Cost-effective system-level test strategies

Author(s):  
D. Farren ◽  
A.P. Ambler
Author(s):  
George Kornaros ◽  
Ioannis Christoforakis ◽  
Othon Tomoutzoglou ◽  
Dimitrios Bakoyiannis ◽  
Kallia Vazakopoulou ◽  
...  

2019 ◽  
Vol 13 (1) ◽  
pp. 266-271
Author(s):  
Georgina Kakra Wartemberg ◽  
Thomas Goff ◽  
Simon Jones ◽  
James Newman

Aims: To create a more effective system to identify patients in need of revision surgery. Background: There are over 160,000 total hip and knee replacements performed per year in England and Wales. Currently, most trusts review patients for up to 10 years or more. When we consider the cost of prolonged reviews, we cannot justify the expenditure within a limited budget. Study Design & Methods: We reviewed all patients' notes that underwent primary hip and knee revision surgery at our institution, noting age, gender, symptoms at presentation, referral source, details of the surgery, reason for revision and follow up history from primary surgery. Results: There were 145 revision arthroplasties (60 THR and 85 TKR) that met our inclusion criteria. Within the hip arthroplasty group, indications for revision included aseptic loosening (37), dislocation (10), and infection (3), periprosthetic fracture, acetabular liner wear and implant failure. All thirty-seven patients with aseptic loosening presented with pain. Twenty-five were referred from general practice with new symptoms. The remaining were clinic follow-ups. The most common reason for knee revision was aseptic loosening (37), followed by infection (21) and then progressive osteoarthritis (8). Most were referred from GP as a new referral or were clinic follow-ups. All patients were symptomatic. Conclusion: All the patients that underwent revision arthroplasty were symptomatic. Rather than yearly follow up, we recommend a cost-effective system. We are implementing a 'non face-to-face' system. Patients would be directly sent a questionnaire and x-ray form. The radiographs and forms will be reviewed by an experienced arthroplasty surgeon. The concerning cases will be seen urgently in a face-to-face clinic.


Author(s):  
Nikolay I. Dorogov ◽  
Ivan A. Kapitonov ◽  
Nazygul T. Batyrova

2011 ◽  
Vol 7 (2) ◽  
pp. 147-174
Author(s):  
Steven J. Hoffman ◽  
Lorne Sossin

AbstractAdjudicative tribunals are an integral part of health system governance, yet their real-world impact remains largely unknown. Most assessments focus on internal accountability and use anecdotal methodologies; few, studies if any, empirically evaluate their external impact and use these data to test effectiveness, track performance, inform service improvements and ultimately strengthen health systems. Given that such assessments would yield important benefits and have been conducted successfully in similar settings (e.g. specialist courts), their absence is likely attributable to complexity in the health system, methodological difficulties and the legal environment within which tribunals operate. We suggest practical steps for potential evaluators to conduct empirical impact evaluations along with an evaluation matrix template featuring possible target outcomes and corresponding surrogate endpoints, performance indicators and empirical methodologies. Several system-level strategies for supporting such assessments have also been suggested for academics, health system institutions, health planners and research funders. Action is necessary to ensure that policymakers do not continue operating without evidence but can rather pursue data-driven strategies that are more likely to achieve their health system goals in a cost-effective way.


2011 ◽  
Vol 60 (3) ◽  
pp. 187-201 ◽  
Author(s):  
ANNA L. BOREK ◽  
JOANNA WILEMSKA ◽  
RADOSŁAW IZDEBSKI ◽  
WALERIA HRYNIEWICZ ◽  
IZABELA SITKIEWICZ

Streptococcus pyogenes (group A Streptococcus, GAS) is a human pathogen that causes diseases of various intensity, from mild strep throat to life threatening invasive infections and postinfectional sequelae. S. pyogenes encodes multiple, often phage encoded, virulence factors and their presence is related to severity of the disease. Acquisition of mobile genetic elements, carrying virulence factors, as phages or ICEs (integrative and cojugative elements) has been shown previously to promote selection of virulent clones. We designed the system of eight low volume multi- and one singleplex PCR reactions to detect genes encoding twenty virulence factors (spd3, sdc, sdaB, sdaD, speB, spyCEP, scpA, mac, sic, speL, K, M, C, I, A, H, G, J, smeZ and ssa) and twenty one phage and ICE integration sites described so far for S. pyogenes. Classification of strains based on the phage and virulence factors absence or presence, correlates with PFGE MLST and emm typing results. We developed a novel, fast and cost effective system that can be used to detect GAS virulence factors. Moreover, this system may become an alternative and effective system to differentiate between GAS strains.


Sensors ◽  
2020 ◽  
Vol 20 (3) ◽  
pp. 613
Author(s):  
David Safadinho ◽  
João Ramos ◽  
Roberto Ribeiro ◽  
Vítor Filipe ◽  
João Barroso ◽  
...  

The capability of drones to perform autonomous missions has led retail companies to use them for deliveries, saving time and human resources. In these services, the delivery depends on the Global Positioning System (GPS) to define an approximate landing point. However, the landscape can interfere with the satellite signal (e.g., tall buildings), reducing the accuracy of this approach. Changes in the environment can also invalidate the security of a previously defined landing site (e.g., irregular terrain, swimming pool). Therefore, the main goal of this work is to improve the process of goods delivery using drones, focusing on the detection of the potential receiver. We developed a solution that has been improved along its iterative assessment composed of five test scenarios. The built prototype complements the GPS through Computer Vision (CV) algorithms, based on Convolutional Neural Networks (CNN), running in a Raspberry Pi 3 with a Pi NoIR Camera (i.e., No InfraRed—without infrared filter). The experiments were performed with the models Single Shot Detector (SSD) MobileNet-V2, and SSDLite-MobileNet-V2. The best results were obtained in the afternoon, with the SSDLite architecture, for distances and heights between 2.5–10 m, with recalls from 59%–76%. The results confirm that a low computing power and cost-effective system can perform aerial human detection, estimating the landing position without an additional visual marker.


2011 ◽  
Vol 480-481 ◽  
pp. 1302-1307
Author(s):  
Shou Cheng Ding ◽  
Wen Hui Li ◽  
Shi Zhou Yang

Microprocessors and sensor technology together achieved a fully automatic washing machine based on fuzzy control. System used an integrated mixed-signal system-level C8051F020 microcontroller. The system would detect and reasoning on the amount of washing objects, fabricl quality, water level, reference washing time, the flow intensity, real-time temperature and dirt level of washing liquid, so as to achieve automatically complete the whole washing process. Experiments shows that the system is stable, easy to operate, cost-effective advanced features, so that it has a certain value.


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