scholarly journals Early Plasmodium -induced inflammation does not accelerate aging in mice

2018 ◽  
Vol 12 (2) ◽  
pp. 314-323 ◽  
Author(s):  
Cédric Lippens ◽  
Emmanuel Guivier ◽  
Sarah E. Reece ◽  
Aidan J. O’Donnell ◽  
Stéphane Cornet ◽  
...  
Keyword(s):  
Polymers ◽  
2021 ◽  
Vol 13 (13) ◽  
pp. 2119
Author(s):  
Lin Yu ◽  
Shiman Liu ◽  
Weiwei Yang ◽  
Mengying Liu

In order to elucidate the aging performance and aging mechanism of a rubber waterstop in low-temperature environments, the rubber waterstops were placed in the freezing test chamber to accelerate aging, and then we tested its tensile strength, elongation, tear strength, compression permanent deformation and hardness at different times. Additionally, the damaged specimens were tested by scanning electron microscope, Fourier transform infrared spectroscopy and energy dispersive spectrometry. The results showed that with the growth of aging time, the mechanical properties of the rubber waterstop are reduced. At the same time, many protrusions appeared on the surface of the rubber waterstop, the C element gradually decreased, and the O element gradually increased. During the period of 72–90 days, the content of the C element in the low-temperature air environment significantly decreased compared with that in low-temperature water, while the content of O element increased significantly.


2007 ◽  
Vol 75 (3) ◽  
pp. 521-528 ◽  
Author(s):  
Tian-Wu Qiao ◽  
Na Liu ◽  
De-Qiang Miao ◽  
Xia Zhang ◽  
Dong Han ◽  
...  

2014 ◽  
Vol 955-959 ◽  
pp. 326-334 ◽  
Author(s):  
Peng Wan ◽  
Cheng Xi Wei ◽  
Jian Long Wu ◽  
Qing Hua Jin

Edible salt (ES) is also thought to exacerbate the symptoms of Alzheimer, however, the in vivo function of ES remains poorly understand. In this work, we investigated the phenomenon using the model of Alzheimer induced by D-gal. The behavious examination results exhibited that D-gal plus ES can weaken spatial memory function in the Morris water maze; the activities of T-SOD, GSH-Px and the CAT level in both hippocampus and cortex showed that D-gal plus ES decreased the expression of T-SOD and GSH-Px, but the expression of CAT increased, the protein expression determined in both of the hippocampus and cortex demonstrated that COX-2, iNOS, NFκ-B-p65-N proteins were significantly increased. It is possible that ES acts through several mechanisms, mediating a potential role in memory damage in mice. These results suggest that further study is necessary to evaluate the effect of salt on damage of memory and to determine the molecular mechanisms.


Science ◽  
2015 ◽  
Vol 347 (6220) ◽  
pp. 362-362 ◽  
Author(s):  
G. Vogel
Keyword(s):  

2011 ◽  
Vol 26 (S2) ◽  
pp. 567-567
Author(s):  
A.S. Ferreira ◽  
N.R.B. Raposo ◽  
E.M.S. Barbosa ◽  
W.F. Gattaz

IntroductionAccelerate aging is a worldwide problem. In underdeveloped countries, it is occurring without adequate planning and is attributed due to falling mortality and fertility, which contributed to increase life expectancy. However, aging was not accompanied by improvement in living conditions and health assistance. Poor sanitation and diet, low incomes and education levels contributed to increasing the prevalence of chronic diseases in elderly.ObjectivesData obtained in other countries could not represent the national population; objective was to describe a Brazilian frailty elderly sample.AimsDetermine cognitive impairment prevalence in Brazilian frailty elderly.Methods1952 frailty elderly were analyzed. Social data, tobacco and alcohol consumption were verified and mini-mental state examination was applied from February to August in 2010.ResultsFemale elderly was predominant (68.8%). They were almost married (47.5%), followed by widow (37%), single (8.1%), divorced (7.4%). White people were predominant (69.2%); black (14.6%) and brown (16.2%) were presented at the same proportion. 823 frailty elderly (64.9%) studied until 4 years; 7.7% studied between 4–8 years; 1.9% went to college and 25.6% were illiterate. Only 10.6% were smokers and 2.8% drank alcohol. The majority (79.4%) were younger than 80 years-old. Cognitive impairment prevalence were 17.2% in illiterate; 15.2% in elderly who studied until 4 years and lower, 5.3%, in the group who studied between 4–8 years.ConclusionsThe prevalence of cognitive impairment was dependent on years of study and we presented data obtained in a Brazilian sample. These data can be used to compare cognitive impairment in different countries.


2020 ◽  
Vol 45 (3) ◽  
pp. 126-133
Author(s):  
Jung Yun Kang ◽  
◽  
Namju Kang ◽  
Dong Min Shin ◽  
Yu-Mi Yang
Keyword(s):  

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Roger Pamphlett

AbstractSuccessful aging is likely to involve both genetic and environmental factors, but environmental toxicants that accelerate aging are not known. Human exposure to mercury is common, and mercury has genotoxic, autoimmune, and free radical effects which could contribute to age-related disorders. The presence of inorganic mercury was therefore assessed in the organs of 170 people aged 1–104 years to determine the prevalence of mercury in human tissues at different ages. Mercury was found commonly in cells of the brain, kidney, thyroid, anterior pituitary, adrenal medulla and pancreas. The prevalence of mercury in these organs increased during aging but decreased in people aged over 80 years. People with mercury in one organ usually also had mercury in several others. In conclusion, the prevalence of inorganic mercury in human organs increases with age. The relative lack of tissue mercury in the very old could account for the flattened mortality rate and reduced incidence of cancer in this advanced age group. Since mercury may accelerate aging, efforts to reduce atmospheric mercury pollution could improve the chances of future successful aging.


2013 ◽  
Vol 753-755 ◽  
pp. 823-828
Author(s):  
Jian Zhang ◽  
Yue Jin Fu ◽  
Hai Xia Yu ◽  
Shao Fei Yuan

In this study, bamboo ply panel (BPP) was exposed to 5 kinds of accelerate aging cycles in order to assess its durability under extreme conditions. Meanwhile, outdoor weathering, as a comparison, was carried out for 36 months with the objective of evaluating humidity resistance by means of testing modules of rupture (MOR) and modules of elasticity (MOE) value. Results show that for each kind of laboratory aging process, a comparison to wild field weathering was possible. Though very susceptible to hydrothermal alternation, BPP still kept good performance, the life span was about 15 months.


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