Construction and Characterization of an Isogenicslt-ii Deletion Mutant of EnterohemorrhagicEscherichia coli
1998 ◽
Vol 66
(5)
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pp. 2337-2341
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Keyword(s):
E Coli
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ABSTRACT Enterohemorrhagic Escherichia coli (EHEC) produces Shiga-like toxins (SLT), potent protein synthesis inhibitors. To further dissect the role of SLT-II in the course of disease, we have constructed E. coli TUV86-2, an isogenic SLT-II-negative mutant of EHEC strain 86-24. The slt-ii gene was inactivated by suicide vector mutagenesis. We also isolated derivatives of strain 86-24 that were cured of the phage carrying the toxin genes.
2012 ◽
Vol 78
(19)
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pp. 6799-6803
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2000 ◽
Vol 182
(21)
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pp. 6247-6249
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1999 ◽
Vol 67
(5)
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pp. 2103-2109
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1994 ◽
Vol 180
(6)
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pp. 2147-2153
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