scholarly journals Evolution of Specialization in Dynamic Fluids

2019 ◽  
Author(s):  
Gurdip Uppal ◽  
Dervis Can Vural
Keyword(s):  
Niche Partitioning ◽  
Decay Rates ◽  
Physical Factors ◽  
Community Structures ◽  
Invasion Fitness ◽  
Physical Simulations ◽  
Diverse Community ◽  
Mechanical Factors ◽  
Evolution Of Specialization

AbstractPreviously we found mechanical factors involving diffusion and fluid shear promote evolution of social behavior in microbial populations Uppal and Vural (2018). Here, we extend this model to study the evolution of specialization using realistic physical simulations of bacteria that secrete two public goods in a dynamic fluid. Through this first principles approach, we find physical factors such as diffusion, flow patterns, and decay rates are as influential as fitness economics in governing the evolution of community structure, to the extent that when mechanical factors are taken into account, (1) Generalist communities can resist becoming specialists, despite the invasion fitness of specialization (2) Generalist and specialists can both resist cheaters despite the invasion fitness of free-riding. (3) Multiple community structures can coexist despite the opposing force of competitive exclusion. Our results emphasize the role of spatial assortment and physical forces on niche partitioning and the evolution of diverse community structures.

scholarly journals An Overview of the Role of Mechanical Stretching in the Progression of Lung Cancer

2021 ◽  
Vol 9 ◽  
Author(s):  
Fengying Gong ◽  
Yuchao Yang ◽  
Liangtao Wen ◽  
Congrong Wang ◽  
Jingjun Li ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Progression ◽  
Mechanical Load ◽  
Tumor Development ◽  
Physical Factors ◽  
Mechanical Factors ◽  
Tissue Characteristics ◽  
The Relationship ◽  
Mechanical Stretching

Cells and tissues in the human body are subjected to mechanical forces of varying degrees, such as tension or pressure. During tumorigenesis, physical factors, especially mechanical factors, are involved in tumor development. As lung tissue is influenced by movements associated with breathing, it is constantly subjected to cyclical stretching and retraction; therefore, lung cancer cells and lung cancer-associated fibroblasts (CAFs) are constantly exposed to mechanical load. Thus, to better explore the mechanisms involved in lung cancer progression, it is necessary to consider factors involved in cell mechanics, which may provide a more comprehensive analysis of tumorigenesis. The purpose of this review is: 1) to provide an overview of the anatomy and tissue characteristics of the lung and the presence of mechanical stimulation; 2) to summarize the role of mechanical stretching in the progression of lung cancer; and 3) to describe the relationship between mechanical stretching and the lung cancer microenvironment, especially CAFs.

scholarly journals The emerging role of mechanical and topographical factors in the development and treatment of nervous system disorders: dark and light sides of the force

2021 ◽  
Author(s):  
Natalia Bryniarska-Kubiak ◽  
Andrzej Kubiak ◽  
Małgorzata Lekka ◽  
Agnieszka Basta-Kaim
Keyword(s):  
Nervous System ◽  
Physical Factors ◽  
Nervous System Diseases ◽  
Therapeutic Approaches ◽  
System Disease ◽  
New Therapeutic Approaches ◽  
The Subject ◽  
Topographical Factors ◽  
New Treatment

AbstractNervous system diseases are the subject of intensive research due to their association with high mortality rates and their potential to cause irreversible disability. Most studies focus on targeting the biological factors related to disease pathogenesis, e.g. use of recombinant activator of plasminogen in the treatment of stroke. Nevertheless, multiple diseases such as Parkinson’s disease and Alzheimer’s disease still lack successful treatment. Recently, evidence has indicated that physical factors such as the mechanical properties of cells and tissue and topography play a crucial role in homeostasis as well as disease progression. This review aims to depict these factors’ roles in the progression of nervous system diseases and consequently discusses the possibility of new therapeutic approaches. The literature is reviewed to provide a deeper understanding of the roles played by physical factors in nervous system disease development to aid in the design of promising new treatment approaches. Graphic abstract

The role of physical factors in the complex therapy of patients with rheumatoid arthritis

1985 ◽  
Vol 66 (4) ◽  
pp. 318-318
Author(s):  
L. V. Chernetsova ◽  
A. G. Ibragimova
Keyword(s):  
Rheumatoid Arthritis ◽  
Comparative Analysis ◽  
Drug Therapy ◽  
Electromagnetic Waves ◽  
Physical Factors ◽  
Complex Therapy ◽  
Decimeter Range

The comparative analysis of treatment of 76 patients with rheumatoid arthritis using electromagnetic waves of the decimeter range and lithium electrophoresis, depending on the activity of the process and the type of drug therapy.

Application of Polymer Microspheres for Assessing the Role of Mechanical Factors in the Formation of Neutrophilic Extracellular Traps

2021 ◽  
Vol 16 (1) ◽  
pp. 96-102
Author(s):  
L. Yu. Basyreva ◽  
E. A. Fedorova ◽  
V. A. Polonskiy ◽  
I. V. Skopintsev ◽  
A. L. Luss ◽  
...  
Keyword(s):  
Polymer Microspheres ◽  
Extracellular Traps ◽  
Mechanical Factors

On Approaches to Taking into Account the Risks of Changing Climatic Conditions when Planning and Implementing Oil and Gas Projects

2021 ◽  
Vol 18 (1) ◽  
pp. 52-65
Author(s):  
P. N. Mikheev
Keyword(s):  
Climate Change ◽  
Oil And Gas ◽  
Oil And Gas Industry ◽  
Climatic Conditions ◽  
Qualitative Assessment ◽  
Physical Factors ◽  
Gas Industry ◽  
Climate Risks ◽  
The Impact

The article discusses issues related to the impact of climate change on the objects of the oil and gas industry. The main trends in climate change on a global and regional (on the territory of Russian Federation) scale are outlined. Possible approaches to the identification and assessment of climate risks are discussed. The role of climatic risks as physical factors at various stages of development and implementation of oil and gas projects is shown. Based on the example of oil and gas facilities in the Tomsk region, a qualitative assessment of the level of potential risk from a weather and climatic perspective is given. Approaches to creating a risk management and adaptation system to climate change are presented.

A Study of the Role of Heterogeneities in the Initial Stages of Corrosion of Glazes Using Dynamic Imaging Microellipsometry (DIM)

1996 ◽  
Vol 462 ◽  
Author(s):  
B.E. McCarthy ◽  
P.B. Vandiver ◽  
J. Kruger
Keyword(s):  
Residual Stress ◽  
Dynamic Imaging ◽  
Corrosion Process ◽  
Ceramic Production ◽  
Stress Fields ◽  
Process Dynamic ◽  
Glazed Ceramic ◽  
Mechanical Factors

ABSTRACTCommon processes used in glazed ceramic production often result in a glaze with a heterogeneous microstructure. Heterogeneities may be due to residual batch materials, intentionally added colorants and opacifiers and/or the products of devitrification and phase separation. To study the effect of heterogeneities in the corrosion process, dynamic imaging microellipsometry was used in-situ in aqueous solutions to measure spatially and temporally resolved changes in the surface of glasses (model glazes). The measurements showed increased durability near inclusions. Residual stress fields surrounding the heterogeneities influenced the results. Decoupling of chemical and mechanical factors causing this increased durability was not possible.

scholarly journals A bridge to progress further afield: The promise of a common framework on attentional capture

2021 ◽  
Author(s):  
Steven Most ◽  
Kim Curby
Keyword(s):  
Attentional Capture ◽  
Attentional Biases ◽  
Perceptual Expertise ◽  
Physical Factors ◽  
Attentional Allocation ◽  
Clinical Disorders ◽  
Common Framework ◽  
Emotional Resonance ◽  
Advance Theory

Although physical salience looms large in the attentional capture literature, stimuli can also capture attention via salience deriving from non-physical factors. Such psychological salience can stem, for example, from the emotional resonance of stimuli or their relevance to a person’s expertise. We consider how insights from a recently proposed framework for attentional capture can be used to advance theory and drive research on the role of emotion-driven attentional biases in clinical disorders and on how attentional allocation changes with the development of perceptual expertise. In return, we wonder how their common framework can be enriched through considerations of psychological salience.

Role of Aspirin Resistance, Mechanical Factors and Inflammation on Early Saphenous Vein Graft Thrombosis After CABG

2021 ◽  
Author(s):  
Dudy Arman hanafy ◽  
Budhi Setianto Setianto ◽  
Jusuf Rachmat ◽  
Soesanto ◽  
Arman Adel Abdullah ◽  
...  
Keyword(s):  
Saphenous Vein ◽  
Vein Graft ◽  
Graft Failure ◽  
Saphenous Vein Graft ◽  
Aspirin Resistance ◽  
Primary Role ◽  
Flow Measurements ◽  
Graft Thrombosis ◽  
Mechanical Factors

Abstract Objectives: This study was carried out to determine the role of pre-operative and transient aspirin resistance in the formation of early saphenous vein graft (SVG) thrombosis six weeks after coronary artery bypass graft (CABG) surgery and to analyze the other factors, such as mechanical and inflammation factors, that are also suspected of contributing to the formation of early thrombosis.Methods: Pre- and post-operative blood samples were taken from 99 subjects, whom 74 patients were undergoing elective on-pump CABG and receiving aspirin as monotherapy, for evaluation of inflammation parameters and the state of aspirin resistance using a Platelet Function Analyzer-200 (PFA-200). Transit time flow measurements (TTFM) were performed intra-operatively to determine mechanical factors. Multi-sliced computed tomography (MSCT) was done six weeks after surgery to determine the patency of the vein grafts.Result: In the 222 vein conduits, aspirin resistance was related to early vein graft failure due to thrombosis (p < 0.001; relative risk (RR) = 3.69). The massive increase of interleukin 6 (IL-6) levels after surgery were related to the existence of post-operative transient aspirin resistance (p < 0.001). Transient aspirin resistance (IL-6 > 122.5) was associated with early graft failure (p = 0.029; RR = 8.6) compared to the aspirin-sensitive group (IL-6 > 122.5).Conclusion: Aspirin resistance plays a primary role in early vein graft thrombosis. Transient aspirin resistance accompanied by an increase of inflammation factor (IL-6) significantly increases the risk of early vein graft thrombosis after CABG.

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