Micro-PIV Measurement on Transient Flows in Pneumatic MEMS Device for Cell Trapping

Author(s):  
Hyun Dong Kim ◽  
Kyung Chun Kim

This paper presents a micro-PIV measurement for investigation of flow characteristics in a micro chamber for trapping of a live cell. The micro cell chip consisting of pneumatic vibrator arrays and a trap chamber was fabricated through a replica molding technology with a SU-8 mold and Polydimethylsiloxane (PDMS) polymer. The single cell in the trap chamber was manipulated and trapped in the equilibrium region by exploiting the geometrical symmetry of the vibrators. The x-axial velocity of the viscous fluid induced by the deformation of the flexible diaphragms was eliminated or minimized at the center of vibrators. From the measurement results, the proper operational conditions of the vibrators were determined and it is also verified that the particle can be actively manipulated and trapped as desired.

Author(s):  
Keizo Watanabe ◽  
Satoshi Ogata ◽  
Munehiko Hirao

Pressure drops and velocity profiles for micro tubes were investigated for the laminar flow of distilled water and dilute polymer solutions. The test micro tubes were fused silica capillaries with diameters in the range of 50.2–251.8 μm, and a value of l/d (length/diameter) of about 340. By performing pressure drop measurements, it is shown that the experimental data agree well with the Hagen-Poiseuille equation in the case of Newtonian fluids. On the other hand, the flow rate of dilute polymer solutions increases relative to that of distilled water in the low Reynolds number range. The increased flow rate ratio is a maximum of about 15% in the case of d = 251.8 μm. For the result of the micro PIV measurement, however, there are few differences between the velocity profile of distilled water and the Peo 5 ppm solution.


2015 ◽  
Vol 137 (6) ◽  
Author(s):  
Qiaorui Si ◽  
Patrick Dupont ◽  
Annie-Claude Bayeul-Lainé ◽  
Antoine Dazin ◽  
Olivier Roussette ◽  
...  

Measurements are processed on a centrifugal pump model, which works with air and performs with the vane-island type diffuser of a real hydraulic pump, under five flow rates to investigate the internal flow characteristics and their influence on overall pump performance. The mean flow characteristics inside the diffuser are determined by using a miniature three-hole probe connected to an online data acquisition system. The flow structure at the inlet section of the diffuser is analyzed in detail, with a focus on the local pressure loss inside the vaneless gap and incidence angle distributions along the hub-to-shroud direction of the diffuser. Some existing calculations, including leakage effects, are used to evaluate the pressure recovery downstream of the impeller. Furthermore, particle image velocimetry (PIV) measurement results are obtained to help analyze the flow characteristics inside the vane-island diffuser. Each PIV measuring plane is related to one particular diffuser blade-to-blade channel and is analyzed by using the time-averaged method according to seven different relative positions of the impeller. Measurement results show that main loss is produced inside the vaneless part of the diffuser at low flow rates, which might have been caused by the strong rotor–stator interaction. When the impeller flow rate is greater than the diffuser design flow rate, a large fluctuating separated region occurs after the throat of the diffuser on the pressure side. Mean loss originates from the unsteady pressure downstream of the diffuser throat. For better characterization of the separations observed in previous experimental studies, complementary unsteady static pressure measurement campaigns have been conducted on the diffuser blade wall. The unsteadiness revealed by these measurements, as well as theirs effects on the diffuser performance, was then studied.


2001 ◽  
Author(s):  
Ho Joon Park ◽  
Sang Young Son ◽  
Mun Cheol Choi ◽  
Geunbae Lim ◽  
In-Seob Song ◽  
...  

Abstract This paper investigated experimentally effects of the temperature-dependent property on the laminar flow characteristics in the micro-channel, where water was used as a working fluid. A rectangular straight micro-channel was fabricated with the dimension of 57 μm (H) × 200 μm (W) × 48050 μm (L), in which the resistance temperature detectors (RTDs) were integrated to measure precise temperatures of the fluid directly on the inside-surface of the channel wall. A micro-heater was also installed at the outlet of the channel to generate the heat flux. We measured pressure drop by increasing mass flow rate and the applied heating power. At the same time, micro-Particle Image Velocimetry (micro-PIV) [1] measured the detailed velocity fields along the microchannel, where the wall temperature varied. Based on the pressure drop and Micro-PIV measurement, it was determined that the variation of the fluid property along the microchannel has an effect significantly on flow resistance but not considerably on the velocity profile. Also, it was observed that flow resistance and velocity field shows a good agreement with those estimated in the macro laminar theory under our experimental conditions.


Micromachines ◽  
2018 ◽  
Vol 9 (12) ◽  
pp. 668 ◽  
Author(s):  
Kanji Kaneko ◽  
Takayuki Osawa ◽  
Yukinori Kametani ◽  
Takeshi Hayakawa ◽  
Yosuke Hasegawa ◽  
...  

The steady streaming (SS) phenomenon is gaining increased attention in the microfluidics community, because it can generate net mass flow from zero-mean vibration. We developed numerical simulation and experimental measurement tools to analyze this vibration-induced flow, which has been challenging due to its unsteady nature. The validity of these analysis methods is confirmed by comparing the three-dimensional (3D) flow field and the resulting particle trajectories induced around a cylindrical micro-pillar under circular vibration. In the numerical modeling, we directly solved the flow in the Lagrangian frame so that the substrate with a micro-pillar becomes stationary, and the results were converted to a stationary Eulerian frame to compare with the experimental results. The present approach enables us to avoid the introduction of a moving boundary or infinitesimal perturbation approximation. The flow field obtained by the micron-resolution particle image velocimetry (micro-PIV) measurement supported the three-dimensionality observed in the numerical results, which could be important for controlling the mass transport and manipulating particulate objects in microfluidic systems.


2010 ◽  
Vol 8 (3) ◽  
pp. 22-28
Author(s):  
S.R. Jeong ◽  
T.D. Dang ◽  
J.H. Choi ◽  
G.M. Kim ◽  
C.W. Park

Author(s):  
Sang-Joon Lee ◽  
Guk-Bae Kim

Most microfluidic chips consist of several microchannels inside. In order to design microfluidic chips efficiently, it is important to predict the flow passage and to understand the flow characteristics on the chip. In this study, the flow structure inside microchannels has been investigated using a micro-PIV system. We focused on the flow resistance with respect to the inlet configuration of microchannels. The microchannels made of poly-dimethyl-siloxane (PDMS) material were fabricated by a micro-molding technique using SU-8 (photoresist) master. The width (w) and depth of the microchannels were fixed as 100 μm and 58 μm, respectively. Six different inlet configurations with curvature radii in the ranges from r = 0.2w to 1.5w were tested in this study. As a result, with increasing the curvature radius of the inlet corner, the streamwise mean velocity develops slowly in the entrance region, but the fully developed velocity at further downstream is increased. When the curvature radius is larger than r = 0.6w, the reduction rate of flow resistance is not so significant. For the microchannels with r = 0.6w, 0.8w and 1.0w the downstream mean velocity at channel center has nearly the same value of about 276 mm/sec, 10.5% larger than that of r = 0.2w. The simple rounding of microchannel inlet corner reduces flow resistance effectively by smoothing the incoming flow. The length of entrance region is much smaller than that of macro-scale channel.


Author(s):  
Haruyuki Kinoshita ◽  
Marie Oshima ◽  
Jong Wook Hong ◽  
Teruo Fujii ◽  
Tetsuo Saga ◽  
...  

2020 ◽  
Vol 23 (3) ◽  
pp. 449-457 ◽  
Author(s):  
Jihoon Kim ◽  
Si Bui Quang Tran ◽  
Baekhoon Seong ◽  
Hyungdong Lee ◽  
Giho Kang ◽  
...  

2011 ◽  
Vol 308-310 ◽  
pp. 189-192
Author(s):  
Long Xing Chen ◽  
Wen Qi Ma ◽  
He Chun Yu ◽  
Hai Yan Liu ◽  
Hong Wang Du

The aerostatic circular thrust bearing was taken as a study subject. The numerical simulation method was used to calculate the flow passage. Meanwhile, the single-point testing method was used to test the pressure distribution. The simulation and experiment measurement results were compared and analyzed. The results show that: The single-point testing method is effective to capture the change of flow characteristics. The overall results of simulation and testing coincide with each other well. In the range of cone cavity, the flow pattern for the gas is turbulent flow, and the flow field should be divided into different zones for simulation.


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