Preparative separation and purification of flavonoids from Lamiophlomis rotata (Benth.) Kudo.

2017 ◽  
Vol 46 (6) ◽  
pp. 496-506 ◽  
Author(s):  
Yingyu Zhao ◽  
Zhenbin Chen ◽  
Jie Li ◽  
Zhen Liu ◽  
Donglei Liu ◽  
...  
Keyword(s):  
Diffusion Model ◽  
Adsorption Mechanism ◽  
Particle Diffusion ◽  
Optimal Conditions ◽  
Separation And Purification ◽  
Adsorption Dynamic ◽  
Plant Resources ◽  
Content Type ◽  
Intra Particle Diffusion ◽  
Macroporous Adsorption Resin

Purpose The purpose of the paper is to separate and purify flavonoids existed in Lamiophlomis rotata (Benth.) Kudo. by macroporous adsorption resin (MAR) mixed-bed technology. Design/methodology/approach The adsorption and desorption parameters were characterized by UV-VIS spectrophotometry. The optimal MAR mixed bed was screened based on the adsorption experiments; the experiment process was investigated by the order of single, two and three MAR mixed bed separately; and the adsorption performance, which was composed by the authority of 80 per cent adsorption ratios and 20 per cent desorption ratios, was adopted to screen MAR mixed bed for flavonoids. The adsorption dynamic investigated the order of reaction first, and then the adsorption mechanism was researched further. The adsorption thermodynamic investigated the adsorption isotherm first, and then the adsorption feature was analyzed. Findings This research found that MAR mixed bed of LS-840 + LSD301 with mass ratio of mLS840:mLSD301 = 3:2 was the optimized combination, and the optimal conditions of the adsorption were volume V = 50 mL, time t = 6.5 h, T = 40°C. The desorption conditions were ethanol content = 70 per cent, desorption time t = 3.0 h, T = 40°C. The adsorption dynamic experimental data fitted better to the pseudo-second-order, and the intra-particle-diffusion model was more suitable for expression of the adsorption mechanism in mesopores process, whereas the homogeneous particle-diffusion model was more suitable in microspores. The adsorption was a physical and multilayer adsorption, and the adsorption driving force was disappeared as it transferred to the fourth layer. Practical implications Find an efficient way to separate flavonoids that useful for human’s health, which can not only utilize of plant resources effectively, but also make outstanding contributions to medical industry. It has very high economic and social value. Originality/value This contribution provided a new way to separate flavonoids from Lamiophlomis rotata (Benth.) Kudo. Under the optimal conditions, the adsorption rate (F) of MAR mixed bed LS-840 + LSD301 to the flavonoids was 97.81 per cent, the desorption rate (D) was 90.02 per cent and the purity of flavonoids was dramatically increased about 2.08 fold of the crude extract from 28 to 58.4 per cent, and the recovery yield of flavonoids arrived at 91.6 per cent after a circle of adsorption/desorption operation.

A simple and efficient method for separation and purification of troxerutin on the SZ-3 resin

2020 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Yuhan Li ◽  
Xiaolin Mu ◽  
Haiting Kong ◽  
Hongchun Pan ◽  
Hong Liu
Keyword(s):  
High Purity ◽  
Sample Volume ◽  
Flavonoid Compound ◽  
Optimal Conditions ◽  
Separation And Purification ◽  
Environment Friendly ◽  
Content Type ◽  
The Status ◽  
Macroporous Adsorption Resin ◽  
First Time

Purpose In view of the current difficulty of separation of troxerutin, the purpose of the paper is to separate and purify semi-synthetic flavonoid compound troxerutin by macroporous adsorption resin (SZ-3). Design/methodology/approach Comparing the adsorption performance and resolution of three different polar resins and choosing a resin to optimize the process parameters such as sample volume, eluent concentration and elution temperature to obtain high-purity troxerutin. After separating and enriching by resin column chromatography, detected the sample by LC-MS analysis. Findings This research found that the optimal conditions of the adsorption and desorption were sample volume S = 90 mg/g resin, methanol concentration C = 25%, T = 20 °C. the content of troxerutin increased significantly from 88% to more than 96%. Then confirmed the sample was troxerutin by LC-MS. In addition, the resin could be used for at least 10 cycles in the separation and purification experiments of troxerutin. Originality/value Purification of troxerutin with new SZ-3 resin for the first time. Under the optimal conditions, the purity and recovery of troxerutin was 96.4% and 39%. In this study, the authors established a purification process of troxerutin successfully that was simple, economical, environment friendly, with high purity and high recovery rate to provide a reference program for changing the status of troxerutin separation difficulties.

COMPREHENSIVE UTILIZATION OF PHOSPHOGYPSUM: ADSORPTION OF METHYLENE BLUE AND ITS APPLICATION IN BRICKS

2021 ◽  
pp. 2150075
Author(s):  
YA GAO ◽  
DI SUN ◽  
CHENGLIANG HAN ◽  
JUNJUN HUANG
Keyword(s):  
Methylene Blue ◽  
Adsorption Mechanism ◽  
Raw Material ◽  
Particle Diffusion ◽  
Kinetic Behavior ◽  
Maximum Capacity ◽  
Comprehensive Utilization ◽  
Monolayer Adsorption ◽  
Intra Particle Diffusion ◽  
The One

In this work, comprehensive utilization of phosphogypsum was developed. Methylene blue (MB) in aqueous solution was adsorbed by waste phosphogypsum (PG), and then the MB-adsorbed PG was used to the fabrication of PG bricks. The adsorption mechanism and the strength of PG bricks also have been studied. The dye maximum capacity of PG monolayer adsorption was found to be 0.2[Formula: see text]mg/g. The kinetic behavior is more accordant with the intra-particle diffusion equation. The MB-adsorbed PG could be effectively used as a raw material for building material. The mechanical properties of PG bricks were little different from the one of the water-washed PG bricks. The 2h-flexural and compressing strengths were about 2.8[Formula: see text]MPa and 6[Formula: see text]MPa, the dry-flexural and compressing strengths were about 5[Formula: see text]MPa and 20[Formula: see text]MPa.

Application of the intra-particle diffusion model for activated carbon fibers in an aqueous medium

2012 ◽  
Vol 1373 ◽  
Author(s):  
Teresa Ramírez-Rodríguez ◽  
Fray de Landa Castillo-Alvarado
Keyword(s):  
Activated Carbon ◽  
Diffusion Model ◽  
Carbon Fibers ◽  
Aqueous Media ◽  
Particle Diffusion ◽  
Activated Carbon Fibers ◽  
Kinetics Of Adsorption ◽  
Intra Particle Diffusion ◽  
Pseudo Second Order ◽  
Kinetics Of

ABSTRACTThe intra-particle diffusion model (IPD), proposed by Weber and Morris has been applied to the analysis of the kinetics of adsorption on activated carbon fibers with phosphate groups in the removal of cadmium ions in aqueous media. It is evident that the removal of cadmium ion kinetic model of pseudo-second order provides a better fit than the model of pseudo-first order and the intra-particle diffusion model provides the best to the sample compared activating solution: grams fibers of 1:3.

Scandium adsorption from sulfuric-chloride solutions with activated carbons

2019 ◽  
pp. 49-55
Author(s):  
Wai Moe Aung ◽  
M. V. Marchenko ◽  
I. D. Troshkina
Keyword(s):  
Correlation Coefficient ◽  
Diffusion Model ◽  
Activated Carbons ◽  
Second Order ◽  
Model Description ◽  
Particle Diffusion ◽  
Diffusion Region ◽  
Chloride Solutions ◽  
Intra Particle Diffusion ◽  
Pseudo Second Order

The study covers scandium adsorption in batch conditions by VSK, DAS and PFT activated carbon grades (Russia) of different origin (сoconut shell, аnthracite, thermoset waste, respectively) from sulfuric acid-chloride solutions (pH = 2) simulating the composition of the underground leaching solutions of polymetallic ores. It was found that scandium adsorption by DAS and VSK carbons proceeds with the highest distribution coefficients (133 and 45.8 cm3/g, respectively). Isotherms of scandium adsorption with these carbons are linear and described by the Henry equation with constants 133 ± 21 and 46 ± 7 cm3/g, respectively. A limited solution volume method was used to obtain the integral kinetic curves of scandium adsorption. Their linearization according to the kinetic models of the pseudo-first, pseudo-second order, the Elovich model and the Weber–Morris intra-particle diffusion model indicates that the kinetics of scandium adsorption with VSK carbon having a higher correlation coefficient (0.999) is described using the pseudo-second order model. Description of the kinetic data obtained during the adsorption of scandium with DAS carbon showed that for all the models used the correlation coefficient is low (<0.939), while the highest value is observed when using the intra-particle diffusion model. It was suggested that the scandium adsorption process occurs in the mixed diffusion region. The possibility of scandium elution from VSK and DAS carbons with sodium carbonate solution (10 %) was studied in batch conditions, where the degree of scandium desorption in two stages of elution was 84.0 and 90.4 %, respectively.

Purification of flavonoids from glycyrrhiza by MAR mixed-bed

2018 ◽  
Vol 47 (5) ◽  
pp. 386-395
Author(s):  
XuDong Wang ◽  
Zhenbin Chen ◽  
Jiapeng Long ◽  
Chenglong Duan ◽  
Xueyan Du
Keyword(s):  
Design Methodology ◽  
Desorption Rate ◽  
Optimal Conditions ◽  
Mass Ratio ◽  
Liquid Ratio ◽  
Content Type ◽  
Visible Spectrophotometry ◽  
Adsorption Performance ◽  
Macroporous Adsorption Resin ◽  
Adsorption Resin

Purpose The purpose of this paper is to separate and purify flavonoids from glycyrrhiza by macroporous adsorption resin (MAR) mixed-bed technology. Design/methodology/approach The adsorption performance of MAR and MAR mixed bed for flavonoids was studied using ultraviolet-visible spectrophotometry. Findings The research shows that the MAR mixed bed of LZ-50+LZ-59 with a mass ratio of LZ-50:LZ-59(m:m) = 1:1 was the optimized combination with the optimal conditions of adsorption (pH = 6, T = 45°C) and desorption (liquid ratio R = 70%, T = 50°C, pH = 8) obtained, relatively. Originality/value This paper provides a novel way to separate flavonoids from glycyrrhiza. Under the optimal conditions, the adsorption rate (F) of MAR mixed-bed LZ-50+LZ-59 to the flavonoids was 62.5 per cent/g, the desorption rate (D) was 89.23 per cent and the purity was achieved at 80 per cent.

scholarly journals Effective adsorption of nitroaromatics at the low concentration by a newly synthesized hypercrosslinked resin

2017 ◽  
Vol 76 (9) ◽  
pp. 2328-2336 ◽  
Author(s):  
Chuanhong Wang ◽  
Chao Xu ◽  
Weizhi Sun ◽  
Fusheng Liu ◽  
Shitao Yu ◽  
...  
Keyword(s):  
Adsorption Capacity ◽  
Diffusion Model ◽  
Fixed Bed ◽  
Mesoporous Structure ◽  
Bet Surface Area ◽  
Particle Diffusion ◽  
Adsorption Thermodynamics ◽  
Film Diffusion ◽  
Low Concentrations ◽  
Intra Particle Diffusion

Abstract In the present study, a series of hypercrosslinked resins (CH series) was prepared in systematically designed conditions for the adsorption of nitroaromatics from aqueous solution. The newly synthesized CH-10 possesses a Brunauer–Emmett–Teller (BET) surface area up to 1,329.3 m2/g which is larger than that of the widely used hypercrosslinked resin H-103 and it exhibits great advantage over H-103 when subjected to nitrobenzene at low concentrations. The adsorption capacity of CH-10 for nitrobenzene is 1.4 times as much as that of H-103 at the concentration of 100 mg/L. Kinetic study by film diffusion model and intra-particle diffusion model revealed that its distinctive mesoporous structure within pore diameters between 2 and 6 nm played significant role in the mass transfer at low concentrations, and these unique mesopores also resulted in better adsorption capacity, which was confirmed by adsorption thermodynamics study. Moreover, the CH series displayed a good affinity to a wide scope of nitroaromatics and exhibited excellent dynamic adsorption and desorption properties in fixed bed.

Separation of flavonoids in the leaves of Sophora japonica by macroporous adsorption resin mixed-bed technology

2017 ◽  
Vol 46 (3) ◽  
pp. 235-243 ◽  
Author(s):  
Yingyu Zhao ◽  
Zhenbin Chen ◽  
Donglei Liu ◽  
Jiapeng Long ◽  
Duolong Di
Keyword(s):  
Experimental Result ◽  
Optimal Conditions ◽  
Sophora Japonica ◽  
Adsorption Volume ◽  
Content Type ◽  
Macroporous Adsorption Resin ◽  
Novel Method ◽  
Adsorption Resin ◽  
Adsorption Desorption ◽  
Practical Implications

Purpose The purpose of this paper is to separate and purify flavonoids existing in the leaves of Sophora japonica by a novel method, macroporous adsorption resin (MAR) mixed-bed technology, and the optimal MAR mixed bed was screened based on the adsorption experimental result with the order of single, two, three and four MAR mixed bed separately. Design/methodology/approach The adsorption performance of MAR and MAR mixed bed for flavonoids was studied using ultraviolet – visible (UV-VIS) spectrophotometry. Findings This research showed that the MAR mixed bed of LZ-54 + LZ-67 with a mass ratio of mLZ-54:mLZ-67 = 1:1 was the optimized combination with the optimal conditions of adsorption (volume V = 140 mL, pH = 5, T = 35°C) and desorption (liquid ratio R = 50 per cent, T = 30°C, pH = 6) obtained, relatively. Practical implications This study aims to find an efficient way of separating flavonoids and other components that are useful for human health from Sophora japonica, which is complying with the policy of sustainable development. Originality/value This contribution provided a novel way to separate flavonoids from Sophora japonica. Under the optimal conditions, the adsorption rate (F) of MAR mixed bed LZ-54 + LZ-67 to the flavonoids was 63.65 per cent, the desorption rate (D) was 87.31 per cent and the purity was dramatically achieved at 58.17 per cent from 17.67 per cent after a round of adsorption/desorption operation.

Separation and purification of flavonoids from polygonum cuspidatum using macroporous adsorption resin

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Xiaoyan Zhang ◽  
Runtian Wang ◽  
Yingyu Zhao ◽  
Jun Zhang ◽  
Boyuan Zhang ◽  
...  
Keyword(s):  
Theoretical Research ◽  
Flavonoid Compound ◽  
Utilization Rate ◽  
Separation Performance ◽  
Polygonum Cuspidatum ◽  
Separation And Purification ◽  
Content Type ◽  
Medicinal Value ◽  
Initial Extract ◽  
Macroporous Adsorption Resin

Purpose This paper aims to evaluate the separation and purification characteristics of flavonoids from polygonum cuspidatum (PC) extracts by using macroporous adsorption resins (MAR) mixed bed to improve the utilization rate of flavonoids. Design/methodology/approach Taking the separation performance of flavonoids as an evaluation index, the best MAR were screened from 31 sorts of MAR and combined the best MAR to form a MAR mixed bed for adsorption and separation of flavonoids. Findings By studying the separation conditions that affect flavonoids, the results showed that resin LZ-72 has best separation and purification effect on flavonoids under the optimal adsorption and desorption conditions, the purity of the obtained flavonoid compound reaches 82.50%, 2.66 times of the initial extract, and the recovery rate reaches 89.70%. Theoretical research results have shown that the adsorption of flavonoids by MAR conforms to the pseudo-second-order kinetics and Freundlich models. Practical implications Because the flavonoids in PC have great medicinal value, the purpose of this work is to develop a method of separating and purifying flavonoids from PC, which will provide a certain foundation for the development of medicine. Originality/value This contribution provided a novel way to separate flavonoids from PC. Under the optimal conditions, the content of flavonoids in the product was increased 2.66-fold from 31.01% to 82.50%, and the recovery yield was 89.70%.

Preparation of LX1180-SO3− and the comparative study on the adsorption behaviour of LX1180 and LX1180-SO3−

2016 ◽  
Vol 45 (1) ◽  
pp. 1-9 ◽  
Author(s):  
Ting Huo ◽  
Zhenbin Chen ◽  
Jiapeng Long ◽  
Lei Kang ◽  
Duolong Di ◽  
...  
Keyword(s):  
Adsorption Capacity ◽  
Adsorption Kinetics ◽  
Adsorption Behaviour ◽  
Separation And Purification ◽  
Healthcare Applications ◽  
Adsorption And Desorption ◽  
Content Type ◽  
Isolation And Purification ◽  
Macroporous Adsorption Resin ◽  
Matching Degree

Purpose – This work focused on the sulphonation modification research of highly crosslinking non-polarity macroporous adsorption resin (MAR) LX1180; the adsorption behaviour of LX1180 and its chloromethylation- and sulphonation-modified products (LX1180-Cl and LX1180-SO3−); and the influence of the structure parameters matching degree of MAR and flavonoids on the adsorption feature and adsorption kinetics. Design/methodology/approach – LX1180-SO3− was obtained by the processes of chloromethylation first and then sulphonation. LX1180-Cl and LX1180-SO3− were prepared through the principle of substitution reaction from LX1180 and LX1180-Cl, respectively. First, Monochloromethyl ether (ME), pre-treated ZnCl2, NaCl and iron powder were added into the swollen LX1180 to obtain the chloromethylated LX1180. Thereafter, NaCl, NaOH and SAA were added into the swollen LX1180-Cl to obtain the sulphonation modification LX1180. The conditions were investigated and optimised; the structures of LX1180-Cl and LX1180-SO3− were characterised by Fourier transform infrared chromatography (FTIR) and a specific surface area instrument. Finally, the adsorption kinetics and adsorption isotherm were used to evaluate the adsorption capacity of LX1180-Cl and LX1180-SO3− for flavonoids, and the adsorptions and desorptions of LX1180-SO3− with different sulphonation degree on different flavonoids were investigated systemically. Findings – Results showed that LX1180-Cl and LX1180-SO3− had been prepared successfully, and that after the sulphonation, the adsorption capacity tended to increase with the increase of adsorption time, and the equilibrium adsorption capacity of LX1180-SO3− was also higher than that of LX1180. Research limitations/implications – The research only investigated the adsorption and desorption properties for only one kind of functional group, and other functional groups should also be studied in future work. Practical implications – This contribution can provide a further base for the research of separation and purification of natural products with the aim to improve food additive removal or isolation and purification of flavonoids used for healthcare applications. Originality/value – The adsorptions and desorptions of LX1180-SO3− with different sulphonation degree on different flavonoids were investigated. The relationship between sulphonation degree and the adsorption and desorption capacities of flavonoids were also explored, and the results showed that with the increase of sulphonation degree, the adsorption of LX1180-SO3− to rutin and cyanidin was maximum, while the desorption ratio was minimum at the same sulphonation degree; this phenomenon could be ascribed to the variation in the polarity matching degree.

Adsorption of p-Cresol by Mesoporous Activated Carbon. II. Mechanism studies and data modeling

2017 ◽  
Vol 68 (3) ◽  
pp. 496-499
Author(s):  
Mihaela Neagu ◽  
Daniela Roxana Popovici ◽  
Loredana Elena Vijan ◽  
Catalina Calin
Keyword(s):  
Activated Carbon ◽  
Adsorption Mechanism ◽  
Adsorption Process ◽  
Point Of Zero Charge ◽  
Particle Diffusion ◽  
Ftir Analysis ◽  
Film Diffusion ◽  
Mesoporous Activated Carbon ◽  
Boehm Titration ◽  
Intra Particle Diffusion

In this work, the adsorption mechanism of p-cresol from aqueous solution onto mesoporous activated carbon was investigated. The mechanism of the adsorption process was determined from Weber-Morris and Boyd models. By graphical and statistical analysis was demonstrated that both film-diffusion and intra-particle diffusion are concurrent in adsorption mechanism. The adsorption mechanism of p-cresol onto mesoporous activated carbon was sustained by FTIR analysis, Boehm titration and the point of zero charge of the GAC.

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