Increased risk of morbidities and health‐care utilisation in children born following preterm labour compared with full‐term labour: A population‐based study

Background and Aims: It is not known whether inflammatory bowel disease (IBD) enhances the risk of Parkinson’s disease (PD) or whether PD diagnosis is the result of increased health care use. We determined the risk of developing PD among patients with IBD in terms of health care and medication use. Methods: A nationwide population-based study was conducted using claims data from the Korean National Health care Insurance service. From 2010 to 2013, patients with Crohn’s disease (CD) and ulcerative colitis (UC) were identified through both International Classification of Disease, Tenth Revision (ICD-10) and national rare intractable disease (RID) registration program codes. We compared 38,861 IBD patients with age and sex-matched non-IBD individuals at a ratio of 1:3. Patients with newly diagnosed PD were identified through both ICD-10 and RID codes. Results: The incidence of PD among patients with IBD was 49 per 100,000 person-years. The risk of developing PD in patients with IBD was significantly higher than controls even after adjustment for health care use (adjusted hazard ratio (aHR), 1.87; P < 0.001). Compared to controls, the risk of PD was significantly higher in patients with CD (aHR, 2.23; P = 0.023) and UC (aHR, 1.85; P < 0.001). Corticosteroid use showed a preventive effect on developing PD in patients with CD (aHR 0.08; P < 0.001), but not UC (aHR, 0.75; P = 0.213). Among 2110 patients receiving anti-tumor necrosis factor (anti-TNF), none of the treated patients experienced PD during 9950 person-years. Conclusion: Patients with IBD are at an increased risk of PD, regardless of health care use. Corticosteroid and anti-TNF use may prevent PD in patients with IBD.

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The impact of changed treatment patterns in multiple myeloma on health care utilisation and costs, myeloma complications, and survival: a population‐based comparison between two time periods in Denmark

European Journal Of Haematology ◽

10.1111/ejh.13615 ◽

2021 ◽

Author(s):

Louise Hur Hannig ◽

Lene Kongsgaard Nielsen ◽

Rikke Ibsen ◽

Lisen Arnheim‐Dahlström ◽

Jakob Kjellberg ◽

...

Keyword(s):

Health Care ◽

Multiple Myeloma ◽

Population Based ◽

Health Care Utilisation ◽

Treatment Patterns ◽

Care Utilisation ◽

Time Periods ◽

The Impact

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Health care utilisation preceding relapse or second malignant neoplasm after childhood acute lymphoblastic leukaemia: a population-based matched cohort study

BMJ Open ◽

10.1136/bmjopen-2021-050285 ◽

2021 ◽

Vol 11 (8) ◽

pp. e050285

Author(s):

Karen Schow Jensen ◽

Birgitte Klug Albertsen ◽

Henrik Schrøder ◽

Alina Zalounina Falborg ◽

Kjeld Schmiegelow ◽

...

Keyword(s):

Health Care ◽

General Practice ◽

Malignant Neoplasm ◽

Population Based ◽

Health Care Utilisation ◽

Second Malignant Neoplasm ◽

Childhood All ◽

Bimodal Structure ◽

Childhood Acute Lymphoblastic Leukaemia ◽

Care Utilisation

ObjectivesTo investigate health care utilisation including both primary and secondary health care 6 months before the diagnosis of a relapse or a second malignant neoplasm (SMN) in survivors of childhood acute lymphoblastic leukaemia (ALL).Design and settingA Danish population-based matched cohort study linking multiple nationwide registries.ParticipantsParticipants were recruited from a total of 622 childhood ALL 2.5-year event-free survivors diagnosed between 1994 and 2015. Cases were survivors developing a relapse or an SMN and references were survivors still in first remission. Each case was matched with five references on age, sex, treatment protocol and risk group.Primary outcome measuresConsultations in general practice and hospital the last 6 months before relapse or SMN. Cases and references were compared with monthly incidence rate ratios (IRRs) from negative binomial regression models.ResultsOf the 622 childhood ALL survivors, 60 (9.6%) developed a relapse (49) or an SMN (11) and 295 matched references were identified. Health care utilisation in general practice increased among cases the last month before the event compared with references with an IRR of 2.71 (95% CI 1.71 to 4.28). Data showed a bimodal structure with a significantly increased number of visits 4, 5 and 6 months before the event. Hospital health care utilisation increased 2 months before the event in cases with an IRR of 5.01 (3.78 to 6.63) the last month before the event and an IRR of 1.94 (1.32 to 2.85) the second-last month comparing cases and references.ConclusionsSurvivors of childhood ALL developing a relapse or an SMN have a short period of increased health care utilisation before diagnosis. At hospital, this might be explained by pre-diagnostic examinations. In general practice, data suggest a bimodal structure with children later developing a relapse having more contacts also half a year before the relapse, suggesting that there could be early warnings.

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Increased Incidence of Critical Illness in Psoriasis

Journal of Cutaneous Medicine and Surgery ◽

10.1177/1203475417712497 ◽

2017 ◽

Vol 21 (5) ◽

pp. 395-400

Author(s):

Ruth Ann Marrie ◽

Charles N. Bernstein ◽

Christine A. Peschken ◽

Carol A. Hitchon ◽

Hui Chen ◽

...

Keyword(s):

Cox Regression ◽

Mortality Rates ◽

Population Based ◽

Incidence Rates ◽

Health Care Utilisation ◽

Matched Cohort ◽

Icu Admission ◽

Risk Of Mortality ◽

Care Utilisation ◽

Increased Risk

Background: Psoriasis is associated with an increased risk of comorbid disease. Despite the recognition of increased morbidity in psoriasis, the effects on health care utilisation remain incompletely understood. Little is known about the risk of intensive care unit (ICU) admission in persons with psoriasis. Objective: To compare the incidence of ICU admission and post-ICU mortality rates in a psoriasis population compared with a matched population without psoriasis. Methods: Using population-based administrative data from Manitoba, Canada, we identified 40 930 prevalent cases of psoriasis and an age-, sex-, and geographically matched cohort from the general population (n = 150 210). We compared the incidence of ICU admission between populations using incidence rates and Cox regression models adjusted for age, sex, socioeconomic status, and comorbidity and compared mortality after ICU admission. Results: Among incident psoriasis cases (n = 30 150), the cumulative 10-year incidence of ICU admission was 5.6% (95% confidence interval [CI], 5.3%-5.8%), 21% higher than in the matched cohort (incidence rate ratio, 1.21; 95% CI, 1.15-1.27). In the prevalent psoriasis cohort, crude mortality in the ICU was 11.5% (95% CI, 9.9%-13.0%), 32% higher than observed in the matched population admitted to the ICU (8.7%; 95% CI, 8.3%-9.1%). Mortality rates after ICU admission remained elevated at all time points in the psoriasis cohort compared with the matched cohort. Conclusion: Psoriasis is associated with an increased risk for ICU admission and with an increased risk of mortality post-ICU admission.

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Socio-economic inequalities in health care utilisation in Norway: a population based cross-sectional survey

BMC Health Services Research ◽

10.1186/1472-6963-12-336 ◽

2012 ◽

Vol 12 (1) ◽

Cited By ~ 26

Author(s):

Anne Helen Hansen ◽

Peder A Halvorsen ◽

Unni Ringberg ◽

Olav Helge Førde

Keyword(s):

Health Care ◽

Population Based ◽

Health Care Utilisation ◽

Cross Sectional Survey ◽

Cross Sectional ◽

Inequalities In Health ◽

Care Utilisation ◽

Economic Inequalities

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Characterizing mental health/addictions and assault visits in the year prior to death: a population-based linked cohort study of homicide victims

International Journal for Population Data Science ◽

10.23889/ijpds.v6i1.1410 ◽

2021 ◽

Vol 6 (1) ◽

Author(s):

Meghan O'Neill ◽

Emmalin Buajitti ◽

Peter D Donnelly ◽

Kathy Kornas ◽

Laura Rosella

Keyword(s):

Mental Health ◽

Health Care ◽

Population Based ◽

Health Care Utilisation ◽

Health Care Use ◽

Care Utilisation ◽

Older Youth ◽

Ed Visits ◽

One Year ◽

Utilisation Data

IntroductionHomicide is an important cause of death for older youth and adult Canadians; however, little is known about health care use prior to death among this population. ObjectivesTo characterise health care use for mental health and addictions (MHA) and serious assault (herein referred to assault) one year prior to death among individuals who died by homicide in Ontario, Canada using linked mortality and health care utilisation data. MethodsWe report rates of health care use for MHA and assault in the year prior to death among all individuals 16 years and older in Ontario, Canada, who died by homicide from April 2003 to December 2012 (N=1,541). Health care use for MHA included inpatient stays, emergency department (ED) visits and outpatient visits, whereas health care use for assault included only hospital-based care (ED visits and inpatient stays). Sociodemographic characteristics and health care utilisation were examined across homicide deaths, stratified by sex. ResultsOverall, 28.5% and 5.9% of homicide victims sought MHA and assault care in the year prior to death, respectively. A greater proportion of females accessed care for MHA, whereas a greater proportion of males accessed assault-related health care. Males were more likely to be hospitalised following an ED visit for a MHA or assault related reason, in comparison to females. The most common reason for a MHA hospital visit was for substance-related disorders. We found an increase over time for hospital-based visits for assault prior to death, a trend that was not observed for MHA-related visits. ConclusionsA large proportion of homicide victims interacted with the health care system for MHA or assault in the year prior to death. An increase in hospital-based visits for assault-related reasons prior to death was observed. These trends may offer insight into avenues for support and prevention for victims of homicide.

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