scholarly journals Association of reading problems with speech and motor development: results from a British 1946 birth cohort

2010 ◽  
Vol 52 (7) ◽  
pp. 680-681 ◽  
Author(s):  
Darya Gaysina ◽  
Barbara Maughan ◽  
Marcus Richards
BMJ Open ◽  
2019 ◽  
Vol 9 (5) ◽  
pp. e025755 ◽  
Author(s):  
Diana Kuh ◽  
Rebecca Hardy ◽  
Joanna M Blodgett ◽  
Rachel Cooper

ObjectivesTo test whether developmental factors are associated with grip strength trajectories between 53 and 69 years, and operate independently or on the same pathway/s as adult factors.DesignBritish birth cohort study.SettingEngland, Scotland and Wales.Participants3058 men and women.Main outcome measuresGrip strength (kg) at ages 53, 60–64 and 69 were analysed using multilevel models to estimate associations with developmental factors (birth weight, growth parameters, motor and cognitive development) and father’s social class, and investigate adult factors that could explain observed associations, testing for age and sex interactions.ResultsIn men, heavier birth weight, beginning to walk ‘on time’, later puberty and greater weight 0–26 years and in women, heavier birth weight and earlier age at first standing were independently associated with stronger grip but not with its decline. The slower decline in grip strength (by 0.07 kg/year, 95% CI 0.02 to 0.11 per 1 SD, p=0.003) in men of higher cognitive ability was attenuated by adjusting for adult verbal memory.ConclusionsPatterns of growth and motor development have persisting associations with grip strength between midlife and old age. The strengthening associations with cognition suggest that, at older ages, grip strength increasingly reflects neural ageing processes. Interventions across life that promote muscle development or maintain muscle strength should increase the chance of an independent old age.


2018 ◽  
Vol 2 (S1) ◽  
pp. 86-86
Author(s):  
William H. Coe ◽  
Jason Feinberg ◽  
Robert Grunier ◽  
Brenda Eskenazi ◽  
Heather Volk

OBJECTIVES/SPECIFIC AIMS: Previous studies suggest that prenatal exposure to environmental pollutants can have an adverse effect on brain development. We examine the association between prenatal near roadway air pollution (NRAP) exposure and early neurodevelopment. METHODS/STUDY POPULATION: The Center for the Health Assessment of Mothers and Children of Salinas (CHAMACOS) Study is a prospective birth cohort that began in 1999 with 605 mother-child pairs of primarily Mexican-American descent. Maternal residence during pregnancy was geocoded using ArcGIS and prenatal NRAP exposure was assigned using the CALINE4 line source dispersion model. We used composite Bayley Scale scores for cognitive and motor development, and created separate linear regression models at 6, 12, and 24 months of age. RESULTS/ANTICIPATED RESULTS: After adjusting for relevant maternal and child characteristics, preliminary estimates suggest that prenatal NRAP exposure is associated with a nonsignificant increase in Bayley Scale scores at 6 and 24 months (cognitive: β=0.13, p-value=0.20 and motor: β=0.08, p-value=0.58 at 6 months; cognitive: β=0.16, p-value=0.42 and motor: β=0.20, p-value=0.25 at 24 months) and a nonsignificant decrease at 12 months (cognitive: β=−0.07, p-value=0.64 and motor: β=−0.12, p-value=0.56). DISCUSSION/SIGNIFICANCE OF IMPACT: Our preliminary findings do not suggest that prenatal NRAP exposure is associated with early cognitive development. Additional exploration of co-exposures known to effect neurodevelopment should be examined in this rural population.


PEDIATRICS ◽  
1987 ◽  
Vol 79 (4) ◽  
pp. 529-537
Author(s):  
Paula Piekkala ◽  
Pentti Kero ◽  
Matti Sillanpää ◽  
Risto Erkkola

In a regional birth cohort of 5,356 live-born infants, during 12 consecutive months, 46 (0.9%) infants suffered from respiratory distress syndrome. Ten of them died before the age of 2 years. The cause of death was respiratory distress syndrome in two cases, intracerebral hemorrhage in four cases, asphyxia in one case, and congenital erythropoetic anemia in one case. Of the 36 survivors, 34 could be traced for the follow-up. Growth and development of the survivors with respiratory distress syndrome were compared with that of 3,375 term infants in the birth cohort with birth weights at the tenth percentile or above with no risk factors recognized during pregnancy, labor, delivery, or the neonatal period. Normal development was found in 85% of the survivors with respiratory distress syndrome and 99% of the control infants at the age of 2 years. Intracerebral hemorrhage and low one- and five-minute Apgar scores were associated with unfavorable outcome at 2 years in the survivors with respiratory distress syndrome. The developmental scores were significantly poorer than those of the controls at 2 years for gross motor, audiovisual, and psychosocial categories, whereas for fine motor development, the difference disappeared by the 2 years of age. The growth of the survivors with respiratory distress syndrome was satisfactory even if their heights remained below that of their control peers.


BMJ Open ◽  
2019 ◽  
Vol 9 (1) ◽  
pp. e024440 ◽  
Author(s):  
Azza Shoaibi ◽  
Brian Neelon ◽  
Truls Østbye ◽  
Sara E Benjamin-Neelon

ObjectivesTo investigate longitudinal associations between gross motor development, motor milestone achievement and weight-for-length z scores in a sample of infants. In a secondary aim, we explored potential bidirectional relationships, as higher weight-for-length z scores may impede motor development, and poor motor development may lead to obesity.DesignThe design was an observational birth cohort.SettingWe used data from the Nurture study, a birth cohort of predominately black women and their infants residing in the Southeastern USA.Participants666 women enrolled their infants in Nurture. We excluded infants with missing data on exposure, outcome or main covariates, leaving a total analytic sample of 425 infants.Primary outcomeThe outcome was weight-for-length z score, measured when infants were 3, 6, 9 12 months.ResultsAmong infants, 64.7% were black, 18.8% were white and 16.9% were other/multiple race. Mean (SD) breastfeeding duration was 17.6 (19.7) weeks. Just over one-third (38.5%) had an annual household income of < $20 000. After adjusting for potential confounders, higher motor development score was associated with lower weight-for-length z score (−0.004; 95% CI −0.001 to –0.007; p=0.01), mainly driven by associations among boys (−0.007; 95% CI −0.014 to –0.001; p=0.03) and not girls (0.001; 95% CI −0.005 to 0.008; p=0.62). Earlier crawling was the only milestone associated with a lower weight-for-length z score at 12 months (−0.328; 95% CI −0.585 to 0.072; p=0.012). However, this association appeared to be driven by male infants only (−0.461; 95% CI −0.825 to −0.096; p=0.01). Weight-for-length z score was unrelated to subsequent motor development score and was thus not bidirectional in our sample.ConclusionsHigher motor development score and earlier crawling were associated with lower subsequent weight-for-length z score. However, this was primary true for male infants only. These findings contribute to the growing body of evidence suggesting that delayed motor development may be associated with later obesity.


2006 ◽  
Vol 47 (1) ◽  
pp. 25-29 ◽  
Author(s):  
G.K. Murray ◽  
J. Veijola ◽  
K. Moilanen ◽  
J. Miettunen ◽  
D.C. Glahn ◽  
...  

PLoS ONE ◽  
2009 ◽  
Vol 4 (8) ◽  
pp. e6837 ◽  
Author(s):  
Charlotte L. Ridgway ◽  
Ken K. Ong ◽  
Tuija H. Tammelin ◽  
Stephen Sharp ◽  
Ulf Ekelund ◽  
...  

2020 ◽  
Author(s):  
Otávio Amaral de Andrade Leão ◽  
Mariângela Freitas da Silveira ◽  
Marlos Rodrigues Domingues ◽  
Joseph Murray ◽  
Nelson Arns Neumann ◽  
...  

Abstract Background: The first years of life are the most important for human development, which is influenced by diverse factors, such as childcare attendance. Yet, little is known about the longitudinal influence of childcare in diverse domains of development. The aim of the present study was to assess the development and to measure potential influences of childcare attendance in two-year-olds from the 2015 Pelotas (Brazil) Birth Cohort Study. Methods: The present study used longitudinal data from the 2015 Pelotas Birth Cohort. Childhood development at two-year-olds was assessed throughout INTER-NDA (INTERGROWTH-21st Neurodevelopment Assessment). Childcare attendance was measured at ages 1 and 2 years old and categorized as: a) never went to childcare; b) attended some childcare (either at 12 or 24 months); c) always attended childcare (both 12 and 24 months). Demographic, socioeconomic, health, and child stimulation variables were considered as confounders. Crude and adjusted analysis of childcare attendance and early childhood development were performed using linear regression. Results: Among the 3,870 infants included in the analyses, around 2/3 never went to childcare. In the crude analyses, any exposure to childcare was positively associated with development, except for in the motor domain. It was also perceived a trend positive association and higher mean values for the always category. In the adjusted analyses only children who always went to childcare had higher development scores in the total (β: 0.17, 95% CI: 0.06; 0.28), cognitive (β: 0.10, 95% CI:-0.003; 0.21) and language (β:0.10, 95% CI:-0.003; 0.21) domains, even after adjustment for stimulation variables. Conclusions: This study suggests that childcare may help improve early childhood development. The association was particularly strong for the total global development domain, even after adjusting for stimulation, but there was no association with motor development. Considering the low prevalence of children in childcare, and that it may support child development it is recommended to improve childcare opportunities in early childhood.


Sign in / Sign up

Export Citation Format

Share Document