scholarly journals Hearing test results of newborns born from the coronavirus disease 2019 ( COVID ‐19) infected mothers: A tertiary center experience in Turkey

Author(s):  
Gazi Yıldız ◽  
Didar Kurt ◽  
Emre Mat ◽  
Pınar Yıldız ◽  
Gülfem Başol ◽  
...  
2020 ◽  
Vol 38 (29_suppl) ◽  
pp. 223-223
Author(s):  
Spencer Soberano ◽  
Khaleeq Khan ◽  
Katrina Hueniken ◽  
Elyon Diekoloreoluwa Famoriyo ◽  
Joelle Soriano ◽  
...  

223 Background: Platinum-based chemotherapy agents cause significant hearing loss in 40-80% of treated cancer pts. Lack of follow-up serial testing has created gaps in knowledge regarding hearing loss onset, progression, and possible recovery between treatment cycles. This study aims to determine barriers and facilitators to implementation of a tablet-based point-of-care hearing test, as a serial screening tool to address these knowledge gaps. Methods: From Jul 2019 to Mar 2020, 53 pts receiving high dose platinum agents were recruited from three clinics (Thoracic, head and neck, and testicular cancer) at a comprehensive cancer centre, to undergo serial audiometry testing. Baseline hearing tests, mid cycles (3,6, and 9 weeks), and post treatment tests (3,6,9,12, 19 and 24 months) were completed during the pts’ clinic appointments. Clinical research coordinators (CRCs) collected feedback from physicians, nurses, and pts to identify barriers and facilitators of implementing serial point-of-care hearing tests in these clinics. An inductive and iterative approach was used to identify themes. Implementation was tailored and mapped to the CIHR Knowledge to Action Framework (KTA). Results: Barriers: Logistical barriers included: locating quiet and accessible rooms to administer the test; pts being distracted or interrupted while completing the test; presence of family members adding to noise levels; concerns over the serial testing during treatment; length of each test; and clinic staff burden. Facilitators: User-friendly self-administered tests; increasing healthcare staff education and pt management. Adapting to the local context: Logistical barriers were resolved by CRCs designating quiet spaces for the study to occur, and meeting pts upon arrival to utilize their wait time. A ‘hearing test in progress’ sign put on exam room doors prevented interruptions. CRCs utilized the test’s ‘assisted mode’ feature to keep pts attentive and/or accelerate the process. Low noise level was emphasized to obtain accurate test results. Pt engagement in their test results facilitated retention in the study. Test length may be shortened in the future by omitting low frequency testing. Conclusions: Participants and stakeholders expressed support for in-clinic hearing tests and identified personal and systemic barriers to implementation. These findings suggest that implementation should focus on addressing concerns related to accessible rooms, pt time investment and overall clinic flow.


1992 ◽  
Vol 35 (3) ◽  
pp. 211-222 ◽  
Author(s):  
Toshiaki O-Uchi ◽  
Akira Ogata ◽  
Hiroyasu Mashino ◽  
Shigemitsu Yoshihara ◽  
Yasuo Satoh ◽  
...  

Author(s):  
Betül Yakıştıran ◽  
Mehmet Karslı ◽  
Emre Canpolat ◽  
Yüksel Oğuz ◽  
Orhan Altınboğa ◽  
...  

Abstract Background Hearing is essential for the healthy development of an infant as language is one of the main stimulants of intellectual capacity. We investigate the effect of anesthesia type during delivery on neonatal otoacoustic emission (OAE) hearing test results. Methods This retrospective cross-sectional study includes 1,493 healthy, full-term (39/0–40/6 gestational weeks) newborns of healthy women and who were delivered by cesarean section. Newborns were divided into 2 groups based on their anesthesia type during delivery: 1) general anesthesia group (n=160), and 2) spinal anesthesia group (n=1333). Maternal age, anesthesia type, birth weight, gestational age at birth, neonatal gender, 1st–5th minute APGAR scores, and OAE results were compared between the groups. Results 1287 (86.2%) newborns were reported to have passed the first step of OAE; 206 (13.8%) newborns were reported to have failed the first step and passed the second test. In the general anesthesia group, 133 (83.1%) of the newborns passed the first OAE test and 27 (16.9%) newborns had false-positive results. In the spinal anesthesia group, 1,154 (86.6%) of the newborns passed the first OAE test and 179 (13.4%) newborns had false-positive results. The difference between the 2 groups by false-positive values was found to be statistically significant (p<0.001). Conclusions Type of delivery anesthesia may have an effect on the false-positive rates of OAE test results.


2021 ◽  
Vol 3 (1) ◽  
pp. 1-5
Author(s):  
Zeynep Gedik Özköse ◽  
Süleyman Cemil Oğlak ◽  
Mustafa Behram ◽  
Fatma Ölmez ◽  
Sema Süzen Çaypınar ◽  
...  

Objective: This study aimed to analyze the indications and outcomes of prenatal invasive diagnostic procedures performed in a single tertiary center. Materials and Methods: The invasive procedure indications and karyotype results of 1666 pregnant women who underwent prenatal invasive procedures between March 2016 and November 2018 were retrospectively analyzed. The indications and results of prenatal invasive diagnostic procedures were recorded. Results: Amniocentesis (AS) was performed to 1060 (63.6%) patients, corion villus sampling (CVS) to 299 (17.9%), and cordocentesis (CS) to 307 (18.4%) patients. Among the prenatal invasive procedure indications, the most frequent indication was abnormal ultrasound (US) findings, with a rate of 48.3% (n= 805). A normal karyotype was detected in 85% (n= 1416) of the cases, and chromosomal abnormality was detected in 12.2% (n= 204) of the cases. Abnormal karyotype results were found in 111 (10.5%) of 1060 patients who underwent AS, 87 (29.1%) of 299 patients who underwent CVS, and 52 (16.9%) of 307 patients who underwent CS. Among the numerical chromosomal abnormalities, trisomy 21 was the most common abnormality with a rate of 46% (94/204), while inversions were the most common abnormality of structural chromosomal abnormalities at 8.8% (18/204). Conclusion: The results of the current study show that AS is the most common prenatal diagnostic invasive procedure. We obtained the highest fetal chromosomal anomaly rate in patients who experienced CVS. Abnormal US findings were the most common prenatal invasive diagnostic procedure indication in our study. Choosing the most appropriate invasive procedure is related to the obstetricians' experience, medical history of the patient, the gestational week at admission, maternal prenatal serum screening test results, and abnormal US findings.


1993 ◽  
Vol 36 (2) ◽  
pp. 132-139
Author(s):  
Toshiaki O-Uchi ◽  
Akira Ogata ◽  
Hiroyasu Mashino ◽  
Shigemitsu Yoshihara ◽  
Yasuo Satoh ◽  
...  

2021 ◽  
Author(s):  
Alan Le Goallec ◽  
Samuel Diai ◽  
Theo Vincent ◽  
Chirag J Patel

With the aging of the world population, age-related hearing loss (presbycusis) and other hearing disorders such as tinnitus become more prevalent, leading to reduced quality of life and social isolation. Unveiling the genetic and environmental factors leading to age-related auditory disorders could suggest lifestyle and therapeutic interventions to slow auditory aging. In the following, we built the first machine learning-based hearing age predictor by training models to predict chronological age from hearing test results (root mean squared error=7.10+/-0.07 years; R-Squared=31.4+/-0.8%). We defined hearing age as the prediction outputted by the model on unseen samples, and accelerated auditory aging as the difference between a participant's hearing age and age. We then performed a genome wide association study [GWAS] and found that accelerated hearing aging is 14.1+/-0.4% GWAS-heritable. Specifically, accelerated auditory aging is associated with 662 single nucleotide polymorphisms in 243 genes (e.g OR2B4P, involved in smell perception). Similarly, it is associated with biomarkers (e.g cognitive tests), clinical phenotypes (e.g chest pain), diseases (e.g depression), environmental (e.g smoking, sleep) and socioeconomic (e.g income, education, social support) variables. The hearing age predictor could be used to evaluate the efficiency of emerging rejuvenation therapies on hearing.


1973 ◽  
Vol 82 (1) ◽  
pp. 13-16 ◽  
Author(s):  
Francis A. Sooy ◽  
Elmer Owens ◽  
Elizabeth S. Neufeld

This study was undertaken to determine the stability of hearing in patients over an eight-year period following a wire-vein graft stapedectomy procedure for otosclerosis. The method was to compare the four-month and eight-year postoperative hearing test results for a population of 76 patients who had undergone this procedure. No significant decrements in pure-tone thresholds were shown over the eight years for the speech frequencies (500, 1000, 2000 Hz). Decrements of approximately 0.5 dB and 1 dB per year over the eight-year period occurred for 4000 and 8000 Hz, respectively. These decrements did not seem to be associated with aging. A slight decrement of 2.8 percentage points in mean speech discrimination score was shown over the eight-year period, while no change occurred in mean speech reception threshold. There were no serious postoperative complications for this group of patients. These results indicated good stability of hearing over the eight years.


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