scholarly journals A bridge to progress further afield: The promise of a common framework on attentional capture

2021 ◽  
Author(s):  
Steven Most ◽  
Kim Curby
Keyword(s):  
Attentional Capture ◽  
Attentional Biases ◽  
Perceptual Expertise ◽  
Physical Factors ◽  
Attentional Allocation ◽  
Clinical Disorders ◽  
Common Framework ◽  
Emotional Resonance ◽  
Advance Theory

Although physical salience looms large in the attentional capture literature, stimuli can also capture attention via salience deriving from non-physical factors. Such psychological salience can stem, for example, from the emotional resonance of stimuli or their relevance to a person’s expertise. We consider how insights from a recently proposed framework for attentional capture can be used to advance theory and drive research on the role of emotion-driven attentional biases in clinical disorders and on how attentional allocation changes with the development of perceptual expertise. In return, we wonder how their common framework can be enriched through considerations of psychological salience.

TESTING GOAL-DRIVEN CAPTURE BY THREAT

2019 ◽  
Author(s):  
Chris Robert Harrison Brown
Keyword(s):  
Experimental Evidence ◽  
Attentional Capture ◽  
Critical Role ◽  
Experimental Manipulation ◽  
Contingent Capture ◽  
Top Down ◽  
Affective Stimuli ◽  
Clinical Disorders ◽  
Positive Stimuli

Attention has long been characterised within prominent models as reflecting a competition between goal-driven and stimulus-driven processes. It remains unclear, however, how involuntary attentional capture by affective stimuli, such as threat-laden content, fits into such models. While such effects were traditionally held to reflect stimulus-driven processes, recent research has increasingly implicated a critical role of goal-driven processes. Here we test an alternative goal-driven account of involuntary attentional capture by threat, using an experimental manipulation of goal-driven attention. To this end we combined the classic ‘contingent capture’ and ‘emotion-induced blink’ (EIB) paradigms in an RSVP task with both positive or threatening target search goals. Across six experiments, positive and threat distractors were presented in peripheral, parafoveal, and central locations. Across all distractor locations, we found that involuntary attentional capture by irrelevant threatening distractors could be induced via the adoption of a search goal for a threatening category; adopting a goal for a positive category conversely led to capture only by positive stimuli. Our findings provide direct experimental evidence for a causal role of voluntary goals in involuntary capture by irrelevant threat stimuli, and hence demonstrate the plausibility of a top-down account of this phenomenon. We discuss the implications of these findings in relation to current cognitive models of attention and clinical disorders.

scholarly journals The emerging role of mechanical and topographical factors in the development and treatment of nervous system disorders: dark and light sides of the force

2021 ◽  
Author(s):  
Natalia Bryniarska-Kubiak ◽  
Andrzej Kubiak ◽  
Małgorzata Lekka ◽  
Agnieszka Basta-Kaim
Keyword(s):  
Nervous System ◽  
Physical Factors ◽  
Nervous System Diseases ◽  
Therapeutic Approaches ◽  
System Disease ◽  
New Therapeutic Approaches ◽  
The Subject ◽  
Topographical Factors ◽  
New Treatment

AbstractNervous system diseases are the subject of intensive research due to their association with high mortality rates and their potential to cause irreversible disability. Most studies focus on targeting the biological factors related to disease pathogenesis, e.g. use of recombinant activator of plasminogen in the treatment of stroke. Nevertheless, multiple diseases such as Parkinson’s disease and Alzheimer’s disease still lack successful treatment. Recently, evidence has indicated that physical factors such as the mechanical properties of cells and tissue and topography play a crucial role in homeostasis as well as disease progression. This review aims to depict these factors’ roles in the progression of nervous system diseases and consequently discusses the possibility of new therapeutic approaches. The literature is reviewed to provide a deeper understanding of the roles played by physical factors in nervous system disease development to aid in the design of promising new treatment approaches. Graphic abstract

scholarly journals The Functional Role of Response Suppression during an Urge to Relieve Pain

2019 ◽  
Vol 31 (9) ◽  
pp. 1404-1421
Author(s):  
Kelsey K. Sundby ◽  
Johanna Wagner ◽  
Adam R. Aron
Keyword(s):  
Short Interval ◽  
Intracortical Inhibition ◽  
Gabaergic Interneuron ◽  
Response Suppression ◽  
Active Response ◽  
Relieve Pain ◽  
Clinical Disorders ◽  
Functional Relevance ◽  
Interneuron Activity

Being in the state of having both a strong impulse to act and a simultaneous need to withhold is commonly described as an “urge.” Although urges are part of everyday life and also important to several clinical disorders, the components of urge are poorly understood. It has been conjectured that withholding an action during urge involves active response suppression. We tested that idea by designing an urge paradigm that required participants to resist an impulse to press a button and gain relief from heat (one hand was poised to press while the other arm had heat stimulation). We first used paired-pulse TMS over motor cortex (M1) to measure corticospinal excitability of the hand that could press for relief, while participants withheld movement. We observed increased short-interval intracortical inhibition, an index of M1 GABAergic interneuron activity that was maintained across seconds and specific to the task-relevant finger. A second experiment replicated this. We next used EEG to better “image” putative cortical signatures of motor suppression and pain. We found increased sensorimotor beta contralateral to the task-relevant hand while participants withheld the movement during heat. We interpret this as further evidence of a motor suppressive process. Additionally, there was beta desynchronization contralateral to the arm with heat, which could reflect a pain signature. Strikingly, participants who “suppressed” more exhibited less of a putative “pain” response. We speculate that, during urge, a suppressive state may have functional relevance for both resisting a prohibited action and for mitigating discomfort.

The role of physical factors in the complex therapy of patients with rheumatoid arthritis

1985 ◽  
Vol 66 (4) ◽  
pp. 318-318
Author(s):  
L. V. Chernetsova ◽  
A. G. Ibragimova
Keyword(s):  
Rheumatoid Arthritis ◽  
Comparative Analysis ◽  
Drug Therapy ◽  
Electromagnetic Waves ◽  
Physical Factors ◽  
Complex Therapy ◽  
Decimeter Range

The comparative analysis of treatment of 76 patients with rheumatoid arthritis using electromagnetic waves of the decimeter range and lithium electrophoresis, depending on the activity of the process and the type of drug therapy.

On Approaches to Taking into Account the Risks of Changing Climatic Conditions when Planning and Implementing Oil and Gas Projects

2021 ◽  
Vol 18 (1) ◽  
pp. 52-65
Author(s):  
P. N. Mikheev
Keyword(s):  
Climate Change ◽  
Oil And Gas ◽  
Oil And Gas Industry ◽  
Climatic Conditions ◽  
Qualitative Assessment ◽  
Physical Factors ◽  
Gas Industry ◽  
Climate Risks ◽  
The Impact

The article discusses issues related to the impact of climate change on the objects of the oil and gas industry. The main trends in climate change on a global and regional (on the territory of Russian Federation) scale are outlined. Possible approaches to the identification and assessment of climate risks are discussed. The role of climatic risks as physical factors at various stages of development and implementation of oil and gas projects is shown. Based on the example of oil and gas facilities in the Tomsk region, a qualitative assessment of the level of potential risk from a weather and climatic perspective is given. Approaches to creating a risk management and adaptation system to climate change are presented.

scholarly journals A Research Pathway for Experimental Psychopathology: The Role of External Validity Criteria

2017 ◽  
Vol a4 (2) ◽  
pp. 129-140 ◽  
Author(s):  
Graham C L Davey
Keyword(s):  
External Validity ◽  
Healthy Individuals ◽  
Experimental Psychopathology ◽  
Clinical Disorders ◽  
Psychological Models ◽  
Validity Criteria ◽  
Psychological Knowledge ◽  
Healthy Participants

This paper outlines a putative pathway for experimental psychopathology research developing psychological models of clinical disorders. The pathway uses established external validity criteria to define the pathway and clarifies the important role that research conducted on healthy participants can play in our understanding of clinical disorders. Defining a research pathway for experimental psychopathology in this way has a number of benefits It would (1) make explicit the need to address the external validity of developed models, (2) provide a clear set of criteria that would be required to extend research on healthy individuals to diagnostic populations, and (3) recommend using general psychological knowledge when developing models of psychopathology.

scholarly journals Role of mechanical cues and hypoxia on the growth of tumor cells in strong and weak confinement: A dual in vitro–in silico approach

2020 ◽  
Vol 6 (13) ◽  
pp. eaaz7130 ◽  
Author(s):  
V. Le Maout ◽  
K. Alessandri ◽  
B. Gurchenkov ◽  
H. Bertin ◽  
P. Nassoy ◽  
...  
Keyword(s):  
In Silico ◽  
Time Course ◽  
Growth Dynamics ◽  
Tumor Model ◽  
Mechanistic Modeling ◽  
Physical Factors ◽  
Factors Affecting ◽  
Numerical Studies

Characterization of tumor growth dynamics is of major importance for cancer understanding. By contrast with phenomenological approaches, mechanistic modeling can facilitate disclosing underlying tumor mechanisms and lead to identification of physical factors affecting proliferation and invasive behavior. Current mathematical models are often formulated at the tissue or organ scale with the scope of a direct clinical usefulness. Consequently, these approaches remain empirical and do not allow gaining insight into the tumor properties at the scale of small cell aggregates. Here, experimental and numerical studies of the dynamics of tumor aggregates are performed to propose a physics-based mathematical model as a general framework to investigate tumor microenvironment. The quantitative data extracted from the cellular capsule technology microfluidic experiments allow a thorough quantitative comparison with in silico experiments. This dual approach demonstrates the relative impact of oxygen and external mechanical forces during the time course of tumor model progression.

scholarly journals Fresh perspectives on customer experience

2015 ◽  
Vol 29 (6/7) ◽  
pp. 430-435 ◽  
Author(s):  
Janet R. McColl-Kennedy ◽  
Anders Gustafsson ◽  
Elina Jaakkola ◽  
Phil Klaus ◽  
Zoe Jane Radnor ◽  
...  
Keyword(s):  
Research Agenda ◽  
Design Methodology ◽  
Customer Experience ◽  
Future Research ◽  
Dynamic Nature ◽  
Content Type ◽  
Research Questions ◽  
Advance Theory ◽  
Over Time

Purpose – The purpose of this paper is to provide directions for future research on: broadening the role of customers in customer experience; taking a practice-based approach to customer experience; and recognizing the holistic, dynamic nature of customer experience across all touch points and over time. Design/methodology/approach – The approach is conceptual identifying current gaps in research on customer experience. Findings – The findings include a set of research questions and research agenda for future research on customer experience. Originality/value – This research suggests fresh perspectives for understanding the customer experience which can inspire future research and advance theory and managerial practice.

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