Is Damp Heat Degradation of c-Si Modules Essentially Universal?

2019 ◽  
Author(s):  
Reza Asadpour ◽  
Muhammad A. Alam
Keyword(s):  
Heat Degradation

scholarly journals DEVELOPMENT OF HPLC STABILITY DEMONSTRATING METHODOLOGY FOR QUANTIFYING AZELNIDIPINE AND TELMISARTAN IN TABLETS AND BULK TYPES: VALIDATION FOLLOWING ICH DIRECTIVES

2021 ◽  
pp. 298-305
Author(s):  
KRISHNAPHANISRI PONNEKANTI ◽  
K. SUNITHA
Keyword(s):  
Acid Base ◽  
Testing Conditions ◽  
Heat Degradation ◽  
Photodiode Array ◽  
Recovery Percentage ◽  
Inner Diameter ◽  
The Stability ◽  
First Time ◽  
Oxidation Degradation ◽  
Degradation Testing

Objective: Azelnidipine (AZEL) and Telmisartan (TELM) combination is referred to the sufferers of hypertension. No analytical process has yet been mentioned for the TELM and AZEL combination analysis. We, therefore, have designed for its first time stability demonstrating methodology based on HPLC for analysing TELM and AZEL in the tablets and bulk. Methods: The assay of TELM and AZEL was get done on a 250 mm length C18 column (Supelco, 4.6 mm inner diameter, 5.0 μm particle size), and utilized 0.1M Na2SO4 (pH 3.6) and acetonitrile (55% volume:  45% volume) as the mobile solvents phase, at a stream rate 1.0 ml/min. HPLC recognition of TELM and AZEL was taken by a photodiode array sensor set at 258 nm. For validation of the stability demonstrating methodology proposed in terms of sensitivity, precision, specificity, linearity, device adequacy, robustness and accuracy, ICH directives were followed. Results: Calibration curves of TELM and AZEL were generated in the array of 20-60 µg/ml and 4-12 µg/ml with recovery percentage ranges of 99.62%-101.05% and 97.76%-100.17%, and detection limits of 0.020 µg/ml and 0.009 µg/ml, respectively. TELM and AZEL stability was inspected in the existence of acid, base, light, heat, and oxidation and it was realised to be more stable under oxidation degradation testing conditions employed when compared to acid, alkaline, photo, and heat degradation testing conditions applied. Conclusion: The observations demonstrated that the described HPLC stability demonstrating methodology was suitable for quantitating TELM and AZEL combination in tablets and bulk.

scholarly journals Heat Degradation of Low Density Poly(ethylene) in Material Recycle

2006 ◽  
Vol 53 (2) ◽  
pp. 63-69
Author(s):  
Takashi ISHIBASHI ◽  
Mitsunobu KITAMURA ◽  
Eiichi MIYAGAWA ◽  
Katsuhisa TOKUMITSU ◽  
Akira TANAKA
Keyword(s):  
Low Density ◽  
Heat Degradation ◽  
Poly Ethylene

Positron Annihilation Studies on the Damp Heat Degradation of ZnO:Al Transparent Conductive Oxide Layers for CIGS Solar Cells

2018 ◽  
Vol 8 (6) ◽  
pp. 1847-1851 ◽  
Author(s):  
Wenqin Shi ◽  
Mirjam Theelen ◽  
Veronique Gevaerts ◽  
Andrea Illiberi ◽  
Nicolas Barreau ◽  
...  
Keyword(s):  
Solar Cells ◽  
Positron Annihilation ◽  
Transparent Conductive Oxide ◽  
Oxide Layers ◽  
Heat Degradation ◽  
Conductive Oxide ◽  
Cigs Solar Cells

Effect of cations on heat degradation of chelator-soluble carrot pectin

1993 ◽  
Vol 20 (3) ◽  
pp. 207-214 ◽  
Author(s):  
T. Sajjaanantakul ◽  
J.P. Van Buren ◽  
D.L. Downing
Keyword(s):  
Heat Degradation

scholarly journals Preparation of lyophilized partial thromboplastin time reagent composed of synthetic phospholipids: usefulness for monitoring heparin therapy

1997 ◽  
Vol 43 (7) ◽  
pp. 1215-1222 ◽  
Author(s):  
Anton M H P van den Besselaar ◽  
Jacoline Neuteboom ◽  
Joyce Meeuwisse-Braun ◽  
Rogier M Bertina
Keyword(s):  
Oral Anticoagulation ◽  
Partial Thromboplastin Time ◽  
Colloidal Silica ◽  
Factor Xa ◽  
Heparin Therapy ◽  
International Committee ◽  
Heat Degradation ◽  
Intravenous Heparin ◽  
Aptt Reagent ◽  
Apparently Healthy

Abstract To contribute to the development of a reference reagent for monitoring heparin therapy, a lyophilized partial thromboplastin time (PTT) reagent was prepared from synthetic dioleoylphosphatidylcholine, dioleoylphosphatidylserine, and dioleoylphosphatidylethanolamine, with colloidal silica as activator. The reagent, coded 91/558, was contained in sealed glass ampoules; it deteriorated in a heat degradation experiment, but its activity remained constant for at least 4 years when stored at −70 °C. Within- and between-run precision with this reagent complied with the requirements proposed by the International Committee for Standardization in Haematology (ICSH) Panel on PTT. The response of this reagent and of two other reagents to heparin added to pooled normal plasma was nonlinear. Citrated samples from 58 patients receiving intravenous heparin and from 24 apparently healthy volunteers were tested with reagent 91/558, with Automated APTT (Organon Teknika), with Manchester APTT reagent, with an anti-factor Xa assay, and with an anti-factor IIa assay. The correlation of APTT with anti-Xa and anti-IIa activity was poor. The best correlation was observed between reagent 91/558 and the Organon Teknika reagent. Correlations were improved when individual patients’ samples were replaced by pooled plasmas from heparinized patients, in whom the effect of oral anticoagulation was minimal. These results suggest that preparation of a lyophilized synthetic phospholipid reagent is feasible for use in monitoring heparin therapy.

scholarly journals Stability-indicating reversed-phase high-performance thin-layer chromatography/densitometry estimation of lafutidine in bulk and tablets

2013 ◽  
Vol 19 (2) ◽  
pp. 213-219 ◽  
Author(s):  
Nitin Prajapati ◽  
Atul Shirkhedkar ◽  
Sanjay Surana
Keyword(s):  
Thin Layer ◽  
Thin Layer Chromatography ◽  
High Performance ◽  
Stress Testing ◽  
Reversed Phase ◽  
Histamine H2 Receptor ◽  
Stability Indicating ◽  
Dry Heat ◽  
Heat Degradation ◽  
Layer Chromatography

Lafutidine (LTD) is a histamine H2 receptor antagonist, with anti-ulcer and mucosal protective activity. A sensitive and selective stability-indicating reversed- phase high -performance thin-layer chromatography (RP-HPTLC)/Densitometry method is suggested for the determination of LTD in the presence of its acid, alkaline, oxidative and dry heat degradation products. Stress testing of LTD was done according to the International Conference on Harmonization (ICH) guidelines in order to validate the stability-indicating power of the analytical procedures. Stress testing demonstrated that LTD underwent acid, alkaline, oxidative and dry heat degradation; on the other hand, it showed stability towards neutral and photo degradation. Chromatography was performed on aluminum-backed silica gel 60 RP-18 F254 S plates with Methanol: Water: Triethylamine 8: 2: 0.5 (v/v) as mobile phase. Densitometric scanning was performed at 276 nm. The system gave compact bands for LTD (Rf 0.67 ? 0.02). Linear regression analysis data for the calibration plots discovered a good linear relationship with r2 > 0.99 in the working concentration range 500 to 3000 ng per band. The limits of detection and quantification were 23.51 ng and 71.26 ng, respectively. The developed method can routinely be used for analysis of LTD in bulk and pharmaceutical formulations.

The impact of selenisation on damp heat degradation of the CIGS back contact molybdenum

2013 ◽  
Author(s):  
Mirjam Theelen ◽  
Mathieu Tomassini ◽  
Nicolas Barreau ◽  
Henk Steijvers ◽  
Annalisa Branca ◽  
...  
Keyword(s):  
Back Contact ◽  
Heat Degradation ◽  
The Impact
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