scholarly journals Efficacy of a Mediterranean diet supplemented with fatty fish in ameliorating inflammation in paediatric asthma: a randomised controlled trial

2018 ◽  
Vol 32 (2) ◽  
pp. 185-197 ◽  
Author(s):  
M. M. Papamichael ◽  
Ch. Katsardis ◽  
K. Lambert ◽  
D. Tsoukalas ◽  
M. Koutsilieris ◽  
...  
Keyword(s):  
Randomised Controlled Trial ◽  
Mediterranean Diet ◽  
Controlled Trial ◽  
Fatty Fish ◽  
Paediatric Asthma ◽  
Randomised Controlled

scholarly journals Mediterranean Diet Implementation to Protect against Advanced Lung Cancer Index (ALI) Rise: Study Design and Preliminary Results of a Randomised Controlled Trial

2021 ◽  
Vol 18 (7) ◽  
pp. 3700
Author(s):  
Aristea Gioxari ◽  
Dimitrios Tzanos ◽  
Christina Kostara ◽  
Panos Papandreou ◽  
Giannis Mountzios ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Randomised Controlled Trial ◽  
Nutritional Status ◽  
Mediterranean Diet ◽  
Controlled Trial ◽  
Small Cell ◽  
Advanced Lung Cancer ◽  
Study Endpoint ◽  
Preliminary Results ◽  
Randomised Controlled

The Mediterranean diet (MD) has been inversely associated with lung cancer (LC) risk. Hereby we show the preliminary results of our prospective randomised controlled trial in inflammatory and nutritional status of LC patients after 3-month implementation of MD. In total, 30 patients with small-cell or non-small-cell LC (stages III–IV) were enrolled. They were randomly assigned either to Control group, receiving general nutritional guidelines, or the MD group, in which a personalised MD plan was provided. Medical and dietary history, anthropometrics, blood biomarkers, and circulating antioxidant vitamins were assessed. The main outcome was a significantly higher advanced lung cancer inflammation index (ALI) in patients of the control arm than those following MD (p = 0.003). In the MD group, platelets were significantly reduced at the study endpoint (p = 0.044). BMI and body fat mass remained unchanged in both arms, but serum glucose was significantly higher in control compared to MD group (p = 0.017). In conclusion, we showed for the first time that implementing a personalised MD for 3 months is promising to regulate prognostic biomarkers in advanced LC. The final results of our on-going trial will shed a light on the inflammatory, antioxidant and nutritional status of LC patients following MD.

Can a Mediterranean diet reduce the effects of lipodystrophy syndrome in people living with HIV? A pilot randomised controlled trial

Sexual Health ◽  
2011 ◽  
Vol 8 (1) ◽  
pp. 43 ◽  
Author(s):  
Geraldine Wai Bik Ng ◽  
Una Man Shu Chan ◽  
Patrick Chung Ki Li ◽  
William C. W. Wong
Keyword(s):  
Pilot Study ◽  
Randomised Controlled Trial ◽  
Mediterranean Diet ◽  
Controlled Trial ◽  
Serum Triglyceride ◽  
Fat Distribution ◽  
Diet Group ◽  
Low Fat ◽  
Low Fat Diet ◽  
Randomised Controlled

Background: HIV and highly active antiretroviral therapies have been associated with changes in individuals’ lipid profiles and fat distribution (lipodystrophy). A pilot study was conducted for a randomised controlled trial to evaluate whether lipodystrophy in HIV patients can be controlled by adopting the low-fat and low-cholesterol diet or the modified Mediterranean diet. Methods: Forty-eight HIV patients were randomised into two diet groups. Thirty-six (75%) completed the 1-year pilot study with regular dietetic consultations, during which time lipid levels, weight, body mass index and fat distribution were recorded. Differences between and within groups were determined. Results: Undesirable body fat changes in the low-fat diet group included decreases in tricep skinfold (from 19.9 mm to 15.4 mm (P = 0.03)), hip circumference (from 93.6 cm to 91.7 cm (P = 0.01)) but a significant increase in waist-to-hip ratio (from 0.87 to 0.89 (P = 0.003)). Serum cholesterol increased significantly in the Mediterranean diet group at 9 and 12 months (from 4.6 to 5.06 mmol L−1 (P = 0.03) and 5.12 mmol L−1 (P = 0.01)) with no obvious change in the low-fat diet group. Serum triglyceride levels remained the same in the Mediterranean diet group, whereas it increased from 1.9 to 3.22 mmol L−1 (P = 0.07) in the low-fat diet group. Conclusions: A Mediterranean diet seems to have an advantage over the low-fat diet in maintaining serum triglyceride levels and avoiding lipodystrophy, but this advantage was offset by a rise in cholesterol level. Several procedural and methodological issues were identified which must be rectified before a similar large-scale trial taking place.

scholarly journals Improving paediatric asthma outcomes in primary health care: a randomised controlled trial

2011 ◽  
Vol 195 (7) ◽  
pp. 405-409 ◽  
Author(s):  
Smita Shah ◽  
Susan M Sawyer ◽  
Brett G Toelle ◽  
Craig M Mellis ◽  
Jennifer K Peat ◽  
...  
Keyword(s):  
Health Care ◽  
Primary Health Care ◽  
Randomised Controlled Trial ◽  
Controlled Trial ◽  
Paediatric Asthma ◽  
Primary Health ◽  
Asthma Outcomes ◽  
Randomised Controlled

scholarly journals The Mediterranean Diet and Cognitive Function among Healthy Older Adults in a 6-Month Randomised Controlled Trial: The MedLey Study

Nutrients ◽  
2016 ◽  
Vol 8 (9) ◽  
pp. 579 ◽  
Author(s):  
Alissa Knight ◽  
Janet Bryan ◽  
Carlene Wilson ◽  
Jonathan Hodgson ◽  
Courtney Davis ◽  
...  
Keyword(s):  
Older Adults ◽  
Cognitive Function ◽  
Randomised Controlled Trial ◽  
Mediterranean Diet ◽  
Controlled Trial ◽  
Healthy Older Adults ◽  
The Mediterranean ◽  
Randomised Controlled
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