We examined the relationship of tolerance of ambiguity to severe global factors and specific types of anomalous or paranormal experience. 107 undergraduate students completed MacDonald's 1970 AT-20 and the Anomalous Experiences Inventory of Kumar, Pekala, and Gallagher. Scores on the five subscales of the Anomalous Experiences Inventory correlated differently with tolerance of ambiguity. Global paranormal beliefs, abilities, experiences, and drug use were positively associated with tolerance of ambiguity, whereas a fear of paranormal experience showed a negative relation. The specific types of anomalous experiences that correlated with tolerance of ambiguity often involved internal or physiological experience, e.g., precognitive dreams, memories of reincarnation, visual apparitions, and vestibular alterations. We generally found no effects of age or sex. These results are consistent with the idea that some paranormal experiences are misattributions of internal experience to external (‘paranormal’) sources, a process analogous to mechanisms underpinning delusions and hallucinations.