scholarly journals Prevalence and time trend of congenital heart defects: a registry-based study in Iran

2021 ◽  
Author(s):  
Hossein Molapour ◽  
Saeed Dastgiri ◽  
Elham Davtalabesmaeili
Keyword(s):  
Congenital Heart Defects ◽  
Congenital Anomalies ◽  
Prevalence Rate ◽  
Congenital Heart ◽  
Time Trend ◽  
Heart Defects ◽  
Live Births ◽  
Registry System ◽  
Methodological Improvement ◽  
Northwest Of Iran

Introduction: Conclusion Congenital heart defects (CHD) are one of the most common types of congenital anomalies affecting one percent of births every year. The aim of this study was to report the prevalence and time trend of CHD in the northwest of Iran between 2000 and 2019. Methods: Since 2000, infants born with birth defects have been registered in Tabriz Registry of Congenital Anomalies (TRoCA). For this study, the information and data of newborns with CHD (1084) were collected using the TRoCA registry system. Results: Over two decades the prevalence rate of CHD in the northwest of Iran was 3.7 per 1000 live births (95 percent CI: 34.9 to 39.4). The prevalence rate of CHD during the first decade (2000-09) and the second (2010-19) were estimated 2.8 (95 percent CI: 2.5 to 2.9) and 5.9 (95 percent CI: 5.4 to 6.4) per 1000 live births, respectively. Conclusion: The prevalence rate of CHD in Iran showed an increasing trend indicating methodological improvement in the facilities and diagnosis techniques. It would therefore seem essential to concentrate on the primary prevention activities to reduce the burden of these defects. Keywords: Congenital heart defects, Prevalence, Congenital heart anomalies, Epidemiology

Prevalence and Pattern of Congenital Anomalies in a Tertiary Hospital in Central Vietnam

2019 ◽  
Vol 66 (2) ◽  
pp. 187-193
Author(s):  
Hoang Thi Nam Giang ◽  
Susanne Bechtold-Dalla Pozza ◽  
Sarah Ulrich ◽  
Le Khac Linh ◽  
Hoang Thi Tran
Keyword(s):  
Congenital Heart Defects ◽  
Congenital Anomalies ◽  
Congenital Heart ◽  
Heart Defects ◽  
Tertiary Hospital ◽  
Cross Sectional Study ◽  
Common Type ◽  
Cross Sectional ◽  
Live Births ◽  
Central Vietnam

Abstract Background Burden and pattern of congenital anomalies are insufficiently reported in Vietnam. This study aims to determine the prevalence and pattern of congenital anomalies in neonates in a tertiary hospital in central Vietnam. Methods A prospective cross-sectional study recruited all newborns with congenital anomalies in Da Nang Hospital for Women and Children—where nearly 60% neonates in the city are delivered. Results Over a 1-year period, 551 out of 14 335 registered live births were found to have congenital anomalies, equivalent to an overall prevalence of 384.4 per 10 000 live births. Congenital heart defects were the most common type (52.3%) with the prevalence of 200.9 per 10 000 live births, followed by anomalies of musculoskeletal system, digestive system. Conclusions This study revealed a high prevalence of congenital anomalies with the most common type being congenital heart defects in central Vietnam compared to both higher income countries and resource-limited settings.

Out-of-hospital sudden cardiac arrest in children with congenital heart defects

2017 ◽  
Vol 103 (1) ◽  
pp. 57-60 ◽  
Author(s):  
Jarle Jortveit ◽  
Jakob Klcovansky ◽  
Gaute Døhlen ◽  
Leif Eskedal ◽  
Sigurd Birkeland ◽  
...  
Keyword(s):  
Cardiac Arrest ◽  
Congenital Heart Defects ◽  
Congenital Heart ◽  
Heart Defects ◽  
Sudden Cardiac Arrest ◽  
Supplementary Information ◽  
Clinical Registry ◽  
Birth Registry ◽  
Live Births ◽  
Hospital Cardiac Arrest

AimsOut-of-hospital sudden cardiac arrest (SCA) is a rare but devastating event in children and adolescents. The risk is assumed to be higher in children with congenital heart defects (CHDs) than in healthy individuals. The aim of the present study was to investigate the rate of and survival after out-of-hospital cardiac arrest in children 2–18 years old with CHDs.Methods and resultsData concerning all live births in Norway between 1994 and 2009 were retrieved from the Medical Birth Registry of Norway, the patient administrative systems at all hospitals in Norway, the Oslo University Hospital’s Clinical Registry for Congenital Heart Defects and the Norwegian Cause of Death Registry. Survivors were followed through 2012, and supplementary information for the deceased children was retrieved from medical records at Norwegian hospitals. Among the 943 871 live births in Norway from 1994 to 2009, 11 272 (1.2%) children had a CHD. We identified 11 (0.1%) children 2–18 years old with CHDs who experienced out-of-hospital SCA. The estimated rate of out-of-hospital SCA in children 2–18 years old with CHD was 10 per 100 000 person-years. Early cardiopulmonary resuscitation was initiated in all patients. Three children survived.ConclusionsThe incidence of and survival after out-of-hospital SCA in children with CHDs were comparable to the reported rates in the general child population.

scholarly journals Palivizumab for prophylaxis of respiratory syncytial virus infections in preterm neonates

2017 ◽  
Vol 229 (05) ◽  
pp. 259-260
Author(s):  
Ludwig Gortner
Keyword(s):  
Respiratory Syncytial Virus ◽  
Congenital Heart Defects ◽  
Congenital Anomalies ◽  
Congenital Heart ◽  
Heart Defects ◽  
The United States ◽  
Preterm Neonates ◽  
Virus Infections ◽  
Number Of Children ◽  
Syncytial Virus

Recent data indicate that the number of children cared for respiratory syncytial virus (RSV) infections in hospitals is in the range of 50,000 to 100,000 per year in the United States 3. Major risk factors include apart from prematurity specifically below 29 weeks, congenital heart defects, Down syndrome and further congenital anomalies. The American Academy of Pediatrics recommended in 2014 a restriction of Palivizumab prophylaxis to preterm infants of <29 weeks of gestation and those with a high-risk course postnatally and higher gestational ages apart from specific indications resulting from congenital anomalies including congenital heart defects 1.

Frequency and spectrum of congenital heart defects among live births in Germany

2011 ◽  
Vol 100 (12) ◽  
pp. 1111-1117 ◽  
Author(s):  
Gerda Schwedler ◽  
Angelika Lindinger ◽  
Peter E. Lange ◽  
Ulrich Sax ◽  
Julianna Olchvary ◽  
...  
Keyword(s):  
Congenital Heart Defects ◽  
Congenital Heart ◽  
Heart Defects ◽  
Live Births

scholarly journals The incidence of congenital heart defects in the world regarding the severity of the defect

2016 ◽  
Vol 73 (2) ◽  
pp. 159-164 ◽  
Author(s):  
Vesna Miranovic
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart Defects ◽  
Congenital Heart ◽  
Heart Defects ◽  
Methodological Approach ◽  
Live Births ◽  
Significant Difference ◽  
The World

Bacground/Aim. Congenital heart defects (CHDs) are structural or functional abnormalities of the heart present at birth even if they are detected much later. Their importance lies in the fact that, depending on the severity, they change the quality of life, and may be life threating. In addition, we should not ignore the high costs of treating people with congenital heart disease. The aim of this study was to analyze the incidence of congenital heart disease in relation to the severity in the world based on the available literature. Methods. All the available literature on the incidence of CHD cases regarding the severity of CHD published from 1955 to 2012 was analyzed. The researcher was able to read the titles and abstracts of 128 papers on the subject. Due to methodological inconsistency, 117 of the papers were rejected. Based on the criteria of reliability, availability and comparability, our analysis included 11 studies testing CHD incidence regarding the severity of the defect conducted all over the world. The Yates' ?2-test was used to compare the observed incidences. Results. The frequency of severe congenital heart defects, ranged from 0.414 to 2.3/1,000 live births, the incidence of moderate congenital heart defects from 0.43 to 2.6/1,000 live births while in the group of minor congenital heart defects the incidence ranged from 0.99 to 10.3/1000 live births. There were no statistically significant differences in the incidence of mild, moderate and severe CHDs. Conclusion. The results obtained studying of the available data suggest that no statistically significant difference in the incidence of mild, moderate and severe congenital heart defects. A universal methodological approach to the incidence of CHD is essential.

scholarly journals A Case of Situs Ambiguous and Complex Cardiac Defect Presenting as Fetal Hydrops

2017 ◽  
Vol 02 (02) ◽  
pp. 060-063
Author(s):  
Shagun Aggarwal
Keyword(s):  
Case Report ◽  
Congenital Heart Defects ◽  
Congenital Heart ◽  
Heart Defects ◽  
Cardiac Defect ◽  
Fetal Hydrops ◽  
Cardiac Defects ◽  
Live Births ◽  
Situs Ambiguous ◽  
Laterality Defects

AbstractSitus ambiguous comprises of 3% of congenital heart defects and is present in at least 1 in 10,000 live births. Most cases diagnosed prenatally are associated with complex cardiac defects which can be detected by ultrasonography. This is a case report of a fetus presenting with hydrops, which was detected to have situs ambiguous, a complex cardiac defect and multiple laterality defects on autopsy.

scholarly journals Prevalence of Congenital Anomalies: A Community-Based Study in the Northwest of Iran

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Hossein Mashhadi Abdolahi ◽  
Mohammad Hassan Kargar Maher ◽  
Farzaneh Afsharnia ◽  
Saeed Dastgiri
Keyword(s):  
Birth Defects ◽  
Rural Areas ◽  
Congenital Anomalies ◽  
Prevalence Rate ◽  
Heart Diseases ◽  
Similar Rate ◽  
Western Region ◽  
Mortality And Morbidity ◽  
Live Births ◽  
Northwest Of Iran

Background. Congenital anomalies are responsible for a remarkable proportion of mortality and morbidity in newborns. The aim of this study was to document the epidemiological features of congenital anomalies in rural areas, northwest of Iran. Method. The study population included live births born between 2004 and 2012 in rural areas of Tabriz district. All health records of the children under 8 years were assessed retrospectively. Results. Of 22500 live births, 254 cases were identified with a primary diagnosis of congenital anomalies giving a prevalence rate of 112.89 per 10 000 births (95% CI: 99.08 to 126.69). Anomalies of the nervous system were the most common defects, accounting for 24% of birth defects followed by the heart diseases anomalies. The highest prevalence rate for birth defects was observed in the south-western region with 386 per 10 000 births (95% CI: 215 to 556) compared to the similar rate in the north-western region with 15 per 10 000 births (95% CI: −14 to 45). Conclusion. The considerable geographic disparities in the prevalence of congenital anomalies in the region might be attributed to the highly polluted industrial zone in the area (including air and water pollution, etc.). This needs further etiological investigations in the region.

scholarly journals Congenital Anomalies of the Kidney and Urinary Tract in Children with Congenital Heart Defects

2020 ◽  
Vol 45 (2) ◽  
pp. 307-313
Author(s):  
Dapeng Jiang ◽  
Qi Wang ◽  
Zhengzhou Shi ◽  
Jie Sun
Keyword(s):  
Urinary Tract ◽  
Congenital Heart Defects ◽  
Congenital Anomalies ◽  
Congenital Heart ◽  
Medical Center ◽  
Heart Defects ◽  
Clinical Manifestations ◽  
Number Of Patients ◽  
Significant Difference ◽  
History Of

Background/Aims: To investigate the incidence and clinical characteristics of congenital anomalies of the kidney and urinary tract (CAKUT) in children with congenital heart defects (CHD). Methods: We retrospectively analyzed the clinical data of children with CHD with CAKUT admitted to the Shanghai Children’s Medical Center affiliated with the Shanghai Jiao Tong University School of Medicine between September 2018 and March 2019. Patients underwent routine examinations for liver, kidney, and coagulation function, and urinary tract ultrasonography, and we summarized patients’ clinical manifestations and imaging abnormalities. Results: A total of 1,410 children with CHD were diagnosed and treated in our hospital. The total number of patients with abnormal urogenital systems was 104, and hydronephrosis was the most common abnormality, followed by vesicoureteral reflux and duplication of the kidney and ureter. The overall prevalence of CAKUT was 7.4%. There was no statistically significant difference for maternal age, sex, parity, gestational age, and history of medication during pregnancy between the patients with CAKUT and those without CAKUT. Conclusion: The incidence of CAKUT in our patients with CHD was significantly higher than that in the general population. We recommend urinary ultrasonography as a routine examination for children with CHD for early detection of CAKUT, to avoid missed diagnoses, and to initiate appropriate treatment.

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