author(s):  
Tilahun Nigatu Haregu ◽  
Christopher Khayeka-Wandabwa ◽  
Nicholas Ngomi ◽  
Samuel Oti ◽  
Thaddaeus Egondi ◽  
...  

Background:Insufficient physical activity and sedentary behavior are key risk factors for the emergence of noncommunicable diseases in the sub-Saharan African setting. Given the limited evidence base, research is required to understand the trends.Objectives:This study describes the patterns of physical activity and sedentary behavior in a large sample of urban slum residents in Nairobi, Kenya.Methods:We used data collected from 5190 study participants as part of cardiovascular disease risk assessment. Data were collected about work-, transport-, and recreation-related physical activity as well as sitting and sleeping time. Using time spent on each type of physical activity and respective metabolic equivalents (METs), patterns of physical activity and associated factors were evaluated using descriptive statistics, Pearson correlations, and logistic regression.Results:Nearly 50% of the study population was involved in work-related physical activities, whereas only 6.3% was involved in recreation-related physical activities. Involvement in physical activities decreased with age, and 17.4% had <600 MET-minutes per week. Higher sitting time was associated with insufficient physical activity. There were substantial gender differences in the time spent for physical activity.Conclusions:Given the positive relationship between insufficient physical activity and sedentary behavior, complementary interventions that improve physical activity and at the same time reduce sitting time are needed.


2020 ◽  
Author(s):  
Sen Liu ◽  
Wei Wang ◽  
Yan Tan ◽  
Miao He ◽  
Lanhua Wang ◽  
...  

AbstractPurposeTo investigate the association between the estimated glomerular filtration rate (eGFR) and peripapillary choroidal thickness (pCT) and retinal nerve fibre layer (pRNFL) thickness in diabetic patients by using swept-source optical coherence tomography (SS-OCT).MethodsOcular treatment-naïve patients with type 2 diabetes mellitus registered in the community health system in Guangzhou, China were recruited to participate in this prospective cross-sectional study. The eGFR was determined using the Xiangya formula, and the renal function was categorized into non-chronic kidney disease (non-CKD), mild CKD, and moderate to severe CKD (MS-CKD) according to the guidelines. The pCT and pRNFL thicknesses at 12 o’clock were obtained using a SS-OCT by a circular scan with a diameter of 3.4 mm centring on the optic nerve head, and the data from only one eye in each patient were used.ResultsThis study included 1,408 diabetic patients, with a mean age of 64.4±7.8 years. The average pCT decreased with renal function deterioration, with 126.0 μm ± 58.0 μm for non-CKD, 112.0 μm ± 51.2 μm for mild CKD and 71.0μm ± 22.9 μm for MS-CKD, respectively (P<0.001). The pCT was found to be significantly thinner in CKD patients in all quadrantes (P < 0.05 in all regions) with the exception of the inferior quadrant, and the average pCT was positively correlated with eGFR (β = 0.3, 95%CI = 0.0 to 0.6, p = 0.021) after making adjustments for other factors. The pRNFL thickness in the nasal quadrant was significantly reduced in patients with CKD, and pRNFL thickness was positively correlated with eGFR (β = 0.1, 95%CI = 0.0-0.2, p = 0.009) after adjusting for other factors.ConclusionImpaired renal function was associated with a reduction of pCT and pRNFL thickness in patients with type 2 diabetes. The measurement of pCT and pRNFL may provide additional information for predicting renal impairment.


2020 ◽  
Author(s):  
Deyuan Zhou ◽  
Wei Wang ◽  
Rouxi Zhou ◽  
Miao He ◽  
Xia Gong ◽  
...  

AbstractPurposeTo determine whether there was a change in the fundus of the eye in diabetic patients without retinopathy after insulin therapy.MethodsThe diabetic patients without retinopathy were included in this study. A swept-source optical coherence tomography/angiography (SS-OCT/A) was used to obtain the measurements of macular retinal nerve fibre layer (mRNFL) thickness, ganglion cell-inner plexiform layer (GC-IPL) thickness, retinal thickness (RT), macular choroidal thickness (MCT), peripapillary retinal nerve fibre layer (pRNFL) thickness, peripapillary choroidal thickness (PCT), and perfused vascular density (PVD). Univariable and multivariable regression analyses were performed to explore the influence of insulin use on measurements of OCT/A.ResultsA total of 1140 patients used insulin (using group), and 126 patients did not use insulin (without group). The average MCT of the using group was 171.3±67.8 μm, which was thinner than that in the without group (190.2±74.7 μm) (P=0.012). The average PVD of the using group (48.0±2.1 μm) was less than that in the without group (48.7±2.1 μm) (P<0.001). After adjusting for age, gender, axial length, duration, HbA1c, systolic blood pressure, diastolic blood pressure, cholesterol, serum creatinine, insulin use was significantly associated with thinner MCT (beta=-16.12μm; 95%CI:-29.42, −2.81μm; P= 0.018) and lower PVD (beta=-0.79; 95%CI: −1.22, −0.36; P<0.001).ConclusionThe use of insulin by diabetic patients without retinopathy might decrease the MCT and PVD compared to patients who did not use insulin, which helps to better understanding the role of insulin use on higher risk for diabetic retinopathy.


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