Synergistic Effects of the Lactobacillus acidophilus Surface Layer and Nisin on Bacterial Growth
2009 ◽
Vol 76
(3)
◽
pp. 974-977
◽
Keyword(s):
ABSTRACT We have previously described a murein hydrolase activity for the surface layer (S-layer) of Lactobacillus acidophilus ATCC 4356. Here we show that, in combination with nisin, this S-layer acts synergistically to inhibit the growth of pathogenic Gram-negative Salmonella enterica and potential pathogenic Gram-positive bacteria, Staphylococcus aureus and Bacillus cereus. In addition, bacteriolytic effects were observed for the Gram-positive species tested. We postulate that the S-layer enhances the access of nisin into the cell membrane by enabling it to cross the cell wall, while nisin provides the sudden ion-nonspecific dissipation of the proton motive force required to enhance the S-layer murein hydrolase activity.
2014 ◽
Vol 8
(3)
◽
pp. 40-45
2012 ◽
Vol 7
(5)
◽
pp. 1934578X1200700
◽
1988 ◽
Vol 55
(4)
◽
pp. 597-602
◽
2008 ◽
Vol 74
(24)
◽
pp. 7824-7827
◽
2011 ◽
Vol 60
(1)
◽
pp. 75-83
◽
2005 ◽
Vol 49
(7)
◽
pp. 2729-2734
◽
2012 ◽
Vol 3
◽
pp. 684-691
◽