Predictive Value of High-Sensitivity C-Reactive Protein in Patients with Idiopathic Dilated Cardiomyopathy

2005 ◽  
Vol 28 (s1) ◽  
pp. S233-S236 ◽  
Author(s):  
STEFFEN LAMPARTER ◽  
WOLFRAM GRIMM
Keyword(s):  
Dilated Cardiomyopathy ◽  
Predictive Value ◽  
High Sensitivity ◽  
Idiopathic Dilated Cardiomyopathy ◽  
C Reactive Protein ◽  
Reactive Protein

Coenzyme Q10 and high-sensitivity C-reactive protein in ischemic and idiopathic dilated cardiomyopathy

2008 ◽  
Vol 46 (3) ◽  
Author(s):  
Mehmet Şeneş ◽  
Ali Rıza Erbay ◽  
F. Meriç Yılmaz ◽  
B. Çiğdem Topkaya ◽  
Oğuzhan Zengi ◽  
...  
Keyword(s):  
Dilated Cardiomyopathy ◽  
Coenzyme Q10 ◽  
High Sensitivity ◽  
Idiopathic Dilated Cardiomyopathy ◽  
C Reactive Protein ◽  
Reactive Protein

scholarly journals VALIDITY OF C- REACTIVE PROTEIN IN DIAGNOSIS OF NEONATAL SEPSIS.

2020 ◽  
pp. 1-4
Author(s):  
Ghongade P. G. ◽  
Khaire P. B.
Keyword(s):  
Birth Weight ◽  
Neonatal Sepsis ◽  
Predictive Value ◽  
Screening Test ◽  
Treatment Strategies ◽  
High Sensitivity ◽  
C Reactive Protein ◽  
Suspected Sepsis ◽  
Adequate Treatment ◽  
Reactive Protein

Background: Neonatal sepsis with its high incidence &grave prognosis, in spite of adequate treatment with modern antibiotics, has been a challenge for all times. Optimal diagnosis and treatment strategies are difficult to define. It is essential to diagnose early with laboratory investigation like serial CRP; so that a feasible, rapid and a relatively economic method to diagnose neonatal sepsis at earliest can be instituted even at basic health care level. hence a study was planned to find out the role of CRP against blood culture in early detection of neonatal sepsis. Aim & Objective: To evaluate Validity of C-Reactive Protein as a screening test in neonatal sepsis. Material and Method: This prospective study was carried out inpaediatric dept of medical college. 100 neonates (≤ 28 days) with suspected neonatal sepsis having a birth weight of ≥ 1000 grams admitted during a period from January 2020 to March 2020 were screened primarily with C-Reactive Protein. Serial level of CRPon the day of admission,2nd ,4th ,6th ,8th& 10th day was compared with the serial blood cultureon the day of admission,8th,15th& 21st day to establish the validity of CRP as a screening test.Data analysis carried out by Percentages, Chi Square test, Sensitivity, Specificity, Positive predictive value, Negative predictive value. Results: Amongst 100neonate 76% were early neonates,65% were low birth weight,CRP was having high sensitivity & specificity(78.57%,76.74% respectively). ROC analysis showed AUC 0.8 with p<0.001.Conclusion: CRP is a good screening test & establishes its validity in diagnosing suspected sepsis.

C-Reactive Protein and Aortic Stiffness in Patients with Idiopathic Dilated Cardiomyopathy

2007 ◽  
Vol 24 (1) ◽  
Author(s):  
Feridun Kosar ◽  
Yüksel Aksoy ◽  
Gulacan Ozguntekin ◽  
Ertan Yetkin ◽  
Hakan Gunen
Keyword(s):  
Dilated Cardiomyopathy ◽  
Aortic Stiffness ◽  
Idiopathic Dilated Cardiomyopathy ◽  
C Reactive Protein ◽  
Reactive Protein

scholarly journals High Sensitivity C-Reactive Protein Predictive Value for Cardiovascular Disease: A Nested Case Control from Isfahan Cohort Study (ICS)

Global Heart ◽  
2020 ◽  
Vol 15 (1) ◽  
pp. 3 ◽  
Author(s):  
Pooya Koosha ◽  
Hamidreza Roohafza ◽  
Nizal Sarrafzadegan ◽  
Mehrbod Vakhshoori ◽  
Mohammad Talaei ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Cohort Study ◽  
Predictive Value ◽  
High Sensitivity ◽  
Case Control ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Nested Case Control

Anaemia is a predictor of early death or cardiac transplantation in children with idiopathic dilated cardiomyopathy

2011 ◽  
Vol 22 (3) ◽  
pp. 293-300 ◽  
Author(s):  
Issam Kammache ◽  
Giovanni Parrinello ◽  
Davide Marini ◽  
Damien Bonnet ◽  
Gabriella Agnoletti
Keyword(s):  
Confidence Interval ◽  
Dilated Cardiomyopathy ◽  
Cardiac Transplantation ◽  
Cox Model ◽  
Early Death ◽  
Hazard Ratio ◽  
Idiopathic Dilated Cardiomyopathy ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
First Diagnosis

AbstractIntroductionThe aim of our study was to establish the prevalence and the prognostic value of haematological abnormalities in children with cardiac failure.Patients and methodsA series of 218 consecutive children with a first diagnosis of idiopathic dilated cardiomyopathy were retrospectively examined. Haematological evaluation was performed at first diagnosis. Death or cardiac transplantation was the main outcome measure.ResultsThe median age was 0.6 years, ranging from 1 day to 15.8 years and median follow-up was 2.65 years, ranging from 0 to 17.2 years. After a median interval of 0.2 years, ranging from 0 to 8.7 years, 56 patients died and 25 were transplanted. Event-free survival at 1 and 5 years was 68% (95% confidence interval, 63–75%) and 62% (95% confidence interval, 56–69%). Blood levels of haemoglobin less than 10 grams per decilitre, urea over 8 millimoles per litre, and C-reactive protein over 10 milligrams per litre were found in 24%, 20%, and 24% of patients, respectively. The log-rank test showed that haemoglobin (p = 0.000) and C-reactive protein (p = 0.021) were predictors of death or transplantation. In the multivariate Cox model, haemoglobin (hazard ratio = 0.735; confidence interval = 0.636–0.849; p = 0.000) and urea (hazard ratio = 1.083; confidence interval = 1:002–1:171; p = 0.045) were predictive of poor outcome. Cubic spline functions showed that the positive role of haemoglobin on survival was linear for values less than 12 grams per decilitre and null for values more than 12 grams per decilitre. Adaptive index models for risk stratification and Classification and Regression Tree analysis allowed to identify the cut-off values for haemoglobin (less than 10.2 grams per decilitre) and urea (more than 8.8 millimoles per litre), as well as to derive a predictor model.ConclusionsIn children with idiopathic dilated cardiomyopathy, anaemia is the strongest independent prognostic factor of early death or transplantation.

scholarly journals C-Reactive Protein and Atrial Fibrillation in Idiopathic Dilated Cardiomyopathy

2009 ◽  
Vol 32 (9) ◽  
pp. E45-E50 ◽  
Author(s):  
Dai, Shimo ◽  
Zhang Shu ◽  
Guo Ying hua ◽  
Jianmin Chu ◽  
Wei Hua ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Dilated Cardiomyopathy ◽  
Idiopathic Dilated Cardiomyopathy ◽  
C Reactive Protein ◽  
Reactive Protein

C-reactive protein as a predictor of cardiovascular risk in HIV-infected individuals

Sexual Health ◽  
2014 ◽  
Vol 11 (6) ◽  
pp. 580 ◽  
Author(s):  
Clare L. V. Westhorpe ◽  
Hans G. Schneider ◽  
Mandy Dunne ◽  
Tracey Middleton ◽  
Vijaya Sundararajan ◽  
...  
Keyword(s):  
General Population ◽  
Hiv Infection ◽  
Predictive Value ◽  
High Sensitivity ◽  
Coronary Event ◽  
C Reactive Protein ◽  
Cardiac Events ◽  
Reactive Protein ◽  
Hs Crp ◽  
Study Participants

Background In some studies HIV infection confers approximately two-fold higher risk of cardiac events compared with the general population. C-reactive protein (CRP) is a well-characterised biomarker of cardiac events in the general population and is also elevated in patients with HIV infection. The aim of this study was to determine the predictive value of CRP for cardiac events in HIV-infected individuals. Methods: We retrospectively analysed CRP levels in stored plasma samples from HIV-infected patients who did or did not experience a coronary event in a case-controlled manner. All CRP measurements were performed using a high-sensitivity assay (hs-CRP). Results: Of the study participants with samples available, we found slightly elevated hs-CRP levels in the cardiac cases (median 3.5, IQR 1.6–14.4, n=23) compared with controls (median 2.6, IQR1.2–8.3, n=49) which were shown to not be statistically significant P=0.20. Analysis of CRP as a binary variable (≥5 mg L–1) was also not statistically significant (OR: 1.32, 95% CI 0.48–3.63). Conclusions: CRP levels may indicate elevated risk of future cardiac events, however this must be interpreted with caution due to the generalised elevation of CRP during HIV infection. CRP has no predictive value for atherosclerosis, and further research is required to improve early prediction of cardiovascular disease in HIV infection.

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