Comparison of sun protection factors determined by an in vivo and different in vitro methodologies: a study with 58 different commercially available sunscreen products

2004 ◽  
Vol 26 (2) ◽  
pp. 79-89 ◽  
Author(s):  
U. Heinrich ◽  
H. Tronnier ◽  
D. Kockott ◽  
R. Kuckuk ◽  
H. M. Heise
Keyword(s):  
Sun Protection ◽  
Sunscreen Products

In Vitro Evaluation of Sun Protection Factor of Plant Extracts By Ultraviolet Spectroscopy Method

2021 ◽  
Vol 1 (30) ◽  
pp. 58-62
Author(s):  
Geeta Bhandari Garima Negi
Keyword(s):  
Chronic Exposure ◽  
Sun Protection ◽  
Skin Protection ◽  
Murraya Koenigii ◽  
Protection Factor ◽  
Safe Alternative ◽  
Sun Protection Factor ◽  
Acute And Chronic Exposure ◽  
Sunscreen Products

Abstract-Acute and chronic exposure to nonphysiological doses of ultraviolet radiation leads to variety of changes of skin ranging from sun-burn, erythema to skin cancer. For skin protection from deleterious effects of sunlight, sunscreen products are used in various forms having chemical and physical filters. However, synthetic sunscreen formulations are reported to cause adverse effects. Thus the present study was planned to evaluate the sun protection factor (SPF) of leaves extract of Murraya koenigii for their application as herbal sunscreens. The results suggested that the occurrence of active compounds responsible for ultraviolet absorption can be extracted for use in sunscreens preparations as better, cheaper and safe alternative to harmful chemical sunscreens. Keywords: UV radiations, SPF, Murraya koenigii

Correlation of in vivo and in vitro measurements of sun protection factor

2020 ◽  
Vol 11 (2) ◽  
Author(s):  
M.-T. Sheu ◽  
C.-W. Lin ◽  
M.-C. Huang ◽  
C.-H. Shen ◽  
H.-O. Ho
Keyword(s):  
Sun Protection ◽  
Protection Factor ◽  
In Vitro Measurements ◽  
Sun Protection Factor

scholarly journals Use of Vegetable Oils to Improve the Sun Protection Factor of Sunscreen Formulations

Cosmetics ◽  
2019 ◽  
Vol 6 (2) ◽  
pp. 25 ◽  
Author(s):  
Lucia Montenegro ◽  
Ludovica Santagati
Keyword(s):  
Vegetable Oils ◽  
Sun Protection ◽  
Biological Properties ◽  
Uv Filters ◽  
Protection Factor ◽  
Hydrophilic Lipophilic Balance ◽  
Sun Protection Factor ◽  
Sunscreen Products ◽  
Organic Uv Filters

Some vegetable oils have many biological properties, including UV-absorbing capacity. Therefore, their use has been suggested to reduce the content of organic UV-filters in sunscreen products. In this work, we investigated the feasibility of developing oil-based vehicles with a high sun protection factor (SPF) using pomegranate oil (PMG) and shea oil (BPO) in association with different percentages of organic UV-filters (octyl– methoxycinnamate, butyl methoxydibenzoylmethane, and bemotrizinol). We characterized the spreadability, occlusion factor, pH, and required hydrophilic lipophilic balance of the resulting formulations, and did not observe relevant differences due to the incorporation of vegetable oils. The in vitro spectrophotometric determinations of SPF values highlighted that the addition of BPO (1% (w/w)) and PMG (1% (w/w)) resulted in an increase in SPF in comparison with the same formulations that contained only organic UV-filters. The SPF increase was more significant for the formulations that contained lower amounts of organic UV-filters. The results of this study supported the hypothesis that including suitable vegetable oils in sunscreen formulations could be a promising strategy to design products with a lower content of organic UV-filters.

scholarly journals In-vitro and In-vivo Determinations of Sun Protection Factors (SPF) of Skin Lotions Containing Mountain Papaya Fruit and Mangosteen Peel Ethanolic Extract

2020 ◽  
Vol 25 (3) ◽  
Author(s):  
Heru Sasongko ◽  
Natasya Advaita ◽  
Ratih Guswinda Lestari ◽  
Karimah Umar Aidid
Keyword(s):  
Sun Exposure ◽  
Sun Protection ◽  
In Vitro Test ◽  
Garcinia Mangostana ◽  
In Vivo Test ◽  
Antioxidants Activity ◽  
Mangosteen Peel ◽  
Vitro Test

Indonesia is a high sun exposure country. Exposure to ultraviolet (UV) causes various kinds of skin disorders such as erythema, sunburn, aging, and cancer. Mountain papaya fruit (Vasconcellea pubescens A.DC.) and mangosteen peel (Garcinia mangostana L.) contains metabolite compounds that can protect the skin from sunlight because of its antioxidants activity. The purpose of this study to determine whether the combination of the mountain papaya fruit and mangosteen peel extracts in skin lotion can be used as sun protectors through the in-vitro and in-vivo study. The experiment was done by extracting the mountain papaya fruit and mangosteen peel through the maceration method. The extracts were formulated into skin lotion in three different formulas with the ratio of mountain papaya fruit extract: mangosteen peel extract as follows F1(1:1), F2(1:3), and F3(3:1). In vitro test was done by using UV-VIS spectrophotometry to determine the SPF value and in vivo test was used erythema-induced rats by exotera beam light. The result of in vitro test gained a high enough SPF value for all three formulas F1=23,23; F2=21,70 and F3=28,64 and the result of in vivo test showed that all three formulas did not indicate the existence of erythema value.         It can be concluded that three skin lotion formulas containing mountain papaya fruit and mangosteen peel ethanol extract have the effect of sun protection.

Evaluation of Sun Protection Factor of Cosmetic Formulations by a Simple Visual In Vitro Method Mimicking the In Vivo Method

2012 ◽  
Vol 101 (2) ◽  
pp. 726-732 ◽  
Author(s):  
Leonardo R. de Paula ◽  
André L.A. Parussulo ◽  
Koiti Araki ◽  
Henrique E. Toma
Keyword(s):  
Sun Protection ◽  
Protection Factor ◽  
In Vitro Method ◽  
Cosmetic Formulations ◽  
Sun Protection Factor

scholarly journals Aktivitas Perlindungan Tabir Surya Secara In Vitro Dari Ekstrak Etanol Kulit Buah, Kulit Biji dan Biji Pinang Yaki (Areca vestiaria Giseke)

Jurnal MIPA ◽  
2017 ◽  
Vol 6 (2) ◽  
pp. 46
Author(s):  
Irmawati Anggriani ◽  
Max R.J. Runtuwenen ◽  
Vanda S. Kamu
Keyword(s):  
Ethanol Extract ◽  
Sun Protection ◽  
Protection Factor ◽  
Rotary Evaporator ◽  
Three Samples ◽  
Maximum Protection ◽  
Sun Protection Factor ◽  
Protection Activity

Penelitian ini bertujuan untuk menguji aktivitas perlindungan tabir surya dari ekstrak etanol kulit buah, kulit biji dan biji pinang yaki secara in vitro. Tahap pendahuluan penelitian ini yaitu menguji nilai SPF (Sun Protection Factor) yang dilakukan secara invitro dengan menggunakan metode spektrofotometri UV-Vis. Serbuk kulit buah, kulit biji dan biji dimeserasi dengan pelarut etanol kemudian dipekatkan dengan rotary evaporator sehingga menghasilkan ekstrak pekat. Ekstrak etanol kulit buah, kulit biji dan biji pinang yaki memiliki nilai SPF yang berbeda yaitu 12,05 , 3,45 , dan 1,00. Dari nilai SPF ketiga sampel tersebut, kulit buah yang memiliki nilai SPF tertinggi dan termasuk dalam kategori Proteksi Maksimum sehingga kulit buah pinang yaki dapat dilakukan uji lanjut tentang aktivitas perlindungan tabir surya secara in vivo.The purpose of this study were to test the sunscreen protection activity of ethanol extract of the skin of Pinang Yaki fruit, shell skin and seed by using in vitro method. The preliminary stage of this research was to test the value of SPF (Sun Protection Factor) by invitro using UV-Vis spectrophotometry method. Skin of Pinang Yaki Fruit, shell skin and seed were maceration with ethanol then concentrated with a rotary evaporator to produce a concentrated extract. Skin of Pinang fruit, shell skin and seed have different SPF values of 12.05, 3.45, and 1.00. From the SPF values of the three samples, the skin of the fruit has the highest SPF value and is included in the Maximum Protection category so that the skin of Pinang Yaki fruit could be tested futher for  sunscreen protection activity by in vivo method.

scholarly journals A Randomized Study to Determine the Sun Protection Factor of Natural Pterostilbene from Pterocarpus Marsupium

Cosmetics ◽  
2020 ◽  
Vol 7 (1) ◽  
pp. 16 ◽  
Author(s):  
Muhammed Majeed ◽  
Shaheen Majeed ◽  
Renuka Jain ◽  
Lakshmi Mundkur ◽  
H. R. Rajalakshmi ◽  
...  
Keyword(s):  
Skin Irritation ◽  
Radical Scavenging ◽  
Sun Protection ◽  
The Sun ◽  
Protection Factor ◽  
Pterocarpus Marsupium ◽  
Sun Protection Factor ◽  
Harmful Effects

Ultraviolet (UV) rays and its harmful effects have always been a concern to skin health. Sunscreen and sunblock prevent the harmful effects of UV radiation on the skin. Sun Protection Factor (SPF) is an indication of the sun-protective capacity of an ingredient. There is an ever increasing interest in the cosmetic industry for developing novel functional ingredients from natural sources. The purpose of this study was to determine in-vitro and in vivo SPF of natural 90% pterostilbene extracted from the dried heartwood of Pterocarpus marsupium (Indian Kino). The SPF of purified pterostilbene and a formulation containing 0.4% pterostilbene was determined In Vitro using a UV spectrophotometer. Pterostilbene had an SPF of 21.73 ± 0.06, while the cream formulation had an SPF of 8.84 ± 0.01. The in vivo SPF of the 0.4% pterostilbene cream in humans was found to be 6.2 ± 1.30. Primary skin irritation tests in human subjects showed the formulation was safe and had no irritation potential. Pterostilbene was also found to have significant antioxidant activity as determined by free radical scavenging assays in vitro. These results suggest that natural pterostilbene is an antioxidant and shows SPF value both in-vitro and in the human clinical study and thus could be used as an ingredient in topical sun-protective formulations.

scholarly journals In Vitro Evaluation of Sunscreens: An Update for the Clinicians

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Maria Pelizzo ◽  
Edoardo Zattra ◽  
Piergiorgio Nicolosi ◽  
Andrea Peserico ◽  
Denis Garoli ◽  
...  
Keyword(s):  
Evaluation Method ◽  
Ethical Issues ◽  
Molecular Complexes ◽  
Protection Factor ◽  
Degree Of Protection ◽  
Potential Damage ◽  
Uv Photons ◽  
Sunscreen Products

Topical sunscreens contain molecules or molecular complexes that can absorb, reflect, or scatter UV photons. Evaluation of the efficacy of sunscreen products has been made through the Sun Protection Factor (SPF), a mean of quantitatively assessing in vivo the degree of protection offered by sunscreen products against solar radiation. In vivo evaluation of SPF has several drawbacks. First of all, this evaluation method is expensive in terms of money and time. Moreover, it raises several ethical issues concerning the potential damage to skin volunteers. Several in vitro techniques have been developed, but at present there is no broadly accepted method. In this paper, we will discuss some of the recent advances concerning the in vitro evaluation of sunscreens which would be acceptable for replacing in vivo assays.

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