Geographically situated in the juxtaposition of East and West, peace among nations is the zeal of Iranian people. As a founding member of both the League of Nations and the United Nations, Iran was seen as a great supporter of multilateralism. Iran voted in favor of the Universal Declaration of Human Rights in 1948 and hosted the first UN Human Rights Conference in its capital in 1968. Following the 1979 Islamic Revolution and the crisis of the US diplomatic and consular staff in Tehran, the United States put in place embargoes against the newly elected Iranian government and instituted proceedings against Iran before the International Court of Justice (ICJ). Iran did not participate in the proceedings to defend itself and the court ruled that Iran has violated its international obligations. Since then, Iran has faced many challenges in its international relations especially with the Western powers. For example, neither Iraq’s aggression against Iran nor the use of chemical weapons against Iranian civilians was recognized by the UN Security Council; different types of unilateral, regional, and international sanctions have been imposed on Iran; and the human rights situation in Iran has been repeatedly criticized by individual Western states and the UN mechanisms. Furthermore, Iran’s nuclear program was considered by the Security Council under Chapter VII of the UN Charter, while the US officials have emphasized that military options against Iran remain “on the table.” Iranian academics and international lawyers have extensively discussed the last four decades of Iran’s presence on the international plane as a thought-provoking issue in the fields of international responsibility, diplomatic and consular law, state immunity, arbitration, judicial adjudication, human rights, humanitarian law, use of force, law of the sea, fight against terrorism, and nonproliferation, just to name a few. This long list, however, has created its own negative impact internally: doubts about the effectiveness and efficacy of relevant rules of international law which found more basis after the United States announced its withdrawal from the Iran nuclear deal and reimposed some further tough sanctions against Iran. Seeking to use international law as a tool to protect its national interests, the Iranian government has brought this case to the ICJ and is still making efforts to preserve the nuclear deal. This contribution introduces the different Iranian resources and institutions in the field and also deals with some of the above-mentioned topics as the most important subjects for Iran in the context of international law.