scholarly journals Oxazepam and cognitive reappraisal: a randomised experiment

2019 ◽  
Author(s):  
Gustav Nilsonne ◽  
Sandra Tamm ◽  
Armita Golkar ◽  
Andreas Olsson ◽  
Karolina Sörman ◽  
...  
Keyword(s):  
Heart Rate ◽  
Skin Conductance ◽  
Emotional Regulation ◽  
Rating Scales ◽  
Preliminary Investigation ◽  
Cognitive Reappraisal ◽  
Emotional Valence ◽  
Reactivity Index ◽  
Anxiety State ◽  
Negative Valence

AbstractBackgroundCognitive reappraisal is a strategy for emotional regulation, important in the context of anxiety disorders. It is not known whether anxiolytic effects of benzodiazepines affect cognitive reappraisal.AimsWe aimed to investigate the effect of 25 mg oxazepam on cognitive reappraisal.MethodsIn a preliminary investigation, 33 healthy male volunteers were randomised to oxazepam or placebo, and then underwent an experiment where they were asked to use cognitive reappraisal to upregulate or downregulate their emotional response to images with negative or neutral emotional valence. We recorded unpleasantness ratings, skin conductance, superciliary corrugator muscle activity, and heart rate. Participants completed rating scales measuring empathy (Interpersonal Reactivity Index, IRI), anxiety (State-Trait Anxiety Inventory, STAI), alexithymia (Toronto Alexithymia Scale-20, TAS-20), and psychopathy (Psychopathy Personality Inventory-Revised, PPI-R).ResultsUpregulation to negative-valence images in the cognitive reappraisal task caused increased unpleasantness ratings, corrugator activity, and heart rate compared to downregulation. Upregulation to both negative- and neutral-valence images caused increased skin conductance responses. Oxazepam caused lower unpleasantness ratings to negative-valence stimuli, but did not interact with reappraisal instruction on any outcome. Self-rated trait empathy was associated with stronger responses to negative-valence stimuli, whereas self-rated psychopathic traits were associated with weaker responses to negative-valence stimuli.ConclusionsWhile 25 mg oxazepam caused lower unpleasantness ratings in response to negative-valence images, we did not observe an effect of 25 mg oxazepam on emotional reappraisal.

scholarly journals Oxazepam and cognitive reappraisal: A randomised experiment

PLoS ONE ◽  
2021 ◽  
Vol 16 (4) ◽  
pp. e0249065
Author(s):  
Gustav Nilsonne ◽  
Sandra Tamm ◽  
Armita Golkar ◽  
Andreas Olsson ◽  
Karolina Sörman ◽  
...  
Keyword(s):  
Heart Rate ◽  
Skin Conductance ◽  
Emotional Regulation ◽  
Rating Scales ◽  
Preliminary Investigation ◽  
Cognitive Reappraisal ◽  
Emotional Valence ◽  
Reactivity Index ◽  
Anxiety State ◽  
Negative Valence

Background Cognitive reappraisal is a strategy for emotional regulation, important in the context of anxiety disorders. It is not known whether anxiolytic effects of benzodiazepines affect cognitive reappraisal. Aims We aimed to investigate the effect of 25 mg oxazepam on cognitive reappraisal. Methods In a preliminary investigation, 33 healthy male volunteers were randomised to oxazepam or placebo, and then underwent an experiment where they were asked to use cognitive reappraisal to upregulate or downregulate their emotional response to images with negative or neutral emotional valence. We recorded unpleasantness ratings, skin conductance, superciliary corrugator muscle activity, and heart rate. Participants completed rating scales measuring empathy (Interpersonal Reactivity Index, IRI), anxiety (State-Trait Anxiety Inventory, STAI), alexithymia (Toronto Alexithymia Scale-20, TAS-20), and psychopathy (Psychopathy Personality Inventory-Revised, PPI-R). Results Upregulation to negative-valence images in the cognitive reappraisal task caused increased unpleasantness ratings, corrugator activity, and heart rate compared to downregulation. Upregulation to both negative- and neutral-valence images caused increased skin conductance responses. Oxazepam caused lower unpleasantness ratings to negative-valence stimuli, but did not interact with reappraisal instruction on any outcome. Self-rated trait empathy was associated with stronger responses to negative-valence stimuli, whereas self-rated psychopathic traits were associated with weaker responses to negative-valence stimuli. Conclusions While 25 mg oxazepam caused lower unpleasantness ratings in response to negative-valence images, we did not observe an effect of 25 mg oxazepam on cognitive reappraisal.

scholarly journals 0252 Influence of Sleep on Negative Social Judgment

SLEEP ◽  
2020 ◽  
Vol 43 (Supplement_1) ◽  
pp. A96-A96
Author(s):  
F E Corona ◽  
S C Mednick
Keyword(s):  
Heart Rate ◽  
Skin Conductance ◽  
Emotional Regulation ◽  
Psychosocial Stress ◽  
Emotional Reactivity ◽  
Heart Rate Response ◽  
Physiological Responses ◽  
Social Judgment ◽  
Judgment Task ◽  
Before And After

Abstract Introduction Sleep plays an important role in emotional regulation. Emotional regulation can be disrupted by psychosocial stress, including social judgment. It is not known whether sleep can regulate emotions arising from social judgment. The aim of this study is to determine if sleep can reduce emotional reactivity associated with negative social judgment. Methods On day one, subjects participated in a social judgment task (SJT) in the morning, followed by a nap or wake condition. Subjects’ physiological responses to social judgment task (skin conductance and heart rate) and mood were measured before and after the SJT, after the nap/wake condition, and once on day three. Results Mood ratings decreased after social judgment for all subjects, but increased following the nap intervention. Mood ratings improved after the 2 day delay. There were no changes in social status. Skin conductance during judgment decreased for subjects in nap condition, but not wake. After a 2 day delay, skin conductance decreased across subjects, with those in nap condition experiencing greater decrease. Heart rate response during social judgment exposure decreased only for those in nap group, with a 2 day delay showing decreased heart rate response across all subjects. Conclusion A nap directly following social judgment buffers negative response to the experience by decreasing emotional reactivity as measured by mood, skin conductance, and heart rate response. No differences were found between nappers and non-nappers on day three, suggesting that sleep benefits emotional reactivity associated with the stress of social judgment and that these benefits can happen with a nap or a night of sleep, more than a period of wake. Support University of California, Irvine.

The Effect of Searching Versus Surfing on Cognitive and Emotional Responses to Online News

2009 ◽  
Vol 21 (2) ◽  
pp. 49-59 ◽  
Author(s):  
Kevin Wise ◽  
Hyo Jung Kim ◽  
Jeesum Kim
Keyword(s):  
Heart Rate ◽  
Skin Conductance ◽  
Skin Conductance Level ◽  
Emotional Responses ◽  
Online News ◽  
Self Report ◽  
Mixed Design ◽  
Information Need ◽  
News Stories ◽  
Rate Acceleration

A mixed-design experiment was conducted to explore differences between searching and surfing on cognitive and emotional responses to online news. Ninety-two participants read three unpleasant news stories from a website. Half of the participants acquired their stories by searching, meaning they had a previous information need in mind. The other half of the participants acquired their stories by surfing, with no previous information need in mind. Heart rate, skin conductance, and corrugator activation were collected as measures of resource allocation, motivational activation, and unpleasantness, respectively, while participants read each story. Self-report valence and recognition accuracy were also measured. Stories acquired by searching elicited greater heart rate acceleration, skin conductance level, and corrugator activation during reading. These stories were rated as more unpleasant, and their details were recognized more accurately than similar stories that were acquired by surfing. Implications of these results for understanding how people process online media are discussed.

Lying and perception of lies by bilingual speakers

2019 ◽  
Vol 40 (05) ◽  
pp. 1313-1329 ◽  
Author(s):  
Nora Kreyßig ◽  
Agnieszka Ewa Krautz
Keyword(s):  
Second Language ◽  
Skin Conductance ◽  
Emotional Response ◽  
Native Language ◽  
Reading Aloud ◽  
Emotional Valence ◽  
Bilingual Speakers ◽  
Skin Conductance Responses ◽  
English Second Language ◽  
Task Requirements

AbstractMultiple studies on bilingualism and emotions have demonstrated that a native language carries greater emotional valence than the second language. This distinction appears to have consequences for other types of behavior, including lying. As bilingual lying has not been explored extensively, the current study investigated the psychophysiological differences between German (native language) and English (second language) in the lying process as well as in the perception of lies. The skin conductance responses of 26 bilinguals were measured during reading aloud true and false statements and listening to recorded correct and wrong assertions. The analysis revealed a lie effect, that is, statistically significant differences between valid and fictitious sentences. In addition, the values in German were higher compared to those in English, in accordance with the blunted emotional response account (Caldwell-Harris & Aycicegi-Dinn, 2009). Finally, the skin conductance responses were lower in the listening condition in comparison to the reading aloud. The results, however, are treated with caution given the fact that skin conductance monitoring does not allow assigning heightened reactivity of the skin to one exclusive cause. The responses may have been equally induced by the content of the statements, which prompted positive or negative associations in the participants’ minds or by the specific task requirements.

scholarly journals Stress Markers for Mental States and Biotypes of Depression and Anxiety: A Scoping Review and Preliminary Illustrative Analysis

2021 ◽  
Vol 5 ◽  
pp. 247054702110003
Author(s):  
Megan Chesnut ◽  
Sahar Harati ◽  
Pablo Paredes ◽  
Yasser Khan ◽  
Amir Foudeh ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Skin Conductance ◽  
Neural Circuit ◽  
Current Knowledge ◽  
Mental States ◽  
Classification Model ◽  
Depression And Anxiety ◽  
Stress Markers ◽  
Physiological Markers

Depression and anxiety disrupt daily function and their effects can be long-lasting and devastating, yet there are no established physiological indicators that can be used to predict onset, diagnose, or target treatments. In this review, we conceptualize depression and anxiety as maladaptive responses to repetitive stress. We provide an overview of the role of chronic stress in depression and anxiety and a review of current knowledge on objective stress indicators of depression and anxiety. We focused on cortisol, heart rate variability and skin conductance that have been well studied in depression and anxiety and implicated in clinical emotional states. A targeted PubMed search was undertaken prioritizing meta-analyses that have linked depression and anxiety to cortisol, heart rate variability and skin conductance. Consistent findings include reduced heart rate variability across depression and anxiety, reduced tonic and phasic skin conductance in depression, and elevated cortisol at different times of day and across the day in depression. We then provide a brief overview of neural circuit disruptions that characterize particular types of depression and anxiety. We also include an illustrative analysis using predictive models to determine how stress markers contribute to specific subgroups of symptoms and how neural circuits add meaningfully to this prediction. For this, we implemented a tree-based multi-class classification model with physiological markers of heart rate variability as predictors and four symptom subtypes, including normative mood, as target variables. We achieved 40% accuracy on the validation set. We then added the neural circuit measures into our predictor set to identify the combination of neural circuit dysfunctions and physiological markers that accurately predict each symptom subtype. Achieving 54% accuracy suggested a strong relationship between those neural-physiological predictors and the mental states that characterize each subtype. Further work to elucidate the complex relationships between physiological markers, neural circuit dysfunction and resulting symptoms would advance our understanding of the pathophysiological pathways underlying depression and anxiety.

scholarly journals Effectiveness of Hypnosis in Combination with Conventional Techniques of Behavior Management in Anxiety/Pain Reduction during Dental Anesthetic Infiltration

2017 ◽  
Vol 2017 ◽  
pp. 1-5 ◽  
Author(s):  
A. Ramírez-Carrasco ◽  
C. Butrón-Téllez Girón ◽  
O. Sanchez-Armass ◽  
M. Pierdant-Pérez
Keyword(s):  
Heart Rate ◽  
Skin Conductance ◽  
Pain Control ◽  
Behavior Management ◽  
Statistical Difference ◽  
Dental Treatment ◽  
Management Techniques ◽  
Conventional Behavior ◽  
Behavior Management Techniques ◽  
Experimental Group

Background and Objective. Anxiety/pain are experiences that make dental treatment difficult for children, especially during the time of anesthesia. Hypnosis is used in pediatric clinical situations to modify thinking, behavior, and perception as well as, recently, in dentistry; therefore the aim of this study was to evaluate the effectiveness of hypnosis combined with conventional behavior management techniques during infiltration anesthetic.Methods. Anxiety/pain were assessed with the FLACC scale during the anesthetic moment, as well as heart rate variability and skin conductance before and during the anesthetic moment, between the control and experimental group.Results. A marginal statistical difference (p=0.05) was found in the heart rate between baseline and anesthetic moment, being lower in the hypnosis group. No statistically significant differences were found with the FLACC scale or in the skin conductance (p>0.05).Conclusion. Hypnosis combined with conventional behavior management techniques decreases heart rate during anesthetic infiltration showing that there may be an improvement in anxiety/pain control through hypnotic therapy.

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