Separation and purification of flavonoids from polygonum cuspidatum using macroporous adsorption resin

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Xiaoyan Zhang ◽  
Runtian Wang ◽  
Yingyu Zhao ◽  
Jun Zhang ◽  
Boyuan Zhang ◽  
...  
Keyword(s):  
Theoretical Research ◽  
Flavonoid Compound ◽  
Utilization Rate ◽  
Separation Performance ◽  
Polygonum Cuspidatum ◽  
Separation And Purification ◽  
Content Type ◽  
Medicinal Value ◽  
Initial Extract ◽  
Macroporous Adsorption Resin

Purpose This paper aims to evaluate the separation and purification characteristics of flavonoids from polygonum cuspidatum (PC) extracts by using macroporous adsorption resins (MAR) mixed bed to improve the utilization rate of flavonoids. Design/methodology/approach Taking the separation performance of flavonoids as an evaluation index, the best MAR were screened from 31 sorts of MAR and combined the best MAR to form a MAR mixed bed for adsorption and separation of flavonoids. Findings By studying the separation conditions that affect flavonoids, the results showed that resin LZ-72 has best separation and purification effect on flavonoids under the optimal adsorption and desorption conditions, the purity of the obtained flavonoid compound reaches 82.50%, 2.66 times of the initial extract, and the recovery rate reaches 89.70%. Theoretical research results have shown that the adsorption of flavonoids by MAR conforms to the pseudo-second-order kinetics and Freundlich models. Practical implications Because the flavonoids in PC have great medicinal value, the purpose of this work is to develop a method of separating and purifying flavonoids from PC, which will provide a certain foundation for the development of medicine. Originality/value This contribution provided a novel way to separate flavonoids from PC. Under the optimal conditions, the content of flavonoids in the product was increased 2.66-fold from 31.01% to 82.50%, and the recovery yield was 89.70%.

A simple and efficient method for separation and purification of troxerutin on the SZ-3 resin

2020 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Yuhan Li ◽  
Xiaolin Mu ◽  
Haiting Kong ◽  
Hongchun Pan ◽  
Hong Liu
Keyword(s):  
High Purity ◽  
Sample Volume ◽  
Flavonoid Compound ◽  
Optimal Conditions ◽  
Separation And Purification ◽  
Environment Friendly ◽  
Content Type ◽  
The Status ◽  
Macroporous Adsorption Resin ◽  
First Time

Purpose In view of the current difficulty of separation of troxerutin, the purpose of the paper is to separate and purify semi-synthetic flavonoid compound troxerutin by macroporous adsorption resin (SZ-3). Design/methodology/approach Comparing the adsorption performance and resolution of three different polar resins and choosing a resin to optimize the process parameters such as sample volume, eluent concentration and elution temperature to obtain high-purity troxerutin. After separating and enriching by resin column chromatography, detected the sample by LC-MS analysis. Findings This research found that the optimal conditions of the adsorption and desorption were sample volume S = 90 mg/g resin, methanol concentration C = 25%, T = 20 °C. the content of troxerutin increased significantly from 88% to more than 96%. Then confirmed the sample was troxerutin by LC-MS. In addition, the resin could be used for at least 10 cycles in the separation and purification experiments of troxerutin. Originality/value Purification of troxerutin with new SZ-3 resin for the first time. Under the optimal conditions, the purity and recovery of troxerutin was 96.4% and 39%. In this study, the authors established a purification process of troxerutin successfully that was simple, economical, environment friendly, with high purity and high recovery rate to provide a reference program for changing the status of troxerutin separation difficulties.

The optimization design of uniform’s hanging production line

2015 ◽  
Vol 27 (3) ◽  
pp. 370-389 ◽  
Author(s):  
Huirong Cui ◽  
Yinong Yan
Keyword(s):  
Production Process ◽  
Production Line ◽  
Production Efficiency ◽  
Assembly Line ◽  
Group Technology ◽  
Lean Production ◽  
Optimization Methods ◽  
Theoretical Research ◽  
Utilization Rate ◽  
Content Type

Purpose – Garment manufacturing is a traditional industry with global competition. The most critical part is streamline, as it generally involves a great number of operations. The purpose of this paper is to, based on the model of group technology (GT), sum up the methods of assembly line optimization to optimize the streamline, so that the machines of the workstation can perform the assigned tasks with a balanced loading. Design/methodology/approach – In this paper, the methods of obtaining and optimizing data includes literature, research and optimization methods of basing on GT model. The main direction of literature has two aspects: Lean production theory and streamline assignment. Research mainly concludes three aspects: research place, research object and the research content. The method of time determination is averaging the testing values of repeated measurements. Optimization methods of basing on GT model mainly include combination of the same type of technologic processes in sequence, combination of independent branch process, the combination of mainstream and branch processes and offside combination of the same type of processes. Findings – After optimization, in the utilization rate of equipment: hanging system ratio was increased from 22.95 to 62.12 percent, which greatly improved the utilization rate of enterprise equipment. In equipment layout: hanging equipment layout was turned linear type into “U” type, which realized the synchronization of production. GT model will be well applied in the garment production streamline. Compared with other enterprises, A company has large garment hanging system, which reflects the advanced, comprehensive, representative. Therefore, the paper applied optimization methods to trousers, production efficiency has been improved greatly, the utilization rate of equipment is promoted and reworking phenomenon is reduced greatly. Research limitations/implications – Through the optimization of the production process and equipment layout, the A company’s compiling efficiency has been greatly improved, but how can the system become computerized, accurately and intelligence, which has been an important direction of research now. Practical implications – By optimizing, it is fully proved that applying GT to the streamline optimization is feasible. GT is an important branch of Lean production, summing up the optimization methods basing on the GT model to optimize the streamline not only enriches the relevant theory research, but also provides a theoretical basis for the practical production. GT model not only can be used in the shirt production process, as for other production processes, for example, trousers, skirts can also be widely applied, which realizes the theory application in the practical production. Originality/value – The originality of this paper is that through the analysis of the model of GT, the paper sums up the methods of assembly line optimization to optimize the streamline. Although the model of GT is used widely in electronics, automobile and industry, it is relatively weak in the optimization of garment production line, there are not many literatures on practical application of group technology in the clothing. Besides, the paper is applied to practical production, which not only can improve production efficiency, but also make the theoretical research have basis and combine the theory and practical production.

Preparation of LX1180-SO3− and the comparative study on the adsorption behaviour of LX1180 and LX1180-SO3−

2016 ◽  
Vol 45 (1) ◽  
pp. 1-9 ◽  
Author(s):  
Ting Huo ◽  
Zhenbin Chen ◽  
Jiapeng Long ◽  
Lei Kang ◽  
Duolong Di ◽  
...  
Keyword(s):  
Adsorption Capacity ◽  
Adsorption Kinetics ◽  
Adsorption Behaviour ◽  
Separation And Purification ◽  
Healthcare Applications ◽  
Adsorption And Desorption ◽  
Content Type ◽  
Isolation And Purification ◽  
Macroporous Adsorption Resin ◽  
Matching Degree

Purpose – This work focused on the sulphonation modification research of highly crosslinking non-polarity macroporous adsorption resin (MAR) LX1180; the adsorption behaviour of LX1180 and its chloromethylation- and sulphonation-modified products (LX1180-Cl and LX1180-SO3−); and the influence of the structure parameters matching degree of MAR and flavonoids on the adsorption feature and adsorption kinetics. Design/methodology/approach – LX1180-SO3− was obtained by the processes of chloromethylation first and then sulphonation. LX1180-Cl and LX1180-SO3− were prepared through the principle of substitution reaction from LX1180 and LX1180-Cl, respectively. First, Monochloromethyl ether (ME), pre-treated ZnCl2, NaCl and iron powder were added into the swollen LX1180 to obtain the chloromethylated LX1180. Thereafter, NaCl, NaOH and SAA were added into the swollen LX1180-Cl to obtain the sulphonation modification LX1180. The conditions were investigated and optimised; the structures of LX1180-Cl and LX1180-SO3− were characterised by Fourier transform infrared chromatography (FTIR) and a specific surface area instrument. Finally, the adsorption kinetics and adsorption isotherm were used to evaluate the adsorption capacity of LX1180-Cl and LX1180-SO3− for flavonoids, and the adsorptions and desorptions of LX1180-SO3− with different sulphonation degree on different flavonoids were investigated systemically. Findings – Results showed that LX1180-Cl and LX1180-SO3− had been prepared successfully, and that after the sulphonation, the adsorption capacity tended to increase with the increase of adsorption time, and the equilibrium adsorption capacity of LX1180-SO3− was also higher than that of LX1180. Research limitations/implications – The research only investigated the adsorption and desorption properties for only one kind of functional group, and other functional groups should also be studied in future work. Practical implications – This contribution can provide a further base for the research of separation and purification of natural products with the aim to improve food additive removal or isolation and purification of flavonoids used for healthcare applications. Originality/value – The adsorptions and desorptions of LX1180-SO3− with different sulphonation degree on different flavonoids were investigated. The relationship between sulphonation degree and the adsorption and desorption capacities of flavonoids were also explored, and the results showed that with the increase of sulphonation degree, the adsorption of LX1180-SO3− to rutin and cyanidin was maximum, while the desorption ratio was minimum at the same sulphonation degree; this phenomenon could be ascribed to the variation in the polarity matching degree.

Preparative separation and purification of flavonoids from Lamiophlomis rotata (Benth.) Kudo.

2017 ◽  
Vol 46 (6) ◽  
pp. 496-506 ◽  
Author(s):  
Yingyu Zhao ◽  
Zhenbin Chen ◽  
Jie Li ◽  
Zhen Liu ◽  
Donglei Liu ◽  
...  
Keyword(s):  
Diffusion Model ◽  
Adsorption Mechanism ◽  
Particle Diffusion ◽  
Optimal Conditions ◽  
Separation And Purification ◽  
Adsorption Dynamic ◽  
Plant Resources ◽  
Content Type ◽  
Intra Particle Diffusion ◽  
Macroporous Adsorption Resin

Purpose The purpose of the paper is to separate and purify flavonoids existed in Lamiophlomis rotata (Benth.) Kudo. by macroporous adsorption resin (MAR) mixed-bed technology. Design/methodology/approach The adsorption and desorption parameters were characterized by UV-VIS spectrophotometry. The optimal MAR mixed bed was screened based on the adsorption experiments; the experiment process was investigated by the order of single, two and three MAR mixed bed separately; and the adsorption performance, which was composed by the authority of 80 per cent adsorption ratios and 20 per cent desorption ratios, was adopted to screen MAR mixed bed for flavonoids. The adsorption dynamic investigated the order of reaction first, and then the adsorption mechanism was researched further. The adsorption thermodynamic investigated the adsorption isotherm first, and then the adsorption feature was analyzed. Findings This research found that MAR mixed bed of LS-840 + LSD301 with mass ratio of mLS840:mLSD301 = 3:2 was the optimized combination, and the optimal conditions of the adsorption were volume V = 50 mL, time t = 6.5 h, T = 40°C. The desorption conditions were ethanol content = 70 per cent, desorption time t = 3.0 h, T = 40°C. The adsorption dynamic experimental data fitted better to the pseudo-second-order, and the intra-particle-diffusion model was more suitable for expression of the adsorption mechanism in mesopores process, whereas the homogeneous particle-diffusion model was more suitable in microspores. The adsorption was a physical and multilayer adsorption, and the adsorption driving force was disappeared as it transferred to the fourth layer. Practical implications Find an efficient way to separate flavonoids that useful for human’s health, which can not only utilize of plant resources effectively, but also make outstanding contributions to medical industry. It has very high economic and social value. Originality/value This contribution provided a new way to separate flavonoids from Lamiophlomis rotata (Benth.) Kudo. Under the optimal conditions, the adsorption rate (F) of MAR mixed bed LS-840 + LSD301 to the flavonoids was 97.81 per cent, the desorption rate (D) was 90.02 per cent and the purity of flavonoids was dramatically increased about 2.08 fold of the crude extract from 28 to 58.4 per cent, and the recovery yield of flavonoids arrived at 91.6 per cent after a circle of adsorption/desorption operation.

scholarly journals Hydrogen Separation and Purification from Various Gas Mixtures by Means of Electrochemical Membrane Technology in the Temperature Range 100–160 °C

Membranes ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 282
Author(s):  
Leandri Vermaak ◽  
Hein W. J. P. Neomagus ◽  
Dmitri G. Bessarabov
Keyword(s):  
Hydrogen Permeability ◽  
Gas Mixtures ◽  
Open Circuit ◽  
Hydrogen Separation ◽  
Proton Exchange ◽  
Limiting Current ◽  
Separation Performance ◽  
Separation And Purification ◽  
Irreversible Damage ◽  
Temperature Range

This paper reports on an experimental evaluation of the hydrogen separation performance in a proton exchange membrane system with Pt-Co/C as the anode electrocatalyst. The recovery of hydrogen from H2/CO2, H2/CH4, and H2/NH3 gas mixtures were determined in the temperature range of 100–160 °C. The effects of both the impurity concentration and cell temperature on the separation performance of the cell and membrane were further examined. The electrochemical properties and performance of the cell were determined by means of polarization curves, limiting current density, open-circuit voltage, hydrogen permeability, hydrogen selectivity, hydrogen purity, and cell efficiencies (current, voltage, and power efficiencies) as performance parameters. High purity hydrogen (>99.9%) was obtained from a low purity feed (20% H2) after hydrogen was separated from H2/CH4 mixtures. Hydrogen purities of 98–99.5% and 96–99.5% were achieved for 10% and 50% CO2 in the feed, respectively. Moreover, the use of proton exchange membranes for electrochemical hydrogen separation was unsuccessful in separating hydrogen-rich streams containing NH3; the membrane underwent irreversible damage.

3 D printing technology and experimental study of chitosan gel using atomized solidification liquid-assisted extrusion molding

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Yangwei Wang ◽  
Peilun Lv ◽  
Jian Li ◽  
Liying Yu ◽  
Guodong Yuan ◽  
...  
Keyword(s):  
3D Printing ◽  
Three Dimensional ◽  
Theoretical Research ◽  
Error Sources ◽  
Printing Technology ◽  
Content Type ◽  
Printing Ink ◽  
Printing Parameters ◽  
Chitosan Gel ◽  
Printing Method

Purpose This paper aims to propose a suitable atomizing solidification chitosan (CS) gel liquid extrusion molding technology for the three dimensional (3D) printing method, and experiments verify the feasibility of this method. Design/methodology/approach This paper mainly uses experimental means, combined with theoretical research. The preparation method, solidification forming method and 3D printing method of CS gel solution were studied. The CS gel printing mechanism and printing error sources are analyzed on the basis of the CS gel ink printing results, printing performance with different ratios of components by constructing a gel print prototype, experiments evaluating the CS gel printing technology and the effects of the process parameters on the scaffold formation. Findings CS printing ink was prepared; the optimal formula was found; the 3 D printing experiment of CS was completed; the optimal printing parameters were obtained; and the reliability of the forming prototype, printing ink and gel printing process was verified, which allowed for the possibility to apply the 3 D printing technology to the manufacturing of a CS gel structure. Originality/value This study can provide theoretical and technical support for the potential application of CS 3 D printed gels in tissue engineering.

A study on next‐generation digital library using context‐awareness technology

2013 ◽  
Vol 31 (2) ◽  
pp. 236-253 ◽  
Author(s):  
Younghee Noh
Keyword(s):  
Digital Library ◽  
Digital Libraries ◽  
Context Awareness ◽  
Theoretical Research ◽  
Context Aware ◽  
Semantic Retrieval ◽  
Next Generation ◽  
Climate Control ◽  
Content Type ◽  
Reference Services

PurposeThis study seeks to examine the concepts of context, context‐awareness, and context‐awareness technology needed for applying context‐awareness technology to the next‐generation of digital libraries, and proposed context‐aware services that can be applied to any situation by illustrating some library contexts.Design/methodology/approachThe paper investigated both theoretical research and case analysis studies before suggesting a service model for context‐awareness‐based libraries by examining the context, context‐awareness, and context‐awareness technology in depth.FindingsThis paper derived possible library services which could be provided if context‐awareness services are implemented by examining and analyzing case studies and systems constructed in other fields. A library‐applied context‐aware system could recognize users entering the library and provide optimal services tailored to each situation for both new and existing users. In addition, the context‐awareness‐based library could provide context‐awareness‐based reference services, context‐awareness‐based loan services, and cater to other user needs in the stacks, research space, and a variety of other information spaces. The context‐awareness‐based library could also recognize users in need of emergency assistance by detecting the user's behavior, movement path, and temperature, etc. Comfort or climate‐control services could provide the user with control of the temperature, humidity, illumination and other environmental elements to fit the circumstances of users, books, and instruments through context‐aware technology.Practical implicationsNext‐generation digital libraries apply new concepts such as semantic retrieval, real‐time web, cloud computing, mobile web, linked data, and context‐awareness. Context‐awareness‐based libraries can provide applied context‐awareness access service, reactive space according to the user's access, applied context‐awareness lobbies, applied context‐awareness reference services, and applied context‐awareness safety services, context‐awareness‐based comfort services and so on.Originality/valueReal instances of libraries applying context‐aware technology are few, according to the investigative results of this study. The study finds that the next‐generation digital library using context‐awareness technology can provide the best possible service for the convenience of its users.

scholarly journals Archives, libraries and museums in the Nordic model of the public sphere

2018 ◽  
Vol 74 (1) ◽  
pp. 187-194 ◽  
Author(s):  
Håkon Larsen
Keyword(s):  
Public Sphere ◽  
Information Science ◽  
Theoretical Research ◽  
Library And Information Science ◽  
Archival Science ◽  
Content Type ◽  
Public Spheres ◽  
The Public ◽  
The Public Sphere

Purpose The purpose of this paper is to discuss the role of ALM organizations within a Nordic model of the public sphere. Design/methodology/approach This is a conceptual paper discussing the role of archives, libraries and museums in light of a societal model of the Nordic public sphere. Throughout the discussions, the author draw on empirical and theoretical research from sociology, political science, media studies, cultural policy studies, archival science, museology, and library and information science to help advance our understanding of these organizations in a wider societal context. Findings The paper shows that ALM organizations play an important role for the infrastructure of a civil public sphere. Seen as a cluster, these organizations are providers of information that can be employed in deliberative activities in mediated public spheres, as well as training arenas for citizens to use prior to entering such spheres. Furthermore, ALM organizations are themselves public spheres, as they can serve specific communities and help create and maintain identities, and solidarities, all of which are important parts of a civil public sphere. Research limitations/implications Future research should investigate whether these roles are an important part of ALM organizations contribution to public spheres in other regions of the world. Originality/value Through introducing a theoretical model developed within sociology and connecting it to ongoing research in archival science, museology, and library and information science, the author connects the societal role of archives, libraries, and museums to broader discussions within the social sciences.

Searching for new saving behavior theories

2014 ◽  
Vol 32 (4) ◽  
pp. 279-299 ◽  
Author(s):  
Kent Eriksson ◽  
Cecilia Hermansson
Keyword(s):  
Social Exchange ◽  
Financial Services ◽  
Model Development ◽  
Customer Relationships ◽  
Customer Relationship ◽  
Theoretical Research ◽  
Marketing Theory ◽  
Savings Behavior ◽  
Content Type ◽  
Saving Behavior

Purpose – The purpose of this paper is to develop a model of bank advisor/customer relationships and customer saving behavior. Design/methodology/approach – The research is a theoretical review and model development of savings behavior and bank advisor/customer relationships. The review is used for the development of a model of bank advisor/customer relationships, and their effect on savings behavior. Findings – Findings are a model that distinguishes three kinds of exchange (relational, interimistic, and transaction) in between bank advisor and customer. The three kinds of exchange then influence customer savings behavior. Research limitations/implications – The implications of this research is that it points to that relationship marketing theory can be used in the analysis of how bank advisors influence customer savings behavior. Practical implications – For regulators and financial services firms, these findings point to how the role of bank advisors for consumer savings behavior can be analyzed. This is important, as much policy work presumes that advisors influence customer savings behavior, but the knowledge base for that presumption needs to be better understood. Social implications – The paper contributes toward a better understanding of the social exchange between bank employees and customers as regards savings products. Originality/value – This paper is original because it includes many theoretical research fields, and because it connects the bank advisor and customer relationship with the customer's savings behavior.

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