Serum Insulin Level Versus Blood Pressure: A Cross-sectional, Case-controlled Study in Non-obese, Middleaged Japanese Subjects with Normal Glucose Tolerance

1994 ◽  
Vol 11 (1) ◽  
pp. 42-49 ◽  
Author(s):  
T. Baba ◽  
T. Kodama ◽  
T. Tomiyama ◽  
D-R Sohn ◽  
T. Ishizaki
Keyword(s):  
Blood Pressure ◽  
Serum Insulin ◽  
Insulin Level ◽  
Normal Glucose Tolerance ◽  
Controlled Study ◽  
Serum Insulin Level ◽  
Cross Sectional ◽  
Normal Glucose ◽  
Level Versus ◽  
Japanese Subjects

scholarly journals Fasting Insulin in Essential Hypertension

2015 ◽  
Vol 9 (2) ◽  
pp. 54-58
Author(s):  
Susmita Sinha ◽  
Qazi Shamima Akhter ◽  
Qazi Farzana Akhter ◽  
Masuma Tasnim ◽  
Farhana Rahman
Keyword(s):  
Essential Hypertension ◽  
Serum Insulin ◽  
Fasting Blood Glucose ◽  
Insulin Level ◽  
Cross Sectional Study ◽  
Serum Insulin Level ◽  
Fasting Serum ◽  
College Hospital ◽  
Cross Sectional ◽  
Medical College

Background: An association between essential hypertension and defective insulin secretion has been identified. Objective: To estimate fasting serum insulin level in adult male with essential hypertension to observe its relationship to hypertension. Methods: This cross sectional study was conducted in the Department of Physiology, Dhaka Medical College, Dhaka from July 2012 to June 2013. A total number of one hundred fifty male subjects were selected with age ranging from 25 to 45 years. Seventy five male essential hypertensive were enrolled from Out- patient Department of Medicine, Dhaka Medical College Hospital, Dhaka. Age matched seventy five apparently healthy males were studied as control. Fasting serum insulin level was measured by ELISA method and fasting blood glucose by glucose oxidase method. For statistical analyses, unpaired Student’s ‘t’ and Pearson’s correlation coefficient (r) tests were performed. Results: Fasting serum insulin level was significantly (P<0.001) higher in essential hypertensive male patients than normotensive subjects. Fasting serum insulin level shows significant positive correlation with systolic blood pressure in hypertensive patients. Conclusion: This study reveals that essential hypertension has positive and significant relationship with fasting serum insulin level. DOI: http://dx.doi.org/10.3329/jbsp.v9i2.22797 Bangladesh Soc Physiol. 2014, December; 9(2): 54-58

scholarly journals Insulin Secretory Status in Obese Female

2015 ◽  
Vol 9 (2) ◽  
pp. 72-77
Author(s):  
Masuma Tasnim ◽  
Qazi Shamima Akhter ◽  
Salma Akhter ◽  
Nasreen Sultana Lovely ◽  
Khadiza Begum ◽  
...  
Keyword(s):  
Cell Function ◽  
Serum Insulin ◽  
Pancreatic Beta Cell ◽  
Insulin Level ◽  
Personal Contact ◽  
Serum Insulin Level ◽  
Fasting Serum ◽  
Cross Sectional ◽  
Obese Female ◽  
Female Subjects

Background: In obesity insulin hypersecretion is a key feature indicating the abnormal pancreatic beta cell function which is the fundamental defect in the development of NIDDM, hypertension and cardiovascular diseases. Objective: To assess the secretory status of insulin in adult obese female. Methods: The present study was a cross sectional analytical study and conducted in the Department of Physiology, Dhaka Medical College, Dhaka from July 2012 to June 2013. 50 obese female subjects of 20-40 years were included from Out-patient Department (Obesity clinic) of BIRDEM Hospital, Dhaka and by personal contact from different areas of Dhaka city. 50 age matched, healthy non-obese female subjects selected as controls . Fasting serum insulin level was measured by ELISA and fasting glucose level was measured by Glucose oxidase method. The insulin secretory status was calculated by HOMA-%B using HOMA software. For statistical analysis unpaired Student’s ‘t’ test and Pearson’s correlation coefficient (r) test were performed as applicable . Result: Mean fasting serum insulin and HOMA%B (P<0.001) were higher in the obese than that non obese. Fasting serum insulin level and HOMA%B showed significantly positive correlation with WHR. Conclusion: This study concludes that obese individual develops a state of insulin hypersecretion and hyperinsulinemia. DOI: http://dx.doi.org/10.3329/jbsp.v9i2.22800 Bangladesh Soc Physiol. 2014, December; 9(2): 72-77

Weight fluctuations could increase blood pressure in android obese women

1999 ◽  
Vol 96 (6) ◽  
pp. 677-680 ◽  
Author(s):  
M. T. GUAGNANO ◽  
V. PACE-PALITTI ◽  
C. CARRABS ◽  
D. MERLITTI ◽  
S. SENSI
Keyword(s):  
Blood Pressure ◽  
Normal Glucose Tolerance ◽  
Multiple Regression Model ◽  
Weight Cycling ◽  
Obese Women ◽  
Cross Sectional ◽  
Central Type ◽  
Weight Losses ◽  
Normal Glucose ◽  
History Of

Recent studies have documented a relationship between increased morbidity and mortality from cardiovascular diseases and a history of weight cycling (WC) in obese subjects. We performed a cross-sectional analysis in 96 weight-cycling android obese women, matched with 96 non-weight-cycling android obese women by age, body mass index (BMI) and waist-to-hip ratio (WHR), to evaluate any increase in blood pressure (BP) levels in association with WC. The patients were all between 20 and 45 years old, were non-menopausal, did not smoke, did not take any medication, had normal glucose tolerance and were otherwise healthy. A history of WC was established on the basis of at least five weight losses in the previous 5 years due to dieting, with a weight loss of at least 4.5 kg per cycle. We documented higher levels of casual BP in the weight-cycling obese compared with the non-weight-cycling subjects: 147±12/90±8 mmHg versus 125±14/79±8 mmHg (P < 0.001). The women with WC showed a statistically significant positive correlation between BP and age, weight, BMI, waist circumference, WHR, total weight regained and weight cycling index (WCI). However, in a multiple regression model only the WHR and WCI contributed significantly to the BP variability. These findings could support the hypothesis that it is the combined exposure of central-type obesity and WC that strongly raises the prediction of hypertension.

scholarly journals Association of Hypertension with Type 2 Diabetes Mellitus in Adult female

2018 ◽  
Vol 29 (1) ◽  
pp. 7-12
Author(s):  
Nahid Yeasmin ◽  
Sayeeda Mahmuda ◽  
Shamima Akther ◽  
Sharmin Nahar ◽  
Zakia Sultana ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Blood Pressure ◽  
Blood Glucose ◽  
Diastolic Blood Pressure ◽  
Serum Insulin ◽  
Fasting Blood Glucose ◽  
Insulin Level ◽  
Serum Insulin Level ◽  
Fasting Serum ◽  
Medical College

Background: Diabetes mellitus is one of the most widespread endocrine disorder in female and its complications are increasing all over the world, leading to life threatening medical problems like cardiovascular diseases, stroke and end stage renal diseases. An association between hypertension and diabetes mellitus has been identified.Objectives: The study was carried out to observe the association of hypertension with diabetes mellitus in adult female subjects.Methods : This cross sectional study was conducted in the Department of Physiology, Dhaka Medical College, Dhaka, during the period of January 2011 to December 2011. A total number of one hundred female subjects were selected with age ranging from30 to50 years. Among them 50 diabetic female subjects were included from out-patient department of Endocrinology, Dhaka Medical College Hospital, Dhaka as study group(B) and 50 apparently healthy female were taken as control group(A) for comparison. Fasting serum insulin level was measured by ELISA method in the Department of Laboratory of National Institute of ENT, Dhaka and fasting blood glucose was estimated by glucose oxidase method in Department of Dhaka Medical College in both groups. Systolic blood pressure and diastolic blood pressure of all participants were recorded by standard method. Data was analyzed by Unpaired Student’s- test and Pearson’s correlation co-efficient (r) test as applicable.Results: The value of fasting serum insulin level was significantly higher in diabetic subjects than those of non-diabetic subjects. Fasting blood glucose level was significantly higher diabetic patient in comparison to those of non-diabetic subjects. In diabetic subjects fasting serum insulin and fasting blood glucose levels were higher and showed positive correlation with systolic and diastolic blood pressure.Conclusion: Present study revealed that systolic and diastolic blood pressure has positive relationship with fasting serum insulin and fasting blood glucose levels.Bangladesh J Medicine Jan 2018; 29(1) : 7-12

scholarly journals Mediterranean Diet and Healthy Eating in Subjects with Prediabetes from the Mollerussa Prospective Observational Cohort Study

Nutrients ◽  
2021 ◽  
Vol 13 (1) ◽  
pp. 252
Author(s):  
Mireia Falguera ◽  
Esmeralda Castelblanco ◽  
Marina Idalia Rojo-López ◽  
Maria Belén Vilanova ◽  
Jordi Real ◽  
...  
Keyword(s):  
Glucose Tolerance ◽  
Mediterranean Diet ◽  
Healthy Eating ◽  
Dietary Patterns ◽  
Normal Glucose Tolerance ◽  
Healthy Eating Index ◽  
Study Cohort ◽  
Cross Sectional ◽  
Normal Glucose ◽  
Multivariable Analyses

We aimed to assess differences in dietary patterns (i.e., Mediterranean diet and healthy eating indexes) between participants with prediabetes and those with normal glucose tolerance. Secondarily, we analyzed factors related to prediabetes and dietary patterns. This was a cross-sectional study design. From a sample of 594 participants recruited in the Mollerussa study cohort, a total of 535 participants (216 with prediabetes and 319 with normal glucose tolerance) were included. The alternate Mediterranean Diet score (aMED) and the alternate Healthy Eating Index (aHEI) were calculated. Bivariable and multivariable analyses were performed. There was no difference in the mean aMED and aHEI scores between groups (3.2 (1.8) in the normoglycemic group and 3.4 (1.8) in the prediabetes group, p = 0.164 for the aMED and 38.6 (7.3) in the normoglycemic group and 38.7 (6.7) in the prediabetes group, p = 0.877 for the aHEI, respectively). Nevertheless, women had a higher mean of aMED and aHEI scores in the prediabetes group (3.7 (1.9), p = 0.001 and 40.5 (6.9), p < 0.001, respectively); moreover, they had a higher mean of aHEI in the group with normoglycemia (39.8 (6.6); p = 0.001). No differences were observed in daily food intake between both study groups; consistent with this finding, we did not find major differences in nutrient intake between groups. In the multivariable analyses, the aMED and aHEI were not associated with prediabetes (odds ratio (OR): 1.19, 95% confidence interval (CI): 0.75–1.87; p = 0.460 and OR: 1.32, 95% CI: 0.83–2.10; p = 0.246, respectively); however, age (OR: 1.04, 95% CI: 1.02–1.05; p < 0.001), dyslipidemia (OR: 2.02, 95% CI: 1.27–3.22; p = 0.003) and body mass index (BMI) (OR: 1.09, 95% CI: 1.05–1.14; p < 0.001) were positively associated with prediabetes. Physical activity was associated with a lower frequency of prediabetes (OR: 0.48, 95% CI: 0.31–0.72; p = 0.001). In conclusion, subjects with prediabetes did not show a different dietary pattern compared with a normal glucose tolerance group. However, further research is needed on this issue.

Sign in / Sign up

Export Citation Format

Share Document