Biomechanical Evaluation of an Endplate-Conformed Polycaprolactone-Hydroxyapatite Intervertebral Fusion Graft and Its Comparison With a Typical Nonconformed Cortical Graft

2013 ◽  
Vol 135 (6) ◽  
Author(s):  
Aakash Agarwal ◽  
Vivek Palepu ◽  
Anand K. Agarwal ◽  
Vijay K. Goel ◽  
Eda D. Yildirim

In the thoracolumbar region, between 7% and 30% of spinal fusion failures are at risk for pseudarthrosis. From a biomechanical perspective, the nonconformity of the intervertebral graft to the endplate surface could contribute to pseudarthrosis, given suboptimal stress distributions. The objective of this study was to quantify the effect of endplate-graft conformation on endplate stress distribution, maximum Von Mises stress development, and stability. The study design used an experimentally validated finite element (FE) model of the L4–L5 functional spinal unit to simulate two types of interbody grafts (cortical bone and polycaprolactone (PCL)-hydroxyapatite (HA) graft), with and without endplate-conformed surfaces. Two case studies were completed. In Case Study I, the endplate-conformed grafts and nonconformed grafts were compared under without posterior instrumentation condition, while in Case Study II, the endplate-conformed and nonconformed grafts were compared with posterior instrumentation. In both case studies, the results suggested that the increased endplate-graft conformity reduced the maximum stress on the endplate, created uniform stress distribution on endplate surfaces, and reduced the range of motion of L4–L5 segments by increasing the contact surface area between the graft and the endplate. The stress distributions in the endplate suggest that the load sharing is greater with the endplate-conformed PCL-HA graft, which might reduce the graft subsidence possibility.

Nanomaterials ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. 1708 ◽  
Author(s):  
Maciej Zarow ◽  
Mirco Vadini ◽  
Agnieszka Chojnacka-Brozek ◽  
Katarzyna Szczeklik ◽  
Grzegorz Milewski ◽  
...  

By means of a finite element method (FEM), the present study evaluated the effect of fiber post (FP) placement on the stress distribution occurring in endodontically treated upper first premolars (UFPs) with mesial–occlusal–distal (MOD) nanohybrid composite restorations under subcritical static load. FEM models were created to simulate four different clinical situations involving endodontically treated UFPs with MOD cavities restored with one of the following: composite resin; composite and one FP in the palatal root; composite and one FP in the buccal root; or composite and two FPs. As control, the model of an intact UFP was included. A simulated load of 150 N was applied. Stress distribution was observed on each model surface, on the mid buccal–palatal plane, and on two horizontal planes (at cervical and root-furcation levels); the maximum Von Mises stress values were calculated. All analyses were replicated three times, using the mechanical parameters from three different nanohybrid resin composite restorative materials. In the presence of FPs, the maximum stress values recorded on dentin (in cervical and root-furcation areas) appeared slightly reduced, compared to the endodontically treated tooth restored with no post; in the same areas, the overall Von Mises maps revealed more favorable stress distributions. FPs in maxillary premolars with MOD cavities can lead to a positive redistribution of potentially dangerous stress concentrations away from the cervical and the root-furcation dentin.


Volume 1 ◽  
2004 ◽  
Author(s):  
M. M. Villar ◽  
M. M. Pe´rez

In this paper a numerical model is used to investigate the effect of the elasticity of the bearing in the pressure distribution in the lubricant and the stress distribution in the bearing. The lubricant film, as well as a bearing, including the lining and the backing of the insert, and the housing, are modeled using the general-purpose ANSYS®5.7 commercial Finite Element program. Results have been obtained for the pressure, radial displacement, hoop and von Mises stress distributions at the surface of the bearing, as well as for the shear stress distribution at the interface between the lining and the backing. A number of conclusions have been drawn regarding the relative significance of the steep pressure gradient at the end of the lubricated region on the hoop stresses that cause localized bending distortions at the surface of the lining. These localized bending distortions, in turn, are likely to cause fatigue failure of the lining.


2019 ◽  
Vol 9 (2) ◽  
pp. 303
Author(s):  
Wenke Huang ◽  
Zhibin Ren ◽  
Xiaoning Zhang ◽  
Jiangmiao Yu

This paper presents an image-based micromechanical modeling approach for simulating the damage-couple viscoelastic response of asphalt mixture. Details of the numerical damage-couple viscoelastic constitutive formulation implemented in a finite element code are presented and illustrated by using the ABAQUS user material subroutine (UMAT). Then, an experimental procedure based on the Linear Amplitude Sweep test for obtaining the viscoelastic and damage parameters at a given temperature was conducted. An improved morphological multi-scale algorithm was employed to segment the adhesive coarse aggregate images. We developed a pixel-based digital reconstruction model of asphalt mixture with the X-ray CT image after being processed. Finally, the image-based FE model incorporated with damage-coupled viscoelastic asphalt mastic phase and elastic aggregates was used for the compressive test simulations successfully in this study. Simulation results showed that the damaged simulation results have a larger stress distribution compared with the undamaged simulation due to the irregularity of the coarse aggregates. The von Mises stress distribution is smaller as the loading time increases due to the viscoelastic behavior of asphalt mastic. It can also provide insight on the damaged mechanisms and the possible location in asphalt mixture where microscopic cracking would most likely occur.


Author(s):  
Haoliang Jiang ◽  
Zhenguo Nie ◽  
Roselyn Yeo ◽  
Amir Barati Farimani ◽  
Levent Burak Kara

Abstract Using deep learning to analyze mechanical stress distributions has been gaining interest with the demand for fast stress analysis methods. Deep learning approaches have achieved excellent outcomes when utilized to speed up stress computation and learn the physics without prior knowledge of underlying equations. However, most studies restrict the variation of geometry or boundary conditions, making these methods difficult to be generalized to unseen configurations. We propose a conditional generative adversarial network (cGAN) model for predicting 2D von Mises stress distributions in solid structures. The cGAN learns to generate stress distributions conditioned by geometries, load, and boundary conditions through a two-player minimax game between two neural networks with no prior knowledge. By evaluating the generative network on two stress distribution datasets under multiple metrics, we demonstrate that our model can predict more accurate high-resolution stress distributions than a baseline convolutional neural network model, given various and complex cases of geometry, load and boundary conditions.


2018 ◽  
Vol 15 (138) ◽  
pp. 20170844 ◽  
Author(s):  
Liang Liang ◽  
Minliang Liu ◽  
Caitlin Martin ◽  
Wei Sun

Structural finite-element analysis (FEA) has been widely used to study the biomechanics of human tissues and organs, as well as tissue–medical device interactions, and treatment strategies. However, patient-specific FEA models usually require complex procedures to set up and long computing times to obtain final simulation results, preventing prompt feedback to clinicians in time-sensitive clinical applications. In this study, by using machine learning techniques, we developed a deep learning (DL) model to directly estimate the stress distributions of the aorta. The DL model was designed and trained to take the input of FEA and directly output the aortic wall stress distributions, bypassing the FEA calculation process. The trained DL model is capable of predicting the stress distributions with average errors of 0.492% and 0.891% in the Von Mises stress distribution and peak Von Mises stress, respectively. This study marks, to our knowledge, the first study that demonstrates the feasibility and great potential of using the DL technique as a fast and accurate surrogate of FEA for stress analysis.


2020 ◽  
Author(s):  
Konghe Hu ◽  
Jianjun Li ◽  
Sujun Qiu ◽  
Yingmin Xie ◽  
Kaiqin Gong ◽  
...  

Abstract Objective: The purpose of this study was to analyze the biomechanical characteristics of the lumbar posterior dynamic devices: the Dynesys system and the BioFlex system. Methods: We validated the FE model of an lumbar spine (L3-S1) established by transferring the data, collected by 3D CT scan, to the FE software ABAQUS and comparing these data with the data from published studies. Then, were reconstructed by the lumbar posterior dynamic devices to analyze the range of motion (ROM) and stress distribution on the lumbar posterior dynamic devices. Results: The current lumbar FE model was able to measure the biomechanical changes in a follow-up surgery simulation. The total ROM of the surgery simulation models was substantially decreased compared with the total ROM of the intact group, and the Dynesys system group had the closest total ROM to the intact group. The maximal von Mises stress concentrate at the middle part of the screws in Dynesys system, but at the Nitinol memory loop in BioFlex system. The maximal stress level was only 49 MPa in Dynesys system, but 164 MPa in BioFlex system. Conclusion: Through the comparison of ROM and the stress distribution of the prosthesis, we find that the Dynesys system maybe has a better theoretical outcome.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Charles Savoldelli ◽  
Elodie Ehrmann ◽  
Yannick Tillier

AbstractWith modern-day technical advances, high sagittal oblique osteotomy (HSOO) of the mandible was recently described as an alternative to bilateral sagittal split osteotomy for the correction of mandibular skeletal deformities. However, neither in vitro nor numerical biomechanical assessments have evaluated the performance of fixation methods in HSOO. The aim of this study was to compare the biomechanical characteristics and stress distribution in bone and osteosynthesis fixations when using different designs and placing configurations, in order to determine a favourable plating method. We established two finite element models of HSOO with advancement (T1) and set-back (T2) movements of the mandible. Six different configurations of fixation of the ramus, progressively loaded by a constant force, were assessed for each model. The von Mises stress distribution in fixations and in bone, and bony segment displacement, were analysed. The lowest mechanical stresses and minimal gradient of displacement between the proximal and distal bony segments were detected in the combined one-third anterior- and posterior-positioned double mini-plate T1 and T2 models. This suggests that the appropriate method to correct mandibular deformities in HSOO surgery is with use of double mini-plates positioned in the anterior one-third and posterior one-third between the bony segments of the ramus.


2014 ◽  
Vol 136 (11) ◽  
Author(s):  
Jacob T. Munro ◽  
Justin W. Fernandez ◽  
James S. Millar ◽  
Cameron G. Walker ◽  
Donald W. Howie ◽  
...  

Periprosthetic osteolysis in the retroacetabular region with cancellous bone loss is a recognized phenomenon in the long-term follow-up of total hip replacement. The effects on load transfer in the presence of defects are less well known. A validated, patient-specific, 3D finite element (FE) model of the pelvis was used to assess changes in load transfer associated with periprosthetic osteolysis adjacent to a cementless total hip arthroplasty (THA) component. The presence of a cancellous defect significantly increased (p < 0.05) von Mises stress in the cortical bone of the pelvis during walking and a fall onto the side. At loads consistent with single leg stance, this was still less than the predicted yield stress for cortical bone. During higher loads associated with a fall onto the side, highest stress concentrations occurred in the superior and inferior pubic rami and in the anterior column of the acetabulum with larger cancellous defects.


Author(s):  
Z Yi ◽  
WZ Fu ◽  
MZ Li

In order to obtain a higher pressure capacity for the high-pressure die with a larger sample cavity, two types of two-layer split dies with a round cylinder and a quadrate cylinder were designed based on the conventional belt-type die. Finite element analysis was performed to investigate the stress distributions and pressure capacities of the high-pressure dies using a derived Mohr–Coulomb criterion and the von Mises criterion for the cylinder and supporting rings, respectively. As predicted by the finite element analysis results, in the two-layer split dies with a round cylinder, the stress state of the cylinder can be only slightly improved; and the von Mises stress of the first layer supporting ring can be hardly decreased. However, in the two-layer split dies with a quadrate cylinder and sample cavity, the stress state of the cylinder can be remarkably improved. Simultaneously, the von Mises stress of the supporting rings, especially for the first-layer supporting ring, can be also effectively decreased. The pressure capacities of the two-layer split dies with a round cylinder and a quadrate cylinder are 16.5% and 63.9% higher with respect to the conventional belt-type die.


2019 ◽  
Vol 18 (1) ◽  
Author(s):  
WeiLun Yu ◽  
XiaoGang Wu ◽  
HaiPeng Cen ◽  
Yuan Guo ◽  
ChaoXin Li ◽  
...  

Abstract Background Bone is a hierarchically structured composite material, and different hierarchical levels exhibit diverse material properties and functions. The stress and strain distribution and fluid flow in bone play an important role in the realization of mechanotransduction and bone remodeling. Methods To investigate the mechanotransduction and fluid behaviors in loaded bone, a multiscale method was developed. Based on poroelastic theory, we established the theoretical and FE model of a segment bone to provide basis for researching more complex bone model. The COMSOL Multiphysics software was used to establish different scales of bone models, and the properties of mechanical and fluid behaviors in each scale were investigated. Results FE results correlated very well with analytical in macroscopic scale, and the results for the mesoscopic models were about less than 2% different compared to that in the macro–mesoscale models, verifying the correctness of the modeling. In macro–mesoscale, results demonstrated that variations in fluid pressure (FP), fluid velocity (FV), von Mises stress (VMS), and maximum principal strain (MPS) in the position of endosteum, periosteum, osteon, and interstitial bone and these variations can be considerable (up to 10, 8, 4 and 3.5 times difference in maximum FP, FV, VMS, and MPS between the highest and the lowest regions, respectively). With the changing of Young’s modulus (E) in each osteon lamella, the strain and stress concentration occurred in different positions and given rise to microscale spatial variations in the fluid pressure field. The heterogeneous distribution of lacunar–canalicular permeability (klcp) in each osteon lamella had various influence on the FP and FV, but had little effect on VMS and MPS. Conclusion Based on the idealized model presented in this article, the presence of endosteum and periosteum has an important influence on the fluid flow in bone. With the hypothetical parameter values in osteon lamellae, the bone material parameters have effect on the propagation of stress and fluid flow in bone. The model can also incorporate alternative material parameters obtained from different individuals. The suggested method is expected to provide dependable biological information for better understanding the bone mechanotransduction and signal transduction.


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