Hair as a matrix in monitoring drug epilepsy therapy

Author(s):  
Alicja Zakrzewska ◽  
Michał Dermanowski ◽  
Paweł Mierzejewski ◽  
Julita Kuczyńska



2020 ◽  
Vol 12 ◽  
Author(s):  
João Mauricio Castaldelli-Maia ◽  
Felipe Gil ◽  
Antonio Ventriglio ◽  
Julio Torales ◽  
Ligia Florio ◽  
...  

Background: As one of the forms of media and art most consumed in the world, Oscar-nominated movies should have their drug use representation monitored because of possibly influencing but also reflecting society’s behavior. Objective: To investigate drug use representation in scenes from movies nominated for the Academy Awards (Oscar) from 2008-2011, through media content analysis. Methods: 437 scenes from Oscar-nominated movies (best film, best actor and best actress categories) showing drug consumption and/or its effects were assessed. Each drug represented and identified in a given scene (i.e., drug use incident) was counted as a unit for the present study (n = 515). Survey settings were used to control for over- or under-estimation of the prevalence of a variable in a given year or movie. Results: All the Oscar-nominated movies portrayed at least one scene of drug use. There was a massive predominance of alcohol and tobacco in movies, with a high use among men who also use drugs, habitually or occasionally, but related to stress/tension, predominantly at home. However, there was a significant progressive increase in the use of drugs other than alcohol and tobacco, multiple drugs, and by women. Conclusion: These findings echo epidemiological studies on substance use in western countries, an overall trend towards greater home drug use representation and gender convergence since 1970, which increased since 2000. Monitoring drug use representation in Oscar-nominated movies may represent an important public health tool.



1994 ◽  
Vol 32 (1) ◽  
pp. 57-65 ◽  
Author(s):  
Steven K. Koester ◽  
Juhani U. Maenpaa ◽  
Valerie J. Wiebe ◽  
W. Jeffrey Baker ◽  
Gregory T. Wurz ◽  
...  


1988 ◽  
Vol 10 (4) ◽  
pp. 23-27
Author(s):  
Stanley N. Cohen ◽  
Jing-Jing L. Kondo ◽  
Richard J. Mangini ◽  
Terrence N. Moore ◽  
Ann Barry Flood


Small ◽  
2018 ◽  
Vol 14 (38) ◽  
pp. 1802307 ◽  
Author(s):  
Joanna Boucard ◽  
Camille Linot ◽  
Thibaut Blondy ◽  
Steven Nedellec ◽  
Philippe Hulin ◽  
...  


2005 ◽  
Vol 152 (1) ◽  
pp. H6 ◽  
Author(s):  
Audrey M. Johnson ◽  
Donald R. Sadoway ◽  
Michael J. Cima ◽  
Robert Langer


Molecules ◽  
2021 ◽  
Vol 26 (23) ◽  
pp. 7185
Author(s):  
Oliver Gould ◽  
Natalia Drabińska ◽  
Norman Ratcliffe ◽  
Ben de Lacy Costello

Mass spectrometry (MS) is an analytical technique that can be used for various applications in a number of scientific areas including environmental, security, forensic science, space exploration, agri-food, and numerous others. MS is also continuing to offer new insights into the proteomic and metabolomic fields. MS techniques are frequently used for the analysis of volatile compounds (VCs). The detection of VCs from human samples has the potential to aid in the diagnosis of diseases, in monitoring drug metabolites, and in providing insight into metabolic processes. The broad usage of MS has resulted in numerous variations of the technique being developed over the years, which can be divided into hyphenated and real-time MS techniques. Hyphenated chromatographic techniques coupled with MS offer unparalleled qualitative analysis and high accuracy and sensitivity, even when analysing complex matrices (breath, urine, stool, etc.). However, these benefits are traded for a significantly longer analysis time and a greater need for sample preparation and method development. On the other hand, real-time MS techniques offer highly sensitive quantitative data. Additionally, real-time techniques can provide results in a matter of minutes or even seconds, without altering the sample in any way. However, real-time MS can only offer tentative qualitative data and suffers from molecular weight overlap in complex matrices. This review compares hyphenated and real-time MS methods and provides examples of applications for each technique for the detection of VCs from humans.



2014 ◽  
Vol 27 (11) ◽  
pp. 1267-1274 ◽  
Author(s):  
Cyril Lorenzato ◽  
Chris Oerlemans ◽  
Alexandru Cernicanu ◽  
Mario Ries ◽  
Baudouin Denis de Senneville ◽  
...  


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