Susceptibility of Clostridium difficile Isolates of Varying Antimicrobial Resistance Phenotypes to SMT19969 and 11 Comparators
2015 ◽
Vol 60
(1)
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pp. 689-692
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ABSTRACTWe determined thein vitroactivity of SMT19969 and 11 comparators, including metronidazole, vancomycin, and fidaxomicin, against 107C. difficileisolates of different antimicrobial resistance phenotypes. Fidaxomicin and SMT19969 were the most active. The fidaxomicin and SMT19969 geometric mean MICs were highest in ribotypes known to show multiple resistance. Coresistance to linezolid and moxifloxacin was evident in ribotypes 001, 017, 027, and 356. The high-level ceftriaxone resistance in ribotypes 356 and 018 was location linked.
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2012 ◽
Vol 56
(7)
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pp. 3943-3949
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2012 ◽
Vol 78
(9)
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pp. 3087-3097
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Keyword(s):
2012 ◽
Vol 56
(9)
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pp. 4786-4792
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2014 ◽
Vol 58
(6)
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pp. 3285-3292
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2016 ◽
Vol 60
(4)
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pp. 2528-2531
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Keyword(s):
2014 ◽
Vol 58
(9)
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pp. 5191-5201
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