Atypical clinical presentations of Malassezia folliculitis: a retrospective analysis of 94 biopsy-proven cases

2018 ◽  
Vol 57 (3) ◽  
pp. e19-e20 ◽  
Author(s):  
Yi-Chiun Tsai ◽  
Jen-Yu Wang ◽  
Yu-Hung Wu ◽  
Yen-Jen Wang
2021 ◽  
Vol 10 (2) ◽  
pp. 201
Author(s):  
Filippo Ricciardiello ◽  
Salvatore Mazzone ◽  
Giuseppe Longo ◽  
Giuseppe Russo ◽  
Enrico Piccirillo ◽  
...  

Temporal bone fractures are a common lesion of the base of the skull. The diagnosis and management of temporal bone fractures require a multidisciplinary approach. Variable clinical presentations may arise from such fractures, ranging from an asymptomatic course to very serious consequences. The aim of this study was to report our experience with a series of patients with temporal bone fractures and to propose a diagnostic/therapeutic algorithm. This study enrolled 141 patients, 96 (68.1%) males and 45 (31.9%) females, ranging in age from 20 to 60 (average age: 39 ± 4.1 years), with temporal bone fractures who were referred to Cardarelli Hospital between 2006 and 2018. The present paper presents a classification of temporal bone fractures and typical clinical sequelae and provides an illustration of their prognosis and treatment.


2015 ◽  
Vol 6 (5) ◽  
pp. 31-35 ◽  
Author(s):  
Monojit Mondal ◽  
Biswajit Biswas ◽  
Atanu Roy ◽  
Sumanta Laha ◽  
Rajib Das ◽  
...  

Background: Neurocysticercosis (NCC) is a common, widely prevalent parasitic infestation of the central nervous system in children of developing countries leading to neurological morbidities. Objectives: To study the variability of initial clinical presentations and brain imaging findings in children with NCC in the rural population of West Bengal. Methods: A retrospective analysis was done in the Department of Pediatric Medicine, Burdwan Medical College, Burdwan, India from August 2011 to August 2013. Results: Out of 952 admitted children with seizure, 113 children were diagnosed as having NCC (11.9%). Out of them, 62 (54.9%) were boys and 51 (45.1%) were girls. The age of presentation varied from 3 years to 12 years, with mean age 9.4 years. The commonest age of presentation was between 10 to 12 years (n=62; 54.9%). The maximum number of patients were from Burdwan district (n=72; 63.7%) followed by Birbhum (n=25; 22.1%). The commonest initial presentation with seizure (n=93; 82.3 %); partial seizure were present in 76 patients (81.7%). On brain imaging study, the commonest location of lesions was found in the parietal region (n=69; 61.1 %), the right parietal region being more common. Single lesions were found in 102 patients(90.3%). Conclusion: NCC is a major cause of neurological morbidity in children of developing nations and it should be suspected in any children presenting with a first episode of afebrile partial seizure. A screening brain imaging should be performed earlier to prevent undue mortality and morbidity.DOI: http://dx.doi.org/10.3126/ajms.v6i5.11628 Asian Journal of Medical Sciences Vol.6(5) 2015 31-35   


2017 ◽  
Vol 9 (04) ◽  
pp. 288-295 ◽  
Author(s):  
Teena Wadhwa ◽  
Usha Baveja ◽  
Navin Kumar ◽  
Deepak Govil ◽  
Sharmila Sengupta

Abstract PURPOSE: The aim of this study is to evaluate the predisposing risk factors, clinical presentations, laboratory parameters, and treatments taken and outcomes in patients of nocardiosis in the span of 5 years in a tertiary care hospital. MATERIALS AND METHODS: The patients whose specimens showed Nocardia like organism in Gram-staining, Kinyoun staining and characteristic colonies in culture were included in the retrospective analysis study. Retrospective analysis of associated risk factors, clinical presentations, and radiological findings was performed. RESULTS: Of the thirteen patients, 11 (76.9%) had immunosuppressive pathologies including solid organ transplantation, autoimmune disease, use of steroids, and immunosuppressive drugs as important risk factors. Four types of clinical manifestations were observed, pulmonary (46.1%), cutaneous (23.07%), cerebral (15.3%), and bacteremia (15.3%). The most common presentation was pulmonary with steroid therapy as a significant risk factor. Consolidation and pleural effusion were the common radiological findings in these cases. In eight of the nine patients anti-nocrdial drugs were given. Cotrimoxazole as monotherapy was given in four cases (44.44%), cotrimoxazole in combination with meropenem in two cases (22.22%); minocycline and linezolid were given in one case each. The overall mortality was 36.36% and was seen in patients with pulmonary nocardiosis. CONCLUSIONS: The study indicates that Nocardial infections are re-emerging on account of an increase in numbers of immunocompromised patients due to increased organ transplants, autoimmune diseases, malignancies, and use of immunosuppressive drugs and steroids. The diagnosis is often missed/not suspected and delayed because of the clinical resemblance to many other infections. Nocardial infection should be suspected and assessed particularly in immunocompromised patients not responding to treatment/improving clinically.


2019 ◽  
Vol 4 (3) ◽  
pp. 83-86
Author(s):  
Manjit Kaur Rana ◽  
Karuna Singh ◽  
M K Mahajan ◽  
Amrit Pal Singh Rana

Context: Cervical cancer is a malignant neoplasm arising mainly in the transformation zone of the cervix. Cervical cancer is the second most common cancer among women worldwide after breast cancer. Squamous cell carcinoma and adenocarcinoma constitute the greatest burden, globally as well as in India.Aims: The current study was aimed to assess the histopathological profile and its correlation with clinical findings.Settings and Design: It was a retrospective analysis of the patients of cervical carcinoma. Methods and Materials: The retrospective analysis of histopathological patterns of carcinoma cervix was done. A total of 120 cervical biopsies were received, amongst which 5 biopsies were chronic cervicitis, 9 were cervical intraepithelial neoplasia (CIN) and 106 cases were of carcinoma. Further histologic subtyping of cervical carcinoma was done and was correlated with clinical presentations and stage. The collected data were analysed. Statistical analysis used: Analysis of data was done for simple means and percentages.Results: The most common age group in carcinoma cervix was fifth and sixth decade with history of bleeding per vagina being the most common clinical presentation. Squamous cell carcinoma (SCC) was the most common variant, ≥Stage III case constituted in majority and also showed poor prognosis.Conclusion: A majority of Indian women presented at later stages of cervical cancer, hence demanding the need of dedicated screening programes. Many variants present with different clinical findings especially as deep infiltrative growth patterns, hence histologic types should be kept in mind clinically while dealing with unfamiliar clinical presentations. In our experience most of the women presented in later stages and patients with ≥ stage III showed poor prognosis.


Author(s):  
Julie L. Wambaugh ◽  
Lydia Kallhoff ◽  
Christina Nessler

Purpose This study was designed to examine the association of dosage and effects of Sound Production Treatment (SPT) for acquired apraxia of speech. Method Treatment logs and probe data from 20 speakers with apraxia of speech and aphasia were submitted to a retrospective analysis. The number of treatment sessions and teaching episodes was examined relative to (a) change in articulation accuracy above baseline performance, (b) mastery of production, and (c) maintenance. The impact of practice schedule (SPT-Blocked vs. SPT-Random) was also examined. Results The average number of treatment sessions conducted prior to change was 5.4 for SPT-Blocked and 3.9 for SPT-Random. The mean number of teaching episodes preceding change was 334 for SPT-Blocked and 179 for SPT-Random. Mastery occurred within an average of 13.7 sessions (1,252 teaching episodes) and 12.4 sessions (1,082 teaching episodes) for SPT-Blocked and SPT-Random, respectively. Comparisons of dosage metric values across practice schedules did not reveal substantial differences. Significant negative correlations were found between follow-up probe performance and the dosage metrics. Conclusions Only a few treatment sessions were needed to achieve initial positive changes in articulation, with mastery occurring within 12–14 sessions for the majority of participants. Earlier occurrence of change or mastery was associated with better follow-up performance. Supplemental Material https://doi.org/10.23641/asha.12592190


2003 ◽  
Vol 8 (5) ◽  
pp. 4-12
Author(s):  
Lorne Direnfeld ◽  
James Talmage ◽  
Christopher Brigham

Abstract This article was prompted by the submission of two challenging cases that exemplify the decision processes involved in using the AMA Guides to the Evaluation of Permanent Impairment (AMA Guides). In both cases, the physical examinations were normal with no evidence of illness behavior, but, based on their histories and clinical presentations, the patients reported credible symptoms attributable to specific significant injuries. The dilemma for evaluators was whether to adhere to the AMA Guides, as written, or to attempt to rate impairment in these rare cases. In the first case, the evaluating neurologist used alternative approaches to define impairment based on the presence of thoracic outlet syndrome and upper extremity pain, as if there were a nerve injury. An orthopedic surgeon who evaluated the case did not base impairment on pain and used the upper extremity chapters in the AMA Guides. The impairment ratings determined using either the nervous system or upper extremity chapters of the AMA Guides resulted in almost the same rating (9% vs 8% upper extremity impairment), and either value converted to 5% whole person permanent impairment. In the second case, the neurologist evaluated the individual for neuropathic pain (9% WPI), and the orthopedic surgeon rated the patient as Diagnosis-related estimates Cervical Category II for nonverifiable radicular pain (5% to 8% WPI).


2016 ◽  
Vol 22 ◽  
pp. 145-146
Author(s):  
Tiffany Schwasinger-Schmidt ◽  
Georges Elhomsy ◽  
Fanglong Dong ◽  
Bobbie Paull-Forney

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