scholarly journals The key role of insomnia and sleep loss in the dysregulation of multiple systems involved in mood disorders: A proposed model

2019 ◽  
Vol 28 (6) ◽  
Author(s):  
Laura Palagini ◽  
Celyne H. Bastien ◽  
Donatella Marazziti ◽  
Jason G. Ellis ◽  
Dieter Riemann
Keyword(s):  
Mood Disorders ◽  
Sleep Loss ◽  
Multiple Systems ◽  
Proposed Model

Sleep markers in psychiatry: do insomnia and disturbed sleep play as markers of disrupted neuroplasticity in mood disorders? A proposed model

2021 ◽  
Vol 28 ◽  
Author(s):  
Laura Palagini ◽  
Pierre Alexis Geoffroy ◽  
Dieter Riemann
Keyword(s):  
Systematic Review ◽  
Mood Disorders ◽  
Neural Plasticity ◽  
Potential Role ◽  
Neuronal Damage ◽  
Brain Plasticity ◽  
Sleep Loss ◽  
Stress System ◽  
Disturbed Sleep ◽  
Proposed Model

Introduction: Since insomnia and disturbed sleep may affect neuroplasticity, we aimed at reviewing their potential role as markers of disrupted neuroplasticity involved in mood disorders. Method: We performed a systematic review, according to PRIMA, on PubMed, PsycINFO and Embase electronic databases for literature regarding mood disorders, insomnia, sleep loss/deprivation in relation to different pathways involved in the impairment of neuroplasticity in mood disorders such as 1] alterations in neurodevelopment 2] activation of the stress system 3] neuroinflammation 4] neurodegeneration/neuroprogression, 4] deficit in neuroprotection. Results: Sixty-five articles were analyzed and a narrative/ theoretical review was conducted. Studies showed that insomnia, sleep loss and sleep deprivation might impair brain plasticity of those areas involved in mood regulation throughout different pathways. Insomnia and disrupted sleep may act as neurobiological stressors that by over-activating the stress and inflammatory systems may affect neural plasticity causing neuronal damage. In addition, disturbed sleep may favor a deficit in neuroprotection hence contributing to impaired neuroplasticity. Conclusions: Insomnia and disturbed sleep may play a role as markers of alteration in brain plasticity in mood disorders. Assessing and targeting insomnia in the clinical practice may potentially play a neuroprotective role, contributing to “repairing” alterations in neuroplasticity or to the functional recovery of those areas involved in mood and emotion regulation.

1758-P: Type 2 Diabetes–Associated Mood Disorders: Role of Insulin Resistance in Serotonergic Neurons

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 1758-P
Author(s):  
HUGO MARTIN ◽  
SÉBASTIEN BULLICH ◽  
FABIEN DUCROCQ ◽  
MARION GRALAND ◽  
CLARA OLIVRY ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Type 2 Diabetes ◽  
Mood Disorders ◽  
Serotonergic Neurons ◽  
P Type

EMDR as therapy for conditions other than PTSD: a systematic review.

2020 ◽  
Author(s):  
Charles Scelles ◽  
LUIS CARLO BULNES
Keyword(s):  
Mood Disorders ◽  
Obsessive Compulsive ◽  
Treatment As Usual ◽  
Compulsive Disorder ◽  
Adult Personality ◽  
Post Traumatic ◽  
Psychiatric Conditions ◽  
Research Criteria ◽  
Positive Effect

Eye Movement Desensitization and Reprocessing (EMDR) is a treatment for post-traumatic stressdisorder (PTSD). The technique is known to stimulate the capacity to reprocess maladaptive memoriesthat are thought to be central to this pathology. Here we investigate if EMDR therapy can be used in otherconditions than PTSD. We conducted a systematic literature search on PubMed, ScienceDirect, Scopus, and Web of Science. Wesearched for published empirical findings on EMDR, excluding those centred on trauma and PTSD,published up to 2020. The results were classified by psychiatric categories.   Ninety articles met our research criteria. A positive effect was reported in addictions, somatoformdisorders, sexual dysfunction, eating disorder, disorders of adult personality, mood disorders, reaction tosevere stress, anxiety disorders, performance anxiety, Obsessive-Compulsive Disorder (OCD), pain,neurodegenerative disorders, paedopsychiatry and sleep. The evidence was more consistent in pain, OCD,mood disorders, and reaction to severe stress.EMDR’s efficiency across numerous pathological situations, highlighted the central role of affectivememory in several psychiatric and non-psychiatric conditions. Furthermore, EMDR seems to besuccessful in usually uncooperative (e.g. Dementia) or unproductive cases (e.g. aphasia). Moreover, insome severe medical situations were psychologic distress was an obstacle, EMDR allowed thecontinuation of treatment-as-usual. Our review suggests that it is a safe and economical therapeuticoption, and its effect in non-pathological situations opens new avenues for translational research. Overallmore methodologically rigorous studies are needed.

Social Networking Sites Continuance: An Application of Extended Theory of Planned Behaviour

2015 ◽  
Vol 8 (1) ◽  
Author(s):  
Himanshu Rajput
Keyword(s):  
Social Networking ◽  
Social Networking Sites ◽  
Theory Of Planned Behaviour ◽  
Standard Theory ◽  
Planned Behaviour ◽  
Privacy Concerns ◽  
Proposed Model ◽  
Continued Use ◽  
Moderating Role

Social networking sites (SNSs) have become popular in India with the proliferation of Internet. SNSs have gained the interests of academicians and researchers. The current study is an endeavor to understand the continuance of social networking sites in India. The study applies an extended version of theory of planned behavior. Additional factors privacy concerns and habits were incorporated into the standard theory of planned behaviour. A survey was conducted in a Central University in India. Overall, data was collected from 150 respondents. PLS-SEM was used to test the proposed model. All the hypotheses except the moderating role of habits between intentions and continued use of social networking sites, were supported by the results. Habits were found to affect continued use of social networking sites indirectly through continued intentions.

scholarly journals New neurons in the adult brain: The role of sleep and consequences of sleep loss

2009 ◽  
Vol 13 (3) ◽  
pp. 187-194 ◽  
Author(s):  
Peter Meerlo ◽  
Ralph E. Mistlberger ◽  
Barry L. Jacobs ◽  
H. Craig Heller ◽  
Dennis McGinty
Keyword(s):  
Sleep Loss ◽  
Adult Brain

Light-Induced Metastable Defects in a-Si:H: Towards an Understanding

1985 ◽  
Vol 49 ◽  
Author(s):  
Martin Stutzmann ◽  
Warren B. Jackson ◽  
Chuang Chuang Tsai
Keyword(s):  
Amorphous Silicon ◽  
Mechanical Stress ◽  
Hydrogenated Amorphous Silicon ◽  
Material Parameters ◽  
Kinetic Behaviour ◽  
Proposed Model ◽  
Special Cases ◽  
The Stability ◽  
Hydrogenated Amorphous

AbstractThe dependence of the creation and the annealing of metastable dangling bonds in hydrogenated amorphous silicon on various material parameters will be discussed in the context of a recently proposed model. After a brief review of the kinetic behaviour governing defect creation and annealing in undoped a- Si:H, a number of special cases will be analyzed: the influence of alloying with O, N, C, and Ge, changes introduced by doping and compensation, and the role of mechanical stress. Finally, possibilities to increase the stability of a-Si:H based devices will be examined.

On the role of the anthropocentric factor in the realization of the derivational potential of names of ungulates as motivating lexical units

2021 ◽  
pp. 191-210
Author(s):  
Nikolay D. Golev ◽  
◽  
Irina P. Falomkina ◽  
Keyword(s):  
Native Speakers ◽  
Russian Language ◽  
Search System ◽  
Proposed Model ◽  
Data Capturing ◽  
Building Behavior ◽  
Building System ◽  
Google Search ◽  
The Russian Language

The paper is dedicated to describing the word-building system of the Russian language in terms of its vocabulary. Lexical factors are discussed influencing the formation of lexical units’ potential as motivating units of word-building processes and relations and the realization of this potential in language activities. Of most interest for the authors are anthropocentric determinants, most of which are coordinating the lexical system and, through its mediation, the word-building system with the worldview of native speakers of the Russian language. The proposed model of derivational development of vocabulary provides such coordination through studying the deep-seated process of conceptualization of the words that are the potential motivators of neologisms. This study identifies the word frequency as an external manifestation of conceptualization. The frequency data were obtained from Google search system statistical data. Capturing not only usual but also occasional and potential words, this source is an effective tool for studying word-building processes and their results. This study has unveiled the interrelation between the language worldview of native speakers of Russian and their “word-building behavior” in language activities. The worldview has been found, first of all, to be determined by the pragmatic factor, which primarily influences the usage of a word in the speech reflected by its frequency. The frequency ranks lexical units due to their derivational potential and thereby provides a researcher with a reliable instrument for its study.

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