scholarly journals Kinetics and cellular sources of cathelicidin during the course of experimental latent tuberculous infection and progressive pulmonary tuberculosis

2010 ◽  
Vol 161 (3) ◽  
pp. 542-550 ◽  
Author(s):  
J. Castañeda-Delgado ◽  
R. Hernández-Pando ◽  
C. J. Serrano ◽  
D. Aguilar-León ◽  
J. León-Contreras ◽  
...  
Keyword(s):  
Pulmonary Tuberculosis ◽  
Tuberculous Infection

scholarly journals Increased Synthesis of Anti-Tuberculous Glycolipid Immunoglobulin G (IgG) and IgA with Cavity Formation in Patients with Pulmonary Tuberculosis

2008 ◽  
Vol 15 (3) ◽  
pp. 544-548 ◽  
Author(s):  
Masako Mizusawa ◽  
Mizuoho Kawamura ◽  
Mikio Takamori ◽  
Tetsuya Kashiyama ◽  
Akira Fujita ◽  
...  
Keyword(s):  
Pulmonary Tuberculosis ◽  
Immunoglobulin G ◽  
White Blood Cells ◽  
Cd40 Ligand ◽  
Carbohydrate Antigen ◽  
Tuberculous Infection ◽  
X Rays ◽  
Soluble Cd40 Ligand ◽  
Active Pulmonary Tuberculosis ◽  
Positive Correlations

ABSTRACT Tuberculous glycolipid (TBGL) antigen is a cell wall component of Mycobacterium tuberculosis and has been used for the serodiagnosis of tuberculosis. We investigated correlations between the levels of anti-TBGL antibodies and a variety of laboratory markers that are potentially influenced by tuberculous infection. Comparisons between patients with cavitary lesions and those without cavitary lesions were also made in order to determine the mechanism underlying the immune response to TBGL. Blood samples were obtained from 91 patients with both clinically and microbiologically confirmed active pulmonary tuberculosis (60 male and 31 female; mean age, 59 ± 22 years old). Fifty-nine patients had cavitary lesions on chest X-rays. Positive correlations were found between anti-TBGL immunoglobulin G (IgG) and C-reactive protein (CRP) (r = 0.361; P < 0.001), between anti-TBGL IgA and soluble CD40 ligand (sCD40L) (r = 0.404; P < 0.005), between anti-TBGL IgG and anti-TBGL IgA (r = 0.551; P < 0.0000005), and between anti-TBGL IgM and serum IgM (r = 0.603; P < 0.00000005). The patients with cavitary lesions showed significantly higher levels of anti-TBGL IgG (P < 0.005), anti-TBGL IgA (P < 0.05), white blood cells (P < 0.01), neutrophils (P < 0.005), basophils (P < 0.0005), natural killer cells (P < 0.05), CRP (P < 0.0005), KL-6 (sialylated carbohydrate antigen KL-6) (P < 0.0005), IgA (P < 0.05), and sCD40L (P < 0.01). The observed positive correlations between the anti-TBGL antibody levels and inflammatory markers indicate the involvement of inflammatory cytokines and NKT cells in the immunopathogenesis of pulmonary tuberculosis.

Tuberculosis Pulmonar Infantil

PEDIATRICS ◽  
1959 ◽  
Vol 23 (1) ◽  
pp. 165-165
Author(s):  
MARGARET H. D. SMITH
Keyword(s):  
Pulmonary Tuberculosis ◽  
Children And Adolescents ◽  
Primary Infection ◽  
Tuberculous Infection ◽  
Primary Complex ◽  
Hematogenous Dissemination ◽  
Segmental Anatomy ◽  
Congenital Tuberculosis ◽  
Endobronchial Tuberculosis

This profusely and very beautifully illustrated textbook should be a welcome addition to the libraries of our Spanish-reading colleagues. Particularly good chapters on segmental anatomy of the lungs and on roentgenographic findings in the chest in tuberculous children are followed by chapters on the evolution of the primary complex; on endobronchial tuberculosis and obstructive lesions; pleurisy and pericarditis; progressive primary lesions with cavitation; hematogenous dissemination; chronic pulmonary tuberculosis of "reinfection" type in children and adolescents. Shorter chapters are devoted to such special problems as primary infection during puberty, primary infection in adults, congenital tuberculosis and the chronology of tuberculous infection in children.

scholarly journals THE FOCAL PULMONARY TUBERCULOSIS OF CHILDREN AND ADULTS

1917 ◽  
Vol 25 (6) ◽  
pp. 855-876 ◽  
Author(s):  
Eugene L. Opie
Keyword(s):  
Pulmonary Tuberculosis ◽  
Infected Animal ◽  
Adult Life ◽  
Tuberculous Infection ◽  
Human Beings ◽  
Pulmonary Lesions ◽  
Usual Type ◽  
Almost All

Evidence of tuberculous infection has been found in the lungs of all of fifty adults who have been examined. Approximately one-half of all adults have encapsulated lesions of the lungs or bronchial lymphatic nodes, whereas in one-third pulmonary and lymphatic lesions are firmly calcified and completely healed. Tuberculous pulmonary lesions of adults who have died of diseases other than tuberculosis are of two types: (1) apical tuberculosis similar to the usual type of fatal phthisis and unaccompanied by caseation, of the regional lymphatic nodes; (2) focal tuberculosis not more commonly situated in the apices of the lungs than elsewhere and accompanied by caseation (or calcification) of the adjacent lymphatic nodes. Focal pulmonary tuberculosis of adults is identical with the tuberculosis of childhood. It occurs in at least 92 per cent of all adults. It may be acquired between the ages of 2 and 10 years but in more than half of all individuals (in this city) makes its appearance between the ages of 10 and 18 years. Tuberculosis of children does not select the apices of the lungs, is accompanied by massive tuberculosis of regional lymphatic nodes, and exhibits the characters of tuberculosis in a freshly infected animal, whereas tuberculosis which occurs in the pulmonary apices of adults has the characters of a second infection. Almost all human beings are spontaneously "vaccinated" with tuberculosis before they reach adult life.

scholarly journals TUBERCULOUS PATIENTS

2016 ◽  
Vol 23 (01) ◽  
pp. 045-049
Author(s):  
Abid Naeem
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Pulmonary Tuberculosis ◽  
Complete Blood Count ◽  
Economic Status ◽  
Fasting Blood Glucose ◽  
Tuberculous Infection ◽  
Family History Of Diabetes ◽  
Multiple Systems ◽  
Pulmonary Tb

The objective of present study was to screen out the diabetes mellitus by fastingblood glucose (FBG) in patients with pulmonary tuberculosis. Background: Diabetes mellitusand Tuberculosis has strong co-relation and complicates each other. Diabetes increases therisk of infections including tuberculosis particularly pulmonary TB, Therefore making antituberculousdrugs ineffective. Similarly M. tuberculous infection predisposes to diabetesmellitus and complicates it further. Patients simultaneously having, both diabetes mellitus andtuberculosis, the chances of multiple systems involvement becomes high. The delayed orineffective response to anti tuberculous chemotherapy raises suspicion of underlying diabetesmellitus .There for such patients should be screen out by fasting blood glucose (FBG) levels soas to treat the treat the diabetes as well. Objectives: The objective of this study was to screenout diabetes in pulmonary TB patients by fasting blood glucose level (FBG) especially wherethe treatment response of anti-tuberculous drug is delayed or poor. Study Design: This wasprospective observational study. Place and Duration of Study: This study was conductedat DHQ-teaching hospital Mirpur Azad Kashmir from February 2013 to December 2014 .Thisincluded both in and outdoor patients. Inclusion criteria: 1. Age range of tuberculous patientsbetween 20-40 years. 2. Pulmonary tuberculous patients. Exclusion criteria: 1. PulmonaryTB patients with co-existent diabetes mellitus. 2. TB patients with renal failure, autoimmunediseases like rheumatoid arthritis, SLE, immunosuppressant drugs and steroid were excluded.Material and Methods: Ninety-five diagnosed patients of pulmonary TB were selected. Thequestionnaire form was designed according to objective of study. This Included with patientshaving pulmonary TB with but still not screened out for diabetes .The questionnaire containedhistory, general physical and systemic examination, especially respiratory system. Risk factorslike family history of diabetes and TB were evaluated. The socio–economic status of patients wascarefully assessed. Routine investigations like complete blood count, ESR, fasting and randomblood glucose were done. Three morning sputum specimens and fasting blood glucose (FBG)were main tools of diagnosis of TB. The data thus obtained, was subjected to SPSS verssion-20for statistical analysis. Results: A total of 95 patients with pulmonary tuberculosis were selectedincluding in and outdoor patients. Out of them, 65 patients were males, and 30 were females.Age group mainly ranging between 20-40 of years. Screening of diabetes in 95 tuberculouspatients was done by fasting blood glucose. Seventeen patients (17), twelve (12) male and five(05) female were screened out to be diabetic. Conclusion: Screening by fasting blood glucoseis an effective tool in diagnosis of diabetes mellitus in tuberculous patients.

scholarly journals A case report of gingival tuberculosis: an Otolaryngologist’s perspective

2020 ◽  
Vol 12 (5) ◽  
pp. 172-174
Author(s):  
Apoorva Kumar Pandey ◽  
Tripti Maithani ◽  
Aparna Bhardwaj
Keyword(s):  
Case Report ◽  
Early Diagnosis ◽  
Pulmonary Tuberculosis ◽  
Oral Cavity ◽  
Clinical Condition ◽  
Tuberculous Infection ◽  
Atypical Presentation ◽  
Rare Clinical Entity ◽  
Prompt Treatment ◽  
Primary Finding

Tuberculous infection of the oral cavity is an exceedingly rare clinical entity and it generally occurs secondary to pulmonary tuberculosis, with the gingival involvement as its only primary finding. Due to its rarity and atypical presentation this condition often gets misdiagnosed. We report here a case of secondary oral tuberculosis in a 44 year old male patient who presented with gingival involvement. The diagnosis was based on sputum examination, radiology of chest, montaux test and histopathology. Early diagnosis and prompt treatment is important for management of this clinical condition.

Sign in / Sign up

Export Citation Format

Share Document