scholarly journals Evaluation of Lacticin 3147 and a Teat Seal Containing This Bacteriocin for Inhibition of Mastitis Pathogens

1998 ◽  
Vol 64 (6) ◽  
pp. 2287-2290 ◽  
Author(s):  
Máire P. Ryan ◽  
William J. Meaney ◽  
R. Paul Ross ◽  
Colin Hill
Keyword(s):  
Antimicrobial Activity ◽  
Lactococcus Lactis ◽  
Broad Spectrum ◽  
Lacticin 3147 ◽  
Mastitis Pathogens ◽  
Teat Seal

ABSTRACT Lacticin 3147 is a broad-spectrum bacteriocin produced byLactococcus lactis subsp. lactis DPC3147 which is bactericidal against a range of mastitis-causing streptococci and staphylococci. In this study, both lacticin 3147 and the lantibiotic nisin were separately incorporated into an intramammary teat seal product. The seal containing lacticin 3147 exhibited excellent antimicrobial activity and might form the basis of an improved treatment for the prevention of mastitis in dry cows.

scholarly journals Lactolisterin BU, a Novel Class II Broad-Spectrum Bacteriocin from Lactococcus lactis subsp. lactis bv. diacetylactis BGBU1-4

2017 ◽  
Vol 83 (21) ◽  
Author(s):  
Jelena Lozo ◽  
Nemanja Mirkovic ◽  
Paula M. O'Connor ◽  
Milka Malesevic ◽  
Marija Miljkovic ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Antimicrobial Activity ◽  
Listeria Monocytogenes ◽  
Lactococcus Lactis ◽  
Foodborne Pathogens ◽  
Broad Spectrum ◽  
Solid Phase ◽  
Food Spoilage ◽  
Content Type ◽  
Strong Antimicrobial Activity

ABSTRACT Lactococcus lactis subsp. lactis bv. diacetylactis BGBU1-4 produces a novel bacteriocin, lactolisterin BU, with strong antimicrobial activity against many species of Gram-positive bacteria, including important food spoilage and foodborne pathogens, such as Listeria monocytogenes, Staphylococcus aureus, Bacillus spp., and streptococci. Lactolisterin BU was extracted from the cell surface of BGBU1-4 by 2-propanol and purified to homogeneity by C18 solid-phase extraction and reversed-phase high-performance liquid chromatography. The molecular mass of the purified lactolisterin BU was 5,160.94 Da, and an internal fragment, AVSWAWQH, as determined by N-terminal sequencing, showed low-level similarity to existing antimicrobial peptides. Curing and transformation experiments revealed the presence of a corresponding bacteriocin operon on the smallest plasmid, pBU6 (6.2 kb), of strain BGBU1-4. Analysis of the bacteriocin operon revealed a leaderless bacteriocin of 43 amino acids that exhibited similarity to bacteriocin BHT-B (63%) from Streptococcus ratti, a bacteriocin with analogy to aureocin A. IMPORTANCE Lactolisterin BU, a broad-spectrum leaderless bacteriocin produced by L. lactis subsp. lactis bv. diacetylactis BGBU1-4, expresses strong antimicrobial activity against food spoilage and foodborne pathogens, such as Listeria monocytogenes, Staphylococcus aureus, Bacillus spp., and streptococci. Lactolisterin BU showed the highest similarity to aureocin-like bacteriocins produced by different bacteria. The operon for synthesis is located on the smallest plasmid, pBU6 (6.2 kb), of strain BGBU1-4, indicating possible horizontal transfer among producers.

The Study of Bacillus Subtils Antimicrobial Activity on Some of the Pathological Isolates

2019 ◽  
Vol 9 (02) ◽  
Author(s):  
Hussein A Kadhum ◽  
Thualfakar H Hasan2
Keyword(s):  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Antimicrobial Activity ◽  
Bacillus Subtilis ◽  
Bacterial Growth ◽  
Broad Spectrum ◽  
Inhibitory Activity ◽  
Bacterial Pathogens ◽  
Inhibitory Ability ◽  
Selection Of

The study involved the selection of two isolates from Bacillus subtilis to investigate their inhibitory activity against some bacterial pathogens. B sub-bacteria were found to have a broad spectrum against test bacteria such as Staphylococcus aureus and Pseudomonas aeruginosa. They were about 23-30 mm and less against Klebsiella sp. The sensitivity of some antibodies was tested on the test samples. The results showed that the inhibitory ability of bacterial growth in the test samples using B. subtilis extract was more effective than the antibiotics used.

scholarly journals Antimicrobial activity of Paenibacillus peoriae strain NRRL BD-62 against a broad spectrum of phytopathogenic bacteria and fungi

2003 ◽  
Vol 95 (5) ◽  
pp. 1143-1151 ◽  
Author(s):  
I. Weid ◽  
D.S. Alviano ◽  
A.L.S. Santos ◽  
R.M.A. Soares ◽  
C.S. Alviano ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Broad Spectrum ◽  
Phytopathogenic Bacteria ◽  
Bacteria And Fungi

scholarly journals Draft Genome Sequence of Brevibacillus brevis DZQ7, a Plant Growth-Promoting Rhizobacterium with Broad-Spectrum Antimicrobial Activity

2015 ◽  
Vol 3 (4) ◽  
Author(s):  
Qihui Hou ◽  
Chengqiang Wang ◽  
Xiaoyang Hou ◽  
Zhilin Xia ◽  
Jiangping Ye ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Plant Growth ◽  
Genome Sequence ◽  
Broad Spectrum ◽  
Draft Genome ◽  
Draft Genome Sequence ◽  
Functional Genes ◽  
Plant Growth Promoting ◽  
Brevibacillus Brevis ◽  
Growth Promoting

Brevibacillus brevis DZQ7 is a plant growth-promoting rhizobacterium (PGPR) isolated from tobacco rhizosphere. Here, we report the draft genome sequence of B. brevis DZQ7. Several functional genes related to antimicrobial activity were identified in the genome.

scholarly journals Broad-spectrum antimicrobial activity by Burkholderia cenocepacia TAtl-371, a strain isolated from the tomato rhizosphere

Microbiology ◽  
2018 ◽  
Vol 164 (9) ◽  
pp. 1072-1086 ◽  
Author(s):  
Fernando Uriel Rojas-Rojas ◽  
Anuar Salazar-Gómez ◽  
María Elena Vargas-Díaz ◽  
María Soledad Vásquez-Murrieta ◽  
Ann M. Hirsch ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Broad Spectrum ◽  
Burkholderia Cenocepacia

scholarly journals Broad-spectrum antimicrobial activity of human intestinal defensin 5.

1997 ◽  
Vol 65 (6) ◽  
pp. 2396-2401 ◽  
Author(s):  
E M Porter ◽  
E van Dam ◽  
E V Valore ◽  
T Ganz
Keyword(s):  
Antimicrobial Activity ◽  
Broad Spectrum

scholarly journals Antimicrobial Activity of Biosynthesized Silver Nanoparticles Compared to Standard Antibiotics Used in ORL Infections

2019 ◽  
Vol 70 (7) ◽  
pp. 2571-2573
Author(s):  
Alina Andreea Tischer (Tucuina) ◽  
Delia Berceanu Vaduva ◽  
Nicolae Balica ◽  
Alina Heghes ◽  
Adelina Cheveresan ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Silver Nanoparticles ◽  
Antibiotic Resistance ◽  
Adverse Effects ◽  
Infectious Diseases ◽  
Broad Spectrum ◽  
Bacterial Infections ◽  
New Antibiotics ◽  
Recorded Data

In recent years, bacterial infections in hospitals have grown particularly due to the development of antibiotic resistance. Recent research targets the discovery of new antibiotics that exhibit broad spectrum of action without adverse effects or minimizing adverse effects. In this study, the activity of biosynthesized silver nanoparticles against three bacteria commonly found in infectious diseases in the ORL sphere was evaluated. The recorded data revealed an activity comparable to that of the standard antibiotics used in these types of infections, with the observation that the activity of the nanoparticles could also be observed in the particular cases of antibiotic resistance.

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