scholarly journals Modeling of leptospirosis outbreaks in relation to hydroclimatic variables in the northeast of Argentina

Author(s):  
Andrea Alejandra Gomez ◽  
Maria Soledad Lopez ◽  
Gabriela Viviana Muller ◽  
Leonardo Rafael Lopez ◽  
Walter Sione ◽  
...  

The transmission of leptospirosis is conditioned by climatic variables. In northeastern Argentina leptospirosis outbreaks occur mainly in coincidence with periods of abundant precipitation and high hydrometric level. A Susceptible Infectious Recovered Epidemiological Model (SIR) is proposed, which incorporates hydroclimatic variables for the three most populated cities in the area (Santa Fe, Parana and Rosario), between 2009 and 2018. Results obtained by solving the proposed SIR model for the 2010 outbreaks are in good agreement with the actual data, capturing the dynamics of the leptospirosis outbreak wave. However, the model does not perform very well when isolated cases appear outside the outbreak periods, probably due to non-climatic factors not explicitly considered in the present version of the model. Nevertheless, the dynamic modeling of infectious diseases considering hydroclimatic variables constitutes a climatic service for the public health system, not yet available in Argentina.

2021 ◽  
Vol 13 (2) ◽  
pp. 19-28
Author(s):  
Amelia BUCUR ◽  

The mathematical study of epidemics and their management has been performed for many years, however, in the last few years, new models have been published. Public health is considered very important and has to be monitored, as it is permanently under risk due to the appearance of even more types of microorganisms. Compartmental models, such as exponential models, SI, SIS, SIR, SEIRS, SEIAR, MESIR models, other generalized SIR models were and still are remarkable for studying the spread of an epidemic and for their simulations in software such as MATLAB, Maple, GLEAMviz, etc. The paper has two main objectives: a. to present new simulations in Maple and GLEAMviz for the spread of COVID-19; b. to suggest a generalization of the SIR model for analyzing the spread of COVID-19 and a simulation of it in GLEAMviz. The conclusions are that, generally, mathematical models show a value of a reproduction threshold, which can be used to forecast whether the pandemic is the increasing or decreasing phase, and that mathematical models and simulations in various programs facilitate the improvement of methods of analysis of an epidemic situation and the management of the public health system.


2015 ◽  
Vol 18 (3) ◽  
pp. A224
Author(s):  
J.A. Turri ◽  
L.B. Haddad ◽  
W. Andrauss ◽  
L.A. D’Albuquerque ◽  
M.A. Diniz

Author(s):  
Paulo Gabriel Santos Campos de Siqueira ◽  
Alexandre Calumbi Antunes de Oliveira ◽  
Heitor Oliveira Duarte ◽  
Márcio das Chagas Moura

We have developed a probabilistic model to quantify the risks of COVID-19 explosion in Brazil, the epicenter of COVID-19 in Latin America. By explosion, we mean an excessive number of new infections that would overload the public health system. We made predictions from July 12th to Oct 10th, 2020 for various containment strategies, including business as usual, stay at home (SAH) for young and elderly, flight restrictions among regions, gradual resumption of business and the compulsory wearing of masks. They indicate that: if a SAH strategy were sustained, there would be a negligible risk of explosion and the public health system would not be overloaded. For the other containment strategies, the scenario that combines the gradual resumption of business with the mandatory wearing of masks would be the most effective, reducing risk to considerable category. Should this strategy is applied together with the investment in more Intensive Care Unit beds, risk could be reduced to negligible levels. A sensitivity analysis sustained that risks would be negligible if SAH measures were adopted thoroughly.


2021 ◽  
Vol 15 ◽  
Author(s):  
Graciela Lopez de Degani ◽  
Leandro Duarte ◽  
Julia Ismael ◽  
Laura Martinez ◽  
Florencia López

Author(s):  
Clea Adas Saliba Garbin ◽  
Bruno Wakayama ◽  
Tânia Adas Saliba ◽  
Orlando Adas Saliba Junior ◽  
Artênio José Ísper Garbin

2021 ◽  
Author(s):  
Gajanan Sapkal ◽  
Pragya Yadav ◽  
Raches Ella ◽  
Priya Abraham ◽  
Deepak Patil ◽  
...  

The emergence of new SARS-CoV-2 variants has been a serious threat to the public health system and vaccination program. The variant of concerns have been the under investigation for their neutralizing potential against the currently available COVID-19 vaccines. Here, we have determined the neutralization efficacy of B.1.1.28.2 variant with the convalescent sera of individuals with natural infection and BBV152 vaccination. The two-dose vaccine regimen significantly boosted the IgG titer and neutralizing efficacy against both B.1.1.28.2 and D614G variants compared to that seen with natural infection. The study demonstrated 1.92 and 1.09 fold reductions in the neutralizing titer against B.1.1.28.2 variant in comparison with prototype D614G variant with sera of vaccine recipients and natural infection respectively.


2011 ◽  
Vol 52 (1/3) ◽  
pp. 33-37
Author(s):  
Clarissa Fatturi Parolo ◽  
Aline Macarevich ◽  
Juliana Jobim Jardim ◽  
Marisa Maltz

Purpose: To compare the restorative material used in the treatment of posterior teeth taught and performed in two Dental Schools (UFRGS and ULBRA) and in 8 basic health units (BHU) from the Public Health System in Porto Alegre, Brazil. Materials and methods: Data referring the teaching of restorative procedures using amalgam (AM) or resin (R) were obtained through the analysis of patient’s files and questionnaires applied to final year dental students. Information regarding restorative procedures at BHU was obtained through patient’s records and a questionnaire applied to the dentists. The type of restorative material used in both BHU and Dental Schools were compared by chi-square test. Results: At UFRGS, 327 restorations were performed, 78.28% R and 21.72% AM, and at ULBRA 366 restorations, 92.63% R and 7.37% AM. At BHU, 1664 restorations were performed (35.93% R and 64.07% AM). A major proportion of AM restorations was performed in the Public Health Service in comparison to both Dental Schools, in which resin restorations prevailed (p=0.000). Conclusion: The change from AM to R in the dental material choice for posterior teeth at Dental Schools was not followed by the Public Health System, where the AM is still widely used in posterior teeth.


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