scholarly journals The role of cell geometry and cell-cell communication in gradient sensing

2021 ◽  
Author(s):  
Jonathan Fiorentino ◽  
Antonio Scialdone
Keyword(s):  
Mathematical Models ◽  
Long Range ◽  
Cell Communication ◽  
Cell Number ◽  
Cellular Communication ◽  
Cellular Systems ◽  
Nearest Neighbour ◽  
Gradient Sensing ◽  
Epithelial Tissues ◽  
Long Range Communication

Cells can measure shallow gradients of external signals to initiate and accomplish a migration or a morphogenetic process. Recently, starting from mathematical models like the local-excitation global-inhibition (LEGI) model and with the support of empirical evidence, it has been proposed that cellular communication improves the measurement of an external gradient. However, the mathematical models that have been used have over-simplified geometries (e.g., they are uni-dimensional) or assumptions about cellular communication, which limit the possibility to analyze the gradient sensing ability of more complex cellular systems. Here, we generalize the existing models to study the effects on gradient sensing of cell number, geometry and of long- versus short-range cellular communication in 2D systems representing epithelial tissues. We find that increasing the cell number can be detrimental for gradient sensing when the communication is weak and limited to nearest neighbour cells, while it is beneficial when there is long-range communication. We also find that, with long-range communication, the gradient sensing ability improves for tissues with more disordered geometries; on the other hand, an ordered structure with mostly hexagonal cells is advantageous with nearest neighbour communication. Our results considerably extend the current models of gradient sensing by epithelial tissues, making a step further toward predicting the mechanism of communication and its putative mediator in many biological processes.

scholarly journals Gradient sensing via cell communication

2021 ◽  
Vol 103 (2) ◽  
Author(s):  
Dallas Foster ◽  
Brian Frost-LaPlante ◽  
Collin Victor ◽  
Juan M. Restrepo
Keyword(s):  
Cell Communication ◽  
Gradient Sensing

Development of the Drosophila olfactory sense organs utilizes cell-cell interactions as well as lineage

Development ◽  
1997 ◽  
Vol 124 (3) ◽  
pp. 703-712 ◽  
Author(s):  
G.V. Reddy ◽  
B. Gupta ◽  
K. Ray ◽  
V. Rodrigues
Keyword(s):  
Cell Communication ◽  
Cell Number ◽  
Temperature Sensitive ◽  
Sense Organs ◽  
Notch Activity ◽  
Helix Loop Helix ◽  
Olfactory Sense ◽  
Sensitive Allele ◽  
Selection Of ◽  
Cell Cell

We have examined the mechanisms underlying the development of the olfactory sense organs on the third segment of the antenna of Drosophila. Our studies suggest that a novel developmental strategy is employed. Specification of the founder or precursor cell is not governed by the genes of the achaete-scute complex. Another basic helix-loop-helix encoding gene, atonal, is essential for determination of only a subset of the sensilla types--the sensilla coeloconica. Therefore, we predict the existence of additional proneural genes for the selection of sensilla trichoidea and sensilla basiconica. The choice of a founder cell from the presumed proneural domain is regulated by Notch activity. Soon after delamination of the founder cell, two to three additional neighboring cells also take on a sensory fate and these cells together form a presensillum cluster. The selection of neighbors does not occur when endocytosis is blocked using a temperature sensitive allele of shibire, thus suggesting that cell-cell communication is required for this step. The cells of the cluster divide once before terminal differentiation which is influenced by Notch activity. The final cell number within each sensillum is controlled by programmed cell death.

Fishermen Rescue Mission

2021 ◽  
Vol 9 (9) ◽  
pp. 1544-1548
Author(s):  
Ajai Prasad Thampi
Keyword(s):  
Long Range ◽  
Rescue Mission ◽  
Dangerous Situation ◽  
Current Location ◽  
Floating Objects ◽  
Long Range Communication

Abstract: The basic idea of this project is to save the life of fishermen at sea. We do this by installing a module in the fisherman’s life jacket. This module will be a transmitter which can transmit its current location. This module is made to be a floating module. Which is also waterproof. The person in the dangerous situation can press the button and the transmitter starts transmitting the location. The data is then transferred to the receiver via a network built by WLAN module which is also made by us. The WLAN module consists of the transmitter and the receiver and acts as repeater stations. These transmitters and receivers also contain the LoRa module. The LoRa module is Incorporated because of its long range communication specifications. The repeater station is placed buoy the help of buoys. Buoys are floating objects which are then anchored to make them stationary. The receiver is a portable one and dynamically we can get the location of the transmitter. Hence we can locate the person and then rescue them Keywords: LoRa, WLAN, GPS module,

Biogas Plant Digital Transformation Using Edge-Computing Batteryless and Free of Maintenance Atex Iot Powered by Heat

2021 ◽  
Author(s):  
Raul Aragones Ortiz ◽  
Roger Nicolas Alegret ◽  
Maria Oliver Parera ◽  
Joan Oliver Malagelada ◽  
Roger Malet Munté ◽  
...  
Keyword(s):  
Energy Harvesting ◽  
Long Range ◽  
Ecological Footprint ◽  
Communication Protocols ◽  
Digital Transformation ◽  
Biogas Plant ◽  
Edge Computing ◽  
Innovative Technology ◽  
Environmental Friendly ◽  
Long Range Communication

Abstract Current industries leave a big ecological footprint that needs to be reduced to preserve our resources. For it, big industries are leading new researches to move to more environmental-friendly technologies. In this paper we explain an innovative technology which has the ability to introduce edge-computing in the node in combination with energy harvesting, which allows the device to work without the need of batteries. Also, as all the computations are performed in the node, it allows the use of long-range communication protocols. To demonstrate the behavior of the technology, the paper also presents two cases of use in facilities.

scholarly journals Bulk-edge correspondence and long-range hopping in the topological plasmonic chain

Nanophotonics ◽  
2019 ◽  
Vol 8 (8) ◽  
pp. 1337-1347 ◽  
Author(s):  
Simon R. Pocock ◽  
Paloma A. Huidobro ◽  
Vincenzo Giannini
Keyword(s):  
Long Range ◽  
Metallic Nanoparticles ◽  
Nearest Neighbour ◽  
Edge States ◽  
Physical Treatment ◽  
Bulk Properties ◽  
One Dimensional ◽  
Measure Of Symmetry ◽  
Dipolar System ◽  
Desirable Trait

AbstractThe existence of topologically protected edge modes is often cited as a highly desirable trait of topological insulators. However, these edge states are not always present. A realistic physical treatment of long-range hopping in a one-dimensional dipolar system can break the symmetry that protects the edge modes without affecting the bulk topological number, leading to a breakdown in bulk-edge correspondence (BEC). Hence, it is important to gain a better understanding of where and how this occurs, as well as how to measure it. Here we examine the behaviour of the bulk and edge modes in a dimerised chain of metallic nanoparticles and in a simpler non-Hermitian next-nearest-neighbour model to provide some insights into the phenomena of bulk-edge breakdown. We construct BEC phase diagrams for the simpler case and use these ideas to devise a measure of symmetry-breaking for the plasmonic system based on its bulk properties. This provides a parameter regime in which BEC is preserved in the topological plasmonic chain, as well as a framework for assessing this phenomenon in other systems.

scholarly journals Sound Design for Vocalizations: Quality in the Woods, Consistency in the Fields

The Condor ◽  
2000 ◽  
Vol 102 (1) ◽  
pp. 81-92 ◽  
Author(s):  
Timothy J. Brown ◽  
Paul Handford
Keyword(s):  
Long Range ◽  
Amplitude Modulation ◽  
Carrier Frequency ◽  
Sound Design ◽  
Habitat Types ◽  
Acoustic Adaptation ◽  
Acoustic Adaptation Hypothesis ◽  
Closed Habitat ◽  
Long Range Communication ◽  
Low Rate

AbstractThe acoustic adaptation hypothesis (AAH) predicts that vocalizations intended for unambiguous long range communication should possess amplitude modulation (AM) characteristics such that the temporal patterning of amplitude degrades less than alternative patterns during transmission through native habitat. The specific predictions are that open habitat signals should be structured as rapid AM trills, whereas closed habitat signals should be structured as low-rate AM tonal whistles. To investigate the benefit of trill- and whistle-structured signals in open and closed habitats, respectively, a high and low carrier frequency set of four synthetic signals which ranged from rapid AM trills to low rate AM whistles were transmitted 3 hours after sunrise through five different habitat types ranging from closed mature forest to open grassland. Results indicate that, on average, whistles degrade less than trills in both habitats. Trills benefit in open habitats through their tendency to be received with a more consistent quality than whistles. Such differences in transmission consistency among AM patterns are not found in closed habitats. While not degrading less on average, lower frequency signals are received with a more consistent quality than are higher frequency signals of the same AM structure, in both open and closed habitats.

Conceivable Bioremediation Techniques Based on Quorum Sensing

2013 ◽  
Vol 295-298 ◽  
pp. 39-44 ◽  
Author(s):  
Nan Qing Liao ◽  
Hao Ming Li
Keyword(s):  
Heavy Metal ◽  
Quorum Sensing ◽  
Contaminated Soils ◽  
Genetic Basis ◽  
Cellular Communication ◽  
Cellular Systems ◽  
Reversible Process ◽  
Wide Range

Quorum sensing(QS) is a mechanism of microbes to coordinate their activities, which allows them to function as multi-cellular systems. Recently, many researches have proved that the engineered QS system have a wide range of applications such as bioremediation of oil and heavy metal contaminated soils, and prevention of biofouling. Here we review the function of QS signals produced by bacteria, and the principle of enhancing degradative capacities of microbe. Specifically, we describe how QS system regulate the formation and dispersion of biofilms, which are reversible process that biofilms may be generated and removed as desired. The development of strategies to disrupt and manipulate QS are also implicated. Cells can be engineered to secrete QS signals to affect the behavior of neighboring cells in a consortium via engineered cellular communication. The complete genetic basis of QS may be used to control these communities of associated cells for bioremediation applications.

Sign in / Sign up

Export Citation Format

Share Document