What is your diagnosis? Subcutaneous mass on the head of a dog

SummaryA 2-year-old male neutered mixed breed dog with a body weight of 30 kg was presented for evaluation of a soft subcutaneous mass on the dorsal midline at the level of the caudal thoracic spine. A further clinical sign was intermittent pain on palpation of the area of the subcutaneous mass. The owner also described a prolonged phase of urination with repeated interruption and re-initiation of voiding. The findings of the neurological examination were consistent with a lesion localization between the 3rd thoracic and 3rd lumbar spinal cord segments. Magnetic resonance imaging revealed a spina bifida with a lipomeningocele and diplomyelia (split cord malformation type I) at the level of thoracic vertebra 11 and 12 and secondary syringomyelia above the aforementioned defects in the caudal thoracic spinal cord. Surgical resection of the lipomeningocele via a hemilaminectomy was performed. After initial deterioration of the neurological status postsurgery with paraplegia and absent deep pain sensation the dog improved within 2 weeks to non-ambulatory paraparesis with voluntary urination. Six weeks postoperatively the dog was ambulatory, according to the owner. Two years after surgery the owner recorded that the dog showed a normal gait, a normal urination and no pain. Histopathological diagnosis of the biopsied material revealed a lipomeningocele which confirmed the radiological diagnosis.

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Chalastospora gossypii in a Maine Coon cat: case report and literature review

Journal of Veterinary Diagnostic Investigation ◽

10.1177/10406387211022298 ◽

2021 ◽

pp. 104063872110222

Author(s):

Samantha M. Norris ◽

Paula A. Schaffer ◽

Noah B. Bander

Keyword(s):

Soft Tissue ◽

Needle Aspiration ◽

Tissue Mass ◽

Large Numbers ◽

Formalin Fixed Paraffin ◽

Formalin Fixed Paraffin Embedded ◽

Soft Tissue Masses ◽

Subcutaneous Mass ◽

The Right ◽

A Minor

A 15-y-old castrated male Maine Coon cat was evaluated for an ulcerated soft tissue mass on the right hindlimb that had been observed for 4 mo and had grown rapidly. A 3 × 3 cm soft, raised, amorphous, and ulcerated subcutaneous mass was observed on the lateral right metatarsus. In-house cytology via fine-needle aspiration was nondiagnostic. Incisional biopsy of the mass and further staging was declined, and amputation was elected. The amputated limb was submitted for histopathology, which revealed severe chronic nodular granulomatous dermatitis and multifocal granulomatous popliteal lymphadenitis with large numbers of intralesional fungal hyphae. Fungal PCR and sequencing on formalin-fixed, paraffin-embedded tissue identified Chalastospora gossypii. No adjunctive therapy was elected at the time. The patient has done well clinically 1 y post-operatively. C. gossypii is a rare microfungus found worldwide and is considered a minor pathogen of several plants. To our knowledge, infection by this fungus has not been reported previously in veterinary species. Features in our case are comparable to other mycotic infections. Nodular granulomatous mycotic dermatitis and cellulitis, although uncommon, should be a differential for soft tissue masses in veterinary species; C. gossypii is a novel isolate.

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Endometriosis of Rectus Muscle Excised During Cesarean Section: A Case Report and Literature Review

Gynecology Obstetrics and Reproductive Medicine ◽

10.21613/gorm.2016.489 ◽

2016 ◽

Author(s):

Recep Erin ◽

Kübra Baki Erin ◽

Derya Burkankulu Ağırbaş ◽

Burcu Kemal Okatan

Keyword(s):

Case Report ◽

Pregnant Woman ◽

Literature Review ◽

Cesarean Section ◽

Abdominal Wall ◽

Rectus Muscle ◽

Surgical Excision ◽

Treatment Method ◽

Abdominal Wall Endometriosis ◽

Subcutaneous Mass

We aimed to present a case with abdominal wall endometriosis following cesarean section in this case report. A 32 year old 39 weeks pregnant woman with G2P1 was admitted to gynaecology clinic with abdominal lump and pain in the midline. Her physical examination included a hard and painful palpable subcutaneous mass of 4x5 cm size in the midline of the abdomen which was semisolid and irreducible. Under general anesthesia, the mass on the rectus muscle was excised with the healthy tissue around with the diagnosis of endometriosis during cesarean section and the pathological diagnosis was reported as endometriosis. Surgical excision is the best treatment method in abdominal wall endometriosis.

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Soft thoracic subcutaneous mass in a rabbit (Oryctolagus cuniculus)

Lab Animal ◽

10.1038/laban1011-300 ◽

2011 ◽

Vol 40 (10) ◽

pp. 300-301 ◽

Cited By ~ 2

Author(s):

Hany Elsheikha ◽

Peter Brown ◽

Ben Middleton

Keyword(s):

Oryctolagus Cuniculus ◽

Subcutaneous Mass

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INTRACRANIAL COMPLICATIONS OF CONGENITAL DERMAL SINUSES

PEDIATRICS ◽

10.1542/peds.8.4.463 ◽

1951 ◽

Vol 8 (4) ◽

pp. 463-474

Author(s):

DONALD D. MATSON ◽

FRANC D. INGRAHAM

Keyword(s):

Surgical Treatment ◽

Intracranial Extension ◽

Dermal Sinus ◽

Skull Defect ◽

Complete Cure ◽

Neural Axis ◽

Intracranial Complications ◽

Subcutaneous Mass ◽

Sinus Opening ◽

Congenital Dermal Sinus

Ten patients are presented in whom intracranial extension of a congenital dermal sinus was disclosed by operation. The complications of this lesion include infection in the form of meningitis, abscess formation and osteomyelitis as well as hydrocephalus due to obstruction of the spinal fluid pathways. In unexplained meningitis, the entire midline area of skin over the neural axis should be examined carefully for evidence of a dermal sinus opening. Whenever a dimple or subcutaneous mass is found in the midline of the scalp, RGs should be examined carefully for an underlying skull defect. When such a defect exists, intracranial exploration is indicated. Surgical treatment previous to development of intracranial infection is relatively simple and should be rewarded by complete cure. Excision after infection has occurred is difficult and the results in this group have been poor.

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Hypophosphatemic Osteomalacia associated with Neurofibromatosis Type-1: A case report and literature review

Global Neurology ◽

10.36879/gon.20.000109 ◽

2020 ◽

pp. 1-3

Keyword(s):

Neurofibromatosis Type 1 ◽

Bone Matrix ◽

Neurofibromatosis Type ◽

Lower Limbs ◽

Laboratory Evaluation ◽

Lumbosacral Spine ◽

Café Au Lait Spots ◽

Hypophosphatemic Osteomalacia ◽

Subcutaneous Mass

Introduction: Skeleton abnormalities are not uncommon in neurofibromatosis type-1 (NF1), which usually manifest as congenital malformations, such as scoliosis and sphenoid wing dysplasia. However, very rare cases of NF1 have been associated with hypophosphatemic osteomalacia (HO), which is characterized with later onset in adulthood, severe hypophosphatemia and disorder of the mineralization of organic bone matrix. Patient concerns: Here we reported a rare case of a 29-year-old woman presented with weakness and pain in lower limbs for 18 months and aggravated for half a year. On physical examination, her lower limbs’ myodynamia reduced and tenderness in multiple bone areas was detected. Light brown patches and scattered nodules could be seen on her skin, and a soft subcutaneous mass was found in the low back. Laboratory evaluation showed hypophosphatemia. Bone ECT suggested multiple abnormal bone metabolism and MRI scan of lumbosacral spine revealed numerous fractures. Neuroimaging indicated the neurofibromas, and then the biopsy of the subcutaneous lump confirmed neurofibromatosis. Diagnosis: HO associated with NF1 was diagnosed, based on the presence of café-au-lait spots and the results of bone ECT scan and biopsy. Interventions: The patient was treated with oral calcitriol, calcium carbonate d3 and phosphorus, as well as intramuscular carbocalcitonin. Outcomes: During hospitalization, her serum phosphorus level increased and symptoms improved. Conclusion: The case reported here calls attention to that when NF1 patients manifested with weakness and neurology diseases have been excluded, HO should be taken into consideration.

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Spina Bifida Associated with Subcutaneous Mass, Dural Ectasia and Thin Thoracic Spinal Cord

Annual Review of Hydrocephalus ◽

10.1007/978-3-662-11158-1_96 ◽

1991 ◽

pp. 150-151

Author(s):

Takamichi Yuguchi ◽

Kazuyoshi Morimoto ◽

Toshiki Yoshimine ◽

Amami Kato ◽

Yoshiyuki Masana ◽

...

Keyword(s):

Spinal Cord ◽

Spina Bifida ◽

Thoracic Spinal Cord ◽

Dural Ectasia ◽

Thoracic Spinal ◽

Subcutaneous Mass

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Successful treatment of an adult with Kasabach-Merritt syndrome using thalidomide, vincristine, and prednisone

Journal of International Medical Research ◽

10.1177/0300060519830242 ◽

2019 ◽

Vol 47 (4) ◽

pp. 1810-1814

Author(s):

Yue-Hua Huang ◽

Dao-Bin Zhou ◽

Bing Han ◽

Tian Li ◽

Shu-Jie Wang

Keyword(s):

Treatment Regimen ◽

Disseminated Intravascular Coagulation ◽

Tumor Regression ◽

Severe Bleeding ◽

Intravascular Coagulation ◽

Subcutaneous Mass ◽

Low Incidence ◽

Disease Free ◽

Novel Therapeutic

Objective Kasabach-Merritt syndrome is a rare disease that mainly occurs in infants and adolescents. It usually manifests as disseminated intravascular coagulation and severe bleeding, and is associated with high mortality. However, its low incidence and clinical rarity in adults mean that there is currently no well-verified treatment regimen for this disease. We report on an effective novel therapeutic regimen in a patient with Kasabach-Merritt syndrome. Methods A woman with Kasabach-Merritt syndrome presented with a recurrent subcutaneous mass and disseminated intravascular coagulation, and was treated with prednisone, vincristine and thalidomide. Results This treatment regimen successfully resolved the patient’s symptoms, with tumor regression. The patient remained disease-free after 6 years of follow-up. Conclusions Prednisone combined with vincristine and thalidomide may be an effective treatment for Kasabach-Merritt syndrome, but further studies are needed to verify the use of this regimen.

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An Unusual Presentation of Merkel Cell Carcinoma in a HIV Patient: A Case Report and Literature Review

Journal of Investigative Medicine High Impact Case Reports ◽

10.1177/2324709619836695 ◽

2019 ◽

Vol 7 ◽

pp. 232470961983669

Author(s):

Preethi Ramachandran ◽

Burak Erdinc ◽

Vladimir Gotlieb

Keyword(s):

Cell Carcinoma ◽

Merkel Cell Carcinoma ◽

Target Therapy ◽

Palliative Radiotherapy ◽

Unusual Presentation ◽

Merkel Cell ◽

Advanced Stages ◽

Subcutaneous Mass ◽

Aggressive Tumors ◽

Head Neck

Merkel cell carcinoma (MCC) is a rare, rapidly growing, aggressive neuroendocrine skin cancer that generally arises on sun-exposed areas of body such as head, neck, upper limbs, and shoulders of people with light complexity. Typically, MCC presents as shiny, flesh-colored or bluish-red, intracutaneous nodule, possibly with ulceration or crusting. In most of the cases, there is an association with Merkel cell polyomavirus. Even though these are very aggressive tumors, early detection and treatment has always given favorable outcome. There seems to be no consensus in definite prognostic markers, and advanced stages have the worst outcome even with treatment. There has been a recent trend in using PD-I/PD-L1 target therapy rather than chemotherapy in these cancers and have shown to improve survival by many months. In this article, we report a very unusual presentation of MCC first found on left frontoparietal skull as an 8-cm diameter fixed, subcutaneous mass without any typical features of MCC and was found to have metastatic spread to lung and liver. The patient was treated with palliative radiotherapy to brain and chemotherapy with cisplatin/etoposide with addition of immunotherapy later.

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Cutaneous mastocytoma with eosinophilia and eosinophilic infiltration of the small intestine in an Arabian gelding

Veterinary Record Case Reports ◽

10.1136/vetreccr-2018-000773 ◽

2020 ◽

Vol 8 (1) ◽

pp. e000773

Author(s):

Natasha Jane Williams ◽

Robin van den Boom

Keyword(s):

Small Intestine ◽

Tendon Sheath ◽

Needle Aspiration ◽

Eosinophilic Infiltration ◽

Mesenteric Root ◽

Flexor Tendon Sheath ◽

Subcutaneous Mass ◽

Small Intestinal ◽

The Right ◽

The University

A 12-year-old Arabian gelding presented to the University of Adelaide for investigation of a firm subcutaneous mass, just proximal to the digital flexor tendon sheath of the right forelimb, that had appeared two weeks prior. The skin overlying the mass was intact. Fine needle aspiration identified eosinophilic and mastocytic infiltrates. One week later, the gelding re-presented for persistent colic signs. Blood examination showed eosinophilia, and on palpation per rectum the mesenteric root was very firm and enlarged and a number of small intestinal loops had subjectively thickened walls. Colic signs were unabated by the administration of pain relief. The owner declined surgery and the gelding was euthanased. Postmortem examination confirmed a diagnosis of cutaneous mastocytoma and revealed eosinophilic infiltration of the small intestine.

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