scholarly journals The impact of COVID-19 on patients with asthma

2020 ◽  
Author(s):  
Jose Luis Izquierdo ◽  
Carlos Almonacid ◽  
Yolanda Gonzalez ◽  
Carlos Del Rio-Bermudez ◽  
Julio Ancochea ◽  
...  
Keyword(s):  
Hospital Admission ◽  
Inhaled Corticosteroids ◽  
Big Data Analytics ◽  
Related Factors ◽  
Asthmatic Patients ◽  
Admission Rates ◽  
Increased Risk ◽  
Predominantly Female ◽  
The Impact ◽  
Diabetes And Obesity

Background: From the onset of the COVID-19 pandemic, an association between the severity of COVID-19 and the presence of certain medical chronic conditions has been suggested. However, unlike influenza and other viruses, the burden of the disease in patients with asthma has been less evident. Objective: This study aims at a better understanding of the burden of COVID-19 in patients with asthma and the impact of asthma, its related comorbidities, and treatment on the prognosis of COVID-19. Methods: We analyzed clinical data from patients with asthma from January 1st to May 10th, 2020 using big data analytics and artificial intelligence through the SAVANA Manager clinical platform. Results: Out of 71,192 patients with asthma, 1,006 (1.41%) suffered from COVID-19. Compared to asthmatic individuals without COVID-19, patients with asthma and COVID-19 were significantly older (55 vs. 42 years), predominantly female (66% vs. 59%), had higher prevalence of hypertension, dyslipidemias, diabetes, and obesity, and smoked more frequently. Contrarily, allergy-related factors such as rhinitis and eczema were less frequent in asthmatic patients with COVID-19 (P < .001). Higher prevalence of hypertension, dyslipidemia, diabetes, and obesity was also confirmed in those patients with asthma and COVID-19 who required hospital admission. The percentage of individuals using inhaled corticosteroids (ICS) was lower in patients who required hospitalization due to COVID-19, as compared to non-hospitalized patients (48.3% vs. 61.5%; OR: 0.58: 95% CI 0.44-0.77). During the study period, 865 (1.21%) patients with asthma were being treated with biologics. Although these patients showed increased severity and more comorbidities at the ear, nose, and throat (ENT) level, their hospital admission rates due to COVID-19 were relatively low (0.23%). COVID-19 increased inpatient mortality in asthmatic patients (2.29% vs 0.54%; OR 2.29: 95% CI 4.35-6.66). Conclusion: Our results indicate that the number of COVID-19 cases in patients with asthma has been low, although higher than the observed in the general population. Patients with asthma and COVID-19 were older and were at increased risk due to comorbidity-related factors. ICS and biologics are generally safe and may be associated with a protective effect against severe COVID-19 infection.

scholarly journals The Impact of COVID-19 on Patients with Asthma

2020 ◽  
pp. 2003142 ◽  
Author(s):  
José Luis Izquierdo ◽  
Carlos Almonacid ◽  
Yolanda González ◽  
Carlos Del Rio-Bermúdez ◽  
Julio Ancochea ◽  
...  
Keyword(s):  
Disease Burden ◽  
Inhaled Corticosteroids ◽  
Big Data Analytics ◽  
Related Factors ◽  
Asthmatic Patients ◽  
Hospitalised Patients ◽  
Increased Risk ◽  
Predominantly Female ◽  
The Impact ◽  
Diabetes And Obesity

BackgroundAn association between the severity of COVID-19 and the presence of certain chronic conditions has been suggested. However, unlike influenza and other viruses, the disease burden in patients with asthma has been less evident.ObjectiveTo understand the impact of COVID-19 in patients with asthma.MethodsUsing big data analytics and artificial intelligence through the SAVANA Manager® clinical platform, we analysed clinical data from patients with asthma from January 1st to May 10th, 2020.ResultsOut of 71 182 patients with asthma, 1006 (1.41%) suffered from COVID-19. Compared to asthmatic individuals without COVID-19, patients with asthma and COVID-19 were significantly older (55 versus 42 years), predominantly female (66% versus 59%), smoked more frequently, and had higher prevalence of hypertension, dyslipidemias, diabetes, and obesity. Allergy-related factors such as rhinitis and eczema were less common in asthmatic patients with COVID-19 (p<.001). Higher prevalence of these comorbidities was also observed in patients with COVID-19 who required hospital admission. The use of inhaled corticosteroids (ICS) was lower in patients who required hospitalisation due to COVID-19, as compared to non-hospitalised patients (48.3% versus 61.5%; OR: 0.58: 95% CI 0.44–0.77). Although patients treated with biologics (n=865; 1.21%) showed increased severity and more comorbidities at the ENT level, COVID-19-related hospitalisations in these patients were relatively low (0.23%).ConclusionPatients with asthma and COVID-19 were older and at increased risk due to comorbidity-related factors. ICS and biologics are generally safe and may be associated with a protective effect against severe COVID-19 infection.

The Most Dangerous Game: A Review of Head and Neck Injuries in American Football and Rugby

2022 ◽  
pp. 194338752110734
Author(s):  
Jordan Richardson ◽  
Dani Stanbouly ◽  
Harrison Moynihan ◽  
Renée M. Reynolds ◽  
Matthew J. Recker ◽  
...  
Keyword(s):  
Emergency Department ◽  
Hospital Admission ◽  
Head And Neck ◽  
Predictor Variable ◽  
American Football ◽  
Outcome Variable ◽  
Neck Injuries ◽  
Injury Surveillance System ◽  
Admission Rates ◽  
Increased Risk

Study Design The investigators designed and implemented a 20-year cross-sectional study using the National Electronic Injury Surveillance System database. Objective The purpose of this study is to estimate and compare hospital admission (danger) rates between rugby and football of those who presented to the emergency department with head and neck injuries after playing these sports. Methods The primary predictor variable was sport played. The primary outcome variable was danger, measured by hospital admission rates. Results Over the past 20 years, there has been a trend of decreasing incidence of injuries presenting to the emergency department in both sports. There was no difference in the rate of hospital admission when comparing football and rugby (OR, 1.2; P = .1). Male gender was associated with an increased risk of admission. Other variables associated with hospital admission included white racial group, injury taking place in the fall, being either young (15–24 years old) or senior (65 years of age and over), and being injured at school or at a sport/recreational facility. Conclusions There is no difference in danger as measured by admission rates between American football and rugby. There exists, however, several variables that are associated with admission when sustaining injury to the head and neck, when playing these two sports.

scholarly journals Parenting and Future Anxiety: The Impact of Having a Child with Developmental Disabilities

2019 ◽  
Vol 16 (4) ◽  
pp. 668 ◽  
Author(s):  
Anna Bujnowska ◽  
Celestino Rodríguez ◽  
Trinidad García ◽  
Débora Areces ◽  
Nigel Marsh
Keyword(s):  
Developmental Disabilities ◽  
Autism Spectrum ◽  
General Level ◽  
Older Children ◽  
Future Health ◽  
Related Factors ◽  
Professional Career ◽  
Increased Risk ◽  
Lower Education ◽  
The Impact

This study examined differences in future anxiety (FA) among mothers and fathers of children with and without developmental disabilities (DD), and it also analyzed differences in FA within the group of parents of children with DD taking into consideration parent-related factors and child-related factors. A group of 167 parents of children with DD were compared to a group of 103 parents of children with typical development. The group with DD included children with autism spectrum disorders, sensory disorders, and intellectual disability. Parents completed the Future Anxiety Scale-FAS1. Mothers of children with DD had a higher general level of FA than fathers of children with and without DD. Mothers of children with DD reported higher anxiety about their future health and the meaning of their future life than fathers of children with DD. For parents of children with DD, those with lower education, male children, and older children reported higher FA. The group at risk of highest general FA are mothers of children with DD, especially those without a professional career. Similarly, parents of teenagers and/or sons with DD are at increased risk of FA.

Impact of Frailty and Sociodemographic Factors on Hospital Admission From an Emergency Department Observation Unit

2016 ◽  
Vol 32 (3) ◽  
pp. 299-306 ◽  
Author(s):  
Michael J. Zdradzinski ◽  
Michael P. Phelan ◽  
Sharon E. Mace
Keyword(s):  
Emergency Department ◽  
Hospital Admission ◽  
Multivariable Analysis ◽  
Disability Insurance ◽  
Sociodemographic Factors ◽  
College Graduation ◽  
Screening Criteria ◽  
Katz Index ◽  
Increased Risk ◽  
The Impact

Understanding factors associated with an increased risk of hospital admission from emergency department (ED) observation units (OUs) could be valuable in disposition decisions. To evaluate the impact of frailty and sociodemographic factors (SDFs) on admission risk, patients in an ED OU were surveyed. Survey measures included SDFs, social habits, and frailty measured by the Katz Index of Independence in Activities of Daily Living. Of 306 surveyed, 18% were admitted and 82% were discharged. Demographics were similar between groups. More admitted patients responded positively to the Katz Index (28% vs 13%, P = .007; odds ratio = 2.73; 95% CI = 1.35-5.51). College graduation and current employment favored the discharge group, while admitted patients were more likely to receive Social Security disability insurance. Frailty remained associated with admission on multivariable analysis. Frailty, disability insurance, and lower education are predictors of admission from an OU and could serve as screening criteria in disposition decisions.

scholarly journals Early Psychological Impact of the COVID-19 Pandemic in Brazil: A National Survey

2020 ◽  
Vol 9 (9) ◽  
pp. 2976 ◽  
Author(s):  
Juliana Alvares Duarte Bonini Campos ◽  
Bianca Gonzalez Martins ◽  
Lucas Arrais Campos ◽  
João Marôco ◽  
Rayya Ahmed Saadiq ◽  
...  
Keyword(s):  
Mental Health ◽  
Online Survey ◽  
Psychological Symptoms ◽  
Psychological Impact ◽  
Validity And Reliability ◽  
Related Factors ◽  
Event Scale ◽  
Increased Risk ◽  
Population Demographic ◽  
The Impact

Background: Isolation measures used to contain epidemics generate social interaction restrictions and impose changes in routines of the public that increase negative psychological outcomes. Anxiety and depression are the most common symptoms. Objective: To evaluate the mental health of the Brazilian population during the SARs-CoV-2 pandemic and its relationship with demographic and health characteristics. Methods: Adults from all Brazilian States participated (n = 12,196; women: 69.8%, mean age = 35.2 years). The Depression, Anxiety and Stress Scale, and the Impact of Event Scale–revised were used (online survey). Data validity and reliability were verified by confirmatory factor analysis and ordinal alpha coefficient. The probability of presenting psychological symptoms was calculated by multiple logistic regression and odds ratio (OR) (0 = without symptoms, 1 = with mild, moderate, and severe levels of symptoms). Results: High prevalence of depression (61.3%), anxiety (44.2%), stress (50.8%), and psychological impact (54.9%) due to the isolation experienced from the pandemic was found. Younger individuals (OR = 1.58–3.58), those that felt unsafe (OR = 1.75–2.92), with a previous diagnosis of mental health (OR = 1.72–2.64) and/or had general health problems before the pandemic (OR = 1.17–1.51), who noticed changes in their mental state due to the pandemic context (OR = 2.53–9.07), and excessively exposed to the news (OR = 1.19–2.18) were at increased risk of developing symptoms. Women (OR = 1.35–1.65) and those with lower economic status (OR = 1.38–2.69) were more likely to develop psychological symptoms. Lower educational levels increased the likelihood of depressive (OR = 1.03–1.34) and intrusive symptoms (OR = 1.09–1.51). Conclusions: The pandemic and related factors can have a high impact on the mental health of the population. Demographic characteristics can influence the occurrence of psychological symptoms.

scholarly journals Understanding the impact of systemic lupus erythematosus on work amongst South Asian people in the UK: An explorative qualitative study

Lupus ◽  
2021 ◽  
pp. 096120332110228
Author(s):  
Mandeep Ubhi ◽  
Shirish Dubey ◽  
Caroline Gordon ◽  
Tochukwu Adizie ◽  
Tom Sheeran ◽  
...  
Keyword(s):  
South Asian ◽  
Lupus Erythematosus ◽  
Cultural Barriers ◽  
Structured Interviews ◽  
Ability To Work ◽  
Related Factors ◽  
Work Related ◽  
Increased Risk ◽  
The Uk ◽  
The Impact

SLE has a range of fluctuating symptoms affecting individuals and their ability to work. Although South Asian (SA) patients are at increased risk of developing SLE there is limited knowledge of the impact on employment for these patients in the UK. Understanding ethnicity and disease-specific issues are important to ensure patients are adequately supported at work. Semi-structured interviews were conducted with patients of SA origin to explore how SLE impacted on their employment. Thematic analysis was used to analyse the data which are reported following COREQ guidelines. Ten patients (8 female; 2 male) were recruited from three rheumatology centres in the UK and interviewed between November 2019 and March 2020. Patients were from Indian (n = 8) or Pakistani (n = 2) origin and worked in a range of employment sectors. Four themes emerged from the data: (1) Disease related factors; (2) Employment related factors; (3) Cultural and interpersonal factors impacting on work ability; (4) Recommendations for improvement. Patients’ ability to work was affected by variable work-related support from their hospital clinicians, low awareness of SLE and variable support from their employers, and cultural barriers in their communities that could affect levels of family support received. These findings highlight the need for additional support for SA patients with SLE in the workplace.

Impact of the 2009-2014 economic crisis on suicide attempts and self-harm in Portugal

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
V Pinheiro ◽  
B Nunes ◽  
S Pereira da Silva ◽  
C Caetano
Keyword(s):  
Hospital Admission ◽  
Economic Crisis ◽  
Suicide Attempts ◽  
Admission Rate ◽  
Sudden Increase ◽  
Hospital Admission Rate ◽  
Crisis Period ◽  
Increased Risk ◽  
Self Harm ◽  
The Impact

Abstract Background Following the worldwide economic crisis of 2008, studies have found an increased risk for self-harm and suicide attempts, many of which need hospital care. There is no research in Portugal on the matter. Therefore, our goal was to estimate the impact of the Portuguese economic crisis of 2009-2014 on the hospital admission rates by attempted suicide and self-harm in Portugal. Methods A retrospective ecological study, with an interrupted time series analysis of hospital admissions by suicide attempts (data from the national Hospital Mobility Database) in mainland Portugal, between 2003 and 2014, was performed. Resident population data over 15 years old was retrieved from the National Statistics Institute. Poisson regression models were used to compare rates and trends before (2003-2008) and during (2009-2014) the Portuguese economic crisis. All rates were adjusted for seasonality. Results A total of 35,077 hospital admission episodes by suicide attempt were retrieved. The mean admission rate was 2.947 per 100 000 inhabitants per month before the crisis, falling to 2.798 during the crisis period. Before the crisis, the total admission rate was decreasing 1% per year. After the crisis erupted, there was a level change, with a sudden increase of 7.9%. The suicide and self-harm admission rate, after 2008, was constant and approximately 38.8% higher than expected if the earlier trend had continued. Conclusions There was an increase in the total hospital admission rate by suicide attempts and self-harm during the economic crisis period in Portugal, when compared to the previous period. Key messages Economic crisis can pose considerable suicide risks. Urgent action is needed to prevent economic crisis leading to additional suicides.

scholarly journals The association between mother’s alcohol consumption during pregnancy and their child’s educational attainment and risk of hospital admission by age 14

2019 ◽  
Vol 4 (3) ◽  
Author(s):  
Amrita Bandyopadhyay ◽  
Sinead Brophy ◽  
Simon Moore ◽  
Ashley Akbari ◽  
Shantini Paranjothy ◽  
...  
Keyword(s):  
Alcohol Consumption ◽  
Alcohol Use ◽  
Educational Attainment ◽  
Hospital Admission ◽  
Cox Regression ◽  
Developmental Problems ◽  
Emergency Hospital ◽  
Emergency Hospital Admission ◽  
Increased Risk ◽  
The Impact

Background Heavy alcohol consumption by mothers during pregnancy is associated with developmental problems in their children. However, the impact of light to moderate consumption on the long-term health and educational attainment up to adolescence has not been established. Main Aim To investigate the association between mother’s alcohol use during pregnancy and health and educational attainment of their children up to age 14 years. Methods Millennium Cohort Study (MCS) children in Wales (1,838), with parental consent, were record-linked to emergency hospital admission data between birth and 14 years (1,795) and National Curriculum Key Stage-Three (KS3) (1,645) records within the Secure Anonymised Information Linkage (SAIL) Databank. Mother’s self-reported alcohol use during pregnancy was classified into a) abstain; b) light (1 - 2 units per week/occasion, 1 unit = 8g ethanol)); c) moderate (3 - 6 units per week/3-5 units per occasion) and d) heavy (> 6, dropped due to a paucity of data). Cox regression estimated the risk of emergency hospital admission and multivariate linear regression models estimated the difference in KS3 scores by exposure group. Results 71% of mothers abstained, 24% were light drinkers and 5% moderate. Light drinking was associated with children’s lower risk of emergency hospital admission (HR = 0.85, 95% CI 0.75 - 0.97) and better KS3 scores (β = 0.14, 95% CI 0.05 - 0.23) by age 14 years, when compared to abstaining mothers. Children of mothers who drank moderately had a comparable risk of emergency hospital admission (HR = 1.07, 95% CI 0.79 - 1.46) and a better KS3 score (β = 0.30, 95% CI 0.11 - 0.49), compared to abstaining mothers. Conclusion Consumption during pregnancy of 1-2 units of alcohol per week/occasion was neither associated with an increased risk of emergency hospital admission nor poor academic attainment in children up to 14 years of age.

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