Signaling via Toll-Like Receptor 5 Can Initiate Inflammatory Mediator Production by Murine Osteoblasts
2003 ◽
Vol 71
(9)
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pp. 5418-5421
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Keyword(s):
ABSTRACT Murine osteoblasts express Toll-like receptor 5 (TLR5), and this expression is upregulated following exposure to bacteria or to the TLR5 agonist, flagellin. Importantly, flagellin activates transcriptional regulators and elicits proinflammatory cytokine production, suggesting TLR5 functionality. TLR5 may represent an important mechanism underlying the recognition of bacterial pathogens by osteoblasts during bone infections.
2009 ◽
Vol 29
(4)
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pp. 347-367
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2015 ◽
Vol 402
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pp. 1-12
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2020 ◽
Vol 79
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pp. 106085
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2011 ◽
Vol 71
(1)
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pp. 80-83
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2003 ◽
Vol 75
(2)
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pp. 342-349
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2018 ◽
Vol 2018
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pp. 1-8
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2007 ◽
Vol 120
(1)
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pp. 69-75
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