Stability of Extemporaneously Prepared 0.5-Percent Caspofungin Eye Drops: a Potential Cost-Savings Exercise
2012 ◽
Vol 56
(6)
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pp. 3435-3437
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Keyword(s):
ABSTRACTWhile the successful use of topical caspofungin for patients has been reported, topical caspofungin is not commercially available and its stability is unknown, limiting its usefulness in treating fungal keratitis. Caspofungin (0.5%) eye drops were aseptically prepared, and the concentrations were measured using a validated high-performance liquid chromatography (HPLC) analysis. The preparations remained stable for 28 days under refrigerated condition but not at 25.0°C. Our study supports the cost-saving use of caspofungin eye drops in the clinical setting.
1986 ◽
Vol 49
(5)
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pp. 383-388
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1988 ◽
Vol 68
(1)
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pp. 247-253
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2010 ◽
pp. 263-275
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1999 ◽
Vol 45
(1-2)
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pp. 249-256
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1997 ◽
Vol 25
(01)
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pp. 37-50
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2012 ◽
Vol 50
(2)
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1993 ◽
Vol 100
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pp. 166S-171S
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1994 ◽
Vol 30
(10)
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pp. 153-159
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