Induction of De Novo Subcortical Actin Filament Assembly by Treponema denticola Major Outer Sheath Protein
2004 ◽
Vol 72
(6)
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pp. 3650-3654
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Keyword(s):
De Novo
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ABSTRACT Treponema denticola and its major outer sheath protein (Msp) induce actin reorganization in fibroblasts. We adapted a barbed-end labeling/imaging assay to monitor Msp-induced subcortical actin filament assembly in neutrophils and fibroblasts. Msp, at an actin-reorganizing concentration, inhibited migration of these dissimilar cell types, whose cytoskeletal functions in locomotion and phagocytosis are crucial for immunity and healing of peripheral infections.
1998 ◽
Vol 143
(7)
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pp. 1919-1930
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Keyword(s):
2001 ◽
Vol 226
(4)
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pp. 283-295
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