Low-Oxygen-Saturation Quantification in Human Arterial and Venous Circulation

2009 ◽  
Vol 56 (3) ◽  
pp. 846-854 ◽  
Author(s):  
J. Schoevers ◽  
C. Scheffer ◽  
R. Dippenaar
Keyword(s):  
Oxygen Saturation ◽  
Low Oxygen ◽  
Venous Circulation

scholarly journals Breathing space: deoxygenation of aquatic environments can drive differential ecological impacts across biological invasion stages

2021 ◽  
Author(s):  
James W. E. Dickey ◽  
Neil E. Coughlan ◽  
Jaimie T. A. Dick ◽  
Vincent Médoc ◽  
Monica McCard ◽  
...  
Keyword(s):  
Climate Change ◽  
Oxygen Saturation ◽  
Ecological Impacts ◽  
Neogobius Melanostomus ◽  
Aquatic Environments ◽  
Relative Impact ◽  
Low Oxygen ◽  
Per Capita ◽  
The Impact ◽  
Prey Populations

AbstractThe influence of climate change on the ecological impacts of invasive alien species (IAS) remains understudied, with deoxygenation of aquatic environments often-overlooked as a consequence of climate change. Here, we therefore assessed how oxygen saturation affects the ecological impact of a predatory invasive fish, the Ponto-Caspian round goby (Neogobius melanostomus), relative to a co-occurring endangered European native analogue, the bullhead (Cottus gobio) experiencing decline in the presence of the IAS. In individual trials and mesocosms, we assessed the effect of high, medium and low (90%, 60% and 30%) oxygen saturation on: (1) functional responses (FRs) of the IAS and native, i.e. per capita feeding rates; (2) the impact on prey populations exerted; and (3) how combined impacts of both fishes change over invasion stages (Pre-invasion, Arrival, Replacement, Proliferation). Both species showed Type II potentially destabilising FRs, but at low oxygen saturation, the invader had a significantly higher feeding rate than the native. Relative Impact Potential, combining fish per capita effects and population abundances, revealed that low oxygen saturation exacerbates the high relative impact of the invader. The Relative Total Impact Potential (RTIP), modelling both consumer species’ impacts on prey populations in a system, was consistently higher at low oxygen saturation and especially high during invader Proliferation. In the mesocosm experiment, low oxygen lowered RTIP where both species were present, but again the IAS retained high relative impact during Replacement and Proliferation stages at low oxygen. We also found evidence of multiple predator effects, principally antagonism. We highlight the threat posed to native communities by IAS alongside climate-related stressors, but note that solutions may be available to remedy hypoxia and potentially mitigate impacts across invasion stages.

scholarly journals Mortality Risk Factors in Tetralogy of Fallot Patients Undergoing Total Correction

2021 ◽  
Vol 57 (2) ◽  
pp. 151
Author(s):  
Juliana Juliana ◽  
Yan Efrata Sembiring ◽  
Mahrus Abdur Rahman ◽  
Heroe Soebroto
Keyword(s):  
Risk Factors ◽  
Developing Countries ◽  
Oxygen Saturation ◽  
Tetralogy Of Fallot ◽  
Mortality Risk ◽  
Operative Risk ◽  
Average Height ◽  
Low Oxygen ◽  
Total Correction ◽  
Ventilator Time

A total correction is a preferred treatment for Tetralogy of Fallot patients in every part of the world. However, the mortality in developing countries was as high as 6.9% to 15.3%. This was a retrospective analytic study that analyzed pre and post-operative risk factors that affected mortality on TOF patients that were performed total correction in Indonesia. A total of 47 TOF patients that were performed total correction from January 2016 to September 2019 were enrolled in this study based on the inclusion criteria. Preoperative and post-operative data were obtained from medical records. In this research, the majority of mortality was found in male patients (39.3%), while the female’s rate was lower (36.8%). Overall mortality was 38.3% and one operative death was found. The average age of patients was 84.12 months (12-210 months), whereas the average height (85.56 ± 36.17cm vs. 112.93 ± 21.73) and weight (17.22kg vs. 28.21kg) were lower for mortality patients. Some significant preoperative variables were identified as mortality risk factors such as: age below 60 months (p=0.047), smaller weight and height (p=0.008; p=0.002), abnormal hematocrit (p=0.002), and oxygen saturation below 75% (p=0.018). Significant post-operative risk factors included: temperature above 38.5⁰C (p=0.000), and ventilator time of more than 48 hours (p=0.033). In conclusion, the mortality of TOF patients undergoing a total correction in developing countries was quite high. It was associated with some risk factors, such as younger age, lower weight and height, low oxygen saturation, post-operative fever, and prolonged ventilator time.

scholarly journals COVID-19 in Northeast Bosnia and Herzegovina and patients length of hospitalization

2020 ◽  
Author(s):  
Alma Trnacevic ◽  
Amer Mujkanovic ◽  
Noura Al-Salloum ◽  
Amra Sakusic ◽  
Emir Trnacevic ◽  
...  
Keyword(s):  
Oxygen Saturation ◽  
Bosnia And Herzegovina ◽  
Clinical Factors ◽  
Low Oxygen ◽  
The World ◽  
The Mean ◽  
Elevated Creatinine ◽  
Underlying Diseases ◽  
Time Of Admission ◽  
Length Of Hospitalization

Abstract Background Since outbreak of COVID-19 pandemic clinical data from various parts of the world have been reported, until now there has been no provide data from Bosnia and Herzegovina (B&H) about COVID-19. Aim was to report on the first cohort of patients from B&H and to analyze clinical factors of COVID-19 patients that influence the length of hospitalization. Methods Retrospective cohort study conducted at UKC Tuzla. The study included 25 COVID-19 positive patients that were hospitalized between March 28th and April 27th 2020. The LOH was measured from the time of admission to discharge. Hospitalization greater than 10 days was considered as prolonged. Factors analyzed induced age, BMI, comorbidities, serum creatinine and oxygen saturation upon admission.Results The mean age was 52.92±19.15 years and BMI 28.80±4.22. LOH for patients with normal BMI was 9±SE2.646 days (CI 95% 3.814-14.816) vs 14.182 ±SE .937 (CI 95% 12.346-16.018; p<0.05) for ≥25 BMI. Patients without underlying diseases had a LOH of 11.70 ±SE1.075 (CI 95% 9.592-13.808), while those with comorbidities 14.8 ±SE1.303 (CI95% 12.247-17.353; p<0.05). Conclusion LOH varied among COVID-19 patients and was prolonged when clinical characteristics such as elevated BMI, comorbidities, elevated creatinine and low oxygen saturation levels were taken into consideration. Furthermore, risk factors for COVID-19 patients in B&H do not deviate from data reported in other countries.

scholarly journals Sequestro Leucocitário de Oxigénio

2016 ◽  
Vol 29 (5) ◽  
pp. 343
Author(s):  
Miguel Pinto da Costa ◽  
Henrique Pimenta Coelho
Keyword(s):  
Oxygen Saturation ◽  
Pulse Oximetry ◽  
Arterial Oxygen Saturation ◽  
Gas Analysis ◽  
Lymphocytic Leukemia ◽  
Red Blood Cell Transfusion ◽  
Clinical State ◽  
Arterial Oxygen ◽  
Low Oxygen ◽  
Arterial Blood

<p>The authors present a case of a 60-year-old male patient, previously diagnosed with B-cell chronic lymphocytic leukemia, who was admitted to the Emergency Room with dyspnea. The initial evaluation revealed severe anemia (Hgb = 5.0 g/dL) with hyperleukocytosis (800.000/µL), nearly all of the cells being mature lymphocytes, a normal chest X-ray and a low arterial oxygen saturation (89%; pulse oximetry). After red blood cell transfusion, Hgb values rose (9.0 g/dL) and there was a complete reversion of the dyspnea. Yet, subsequent arterial blood gas analysis, without the administration of supplemental oxygen, systematically revealed very low oxygen saturation values (~ 46%), which was inconsistent with the patient’s clinical state and his pulse oximetry values (~ 87%), and these values were not corrected by the administration of oxygen via non-rebreather mask. The investigation performed allowed to establish the diagnosis of oxygen leukocyte larceny, a phenomenon which conceals the true oxygen saturation due to peripheral consumption by leukocytes.</p>

scholarly journals Effects of low oxygen saturation limits on the ductus arteriosus in extremely low birth weight infants

2009 ◽  
Vol 29 (8) ◽  
pp. 553-557 ◽  
Author(s):  
S Noori ◽  
D Patel ◽  
P Friedlich ◽  
B Siassi ◽  
I Seri ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Oxygen Saturation ◽  
Ductus Arteriosus ◽  
Extremely Low Birth Weight ◽  
Low Oxygen ◽  
Low Birth Weight Infants

scholarly journals Low oxygen saturation during sleep reduces CD1D and RAB20 expressions that are reversed by CPAP therapy

EBioMedicine ◽  
2020 ◽  
Vol 56 ◽  
pp. 102803
Author(s):  
Tamar Sofer ◽  
Ruitong Li ◽  
Roby Joehanes ◽  
Honghuang Lin ◽  
Adam C. Gower ◽  
...  
Keyword(s):  
Oxygen Saturation ◽  
Cpap Therapy ◽  
Low Oxygen

Comparison of buffer and red blood cell perfusion of guinea pig heart oxygenation

2003 ◽  
Vol 285 (5) ◽  
pp. H1819-H1825 ◽  
Author(s):  
Kenneth A. Schenkman ◽  
Daniel A. Beard ◽  
Wayne A. Ciesielski ◽  
Eric O. Feigl
Keyword(s):  
Oxygen Consumption ◽  
Guinea Pig ◽  
Oxygen Saturation ◽  
Red Blood Cells ◽  
Ventricular Function ◽  
Oxygen Tension ◽  
Blood Cells ◽  
Low Oxygen ◽  
Guinea Pig Heart ◽  
Perfused Hearts

Myocardial mean myoglobin oxygen saturation was determined spectroscopically from isolated guinea pig hearts perfused with red blood cells during increasing hypoxia. These experiments were undertaken to compare intracellular myoglobin oxygen saturation in isolated hearts perfused with a modest concentration of red blood cells (5% hematocrit) with intracellular myoglobin saturation previously reported from traditional buffer-perfused hearts. Studies were performed at 37°C with hearts paced at 240 beats/min and a constant perfusion pressure of 80 cmH2O. It was found that during perfusion with a hematocrit of 5%, baseline mean myoglobin saturation was 93% compared with 72% during buffer perfusion. Mean myoglobin saturation, ventricular function, and oxygen consumption remained fairly constant for arterial perfusate oxygen tensions above 100 mmHg and then decreased precipitously below 100 mmHg. In contrast, mean myoglobin saturation, ventricular function, and oxygen consumption began to decrease even at high oxygen tension with buffer perfusion. The present results demonstrate that perfusion with 5% red blood cells in the perfusate increases the baseline mean myoglobin saturation and better preserves cardiac function at low oxygen tension relative to buffer perfusion. These results suggest that caution should be used in extrapolating intracellular oxygen dynamics from buffer-perfused to blood-perfused hearts.

scholarly journals Efektivitas Pemberian Oksigen Posisi Semi Fowler Dan Fowler Terhadap Perubahan Saturasi Pada Pasien Asma Bronkial Persisten Ringan

JKEP ◽  
2019 ◽  
Vol 4 (1) ◽  
pp. 31-43
Author(s):  
Syamsul Firdaus ◽  
Misbachul Munirul Ehwan ◽  
Agus Rachmadi
Keyword(s):  
Oxygen Saturation ◽  
Bronchial Asthma ◽  
Oxygen Therapy ◽  
Sampling Technique ◽  
T Test ◽  
Low Oxygen ◽  
Asthma Attack ◽  
Asthma Patients ◽  
The Difference ◽  
Persistent Bronchial Asthma

Mild persistent bronchial asthma is a chronic inflammatory airway that cause the low oxygen saturation value (91-95%). Administering oxygen therapy, setting the position of the semi fowler and fowler can reduce the risk of a decreased chest configuration. This research aims to assess the difference of effectiveness of administering oxygen at semi fowler with fowler position to the saturation changes in mild persistent bronchial asthma patients in Ratu Zalecha Martapura Hospital. This research method is quasy Experiment. The population research are all patients who experience mild persistent bronchial asthma attack, the sample of this research are 20 respondents with purposive sampling technique and analyzed with independent T test. The results is at semi fowler position the average of oxygen saturation before the treatment is 93.10%, after administering oxygen therapy with semi fowler position the average saturation is 98.00%. At the fowler position the average of oxygen saturation before the treatment is 92.60%, after administering oxygen therapy with fowler position the average saturation is 98.00%. The independent T-test result showed no difference of effectiveness of administering oxygen at semi fowler with fowler position to the saturation changes in mild persistent bronchial asthma patients,so teh patients can be given both positions.

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