scholarly journals Microevolution and Patterns of Dissemination of the JP2 Clone of Aggregatibacter (Actinobacillus) actinomycetemcomitans

2007 ◽  
Vol 75 (6) ◽  
pp. 3080-3088 ◽  
Author(s):  
Dorte Haubek ◽  
Knud Poulsen ◽  
Mogens Kilian
Keyword(s):  
West Africa ◽  
African Descent ◽  
Point Mutations ◽  
Housekeeping Genes ◽  
Mediterranean Area ◽  
Aggressive Periodontitis ◽  
Population Genetic Analysis ◽  
Host Tropism ◽  
The Mediterranean ◽  
Clonal Population Structure

ABSTRACT The natural history, microevolution, and patterns of interindividual transmission and global dissemination of the JP2 clone of Aggregatibacter (Actinobacillus) actinomycetemcomitans were studied by population genetic analysis. The JP2 clone is strongly associated with aggressive periodontitis in adolescents of African descent and differs from other clones of the species by several genetic peculiarities, including a 530-bp deletion in the promoter region of the leukotoxin gene operon, which results in increased leukotoxic activity. Multilocus sequence analysis of 82 A. actinomycetemcomitans strains, 66 of which were JP2 clone strains collected over a period of more than 20 years, confirmed that there is a clonal population structure with evolutionary lineages corresponding to serotypes. Although genetically highly conserved, as shown by alignment of sequences of eight housekeeping genes, strains belonging to the JP2 clone had a number of point mutations, particularly in the pseudogenes hbpA and tbpA. Characteristic mutations allowed isolates from individuals from the Mediterranean area and from West Africa, including the Cape Verde Islands, to be distinguished. The patterns of mutations indicate that the JP2 clone initially emerged as a distinct genotype in the Mediterranean part of Africa approximately 2,400 years ago and subsequently spread to West Africa, from which it was transferred to the American continents during the transatlantic slave trade. The sustained exclusive colonization of individuals of African descent despite geographical separation for centuries suggests that the JP2 clone has a distinct host tropism. The colonization of family members by JP2 clone strains with unique point mutations provides strong evidence that there is intrafamilial transmission and suggests that dissemination of the JP2 clone is restricted to close contacts.

Spatial Distribution of Pre-Warm Front Rainfall in the Mediterranean Area

1988 ◽  
Vol 19 (1) ◽  
pp. 53-64 ◽  
Author(s):  
C. Corradini ◽  
F. Melone
Keyword(s):  
Mediterranean Area ◽  
Compact Structure ◽  
Large Variability ◽  
Air Mass ◽  
Orographic Effects ◽  
Warm Front ◽  
Average Rainfall ◽  
Convective Motions ◽  
Rainfall Type ◽  
The Mediterranean

Evidence is given of the distribution of pre-warm front rainfall at the meso-γ scale, together with a discussion of the main mechanisms producing this variability. An inland region in the Mediterranean area is considered. The selected rainfall type is commonly considered the most regular inasmuch as it is usually unaffected by extended convective motions. Despite this, within a storm a large variability in space was observed. For 90% of measurements, the typical deviations from the area-average total depth ranged from - 40 to 60 % and the storm ensemble-average rainfall rate over an hilly zone was 60 % greater than that in a contiguous low-land zone generally placed upwind. This variability is largely explained in terms of forced uplift of air mass over an envelope type orography. For a few storms smaller orographic effects were found in locations influenced by an orography with higher slopes and elevations. This feature is ascribed to the compact structure of these mountains which probably determines a deflection of air mass in the boundary layer. The importance of this type of analysis in the hydrological practice is also emphasized.

Warfare and Environment in the Ancient World

2013 ◽  
pp. 127-140
Author(s):  
J. Donald Hughes
Keyword(s):  
Natural Environment ◽  
Armed Conflict ◽  
Near East ◽  
Mediterranean Area ◽  
Ancient World ◽  
Direct Effects ◽  
Environmental Properties ◽  
The Mediterranean ◽  
Ancient Warfare ◽  
The Military

This chapter deals with ancient warfare and the environment. Hunting was often been considered as a form of warfare, and art frequently portrayed humans in battle with animals. Armed conflict had its direct influences on the environment. Along with damage to settled agriculture, warfare had affected other lands such as pastures, brush lands, and forests. It is noted that birds, pigs, bears, rodents, snakes, bees, wasps, scorpions, beetles, assassin bugs, and jellyfish have been employed as weaponized animals in ancient warfare, which, in the Mediterranean area and Near East, had vital environmental properties. The direct effects of battle have been shown by ancient historians, but just as important were the influences of the military-oriented organization of societies on the natural environment and resources.

scholarly journals Migrants’ Sexual Violence in the Mediterranean Region: A Regional Analysis

Sexes ◽  
2021 ◽  
Vol 2 (3) ◽  
pp. 305-314
Author(s):  
Demetris Hadjicharalambous ◽  
Stavros Parlalis
Keyword(s):  
Health Care ◽  
Sexual Violence ◽  
Mediterranean Region ◽  
Clinical Care ◽  
Regional Analysis ◽  
Mediterranean Area ◽  
International Literature ◽  
Migrant Women ◽  
Promote Gender Equality ◽  
The Mediterranean

Migration in the Mediterranean region has increased greatly during the last years. Reports and studies reveal that violence and injuries among refugees and migrants is a common occurrence in the WHO Europe Region. Available literature indicates that sexual violence incidents take place: (a) during the migratory journey to the host country, (b) while in detention centers, (c) once migrants have reached their destination, and (d) during the period in which a woman is subject of trafficking. This manuscript explores how sexual violence against refugee/immigrant women is presented in the international literature; a narrative review of the literature was conducted on the phenomenon of migration in the Mediterranean area, and specifically on sexual violence of migrant women. In order to face the challenges faced by migrant women victims of sexual violence, the following policies are suggested by international literature: (a) offer emergency medical and health care to sexual violence survivors, which is usually relatively limited, (b) offer mental health care and psychological support for sexual violence when planning services to provide clinical care, and (c) work towards the aim of transforming norms and values in order to promote gender equality and support non-violent behaviours.

scholarly journals Special Issue “Focus on the Salinization Issue in the Mediterranean Area”

Water ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 681
Author(s):  
Micòl Mastrocicco
Keyword(s):  
Mediterranean Region ◽  
Mediterranean Area ◽  
Precipitation Pattern ◽  
Special Issue ◽  
The Mediterranean

Throughout the Mediterranean Region, recent and past studies have highlighted an increase in temperature, especially during summer, a decrease in precipitation and a change in the in-year precipitation pattern [...]

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